This article assesses the impact of the discovery of bacteriophages, which emerged from an investigation into a 1915 outbreak of bacillary dysentery in France, on influenza virus research. Specifically, it details the way in which the phages became a vehicle for importing certain assay techniques into the study of influenza and other viruses that cause infectious diseases in humans and other animals, thereby enabling the scaling up of vaccine production for these diseases. Very soon after his 1917 report of the discovery of bacteriophages, Felix d’Herelle developed an assay technique based on their ability to form countable plaques on solid media when incubated along with the dysentery bacteria. This basic technique was further refined by Macfarlane Burnet in the late 1920s. Still later, in the wake of a 1935 influenza outbreak in Australia, Burnet applied the principles of serial dilution and plaque counting, honed during his work on the phages, to develop a technique for cultivating influenza viruses in fertilised eggs and assaying them by counting the pocks induced on the chick embryo membranes. The ability to grow and assay these viruses proved crucial in developing the first successful vaccines against influenza. In the 1950s, bacteriophage assay techniques were once more carried over to the assaying of viruses on cultured cells by Renato Dulbecco and Marguerite Vogt. The importance of quantification in science, as well as the ability to apply the results of investigations in one area of biology to another, relatively unrelated field, is also discussed.

With this paper, I suggest focusing on diplo-scientific actors as a fruitful approach to study how certain actors have helped to shape international organisations through their diplomatic activities and scientific practices. Using the example of the Swedish medical physicist Rolf Sievert, I show how Sievert’s personality and preferences came to decisively shape the post-war trajectory of the International Commission on Radiation Protection (ICRP) and more broadly the international landscape of radiation protection. In the inter-war period, Sievert was engaged in the ICRP and its mother organisation, the International Radiological Congress (IRC), dealing with the interwoven questions of how to formulate international radiation standards and radiation protection initiatives. Following the Second World War, Sievert became concerned with the proliferation of nuclear technologies and the spread of radioactive fallout following nuclear test bombings. Because of this concern, Sievert set out to separate the ICRP from the IRC and form a new, independent group that could deal with the dangers of the new ‘Nuclear Age’. While Sievert was ultimately unsuccessful, his attempts would decisively change the purview and trajectory of the ICRP. This had large ramifications, as the ICRP continues to be the prime international organisation on radiological and medical radiation protection, formulating recommendations that are used by international, regional, national, and local groups, informing epistemic judgements on radiation research.

This article examines the evolution of breastfeeding practices in twentieth-century China, focusing on the complex interplay between medical knowledge, state policies and social transformation. This study demonstrates how medical recommendations concerning lactation timing, intervals and weaning were shaped by factors beyond purely scientific developments. Mid-twentieth-century biochemical studies validated traditional practices while revolutionising attitudes towards colostrum, marking a critical juncture in Chinese infant nutrition science. Following the establishment of the People’s Republic in 1949, maternal and child health initiatives underwent fundamental changes. Drawing on new understanding of breast milk’s nutritional value, health benefits, and economic advantages, healthcare professionals and state authorities actively promoted scientific breastfeeding methods. Their multifaceted approach reflected both the dissemination of medical knowledge and the state’s strategic consideration of female labour force participation. This study analyses how women’s liberation from feudal constraints, changing employment patterns, Soviet medical influence, and advances in artificial feeding technologies shaped breastfeeding practices. Through examining the intersection of medical advice, health policies, and women’s labour liberation, it provides fresh insights into the evolution of breastfeeding discourse within Chinese medical circles. Situating these developments within broader medical, social and cultural contexts, this research not only illuminates the multiple factors that shaped modern Chinese infant feeding practices but also contributes to our understanding of the complex relationships between medical practice, state policy, and social change in twentieth-century China.

In this article we trace a biography of vacuum aspiration in Spain between the 1960s and 1980s. Analysing the local but transnationally connected history of vacuum aspiration during late Francoism and the democratic transition, we argue that this technology was since the mid-1960s reincarnated in mainstream medical discourse as vacuum curettage, presented as a major medical innovation in diagnosis and therapy. While abortion activists working at the end of the 1970s emphasized the group and political components of a technique they called the ‘Karman method’, doctors performing illegal abortions within the family planning network defined vacuum aspiration in terms of safety and medical innovation. As we demonstrate, this technique embodied meanings that at times overlapped, at others conflicted, contingent on whether aspirations were linked to medical innovation, pro-abortion activism, or social justice.

Ghostwriting autobiographies has gained so high a profile that novels and films focus on the ghost. To deepen understanding of such collaborations in science and medicine, this article reconstructs the making of A Matter of Life (1980), ‘the sensational story of the world’s first test-tube baby’. Although critiqued by feminist scholars, revised through research and embellished in fiction, this double autobiography of Robert Edwards and Patrick Steptoe is still the standard history of the British team’s work to achieve in vitro fertilisation (IVF). It is thus high time to investigate the debt acknowledged only by ‘gratitude for his invaluable help’ to the physician and poet Dannie Abse. I use previously unexploited manuscripts to illuminate relationships among authors, rewriter, and editor, and among those they cast as involved in the research. The records show that Abse rewrote underwhelming drafts for a publisher that had bought and sold the doctors’ story of the ‘baby of the century’ and needed a bestseller. To engage readers, he reworked the text so that alleviating infertility appeared as a career-long quest. As a result of adding vivid scenes with characters and expository dialogue, Abse began to give women—wives, assistants and patients—larger roles in the drama. The objections of Edwards and his circle to various literary references and factual claims were overruled. Yet the authors came across more sympathetically, and IVF was promoted more effectively, than in their own drafts. The process puts recent retellings of the story into perspective and exemplifies how collaboration can shape scientific and medical autobiographies.

Addiction was considered ‘alien to Socialism’. At least, that was the narrative upheld by the socialist East German state, which thus followed the traditional argumentation of socialist and social democratic movements since the turn of the century. While the state clung to this ideological claim, the consumption and abuse of beer, spirits, and benzodiazepines continued to increase. However, there was never a central strategy for the treatment and prevention of addiction in the German Democratic Republic (GDR). The hesitation and ignorance of the state authorities created a vacuum that was filled by local initiatives and expert discussions aimed at improving the situation of people with addictions. In this article, I analyse the introduction of new treatment methods in a psychiatric hospital in the GDR and show that doctors, psychologists, patients, and local officials had certain freedoms to test new approaches, many of which originated in the West. Even though they had to adapt concepts such as the ‘therapeutic communities’ of British reformer Maxwell Jones to the specific socialist and East German context to avoid restrictions by state authorities, the Berlin Wall did not prevent the transfer of knowledge. This article, therefore, paints a nuanced picture of the therapeutic methods used to treat people with addiction in the GDR. From condemning individuals as outcasts of socialist society for socially deviant drinking behaviour and relying exclusively on aversion therapy and moral accusations, there was a shift towards a mixture of treatments that became increasingly specialised and individualised, especially in the 1970s and 1980s, comparable to Western standards.

The article focuses on the export of cadaveric pituitary glands from communist Bulgaria in the 1980s, used for the production of human growth hormone. The case is explored in the broader context of practices and transnational networks for the supply of pituitaries. Special attention is paid to the changes resulting from the turn to the production of recombinant growth hormone in the mid-1980s, which put an end to the international ‘market’ of pituitary glands. In the last sections, different perspectives are explored to make sense of the case under scrutiny: those of bioethics and biolaw, on the one hand, and of bioeconomy in a globalising world, on the other.

The presence of children in eighteenth-century English voluntary hospitals is an area of increasing interest and attention. The Northampton Infirmary admission records detail inpatient and outpatient ages from 1744 to 1804, allowing for longitudinal investigations of children in the institution. The most common distempers affecting children were surgical infections, infectious diseases, and skin diseases; fifty-six per cent of the child patients were male and 43.3 per cent were female. Nearly seventy-five per cent of children left the hospital ‘cured’. This article outlines the Northampton Infirmary Eighteenth Century Child Admission Database, and demonstrates how the patterning of distempers within and among children provides insight into the health journeys of eighteenth-century children through the lens of their bodies, their parents, and their institutional recommenders.

Following the trajectories of vaccines against foot-and-mouth disease (FMD) in France and Britain up to the 1960s, this paper will show how vaccine efficacy has two meanings: 1) technical – or experimental – which refers to test protocols and regimes of evidence, and 2) practical – or experiential – which refers to the experience various actors have of diseases and their direct or indirect impacts on society and the economy, as well as on representations and imaginaries they share about diseases, vaccines, and vaccination. The assessment protocols in the two countries are analysed to show how these two meanings are deeply intertwined and influence the different public policies chosen by each country. Although statistically assessed, the efficacy of the same vaccines appears situated, depending not only on regimes of evidence but also on the reality of agricultural practices, on national stock exchanges, and on various imaginaries about animal health and the absence of disease that differ between and within countries. As a consequence, this analysis reveals how public policies regarding vaccination do not always come from governmental incentives but can also emerge from private and local initiatives.

This article explores the intersection of Cold War geopolitics, cultural psychiatry, and migration in Taiwan from the mid-1940s to the 1970s. Building on recent scholarship in cultural psychiatry and Cold War science, it examines how geopolitical tensions shaped psychiatric knowledge production in East Asia. Focusing on the psychological and social impact of the 1949 mass migration, when over a million Chinese immigrants arrived in Taiwan, alongside the clinical and academic work of Taiwanese psychiatrists, the study highlights how migration and societal upheaval became central research concerns. Operating under the authoritarian Kuomintang regime and within the constraints and opportunities of international politics, Taiwanese psychiatrists – most of whom were native-born with colonial backgrounds – drew on intellectual traditions from imperial Japan, fascist Germany, and the Cold War Western bloc. Navigating both global psychiatric discourses and local concerns, they positioned themselves as key contributors to the international development of psychiatric research. While their portrayals of Chinese character structure and family dynamics sometimes reflected essentialist views, their work also demonstrated a nuanced awareness of historical change and contemporary realities during a period of intense political repression and uncertainty. By analysing archival sources and medical texts, this article illuminates the complex interplay between geopolitics and psychiatric knowledge production in Cold War Taiwan.

This paper examines the history of the ‘lower cavity’ of the gastrointestinal tract, a distinctive anatomical feature in Greco-Roman medicine that described a second stomach-like organ in the large intestine. It traces how a bipartite model of the digestive system emerged in fourth-century bce Greek medical and philosophical thought and persisted in the works of influential figures such as Galen, Vesalius, and Glisson, despite shifts in terminology, anatomical observations, and physiological theories. The study demonstrates that this understanding arose primarily from three complementary factors: a specific terminology that paired the stomach with a lower cavity, systematic animal dissections that revealed pronounced caeca in certain species, and emerging physiological theories that required separate bodily receptacles for digested food and residues. Through this case study, the paper illuminates how premodern anatomical knowledge was articulated by a constant negotiation between animal bodies, human bodies, and past textual authorities, facilitating the surprising longevity of ideas like the ‘lower cavity’ in the gastrointestinal tract.

This article explores the cultivation of medical knowledge via popular health guides among the Finnish lay populace from the 1890s to the 1970s. By using written reminiscences and newspaper articles as source material, the article discusses the relevance, popularity, and practical use of various printed health guides and manuals throughout Finland. We place particular focus on the late nineteenth to the early twentieth century as the period that experienced a high increase in lay education and literacy. By focusing on individual readers and their experiences of popular health guides, the article examines lay medical and health practices as the number of medical manuals dramatically increased from the late nineteenth century onwards. It also investigates the reception of medical, popular and irregular health movements, such as hygienism, nature cure, and Couéist autosuggestion, and the change in medical culture brought about by the appearance of patent medicines. As the information discovered in popular health guides tended to fluctuate between official and irregular medical theory, we analyse the relationship between learned, alternative, and vernacular medicine through the views and opinions expressed by people who engaged with health literature. Through these materials, we provide a novel understanding of the accessibility of medical knowledge, the spread and impact of health guides, and attitudes towards different medical practices among the Finnish reading public.

Surgical sterilisation practices significantly increased in contraceptive capacity as the twentieth century unfolded. Despite this prolific uptake, sterilisation is markedly absent from histories of birth control and family planning and instead has remained addressed within histories of eugenics and coercion. The purpose of this article is twofold: firstly, to demonstrate a voluntary, contraceptive history of sterilisation that is distinct from, though connected to, involuntary and eugenic sterilisation; and secondly, to explain the integral role that individual doctors and their private practice played in the rise of contraceptive sterilisation in twentieth-century Australia. Through a combination of archival material and oral history interviews with twentieth-century practitioners of tubal ligation and vasectomy, this article reframes the history of surgical sterilisation, situating it firmly within the history of birth control.

This article is concerned with the history of eugenic sterilisation in Britain through the 1920s and 1930s. In this period, the Eugenics Society mounted an active but ultimately unsuccessful campaign to legalise the voluntary surgical sterilisation of various categories of people, including those deemed ‘mentally deficient’ or ‘defective’. We take as our explicit focus the propaganda produced and disseminated by the Eugenics Society as part of this campaign, and especially the various kinds of data mobilised therein. The parliamentary defeat of the Society’s Sterilisation Bill in July 1931 marks, we argue, a significant shift in the tactics of the campaign. Before this, the Eugenics Society framed sterilisation as a promising method for eradicating, or at least significantly reducing the incidence of, inherited ‘mental defect’. Subsequently, they came to emphasise the inequality of access to sterilisation between rich and poor, (re)positioning theirs as an egalitarian campaign aimed at extending a form of reproductive agency to the disadvantaged. These distinct phases of the campaign were each supported by different kinds of propaganda material, which in turn centred on very different types of data. As the campaign evolved, the numbers and quantitative rhetoric which typified earlier propaganda materials gave way to a more qualitative approach, which notably included the selective incorporation of the voices of people living with hereditary ‘defects’. In addition to exposing a rupture in the Eugenics Society’s propagandistic data practices, this episode underscores the need to further incorporate disabled dialogues and perspectives into our histories of eugenics.

Cross-gender behaviour gradually entered the spheres of aetiology and diagnosis during the eighteenth century with reference to scattered instances of male cross-dressing. But well into the nineteenth century, “gender identity” (a mid-twentieth-century term) remained a poorly theorised instance of medicalisation. Late eighteenth-century concepts of “dynamic hermaphroditism” accounted for gender-nonconforming behaviours and aspirations, but could not account for the observed heterogeneity in disparities between sexed body and mind. Increasingly substantive contributions to aetiology were seen during the late 1870s and 1880s, particularly in response to Carl Westphal’s convoluted, 1869 concept of “contrary sexual feeling” (conträre Sexualempfindung). Richard von Krafft-Ebing’s notion of metamorphosis sexualis paranoica provided one of the most authoritative approaches to the question of gender identification in “sexual inversion”. The notion, which took the first seven German editions of his Psychopathis sexualis to achieve a definitive formulation, needs to be seen in light of Krafft-Ebing’s earlier conceptions of sexual delusion, which straddled the realms of the experienced sexual body and sense of self. Moreover, Krafft-Ebing was not the first to outline a theory of non-cisgender identity, as demonstrated by the mid-1880s work of Théodule-Armand Ribot and Rudolph Arndt, as well as various significantly earlier approaches to what had been considered the “monomania of sexual transformation”.

While the plague of Provence is the most studied outbreak of the disease in early modern Europe, there is little in the extensive historiography on this topic about fears of the cross-species transmission of disease which re-emerged in the early eighteenth century because of events in southwestern France. Concerns about the interplay between cattle murrains and human plague resurfaced in the early eighteenth century because the plague of Provence followed an outbreak of cattle disease which swept across Europe and killed tens of thousands of animals. This article focuses on the debate about the spread of contagious diseases between species which occurred in Britain during this time. Links between the health of animals and that of humans became objects of heated discussion especially following the issuing of the 1721 Quarantine Act, which was designed to prevent the plague currently ravaging southwestern France from taking hold in Britain. It then considers the different beliefs regarding contagion and the transmission of diseases between different species during the plague of Provence. While focusing on the richly documented and highly revealing discussions in early eighteenth-century Britain about the interplay between plague in cattle and plague in humans, it also utilises materials from earlier centuries to examine more fully how early modern populations understood the relationship between plague in humans and cattle murrains.

Galen’s most deeply held professional values included clarity of expression and the epistemological importance of clinical experience. Therefore, it is not surprising that he thought and wrote about communication with patients. His stories about patients show that he questioned them about their symptoms and history, and some stories explicitly teach the lesson that this type of questioning is important. His stories often quote patients indirectly or directly; they are often told partly from the patient’s perspective, and some contain constructions indicating that Galen paid attention to an individual patient’s exact words. In On the Affected Parts, his discussion of the vocabulary of pain – a problem in medical communication still important today – he privileges the common usage of patients over the technical vocabulary invented by Archigenes. He argues that only by listening to patients and their words can we construct a useful vocabulary of metaphors for pain that can bridge the gap in experience between physician and patient. He does not dismiss the words of women or enslaved patients; on the other hand, in a few stories where the patriarch of a family is present and the patient is female or enslaved, Galen’s dialogue tends to engage the head of the household rather than the patient. While some of his stories show off his ability to diagnose patients without talking to them, and others raise the problem of the lying patient, none of these stories would have meaning unless the patients’ words were normally crucial to clinical practice.

When kidney transplantation evolved from an experimental into a clinical treatment of end-stage renal disease (ESRD) in the 1960s, it was conceptualised as a collaborative therapy. Before specific immunosuppressants were introduced in the 1980s, the best chances for patient and graft survival were expected from finding ‘good’ matches between donor and recipient tissues. Therefore, the pioneers of clinical transplantation in Europe started to recombine their growing patient pools. They created trans-border organ exchange organisations such as Eurotransplant and Intertransplant, based on shared patient databases.

The article traces international and transnational co-operation in kidney exchange using the example of state-socialist Germany. How did the German Democratic Republic (GDR) get involved with the interconnected networks of knowledge, data, and organ exchange in ESRD treatment? In what ways did the domestic system of kidney transplantation depend on intra- and trans-bloc exchange? How did the GDR profit, and what did it have to offer on an international scale, both in the First and the Second World? The article sheds light on the under-explored transplantation history of the socialist East and thereby investigates the possibilities and limits of trans-bloc collaboration in Cold War Europe.

In recent years, the digitisation of historical data containing cause-of-death information has significantly increased. However, these data show considerable variations in diagnostic practices and nosology over time and place. Examining vague historical causes of death, often denoting symptoms rather than specific diseases, is a particular challenge. Infantile convulsions are an example of a common yet problematic cause of death. To improve our understanding of infantile convulsions, we propose an innovative mixed-methods, comparative approach. This study combines qualitative analyses of historical medical thinking on infantile convulsions with quantitative analyses of individual-level death records from four European cities: Amsterdam, Hermoupolis, Maastricht, and Rostock, covering different periods between 1800 and 1955. Our findings reveal that infant deaths attributed to convulsions encompass a multitude of causes from different disease categories. Significant differences emerged in the patterns of convulsions across time, age groups, and locations, even within the same country. The decline in convulsions mortality seems to be more related to the introduction of uniform registration regulations and systems, and advancements in medical knowledge than to the decline in overall infant mortality. This study’s outcome serves as a cautionary note that challenges the prevailing attitude towards convulsions and emphasises the complexity of interpreting deaths from convulsions. These were highly dependent on historical context, especially local medical culture and the variable accuracy of cause-of-death registration. These findings have implications for studies on infant mortality even when the main interest of such studies is not convulsions mortality.