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Evidence suggests that cognitive behavioural therapy (CBT) can be a helpful approach for older adults experiencing anxiety and depression. Some research has suggested this is also the case for those caring for a family member with dementia. Little research has been conducted into the impact of CBT for older adults juggling the demands of caring for multiple family members with dementia.
Aims:
This case study aimed to evaluate the application of CBT to ‘Mrs P’, a 68-year-old client experiencing anxiety and depression whilst caring for two family members with dementia.
Method:
A single case experimental design study was conducted to assess the effectiveness of CBT formulation and intervention, including cognitive restructuring of unhelpful thoughts about caregiving and increasing engagement in pleasurable activities.
Results:
Mrs P’s depression and anxiety scores improved significantly throughout treatment, and she met her goal of being able to manage when caregiving activities go wrong during daily life.
Conclusions:
CBT may be a helpful approach to reducing anxiety and depression in dementia family caregivers.
The field of research related to CO2 capture is significant and really attractive for sustainable green chemistry. Focusing attention on this topic in our research led to obtaining new compounds based on diamines. As a result of the syntheses carried out using aqueous solutions of diamines exposed to the slow action of carbon dioxide from the air, three new monocarbamates were obtained. X-ray powder diffraction data for the obtained compounds: 12-propCO2 (C4H10N2O2) [a = 9.3033(7), b = 9.2485(7), c = 7.4735(7) Å, β = 111.214(7)°, V = 599.46 Å3, Z = 4, space group Ia]; 13-propCO2 (C4H10N2O2) [a = 5.0065(10), b = 12.2093(23), c = 4.9006(10) Å, β = 96.457(18)°, V = 297.65 Å3, Z = 2, space group P21]; and 13-dytekCO2 (C6H14N2O2) [a = 28.374(3), c = 5.1726(9) Å, V = 3606.53 Å3, Z = 18, space group $R\bar{3}$] are reported in this paper.
To establish outcomes following photobiomodulation therapy for tinnitus in humans and animal studies.
Methods
A systematic review and narrative synthesis was conducted in accordance with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses statement. The databases searched were: Medline, Embase, Cochrane Central Register of Controlled Trials (‘Central’), ClinicalTrials.gov and Web of Science including the Web of Science Core collection. There were no limits on language or year of publication.
Results
The searches identified 194 abstracts and 61 full texts. Twenty-eight studies met the inclusion criteria, reporting outcomes in 1483 humans (26 studies) and 34 animals (2 studies). Photobiomodulation therapy parameters included 10 different wavelengths, and duration ranged from 9 seconds to 30 minutes per session. Follow up ranged from 7 days to 6 months.
Conclusion
Tinnitus outcomes following photobiomodulation therapy are generally positive and superior to no photobiomodulation therapy; however, evidence of long-term therapeutic benefit is deficient. Photobiomodulation therapy enables concentrated, focused delivery of light therapy to the inner ear through a non-invasive manner, with minimal side effects.
In this article, we explore the status of Samaritans in early modern Ottoman Damascus through a focus on a particular firman—a sultanic legal decree. The firman orders that Samaritans—a religious group that traces its origins to ancient Israel but differs from Jews in several aspects—are not to be employed as clerks by Ottoman authorities. We argue that the firman indicates Ottoman officials engaged in religious status management despite the lack of legal terminology for minority in the document. The significance of the firman regarding conceptualizing status, we suggest, is that it points to an alternative model of minoritization that is not based in modern European legal approaches to religious minority status and law but which accounts for people’s experiences of minority status before modernity.
This paper presents some of the first results of global linear stability analyses performed using a bespoke eigensolver that has recently been implemented in the next generation flow solver framework CODA. The eigensolver benefits from the automatic differentiation capability of CODA that allows computation of the exact product of the Jacobian matrix with an arbitrary complex vector. It implements the Krylov–Schur algorithm for solving the eigenvalue problem. The bespoke tool has been validated for the case of laminar flow past a circular cylinder with numerical results computed using the TAU code and those reported in the literature. It has been applied with both second-order finite volume and high-order discontinuous Galerkin schemes for the case of laminar flow past a square cylinder. It has been demonstrated that using high-order schemes on coarser grids leads to well-converged eigenmodes with a shorter computation time compared to using second-order schemes on finer grids.
This article presents results of a Dutch randomised experiment, challenging the ‘workfare’ paradigm, which is dominant in many countries. We study whether social assistance (SA) schemes with fewer conditions and more autonomy for recipients stimulate valuable but often overlooked unpaid socio-economic activities (USEA), which are not classified as work. In the qualitative part of the mixed method study, we generated new hypotheses stating that particularly recipients who are older, higher educated, have a migration background, have relatively poor health, or have young children, will spend more time on USEA in less conditional and more autonomous regimes. The quantitative part of the study, where two experimental conditions are compared with the usual treatment of SA recipients, does not show convincing average treatment effects, but does reveal that a less conditional and more autonomy-oriented SA scheme translates into more USEA for older people, people with a migration background and people with relatively poor mental health.
This paper studies the relationship between slack and research and development (R&D) investment by addressing the role of the founder as the ‘microfoundation’ among Chinese newly listed firms. We propose a contingent approach to understanding the slack-R&D investment relationship by examining the influence of the founder’s human capital and social ties, which is distinguished into political and managerial ties. Our results show that the founder’s human capital, measured by its educational level, strengthens the relationship between absorbed and unabsorbed slack resources and R&D investment. We also find that the founder’s managerial ties strengthen the relationship between resource slack and R&D intensity, whereas political ties weaken that link. Our results demonstrate the founder’s crucial role in underpinning resource utilization in newly listed firms and emphasise the importance of social ties in driving firms’ R&D activities in emerging economies.
We construct an existentially undecidable complete discretely valued field of mixed characteristic with existentially decidable residue field and decidable algebraic part, answering a question by Anscombe–Fehm in a strong way. Along the way, we construct an existentially decidable field of positive characteristic with an existentially undecidable finite extension, modifying a construction due to Kesavan Thanagopal.
Despite the importance of timing of nerve surgery after peripheral nerve injury, optimal timing of intervention has not been clearly delineated. The goal of this study is to explore factors that may have a significant impact on clinical outcomes of severe peripheral nerve injury that requires reconstruction with nerve transfer or graft.
Materials and Methods:
Adult patients who underwent peripheral nerve transfer or grafting in Alberta were reviewed. Clustered multivariable logistic regression analysis was used to examine the association of time to surgery, type of nerve repair, and patient characteristics on strength outcomes. Cox proportional hazard regression analysis model was used to examine factors correlated with increased time to surgery.
Results:
Of the 163 patients identified, the median time to surgery was 212 days. For every week of delay, the adjusted odds of achieving Medical Research Council strength grade ≥ 3 decreases by 3%. An increase in preinjury comorbidities was associated with longer overall time to surgery (aHR 0.84, 95% CI 0.74–0.95). Referrals made by surgeons were associated with a shorter time to surgery compared to general practitioners (aHR 1.87, 95% CI 1.14–3.06). In patients treated with nerve transfer, the adjusted odds of achieving antigravity strength was 388% compared to nerve grafting; while the adjusted odds decreased by 65% if the injury sustained had a pre-ganglionic injury component.
Conclusion:
Mitigating delays in surgical intervention is crucial to optimizing outcomes. The nature of initial nerve injury and surgical reconstructive techniques are additional important factors that impact postoperative outcomes.
Sorghum (Sorghum bicolor (L.) Moench) is a dual nature crop, which is used for food as well as fodder, depending on plant ideotype. Sorghum forage is important for ruminants, but a major constraint is the anti-nutritional factor dhurrin, a hydrocyanic acid (HCN) producing glucoside. There are several additional effects of dhurrin, which reduce the nutritional value of sorghum fodder for livestock. This two-year study was aimed to evaluate the variation among diverse sorghum varieties, specifically for HCN content, forage yield and stem sugar content (brix value) under arid climate in Pakistan. Nine sorghum varieties were used for this experiment: JS-2002, Chakwal sorghum, Lines CS-17, Super late, PAK SS-2, Johar, JS-263, Sargodha-2011 and YSS-98. Results reveal that Sargodha-2011 had superior morphological traits for fresh forage and dry biomass yield, and stem brix value, compared to other varieties. Higher HCN contents were recorded in Super late compared to other varieties. Significant negative correlation of HCN with yield showed that improvement in yield will reduce the HCN content of sorghum. In conclusion, sorghum variety SGD-11 was shown best performing for higher biomass yield and brix value, and lower HCN content compared to other tested varieties under arid climate of Thal, Pakistan.
Social connections have a significant impact on health across age groups, including older adults. Loneliness and social isolation are known risk factors for Alzheimer’s disease and related dementias (ADRD). Yet, we did not find a review focused on meta-analyses and systematic reviews of studies that had examined associations of social connections with cognitive decline and trials of technology-based and other social interventions to enhance social connections in people with ADRD.
Study design:
We conducted a scoping review of 11 meta-analyses and systematic reviews of social connections as possible determinants of cognitive decline in older adults with or at risk of developing ADRD. We also examined eight systematic reviews of technology-based and other social interventions in persons with ADRD.
Study results:
The strongest evidence for an association of social connections with lower risk of cognitive decline was related to social engagement and social activities. There was also evidence linking social network size to cognitive function or cognitive decline, but it was not consistently significant. A number of, though not all, studies reported a significant association of marital status with risk of ADRD. Surprisingly, evidence showing that social support reduces the risk of ADRD was weak. To varying degrees, technology-based and other social interventions designed to reduce loneliness in people with ADRD improved social connections and activities as well as quality of life but had no significant impact on cognition. We discuss strengths and limitations of the studies included.
Conclusions:
Social engagement and social activities seem to be the most consistent components of social connections for improving cognitive health among individuals with or at risk for ADRD. Socially focused technology-based and other social interventions aid in improving social activities and connections and deserve more research.
This paper investigates nga-marked numerals in Albanian. They qualify as distributive numerals, since the presence of nga on the numeral yields a distributive reading of the sentences they belong to. Beyond their differences, most of the previous accounts rely on the hypothesis that distributive numerals introduce some kind of semantic feature, e.g. a covariation feature; an evaluation plurality requirement, also called a post-suppositional plurality requirement; or a distributivity force. Our main claim goes against this trend of thinking. We propose that distributive numerals do not carry any semantic feature but only a formal syntactic feature that needs to enter a syntactic dependency relation with a distributivity feature. The analysis is implemented in terms of Zeijlstra’s (2004) upward agree.
Reflecting the international experience, statistics show that most medical negligence cases in Ireland settle. Less is known, however, about the duration of these cases, though anecdotal evidence suggests that they are protracted in nature. Procedurally focused reforms, aimed at reducing costs and facilitating more expedient resolution of these disputes have been proposed in Ireland, yet await implementation. As such, the pace of litigation is largely determined by the parties to the dispute. Drawing on the findings of an empirical study (an analysis of closed case files and qualitative interviews), this article explores two questions: first, how long do medical negligence cases take to resolve; and secondly, what contributes to delay in this context. Whilst causes of delay may vary by case, it is important to attempt to identify and explore common factors which contribute to delay. If these factors can be problematised and understood, possible solutions may be reached. In doing so, the article contributes to the debate on medical negligence reform across common law jurisdictions, evidencing the broader considerations, in addition to procedurally focused reforms, which are required when considering the issue of delay.