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Within the USA military, monitoring body composition is an essential component of predicting physical performance and establishing soldier readiness. The purpose of this study was to explore mobile phone three-dimensional optical imaging (3DO), a user-friendly technology capable of rapidly obtaining reliable anthropometric measurements and to determine the validity of the new Army one-site body fat equations using 3DO-derived abdominal circumference. Ninety-six participants (51 F, 45 M; age: 23·7 ± 6·5 years; BMI: 24·7 ± 4·1 kg/m2) were assessed using 3DO, dual-energy X-ray absorptiometry (DXA) and a 4-compartment model (4C). The validity of the Army equations using 3DO abdominal circumference was compared with 4C and DXA estimates. Compared with the 4C model, the Army equation overestimated BF% and fat mass (FM) by 1·3 ± 4·8 % and 0·9 ± 3·4 kg, respectively, while fat-free mass (FFM) was underestimated by 0·9 ± 3·4 kg (P < 0·01 for each). Values from DXA and Army equation were similar for BF%, FM and FFM (constant errors between −0·1 and 0·1 units; P ≥ 0·82 for each). In both comparisons, notable proportional bias was observed with slope coefficients of −0·08 to −0·43. Additionally, limits of agreement were 9·5–10·2 % for BF% and 6·8–7·8 kg for FM and FFM. Overall, while group-level performance of the one-site Army equation was acceptable, it exhibited notable proportional bias when compared with laboratory criterion methods and wide limits of agreement, indicating potential concerns when applied to individuals. 3DO may provide opportunities for the development of more advanced, automated digital anthropometric body fat estimation in military settings.
The engraved slate plaques were part of an extensive and variable class of ritual objects in Late Neolithic and Copper Age Iberia, with Classic plaques being the most numerous and standardized type. Classic plaques have a top and base separated by a horizontal line or bands, and base registers of repeating design elements (triangles, checkerboard, etc.). Associated with burials, they have been interpreted as genealogical records, with their base design referencing a clan or other social unit and their number of registers denoting the generational distance of the deceased from an important ancestor. The authors evaluate the genealogical hypothesis using a larger dataset than available when originally proposed, employing statistical analyses to examine the relationship between the number of registers and find locations, and between design elements and tomb size. Tomb size is viewed as a measure of collective labour, and hence a proxy of the status of the individuals in the tomb. These analyses show significant patterning between the number of registers and the plaques’ geographic distribution, and between specific design elements and tomb size, suggesting that the genealogical hypothesis remains a plausible explanation for the Classic plaques.
The United States has long represented one of Canada's primary international allies. This partnership has remained strong despite turbulent times in the relationship, such as the one brought forth by the Trump presidency. Our article seeks to understand the sources of such continuity through the lens of continentalism. While historical accounts of continentalism have portrayed it as a passive force stemming from Canada's material self-interest, scholars have recently identified the emergence of an evolved form of continentalism that represents a dominant idea and a coherent analytical framework in Canadian foreign policy. Has this new form of continentalism indeed gained widespread acceptance among Canadians? We answer this question by considering continentalism in the ideational realm. Using novel public opinion data, our analysis investigates whether continentalist attitudes have become embedded in Canadians’ national identity and foster closer alignment preferences vis-à-vis the United States. We find significant and robust evidence of such effects.
To evaluate the rates of use of restrictive practices (RPs), such as seclusion and physical restraint, in approved mental health centres (ACs) in Ireland.
Methods:
Examination of data reported to the regulator of mental health in Ireland, the Mental Health Commission (MHC), and the Health Research Board (HRB).
Results:
There has been a substantial reduction in RP use in Irish ACs between 2018 and 2022.
Conclusions:
The MHC welcomes this reduction in RP use and considers several possible reasons for this data.
DNA profiles of 92 banana and plantain cultivars were generated with 12 amplified fragment length polymorphism (AFLP) primer pairs. The average polymorphism information content (PIC) values of the polymorphic AFLP markers varied from 0.270 to 0.341, and the profiles could distinguish all the 92 cultivars analysed. It was possible to identify differences between two accessions of the AAB genome cultivar Rasthali, indicating the presence of intra-cultivar genetic variation. A UPGMA (unweighted pair group method of arithmetical means) dendrogram generated with 1581 AFLP products identified four major clusters, each comprising cultivars of similar genomic constitution. All the ABB cultivars grouped in a single cluster, which was well separated from the rest. The within-group similarity coefficients indicated that the most diverse group was AAB, followed by AAA. However, significant genetic diversity was also present among AA, AB and ABB Indian banana cultivars, supporting the notion that India, along with other neighbouring south-eastern Asian countries, is the centre of diversity for cultivars of banana and plantain. The presence of substantial diversity among the banana and plantain landrace cultivars could be exploited in varietal improvement programmes.
Representation scholarship has drawn from intersectionality theory 0to examine how systemic structures of oppression and privilege have created social groups with distinct political needs. Derived from Black feminist theory that recognizes that identities are mutually constitutive and interconnected, intersectionality research is rooted in the lived experiences of marginalized groups who call attention to social (in)justice. Empirical scholarship building on the insights of Black feminist theorists such as Collins and Bilge (2016), Hill Collins (1990), Crenshaw (1989; 1991), and King (1988) has constituted nothing less than a paradigm shift in the study of gender and politics. Nevertheless, there remain an array of opportunities to expand upon the potential for intersectional frameworks and methods, as well as pressing new questions concerning the operationalization of intersectionality itself. This Critical Perspectives section offers a moment to take stock of these developments and debates, as well as to highlight new pathways for scholarship committed to centering the margins and considering the nexus of multiple power structures that frame our political lives.
Time-resolved two-dimensional two-component particle image velocimetry measurements with high spatial resolution are carried out in a water tank agitated by four blades rotating at constant speed. Different blade geometries and rotation speeds are tested for the purpose of modifying turbulent flow conditions. In all cases where no baffles are used to break the rotation, the Zeman length is an order of magnitude smaller than the Taylor length. Compared with the cases with baffles which break the rotation, in the unbaffled cases turbulence production and/or mean advection are significant and the turbulence nonlinearity is dramatically reduced for the horizontal (i.e. normal to the axis of rotation) two-point turbulence fluctuating velocities. This nonlinearity reduction is manifest not only in the interscale turbulent energy transfer but also in the interspace turbulent energy transfer, which nearly vanishes. However, the nonlinearity is not reduced for the vertical two-point turbulence fluctuating velocities: the corresponding interscale turbulent transfer rate is in fact intensified, and its dependence on the two-point separation distance, as well as that of the corresponding interspace turbulent transfer rate, which does not vanish, is significantly modified. Even though non-homogeneities are very different for different blades and rotation speeds in the unbaffled cases, the horizontal fluctuating velocity's second-order structure function collapses with scalings which resemble predictions for homogeneous turbulence subject to strong rotation. The vertical fluctuating velocity's second-order structure function does not collapse for different blade geometries by neither these nor the Kolmogorov predictions.
Emerging evidence suggests that low-grade systemic inflammation plays a key role in altering brain activity, behaviour and affect. Modulation of the gut microbiota using prebiotic fibre offers a potential therapeutic tool to regulate inflammation, mediated via the production of short-chain fatty acids (SCFA). However, the impact of prebiotic consumption on affective symptoms and the possible contribution from inflammation, gut symptoms and the gut microbiome are currently underexamined. In this 12-week study, the effects of a diverse prebiotic blend on inflammation, gut microbiota profiles and affective symptoms in a population with metabolic syndrome (MetS) were examined. Sixty males and females with MetS meeting the criteria for MetS were randomised into a treatment group (n 40), receiving 10 g per day of a diverse prebiotic blend and healthy eating advice, and a control group (n 20), receiving healthy eating advice only. Our results showed a significant reduction in high sensitivity C-reactive protein (hs-CRP) in the treatment (–0·58 [–9·96 to–2·63]) compared with control (0·37 [–3·64 to–3·32]), alongside significant improvements in self-reported affective scores in the treatment compared with the control group. While there were no differences in relative abundance between groups at week 12, there was a significant increase from baseline to week 12 in fecal Bifidobacterium and Parabacteroides in the treatment group, both of which are recognised as SCFA producers. Multivariate regression analyses further revealed an association between gastrointestinal symptoms and hs-CRP with affective scores. Together, this study provides preliminary support for a diverse prebiotic blend for mood, stress and anxiety.
Do recent increases in women’s representation around the world have implications for international relations? We argue that greater representation of women in legislatures increases the likelihood of human rights treaty ratification for two reasons. First, given their shared gendered experiences of exclusion and discrimination, women legislators will advocate on behalf of marginalized groups on an international scale as transnational surrogate representatives. Second, women legislators may be more inclined to prioritize the ratification of human rights treaties because these treaties align with their domestic policy preferences, which aim to support marginalized groups. We contend that, in countries where ratification depends upon legislative approval, legislatures are more likely to ratify human rights treaties as women’s presence increases. Using an original dataset of 201 multilateral treaties, we find that countries become more likely to ratify human rights treaties as levels of women’s legislative representation increase.
Given an $n\times n$ symmetric matrix $W\in [0,1]^{[n]\times [n]}$, let ${\mathcal G}(n,W)$ be the random graph obtained by independently including each edge $jk\in \binom{[n]}{2}$ with probability $W_{jk}=W_{kj}$. Given a degree sequence $\textbf{d}=(d_1,\ldots, d_n)$, let ${\mathcal G}(n,\textbf{d})$ denote a uniformly random graph with degree sequence $\textbf{d}$. We couple ${\mathcal G}(n,W)$ and ${\mathcal G}(n,\textbf{d})$ together so that asymptotically almost surely ${\mathcal G}(n,W)$ is a subgraph of ${\mathcal G}(n,\textbf{d})$, where $W$ is some function of $\textbf{d}$. Let $\Delta (\textbf{d})$ denote the maximum degree in $\textbf{d}$. Our coupling result is optimal when $\Delta (\textbf{d})^2\ll \|\textbf{d}\|_1$, that is, $W_{ij}$ is asymptotic to ${\mathbb P}(ij\in{\mathcal G}(n,\textbf{d}))$ for every $i,j\in [n]$. We also have coupling results for $\textbf{d}$ that are not constrained by the condition $\Delta (\textbf{d})^2\ll \|\textbf{d}\|_1$. For such $\textbf{d}$ our coupling result is still close to optimal, in the sense that $W_{ij}$ is asymptotic to ${\mathbb P}(ij\in{\mathcal G}(n,\textbf{d}))$ for most pairs $ij\in \binom{[n]}{2}$.
We investigated cross-sectional and longitudinal associations between neonate microbial exposure and emerging behavioral temperament measures at the ages of 1, 2, and 3 years. Infants and mothers (n = 335) were extracted from the Kuopio Birth Cohort Study. Temperament was assessed using the Infant Behavioral and Early Childhood Behavioral Questionnaires. Microbial samples were collected from oral cavity at birth and the bacterial profiles were assessed using 16S rRNA gene sequencing. Microbial diversity was characterized using alpha and beta diversity metrics. Analyses were performed for the most abundant genera. The sample was analyzed as a whole, as well as divided into subgroups representing no antibiotic use during birth (n = 198) and those with antibiotic use during birth (n = 137). No significant associations were observed between microbial profiles and behavioral measures after Bonferroni corrections. Nevertheless, our pre-correction results indicated an association between increased behavioral temperament surgency in the first year and beta diversity (high abundance of Bacteroides, Faecalibacterium and Blautia, low abundance of Lactobacillus) in the antibiotic use group. Additionally, pre-corrections, a high relative abundance of Staphylococcus was associated with increased surgency through years 1, 2, and 3 in the no antibiotics group, prompting consideration into a possible link between antibiotic use and emerging behavioral temperament.
A 3D-printed polarization-independent low-cost lightweight and flexible frequency selective surface based dual-band microwave absorber is presented in this paper. Two concentric square loops fabricated at different heights using 3D printing technology are responsible for exhibiting dual-band responses at 3.32 GHz (S-band) and 5.46 GHz (C-band) with more than 97% absorptivities. The corresponding full widths at half maximum bandwidths are observed as 230 MHz (3.21–3.44 GHz) and 450 MHz (5.27–5.72 GHz). The proposed topology is polarization-insensitive owing to the four-fold symmetry. The absorption phenomenon is explained with the analysis of current distributions at the surface and impedance curves at the frequencies of resonance. Further, the performance has been evaluated for both planar and curved surfaces with different angles of curvature, and the good agreement between the measured and simulated responses confirms the flexible behavior of the proposed structure.
The present work focuses on a specific bouncing behaviour as a spherical particle settles through a density interface in the absence of a neutral buoyant position. This behaviour was initially discovered by Abaid et al. (Phys. Fluids, vol. 16, issue 5, 2004, pp. 1567–1580) in salinity-induced stratification. Both experimental and numerical investigations are conducted to understand this phenomenon. In our experiments, we employ particle image velocimetry (PIV) to measure the velocity distribution around the particle and to capture the transient wake structure. Our findings reveal that the bouncing process begins after the wake detaches from the particle. The PIV results indicate that an upward jet forms at the central axis behind the particle following wake detachment. By performing a force decomposition procedure, we quantify the contributions from the buoyancy of the wake ($F_{sb}$) and the flow structure ($F_{sj}$) to the enhanced drag. It is observed that $F_{sb}$ contributes primarily to the enhanced drag at the early stage, whereas $F_{sj}$ plays a critical role in reversing the particle's motion. Furthermore, our results indicate that the jet is a necessary condition for the occurrence of the bouncing motion. We also explore the minimum velocities (where negative values denote the occurrence of bouncing) of the particle, while varying the lower Reynolds number $Re_l$, the Froude number $Fr$, and the upper Reynolds number $Re_u$, within the ranges $1 \leqslant Re_l\leqslant 125$, $115 \leqslant Re_u\leqslant 356$ and $2 \leqslant Fr\leqslant 7$. Our findings suggest that the bouncing behaviour is influenced primarily by $Re_l$. Specifically, we observe that the bouncing motion occurs below a critical lower Reynolds number $Re^\ast _{l}=30$ in our experiments. In the numerical simulations, the highest value for this critical number is $Re^\ast _{l}=46.2$, which is limited to the parametric ranges studied in this work.
Soft wheat (Triticum aestivum L.) improvement could be enhanced by the identification of germplasm with superior end-use quality traits. Due to the geographic and historical separation of eastern and western US soft wheat germplasm ‘pools’, genetic differences in end-use quality may exist among cultivars arising from these two pools. To identify such differences, 30 US soft wheat cultivars were evaluated in ‘head-to-head’ trials over 3 years in Washington state. Cultivars were classified as: eastern soft red winter (SRW), eastern soft white winter (ESWW), western soft white (WSWW) and western Club. These four soft wheat cultivar classifications clearly differed systematically for some of the quality traits examined. The Club wheat cultivar group had the highest flour yield and flour ash. The Club group also had the lowest mixograph dough water absorption. Milling score (which incorporates break flour yield) was highest for Club and ESWW. Eastern soft red and white wheat cultivar groups had lower flour ash and alkaline water retention capacity (AWRC) compared to the western Club and soft white wheats; ESWW had the lowest AWRC of any classification. Cookie diameter was greatest for the ESWW group, followed by the SRW and Club groups (which were not significantly different), and then by the WSWW group. Individual cultivars with exceptional quality traits were also identified. These results indicate that the four US soft wheat germplasm pools differ, and they may be valuable genetic resources for ‘inter-pool’ wheat improvement.
New drugs to target different pathways in pulmonary hypertension has resulted in increased combination therapy, but details of this use in infants are not well described. In this large multicenter database study, we describe the pharmacoepidemiology of combination pulmonary vasodilator therapy in critically ill infants.
Methods:
We identified inborn infants discharged home from a Pediatrix neonatal ICU from 1997 to 2020 exposed to inhaled nitric oxide, sildenafil, epoprostenol, or bosentan for greater than two consecutive days. We compared clinical variables and drug utilisation between infants receiving simultaneous combination and monotherapy. We reported each combination’s frequency, timing, and duration and graphically represented drug use over time.
Results:
Of the 7681 infants that met inclusion criteria, 664 (9%) received combination therapy. These infants had a lower median gestational age and birth weight, were more likely to have cardiac and pulmonary anomalies, receive cardiorespiratory support, and had higher in-hospital mortality than those receiving monotherapy. Inhaled nitric oxide and sildenafil were most frequently used, and utilisation of combination and monotherapy for all drugs increased over time. Inhaled nitric oxide and epoprostenol were used in infants with a higher gestational age, earlier postnatal age, and shorter duration than sildenafil and bosentan. Dual therapy with inhaled nitric oxide and sildenafil was the most common combination therapy.
Conclusion:
Our study revealed an increased use of combination pulmonary vasodilator therapy, favouring inhaled nitric oxide and sildenafil, yet with considerable practice variation. Further research is needed to determine the optimal combination, sequence, dosing, and disease-specific indications for combination therapy.
Awareness of agricultural climate impacts is growing. In the European Union (EU), the agricultural sector is responsible for significant greenhouse gas emissions while continuing to receive considerable EU budgetary support. A large share of agricultural emissions is linked to livestock husbandry, a sector the direct and indirect climate impacts of which the EU's ‘green’ agricultural policies have historically ignored. This blind spot extends to the sizeable global deforestation footprint from EU livestock feed imports that remains unaddressed, despite the EU's aspired status as a global climate leader and major global agricultural market player. This article benchmarks the evolution of EU agri-climate legal and policy developments, using livestock emissions as a case study to highlight the importance of learning from the successes and failures of the EU experience, to realize future attempts to tackle global agricultural emissions.