To save content items to your account,
please confirm that you agree to abide by our usage policies.
If this is the first time you use this feature, you will be asked to authorise Cambridge Core to connect with your account.
Find out more about saving content to .
To save content items to your Kindle, first ensure no-reply@cambridge.org
is added to your Approved Personal Document E-mail List under your Personal Document Settings
on the Manage Your Content and Devices page of your Amazon account. Then enter the ‘name’ part
of your Kindle email address below.
Find out more about saving to your Kindle.
Note you can select to save to either the @free.kindle.com or @kindle.com variations.
‘@free.kindle.com’ emails are free but can only be saved to your device when it is connected to wi-fi.
‘@kindle.com’ emails can be delivered even when you are not connected to wi-fi, but note that service fees apply.
Gorerite, ideally CaAlFe11O19 is a new mineral and M-type hexaferrite of the magnetoplumbite group. It was found in ferrite-rich segregations of esseneite–gehlenite–wollastonite–anorthite melted rock of the ‘olive’ subunit of pyrometamorphic rocks located near Hatrurim Junction in the Negev Desert, Israel. Within these ferrite-rich segregations up to 100 μm in size, platy crystals of gorerite up to 50 μm in size intergrow with hibonite, hematite, maghemite, magnesioferrite, dorrite, barioferrite and andradite, forming aggregates. Additionally, small crystals of gorerite occur within magnesioferrite. Importantly, gorerite did not crystallise directly from the melt. Instead, it emerged through a reaction involving earlier crystallised hibonite and an iron-enriched melt, resulting in the partial or complete replacement of hibonite by gorerite. Gorerite appears grey in the reflected light (R = 18–23%), displaying distinct bireflectance: dark-grey perpendicular to Z and light-grey parallel to Z. Its Raman spectrum exhibits only one strong band at 700 cm–1, which shifts to higher frequencies with increasing Al content. Gorerite crystallises in the P63/mmc space group, with lattice parameters a = 5.8532(4) Å, c = 22.7730(2) Å and V = 675.67(7) Å3 with Z = 2. It exhibits a structure characterised by an intercalation of triple spinel-like S blocks and rock-salt type R blocks along the hexagonal c-axis.
As part of a parasitological survey, several specimens of two new monopisthocotylean species, Neotetraonchus celsomanueli sp. nov. and N.peruvianus sp. nov. (Dactylogyridea, Dactylogyridae), were collected from the gill filaments of the Peruvian sea catfish Galeichthys peruvianus (Siluriformes, Ariidae) off Puerto Pizarro, Tumbes region, Peru. Neotetraonchus celsomanueli sp. nov. is characterised by an MCO with a T-shaped distal end and an accessory piece that is ribbed and expanded proximally with a worm-shaped termination. Neotetraonchus peruvianus sp. nov. is typified by its MCO, which has a sledgehammer-shaped distal end and an accessory piece with a claw-shaped distal end. Additionally, N.peruvianus sp. nov. is characterised by its jellyfish-shaped onchium. A partial 28S rDNA sequence was obtained from N.celsomanueli sp. nov., and a phylogenetic analysis was conducted. This analysis revealed the phylogenetic position of Neotetraonchus celsomanueli sp. nov. within a clade comprising monopisthocotylean parasites of diadromous and marine ariid catfishes, including Hamatopeduncularia spp., Chauhanellus spp., Thysanotohaptor Kritsky, Shameem, Kumari & Krishnaveni, 2012, and Neocalceostomoides spinivaginalis Lim, 1995. This finding brings the number of known Neotetraonchus species to seven and represents the first described Neotetraonchus species infecting marine catfishes from Peru.
In this Reply to Critics, I respond to essays by Professors Alysia Blackham, Jessica Eisen, Pablo Gilabert, Andrea Sangiovanni, Dale Smith, Iyiola Solanke, and Daniel Viehoff on the theory of wrongful discrimination developed in my book, Faces of Inequality. Among the topics I discuss are: the relationship between equality and discrimination, the role of social subordination in my theory of wrongful discrimination, and methodology in discrimination theory.
In Faces of Inequality, Sophia Moreau offers a pluralist theory of discrimination, according to which discriminatory conduct involves one or more of (at least) three types of wrong. She claims, further, that each of these wrongs represents a failure to treat some people as the equal of others. I argue that this further claim is mistaken. I also suggest that there may be no need for a pluralist theory of discrimination to identify a property that is shared by the different types of wrong recognised by the theory (beyond the fact that each is present in cases of wrongful discrimination).
Transoral robotic surgery total laryngectomy is a promising procedure. We conducted a systematic review to study the indications, surgical techniques and complications of this procedure.
Methods
We followed the guidelines outlined in the Preferred Reporting Items for Systematic Reviews and Meta-Analysis statement.
Results
We concluded with 5 studies and 27 surgeries. The main indications of transoral robotic surgery total laryngectomy were selected recurrent laryngeal squamous cell carcinomas, dysfunctional larynx, and specific primary non-squamous cell carcinoma laryngeal cancers. The rate of pharyngocutaneous fistula was 20 per cent overall. In every reported cancer case, the specimen was excised within negative surgical margins. The average time of the procedure was 282.6 minutes.
Conclusion
Transoral robotic surgery total laryngectomy is a safe procedure of high value. The preservation of strap muscles and hyoid bone as well as the sacrifice of less mucosa compared to the traditional technique reduces the risk of certain complications and improves the swallowing outcome.
The concept of a forest transition – a regional shift from deforestation to forest recovery – tends to equate forest area expansion with sustainability, assuming that more forest is good for people and the environment. To promote debate and more just and ecologically sustainable outcomes during this period of intense focus on forests (such as the United Nations’ Decade on Ecological Restoration, the Trillion Trees initiative and at the United Nations’ Climate Change Conferences), we synthesize recent nuanced and integrated research to inform forest management and restoration in the future. Our results reveal nine pitfalls to assuming forest transitions and sustainability are automatically linked. The pitfalls are as follows: (1) fixating on forest quantity instead of quality; (2) masking local diversity with large-scale trends; (3) expecting U-shaped temporal trends of forest change; (4) failing to account for irreversibility; (5) framing categories and concepts as universal/neutral; (6) diverting attention from the simplification of forestlands into single-purpose conservation forests or intensive production lands; (7) neglecting social power transitions and dispossessions; (8) neglecting productivism as the hidden driving force; and (9) ignoring local agency and sentiments. We develop and illustrate these pitfalls with local- and national-level evidence from Southeast Asia and outline forward-looking recommendations for research and policy to address them. Forest transition research that neglects these pitfalls risks legitimizing unsustainable and unjust policies and programmes of forest restoration or tree planting.
In this introduction, I briefly summarize Sophia Moreau's Faces of Inequality. I situate her monograph within two highly contemporary bodies of literature — relational egalitarianism and discrimination theory — to show how it provides important insights for understanding both what it means to treat others as equals in society and how to define wrongful discrimination. Moreau's work on discrimination is of great relevance for philosophers and socio-legal theorists alike as the commentaries from the symposium contributors demonstrate, including Dale Smith, Pablo Gilabert, Andrea Sangiovanni, Daniel Viehoff, Jessica Eisen, Alysia Blackham, and Iyiola Solanke.
Oscillatory flows have become an indispensable tool in microfluidics, inducing inertial effects for displacing and manipulating fluid-borne objects in a reliable, controllable and label-free fashion. However, the quantitative description of such effects has been confined to limit cases and specialized scenarios. Here we develop an analytical formalism yielding the equation of motion of density-mismatched spherical particles in oscillatory background flows, generalizing previous work. Inertial force terms are systematically derived from the geometry of the flow field together with analytically known Stokes number dependences. Supported by independent, first-principles direct numerical simulations, we find that these forces are important even for nearly density-matched objects such as cells or bacteria, enabling their fast displacement and separation. Our formalism thus consistently incorporates particle inertia into the Maxey–Riley equation, and in doing so provides a generalization of Auton's modification to added mass, as well as recovering the description of acoustic radiation forces on particles as a limiting case.
The war in Ukraine raises concerns for potential hazards of radiological and nuclear incidents. Children are particularly vulnerable in these incidents and may need pharmaceutical countermeasures, including antidotes and cytokines. Searches found no published study comparing pediatric indications and dosing among standard references detailing pediatric medications for these incidents. This study addresses this gap by collecting, tabulating, and disseminating this information to healthcare professionals caring for children. Expert consensus chose the following references to compare their pediatric indications and dosing of medical countermeasures for radiation exposure and internal contamination with radioactive materials: Advanced Hazmat Life Support (AHLS) for Radiological Incidents and Terrorism, DailyMed, Internal Contamination Clinical Reference, Medical Aspects of Radiation Incidents, and Medical Management of Radiological Casualties, as well as Micromedex, POISINDEX, and Radiation Emergency Medical Management (REMM). This is the first study comparing pediatric indications and dosing for medical countermeasures among commonly used references for radiological and nuclear incidents.
Cette étude se penche sur la communication du Parti conservateur du Québec (PCQ) sur Facebook et X au cours de l'année précédant l’élection générale québécoise de 2022. Basée sur une analyse de contenu d'un échantillon de 800 messages diffusés sur Facebook et X par le parti et son chef Éric Duhaime, l'analyse relève les éléments populistes des publications de même que les objectifs politiques de sa communication en ligne. L'article démontre comment le parti a utilisé ces plateformes numériques afin de tenter de mobiliser une base d’électeurs en contournant les filtres médiatiques traditionnels et en s'adressant directement aux électeurs afin de tirer profit du contexte médiatique hybride québécois. Deux conclusions découlent de nos analyses. Premièrement, le PCQ semble avoir employé un discours populiste à caractère antiélitiste de manière à exploiter une grogne pandémique présente au Québec. Deuxièmement, le parti a utilisé les fonctions de mobilisations qu'offrent les médias socionumériques afin de constituer une coalition d’électeurs.
A significant proportion of people with clozapine-treated schizophrenia develop ‘checking’ compulsions, a phenomenon yet to be understood.
Aims
To use habit formation models developed in cognitive neuroscience to investigate the dynamic interplay between psychosis, clozapine dose and obsessive–compulsive symptoms (OCS).
Method
Using the anonymised electronic records of a cohort of clozapine-treated patients, including longitudinal assessments of OCS and psychosis, we performed longitudinal multi-level mediation and multi-level moderation analyses to explore associations of psychosis with obsessiveness and excessive checking. Classic bivariate correlation tests were used to assess clozapine load and checking compulsions. The influence of specific genetic variants was tested in a subsample.
Results
A total of 196 clozapine-treated individuals and 459 face-to-face assessments were included. We found significant OCS to be common (37.9%), with checking being the most prevalent symptom. In mediation models, psychosis severity mediated checking behaviour indirectly by inducing obsessions (r = 0.07, 95% CI 0.04–0.09; P < 0.001). No direct effect of psychosis on checking was identified (r = −0.28, 95% CI −0.09 to 0.03; P = 0.340). After psychosis remission (n = 65), checking compulsions correlated with both clozapine plasma levels (r = 0.35; P = 0.004) and dose (r = 0.38; P = 0.002). None of the glutamatergic and serotonergic genetic variants were found to moderate the effect of psychosis on obsession and compulsion (SLC6A4, SLC1A1 and HTR2C) survived the multiple comparisons correction.
Conclusions
We elucidated different phases of the complex interplay of psychosis and compulsions, which may inform clinicians’ therapeutic decisions.
We extend the resolvent framework to two-phase flows with low-inertia particles. The particle velocities are modelled using the equilibrium Eulerian model. We analyse the turbulent flow in a vertical pipe with Reynolds number of $5300$ (based on diameter and bulk velocity), for Stokes numbers $St^+=0-1$, Froude numbers $Fr_z=-4,-0.4,0.4,4$ and $1/Fr_z = 0$ (gravity omitted). The governing equations are written in input–output form and a singular value decomposition is performed on the resolvent operator. As for single-phase flows, the operator is low rank around the critical layer, and the true response can be approximated using one singular vector. Even with a crude forcing model, the formulation can predict physical phenomena observed in Lagrangian simulations, such as particle clustering and gravitational effects. Increasing the Stokes number shifts the predicted concentration spectra to lower wavelengths; this shift also appears in the direct numerical simulation spectra and is due to particle clustering. When gravity is present, there are two critical layers, one for the concentration field, and one for the velocity field. For upward flow, the peak of concentration fluctuations shifts closer to the wall, in agreement with the literature. We explain this with the aid of the different locations of the two critical layers. Finally, the model correctly predicts the interaction of near-wall vortices with particle clusters. Overall, the resolvent operator provides a useful framework to explain and interpret many features observed in Lagrangian simulations. The application of the resolvent framework to higher $St^+$ flows in combination with Lagrangian simulations is also discussed.