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A new generation of implantable brain–computer interfaces (BCI) devices have been tested for the first time in a human clinical trial, with significant success. These intelligent implants detect specific neuronal activity patterns, such as an epileptic seizure, and provide information to help patients to respond to the upcoming neuronal events. By forecasting a seizure, the technology keeps patients in the decisional loop; the device gives control to patients on how to respond and decide on a therapeutic course ahead of time. Being kept in the decisional loop can positively increase patients’ quality of life; however, doing so does not come free of ethical concerns. There is currently a lack of evidence concerning the various impacts of closed-loop system BCIs on patients’ decisionmaking processes, especially how being in the decisional loop impacts patients’ sense of autonomy. This article addresses these gaps by providing data that we obtained from a first-in-human clinical trial involving patients implanted with advisory brain devices. This article explores ethical issues related to the risks involved in being kept in the decisional loop.
The lack of sleep is a significant problem in the modern world. The structure of the economy means that 24 hour working is required from some of us, sometimes because we are expected to be able to respond to share-price fluctuations on the other side of the planet, sometimes because we are expected to serve kebabs to people leaving nightclubs, and sometimes because lives depend on it. The immediate effect is that we feel groggy; but there may be much more sinister long-term effects of persistent sleep deprivation and disruption, the evidence for which is significant, and worth taking seriously. If sleeplessness has a serious impact on health, it represents a notable public health problem. In this article, I sketch that problem, and look at how exploiting the pharmacopoeia (or a possible future pharmacopoeia) might allow us to tackle it. I also suggest that using drugs to mitigate or militate against sleeplessness is potentially morally and politically fraught, with implications for social justice. Hence, whatever reasons we have to use drugs to deal with the problems of sleeplessness, we ought to be careful.
Meeting healthcare needs is a matter of social justice. Healthcare needs are virtually limitless; however, resources, such as money, for meeting those needs, are limited. How then should we (just and caring citizens and policymakers in such a society) decide which needs must be met as a matter of justice with those limited resources? One reasonable response would be that we should use cost effectiveness as our primary criterion for making those choices. This article argues instead that cost-effectiveness considerations must be constrained by considerations of healthcare justice. The goal of this article will be to provide a preliminary account of how we might distinguish just from unjust or insufficiently just applications of cost-effectiveness analysis to some healthcare rationing problems; specifically, problems related to extraordinarily expensive targeted cancer therapies. Unconstrained compassionate appeals for resources for the medically least well-off cancer patients will be neither just nor cost effective.
This paper offers an in-depth look at roots and verb stem morphology in Chuj (Mayan) in order to address a larger question: when it comes to the formation of verb stems, what information is contributed by the root, and what is contributed by the functional heads? I show first that roots in Chuj are not acategorical in the strict sense (cf. Borer 2005), but must be grouped into classes based on their stem-forming possibilities. Root class does not map directly to surface lexical category, but does determine which functional heads (i.e. valence morphology) may merge with the root. Second, I show that while the introduction of the external argument, along with clausal licensing and agreement generally, are all governed by higher functional heads, the presence or absence of an internal argument is dictated by the root. Specifically, I show that transitive roots in Chuj always combine with an internal argument, whether it be (i) a full DP, (ii) a bare pseudo-incorporated NP, or (iii) an implicit object in an antipassive. In the spirit of work such as Levinson (2007, 2014), I connect this to the semantic type of the root; root class reflects semantic type, and semantic type affects the root’s combinatorial properties. This work also contributes to the discussion of how valence morphology operates. In line with works such as Alexiadou, Anagnostopoulou & Schäfer (2006), I argue that valence morphology applies directly to roots, rather than to some ‘inherent valence’ of a verb.
In 1924, the British biologist J.B.S. Haldane acknowledged that anyone who tried to predict where science was taking us was obliged to mention H.G. Wells, since ‘[t]he very mention of the future suggests him’. Nevertheless, Haldane complained that Wells was ‘a generation behind the time’, having been raised when flying and radiotelegraphy were genuinely scientific questions, but they were now mere ‘commercial problems’, Haldane asserted, and ‘I believe that the centre of scientific interest lies in biology’. Haldane's conviction that biology was the key to the future was widely shared, and lies in the background of both these books. Helen Curry examines the early history of the dream of engineering new kinds of plants, using first X-rays, then colchicine (a chemical mutagen), and then the new sources of intense radioactivity that were created by the early nuclear reactors. By contrast, Ewa Luczak is interested in the influence of eugenics on American literature, focusing particularly on Jack London, Charlotte Perkins Gilman and George Schuyler. What unites these books (and the diverse topics they address) is new ways of imagining the future, specifically a future based in biology.
In this paper, I discuss the development and use of images employed by the Dresden Royal Museum for Zoology, Anthropology and Ethnography to resolve debates about how to use visual representation as a means of making ethnographic knowledge. Through experimentation with techniques of visual representation, the founding director, A.B. Meyer (1840–1911), proposed a historical, non-essentialist approach to understanding racial and cultural difference. Director Meyer's approach was inspired by the new knowledge he had gained through field research in Asia-Pacific as well as new forms of imaging that made highly detailed representations of objects possible. Through a combination of various techniques, he developed new visual methods that emphasized intimate familiarity with variations within any one ethnic group, from skull shape to material ornamentation, as integral to the new disciplines of physical and cultural anthropology. It is well known that photographs were a favoured form of visual documentation among the anthropological and ethnographic sciences at the fin de siècle. However, in the scholarly journals of the Dresden museum, photographs, drawings, tables and etchings were frequently displayed alongside one another. Meyer sought to train the reader's eye through organized arrangements that represented objects from multiple angles and at various levels of magnification. Focusing on chimpanzees, skulls and kettledrums from Asia-Pacific, I track the development of new modes of making and reading images, from zoology and physical anthropology to ethnography, to demonstrate how the museum visually historicized humankind.