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Secondary stroke prevention can reduce subsequent vascular events, mortality and accumulation of disability. Current rates of adherence to secondary stroke prevention indicators are unknown. Our aim was to evaluate secondary stroke prevention care in Ontario, Canada.
Methods:
A retrospective cohort study using health administrative databases included all adults discharged alive following an ischemic stroke from April 2010 to March 2019. Indicators of secondary stroke prevention, including laboratory testing, physician visits and receipt of routine influenza vaccinations, were evaluated among survivors in the one year following a stroke event. The use of medication was also assessed among individuals over the age of 65 years and within subgroups of stroke survivors with diabetes and atrial fibrillation.
Results:
After exclusions, 54,712 individuals (mean age 68.4 years, 45.7% female) survived at least one year following their stroke event. In the 90 days following discharge from the hospital, most individuals (92.8%) were seen by a general practitioner, while 26.2% visited an emergency department. Within the year following discharge, 66.2% and 61.4% were tested for low-density lipoprotein and glycated hemoglobin, respectively, and 39.6% received an influenza vaccine. Among those over the age of 65 years, 85.5% were prescribed a lipid-lowering agent, and 88.7% were prescribed at least one antihypertensive medication. In those with diabetes, 70.3% were prescribed an antihyperglycemic medication, while 84.9% with atrial fibrillation were prescribed an anticoagulant.
Conclusion:
Secondary stroke prevention, especially for important laboratory values, remains suboptimal, despite thorough best practice guidelines. Future studies should explore barriers to better secondary stroke care.
Increased rehabilitation intensity, the number of minutes of therapy per day, is associated with improved outcomes. However, it is unclear whether males and females receive the same inpatient stroke rehabilitation intensity. A sub-analysis of a retrospective population-based cohort study of adults (5877 females, 6893 males) with stroke discharged to inpatient rehabilitation between 2017 and 2021 was conducted. The mean rehabilitation intensity was 75.86 min/day for males and 73.33 min/day for females (p < .0001). Males <80 years of age were more likely to receive higher rehabilitation intensity than females. Future research should explore what factors account for this sex difference.
NICE guidelines recommend that patients started on antidepressants aged 18–25 years are reviewed 1 week after initiating treatment to check response. All other patients should be reviewed within 2 weeks. The audit aimed to evaluate if these guidelines are being met in Primary Care now that most mental health appointments have changed from face to face to telephone consultations post COVID-19.
Methods
Notes of 60 patients that had been started on an SSRI across the period of January 2022 – December 2022 at a North West based Primary Care practice were analysed. Time from initial consultation to medication review with a general practitioner (GP) and/or contact with a Mental Health Practitioner (MHP) within the practice were recorded. Consultation notes from MHPs were analysed for reference to tolerability of medication to assess if the patient's new treatment was discussed as part of support appointments.
Results
Median time for initial follow-up of patients aged 18–25 years was 3 weeks demonstrating 8% compliance with NICE guidelines. Median time for initial follow-up for those >25 was 4 weeks, demonstrating 19% compliance with NICE guidelines. Of those that did not receive a follow-up with a GP within the suggested time frame, 20% met with a MHP for support with their condition and had side effects of new medication referenced in the notes. Within 4 weeks, 58% of patients had an appointment with a MHP where medication was mentioned. Median follow-up for anxiety disorders was 4.5 weeks compared to disorders of depression at 4 weeks. Patients new to the SSRI were followed up at a median of 3 weeks compared to 4 weeks for those that had completed a course previously.
Conclusion
Current follow-up of patients at the practice is not compliant with NICE guidelines. A practice meeting will be held to identify improvements to the patient follow-up process and look at the barriers patients face when arranging follow-up appointments. More than half of audited patients met with a MHP for support within 4 weeks of SSRI initiation. This highlights an opportunity to assess patients that are already meeting with practice staff when GPs have been unable to review them within the time frame. A pro-forma will be developed for MHP to utilise to specifically ask about medication. A repeat audit of both GP and MHP appointments will be completed in 6 months.
By July 2021, we will increase the percentage of full recording of physical health data for 90% of patients
Methods
-Completion of recording (green results) was measured using Tableau Software for a 10 week period from Jan- March 2021 (baseline), then monthly during the study
• PDSA cycles were conducted between April and July 2021 with analysis and changes tested monthly as per PDSA methodology. This informed future interventions.
• We involved staff in designing a flowchart/protocol of how to book patients into the well-being clinic and sought opinions on how recordings could be improved.
Results
• In March, prior to any changes being implemented, staff were reminded to complete recording of physical health data. This improved percentage of recordings up to 62% by 1 st April.
• Following this, a training session about the well-being clinic was arranged for all EIS staff.
• A further session was arranged for staff to devise a flowchart of how the process will operate and generate further ideas.
• A reminder system was put in place with the team leader emailing care co-ordinators monthly.
• By 1 st July, percentage of complete recordings were 73%.
• We decided to continue with the project and to increase the frequency of reminders to fortnightly. This helped to improve the percentage of complete recordings to 90% by September 2021.
Conclusion
• We learnt that education and training amongst all staff was needed to improve the recording of physical health data.
• Improved utilisation of the physical health well-being clinic helped to streamline physical health assessments and helped to reduce the workload of EIS staff (also promotes sustainability).
• Involving staff in designing and implementing changes leads to better adherence in improving physical health recording.
• More time was needed for the interventions to be implemented in our service (target reached later than original timeframe), but this should now be sustainable.
• Reminder systems will need to continue to ensure that performance is maintained, with further training provided as required.
The North Carolina Legislature appropriated funds in 2016–2019 for the Healthy Food Small Retailer Program (HFSRP), providing small retailers located in food deserts with equipment to stock nutrient-dense foods and beverages. The study aimed to: (1) examine factors facilitating and constraining implementation of, and participation in, the HFSRP from the perspective of storeowners and (2) measure and evaluate the impact and effectiveness of investment in the HFSRP.
Design:
The current analysis uses both qualitative and quantitative assessments of storeowner perceptions and store outcomes, as well as two innovative measures of policy investment effectiveness. Qualitative semi-structured interviews and descriptive quantitative approaches, including monthly financial reports and activity forms, and end-of-programme evaluations were collected from participating HFSRP storeowners.
Setting:
Eight corner stores in North Carolina that participated in the two cohorts (2016–2018; 2017–2019) of the HFSRP.
Participants:
Owners of corner stores participating in the HFSRP.
Results:
All storeowners reported that the HFSRP benefitted their stores. In addition, the HFSRP had a positive impact on sales across each category of healthy food products. Storeowners reported that benefits would be enhanced with adjustments to programme administration and support. Specific suggestions included additional information regarding which healthy foods and beverages to stock; inventory management; handling of perishable produce; product display; modified reporting requirements and a more efficient process of delivering and maintaining equipment.
Conclusions:
All storeowners reported several benefits of the HFSRP and would recommend that other storeowners participate. The barriers and challenges they reported inform potential approaches to ensuring success and sustainability of the HFSRP and similar initiatives underway in other jurisdictions.
Introduction: Les erreurs médicales sont causées par des failles de système plutôt qu'un seul individu. Dans ce contexte, de multiples designs pédagogiques de formation interprofessionnelle (FIP) ont été proposés pour développer une meilleure collaboration interprofessionnelle. L'une des initiatives pédagogiques proposées en médecine de désastre est la simulation de table (TTX). La TTX consiste à simuler une situation de code orange dans un environnement informel où les participants doivent discuter de la suite logique des actions à prendre. Le protocole d'arrêt cardiaque intra-hospitalier chez le nourrisson de moins de 30 jours (code rose) ayant été mis à jour au Centre hospitalier de l'Université de Montréal (CHUM), cela a généré un besoin de FIP au sein des équipes. Ainsi, nous avons développé une FIP innovante en utilisant la TTX pour enseigner un nouveau protocole de code rose. L'objectif primaire de la présente étude est d'évaluer la perception des apprenants à propos de cette FIP. Methods: La présente étude rétrospective de cohorte s'est déroulée en mars 2019 au centre de simulation du Centre hospitalier de l'Université de Montréal. Un groupe interprofessionnel (médecins, infirmières, inhalothérapeutes, préposés aux bénéficiaires, etc.) a été recruté. Un sondage de satisfaction des participants leur a été remis immédiatement après la TTX. Des statistiques descriptives (n, %) ont été réalisées. Les commentaires recueillis lors du débreffage ont permis de nuancer les résultats et d'apporter des changements à la nouvelle procédure de code rose. Results: Un total de 13 participants ont participé à la TTX, dont 10 ont répondu au sondage (10/13 : 77%). 3 observateurs ont participé à la TTX et ont tous répondu à certaines questions du sondage (3/3 : 100%). Suite à la TTX, 80% (n = 8) des participants ont eu l'impression de mieux comprendre leur propre rôle et 90% (n = 9) des participants ont eu l'impression de mieux comprendre le rôle des autres professionnels. Tous (100%, n = 13) ont apprécié la TTX et ont affirmé qu'il était probable ou très probable qu'ils participent à nouveau à une telle activité de FIP s'ils y étaient invités et qu'ils recommanderaient à un collègue d'y participer. Conclusion: Il est possible de réaliser une TTX pour une autre procédure d'urgence que le code orange, c'est-à-dire pour le code rose et cela est apprécié des participants. Ces derniers se sont sentis plus confiants dans leur rôle et dans leur connaissance du rôle des autres professionnels.
Introduction: Drones are already being used in medicine. They are employed to transport blood products and laboratory samples in rural and remote areas and they are increasingly being tested to deliver external defibrillators outside the hospital to patients with cardiac arrest. As this technology rapidly develops and attracts the attention of the scientific community, we present a rapid systematic review protocol that aims to synthesize the scientific evidence that has tested the use of drones to provide emergency medical care. Methods: A search strategy incorporating the concepts of ‘drone’ and ‘emergency medicine’ was launched in 52 bibliographic databases, including CINAHL and PubMed. Using the artificial intelligence module included in DistillerSR, a reviewer completed the first screening phase by reading the title and abstract of the retrieved articles. To be included, articles had to report empirical research projects that tested the potential uses of drones to improve the quality and accessibility of emergency medical care. These selection criteria were applied to the full text of the included articles during the second screening phase by a single reviewer. The results of these two screening phases will be validated by a second independent reviewer. The bibliography of included studies, relevant scientific journals and literature reviews will be manually searched for relevant articles. Results: The search strategy retrieved 1809 articles, of which 22 met our inclusion criteria in the first and second screening phases. Of these, one study used an empirical research design (qualitative interviews) to evaluate the usefulness of drones in emergency medicine, 17 used simulations or scenarios, and four were comprehensive literature reviews on the use of drones to provide healthcare. The final review will synthesize evidence related to the use of drones in emergency medicine and its impact on emergency medical services: nature of the emergency situation (cardiac arrest, blood transfusion), type of drone (fixed wing, quadcopter), tasks performed by drones (transport, surveillance), improvement in access or quality of care (patient's health, time saved in providing services). Conclusion: Drone technology is evolving rapidly and the indications for its use in providing emergency care is increasing. This rapid systematic review will focus on scientific studies aimed at testing the effectiveness of drones to improve the quality and access to emergency medical care.
The sorption of boron by clay minerals from natural waters has been studied experimentally. The quantity of boron sorbed per unit weight of clay mineral is dependent on both the salinity and the boron content of the solution. Previous work has shown that illite is the best clay mineral sorbent, though kaolinite and montmorillonite do sorb some boron and this is confirmed by the present work. The new experimental results demonstrate that the amount of boron sorbed by illite is not affected by the original boron content of the mineral and suggest that the process of incorporation of boron into the lattice proceeds in two stages. The bearing of these experimental results on the use of boron as a palaeosalinity indicator in sedimentary rocks is discussed and this leads to the conclusion that the rate of sedimentation may also influence the boron content of such rocks.
The electron microscope has been used to study the mechanisms of thermal decomposition of kaolinite in the temperature range 800-1350°C. Three main reaction mechanisms appear to be important in this temperature range. At 850°C metakaolinite breaks down to produce an amorphous defect oxide phase which is homogeneous and finely porous. When heated at 900°C the reaction product is a defect spinel with strongly preferred orientation and microporous structure. This defect spinel phase is observed in the temperature range 900-1150°C and shows little change in microstructure throughout this temperature range where the secondary development of muUite also occurs to a limited extent. Above 1150°C mullite develops in quantity and appears to represent the bulk of the reaction product at 1200°C.
A series of titanium silicate glasses along the composition joins TiO2-SiO2, TiO2-Na2SiO3, TiO2-K2SiO3 and TiO2-CaSiO3, has been examined using oxygen K-edge X-ray absorption near edge structure spectroscopy (XANES) confined to the near-surface region. Sharp pre-edge features in the spectra can be used to determine the Ti coordination in the glasses. The presence of [4]Ti is indicated by a pre-edge peak at ∼534 eV while [5]Ti is indicated by a peak at ∼533 eV. Titanium exists in all these glasses as [4]Ti and [5]Ti with no [6]Ti being present. For alkali-containing glasses the [5]Ti site becomes more prevalent with increasing TiO2. TiO2-K2SiO3 compositions contain a greater proportion of [4]Ti than comparable Na2O compositions. This is consistent with earlier Ti L-edge findings. The TEY spectra for the TiO2-CaSiO3 compositions indicate the presence of significant amounts of [5]Ti at high TiO2 contents; however, comparison of TEY (near surface) and FY (bulk sample) XANES shows that the [5]Ti is confined to the surface of the glass sample with the bulk of the glass containing [4]Ti.
Oriented inclusions of monazite occur in the dark core of apatite porphyroblasts in a muscovite schist from the Archaean Hemlo gold deposit, Ontario, Canada. The monazite inclusions are elongated along the b-axis and parallel to the c-axis of the apatite host; the complete orientation relationship of the monazite/apatite intergrowth is bMnz//cAp, cMnz//aAp. From analysis by SIMS and EMP, the dark core of the apatite porphyroblasts is depleted in LREE (LaN/YbN = 0.56). The monazite inclusions are correspondingly enriched in LREE, but markedly depleted in HREE, compared with monazite grains in the rock matrix and cross-cutting veins. The monazite inclusions precipitated by oriented reaction through rock-fluid interactions during a late hydrothermal alteration. Their unusual REE composition is probably related to both a preferential leaching of LREE from the dark core and a selective transfer of HREE out of the apatite porphyroblasts.
Allanite-(La) (containing up to 7.80 wt.% V2O3 and with La/ΣREE and La/Ce atomic ratios up to 0.54 and 1.45, respectively) and allanite-(Ce) (up to 8.46 wt.% V2O3) occur in close association with vanadian muscovite, barian tomichite and vanadian titanite in the main ore zone of the Hemlo gold deposit, Ontario, Canada. Allanite-(Ce) generally occurs as a minor constituent in cross-cutting veins or along foliation planes, whereas allanite-(La) invariably occurs in direct contact with titanite. The high V concentrations in the allanites from Hemlo are readily attributable to an adequate local source of this element, and are most likely controlled mainly by a simple substitution of V for Al in octahedral coordination. Vanadian allanite-(La) and vanadian allanite-(Ce), without any systematic differences in other constituents, are clearly distinct in REE composition, in respect to both the relative concentrations of La and Ce and abundances of other REE. The formation of both allanites (Ce- and La-rich) indicates very localised remobilisation and concentration of REE during a late hydrothermal alteration. The unusual REE composition of vanadian allanite-(La) directly reflects partitioning of REE with coexisting titanite, and the formation of this unusual phase may be attributable to replacement of earlier titanite with redistribution of REE in the solid state.
It remains unclear whether ST-elevation myocardial infarction (STEMI) patients transported by ambulance over long distances are at risk for clinical adverse events. We sought to determine the frequency of clinical adverse events in a rural population of STEMI patients and to evaluate the impact of transport time on the occurrence of these events in the presence of basic life support paramedics.
Methods
We performed a health records review of 880 consecutive STEMI patients transported to a percutaneous coronary intervention centre. Patients had continuous electrocardiogram and vital sign monitoring during transport. A classification of clinically important and minor adverse events was established based on a literature search and expert consensus. A multivariate ordinal logistic regression model was used to study the association between transport time (0-14, 15-29, ≥30 minutes) and the occurrence of overall clinical adverse events.
Results
Clinically important and minor events were experienced by 18.5% and 12.2% of STEMI patients, respectively. The most frequent clinically important events observed were severe hypotension (6.1%) and ventricular tachycardia/ventricular fibrillation (5.1%). Transport time was not associated with a higher risk of experiencing clinical adverse events (p=0.19), but advanced age was associated with adverse events (p=0.03). No deaths were recorded during prehospital transport.
Conclusions
In our study of rural STEMI patients, clinical adverse events were common (30.7%). However, transport time was not associated with the occurrence of adverse clinical events in these patients.
The Quebec Emergency Department Management Guide (QEDMG) is a unique document with 78 recommendations designed to improve the organization of emergency departments (EDs) in the province of Quebec. However, no study has examined how this guide is perceived or used by rural health care management.
Methods
We invited all directors of professional services (DPS), directors of nursing services (DNS), head nurses (HN), and emergency department directors (EDD) working in Quebec’s rural hospitals to complete an online survey (144 questions). Simple frequency analyses (percentage [%] and 95% confidence interval) were conducted to establish general familiarity and use of the QEDMG, as well as perceived usefulness and implementation of its recommendations.
Results
Seventy-three percent (19/26) of Quebec’s rural EDs participated in the study. A total of 82% (62/76) of the targeted stakeholders participated. Sixty-one percent of respondents reported being “moderately or a lot” familiar with the QEDMG, whereas 77% reported “almost never or sometimes” refer to this guide. Physician management (DPS, EDD) were more likely than nursing management (DNS and especially HN) to report “not at all” or “little” familiarity on use of the guide. Finally, 98% of the QEDMG recommendations were considered useful.
Conclusions
Although the QEDMG is considered a useful guide for rural EDs, it is not optimally known or used in rural EDs, especially by physician management. Stakeholders should consider these findings before implementing the revised versions of the QEDMG.