This article analyses the October 7th 2023 Hamas attack on Israel through the lens of the Genocide Convention, arguing that these actions constitute genocide under international law. Drawing on international case law, the analysis demonstrates how Hamas’ actions meet both the physical element and specific intent requirements for genocide, evidenced by its ideology, systematic policies and leadership statements. The article also examines how reverse accusations of genocide against Israel have functioned as a rhetorical shield to deflect recognition of Hamas’ own genocidal actions. It analyses the legal implications for state parties and the international community.

Sedentary occupation of the southern Levantine coast spans from the Pre-Pottery Neolithic C to the Early Bronze Age Ib phase (c. 7000–3100 BC). Sites dating to the Early Pottery Neolithic (c. 6400–5500 BC) are scarce, however, potentially reflecting the effects of the 8.2ka climatic event. Here, the authors present the investigations at the submerged site of Habonim North off the Carmel Coast. Typological and radiocarbon dating indicate an Early Pottery Neolithic occupation and evidence for continuity of subsistence and economic strategies with both earlier and later Neolithic cultures. The results indicate the resilience of coastal communities in the face of significant climatic uncertainty and contribute to understanding human responses to environmental change.

Knowledge graphs have become a common approach for knowledge representation. Yet, the application of graph methodology is elusive due to the sheer number and complexity of knowledge sources. In addition, semantic incompatibilities hinder efforts to harmonize and integrate across these diverse sources. As part of The Biomedical Translator Consortium, we have developed a knowledge graph–based question-answering system designed to augment human reasoning and accelerate translational scientific discovery: the Translator system. We have applied the Translator system to answer biomedical questions in the context of a broad array of diseases and syndromes, including Fanconi anemia, primary ciliary dyskinesia, multiple sclerosis, and others. A variety of collaborative approaches have been used to research and develop the Translator system. One recent approach involved the establishment of a monthly “Question-of-the-Month (QotM) Challenge” series. Herein, we describe the structure of the QotM Challenge; the six challenges that have been conducted to date on drug-induced liver injury, cannabidiol toxicity, coronavirus infection, diabetes, psoriatic arthritis, and ATP1A3-related phenotypes; the scientific insights that have been gleaned during the challenges; and the technical issues that were identified over the course of the challenges and that can now be addressed to foster further development of the prototype Translator system. We close with a discussion on Large Language Models such as ChatGPT and highlight differences between those models and the Translator system.

It is proved that for every positive integer n, the number of non-Tukey-equivalent directed sets of cardinality $\leq \aleph _n$ is at least $c_{n+2}$, the $(n+2)$-Catalan number. Moreover, the class $\mathcal D_{\aleph _n}$ of directed sets of cardinality $\leq \aleph _n$ contains an isomorphic copy of the poset of Dyck $(n+2)$-paths. Furthermore, we give a complete description whether two successive elements in the copy contain another directed set in between or not.

We prove that any element in a sufficiently large transitive finite simple permutation group is a product of two derangements.

Recent scholarship has challenged the still-powerful claim that long-distance pilgrimage and the journey to Jerusalem dramatically declined in number and significance in the sixteenth century. This article seeks to explore the different ways in which pilgrimage was embedded in the culture of the period. We interpret pilgrimage as a field of shared cross-confessional practices, representational conventions, and contestation. The paper presents a series of interlinked case studies, based on printed sources, correspondence, family archives, and material evidence. Together they demonstrate that early modern pilgrimage perpetuated medieval practices and yet was in constant dialogue with contemporary, post-Reformation religious and intellectual trends.

We show that the diameter of a uniformly drawn spanning tree of a simple connected graph on n vertices with minimal degree linear in n is typically of order $\sqrt{n}$. A byproduct of our proof, which is of independent interest, is that on such graphs the Cheeger constant and the spectral gap are comparable.

We report detailed chemical and isotopic data from a subglacial siliceous deposit on andesitic bedrock recently exposed by glacier retreat. Whereas a single, <1 μm, Si-rich layer covers the highly polished bedrock on the up-glacier (stoss) surfaces, distinct, lithified deposits commonly occur at the lee of small bedrock protuberances, on a scale <0.1 meter. The deposit is millimeters in thickness and consists of laminae tens to hundreds microns thick that differ from one another in color, rock-fragment abundance and chemical composition. Ca-rich laminae that are sufficiently enriched in uranium (~2–50 ppm) to permit U-series isotopic analysis suggest that the subglacial deposit formed 10–20 ka, much earlier than previously assumed. We conclude that (1) the siliceous deposit persisted for at least 10 000 years despite the intervening erosion and weathering, (2) distinct episodes of formation due to significant changes in hydrology and water chemistry are recorded in the deposit, and (3) a siliceous slurry may have existed at the ice-rock interface and influenced the local friction. This work reinforces earlier findings that subglacial chemical deposits can form and persist on geologic time scales and may have implications for the role of the cryosphere in the Earth's geochemical cycles and climate system.

As championed by the work of Ed Zigler, investing in nurturing environments for all children is a chief tenet of primary prevention that will have far-reaching benefits to the health and welfare of all members of society. Children who endure child maltreatment (CM) are among society's most vulnerable. Prospective longitudinal research aimed at a comprehensive understanding of the mechanisms linking CM to subsequent adverse health consequences is needed to improve outcomes and to strengthen causal inference. This paper outlines the methods of the Child Health Study (CHS), a large, state-wide longitudinal cohort of recently maltreated and nonmaltreated youth aged 8–13 who will be assessed every 2 years. The CHS is designed to include in-depth assessments of multiple environmental, behavioral, neural, physiological, and molecular mechanisms through which CM may impact a broad spectrum of youth development, including behavioral and physical health outcomes. In addition to describing the conceptual framework and methods underlying the CHS, we provide information on valuable “lessons learned” in the hopes of supporting future research efforts facing similar challenges. The ultimate goal of this research is demonstrating how policies regarding CM impact the well-being, resilience and recovery of survivors and that they are worthy of large public investment.

This article presents data on lexical development of 881 Israeli Hebrew-speaking monolingual toddlers ages 1;0 to 2;0. A Web-based version of the Hebrew MacArthur-Bates Communicative Development Inventories (H-MB-CDI) was used for data collection. Growth curves for expressive vocabulary, receptive vocabulary, actions and gestures were characterized. Developmental trajectories of toddlers with various demographic characteristics, such as education, income, religiosity level, birth order of the child, and child-care arrangements were compared. Results show that the lexical growth curves for Hebrew are comparable to those reported for other languages. Sex, birth order, and child-care arrangements were found to influence the size of lexicons. It is recommended that the trajectories presented here be used as norms for lexical growth among typical Hebrew-speaking toddlers in the second year of life.

Recent radiocarbon (14C) research demonstrates that the urban culture of Early-Bronze III in the southern Levant ends around 2500 BC, and not around 2300 BC as was widely assumed. This should extend the Intermediate Bronze Age by 200 years. Charred olive pits from Intermediate Bronze Age contexts in the site of Khirbat el-‘Alya Northeast in the Judean Shephelah region (Israel) were 14C dated, resulting in calibrated dates around 2500 BC. The date range of Khirbat el-‘Alya Northeast samples is an indication that in the Mediterranean parts of the southern Levant, the Intermediate Bronze Age material culture appeared around the time of the decline of the preceding culture of Early-Bronze III—around 2500 BC or somewhat earlier. Possible Intermediate Bronze settlement pattern and the site’s relation to the nearby Early-Bronze city of Tel Yarmuth are discussed based on previous Intermediate Bronze and Early-Bronze related research in the surrounding area.

Technical challenges associated with telomere length (TL) measurements have prompted concerns regarding their utility as a biomarker of aging. Several factors influence TL assessment via qPCR, the most common measurement method in epidemiological studies, including storage conditions and DNA extraction method. Here, we tested the impact of power supply during the qPCR assay. Momentary fluctuations in power can affect the functioning of high-performance electronics, including real-time thermocyclers. We investigated if mitigating these fluctuations by using an uninterruptible power supply (UPS) influenced TL assessment via qPCR. Samples run with a UPS had significantly lower standard deviation (p < 0.001) and coefficient of variation (p < 0.001) across technical replicates than those run without a UPS. UPS usage also improved exponential amplification efficiency at the replicate, sample, and plate levels. Together these improvements translated to increased performance across metrics of external validity including correlation with age, within-person correlation across tissues, and correlation between parents and offspring.