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Expert institutions are increasingly expected not only to provide the best professional expertise but also to ensure equal presence of women. Yet while descriptive gender representation in bureaucracies and courts is extensively researched, we largely lack studies of women’s presence on expert advisory bodies. Drawing on large-n data on the composition of Norwegian expert advisory commissions, the paper investigates and evaluates how the share of women on these commissions has developed over the last half-century. It finds that while overall gender parity was achieved in recent decades, women remain strongly under-represented among commission chairs, particularly academic chairs, and among academic members from the powerful economics discipline. Normatively speaking, the developments toward parity are promising, and we find no empirical indication that proportional representation and competence requirements are in tension. On the contrary, persistent gender gaps among economists on commissions and academic chairs may endanger adequate provision of expertise into policy-making.
Navigational safety is one of the important focuses of Maritime Education and Training (MET), and the quality of MET is the key to cultivating competent officers at sea. This study aims to understand better the effects of a rapid training method on ship handling and navigation in restricted waters, as well as decision-making skills under stressful situations. Tests were carried out in a simulator-based maritime training environment to explore the decision-making skills of maritime students in stressful situations under different training levels and methods. This study compares routine maritime training and task-aimed rapid training in improving manoeuvring and navigational and decision-making skills, and examines the training outcomes. The data used in this study is based on comparing the task performance and stress levels of the two groups of students using simulator-based training results from a designed scenario. The results analyse the training outcomes of decision-making skills and maritime operation performance by applying a specific decision-making model. In addition, the impact of students' stress levels was examined, both subjectively and objectively. The paper concludes with a set of recommendations for the design of future MET. The research helps enhance decision-making skills in maritime training programmes and understanding how learning in simulator-based maritime training environments can be improved.
Previous research has shown that short-term changes in blood glucose influence our preferences and may affect decisions about risk as well. However, consensus is lacking about whether and how blood glucose influences decision making under risk, and we conduct two experiments and a meta-analysis to examine this question in detail. In Study 1, using a pecuniary valuation method, we find no effect of blood glucose on willingness to pay for risky products that may act as allergens. In Study 2, using risky gambles, we find that low levels of blood glucose increase risk taking for food and to a lesser degree for non-food rewards. Combining our own and previous findings in a meta-analysis, we show that low levels of blood glucose on average increase risk taking about food. Low blood glucose does not increase risk taking about non-food rewards although this is subject to heterogeneity. Overall, our studies suggest that low blood glucose increases our willingness to gamble on how much food we can get, but not our willingness to eat food that can harm us. Our findings are best explained by the energy budget rule.
Adherence to injectable disease-modifying treatments in patients with multiple sclerosis (MS) impacts outcomes and can be influenced by perceptions of treatment efficacy, side effects, injection frequency, and the duration of injection. This study aimed to quantify preferences for selected attributes of injectable treatments among individuals with MS in the United Kingdom and France.
Methods:
Respondents with a self-reported diagnosis of MS completed an online discrete-choice-experiment survey, consisting of a series of treatment-choice questions. Each choice question presented two hypothetical treatments, each with six attributes (years until disability progression, relapses in the next 4 years, injection time, injection frequency, flu-like symptoms (FLS), and injection-site reactions), each with various levels. Mixed-logit regression analysis was used to estimate preference weights for attribute levels and to calculate the relative importance of changes in treatment attributes (vertical distance between preference weights). Minimum acceptable efficacy estimates indicate improvement in efficacy that respondents would require in exchange for worsening injection frequency and FLS.
Results:
In both countries, 100 respondents completed the survey. In the United Kingdom and France, respectively, improving the time until disability progression from 2 to 4 years, reducing injection frequency from “daily” to “every 2 weeks”, and reducing FLS from 3 days after every injection to none had a relative importance of 2.9 and 2.6, 3.0 and 3.5, and 2.5 and 3.1. Given the ranges included in the study, changes in these attributes were more important than most changes in other attributes assessed.
Conclusions:
Reductions in the injection frequency of MS treatments and FLS can be as important to patients as improvements in treatment efficacy.
Assuming a channelized drainage system in steady state, we investigate the influence of enhanced surface melting on the water pressure in subglacial channels, compared to that of changes in conduit geometry, ice rheology and catchment variations. The analysis is carried out for a specific part of the western Greenland ice-sheet margin between 66° N and 66°30′N using new high-resolution digital elevation models of the subglacial topography and the ice-sheet surface, based on an airborne ice-penetrating radar survey in 2003 and satellite repeat-track interferometric synthetic aperture radar analysis of European Remote-sensing Satellite 1 and 2 (ERS-1/-2) imagery, respectively. The water pressure is calculated up-glacier along a likely subglacial channel at distances of 1, 5 and 9 km from the outlet at the ice margin, using a modified version of Röthlisberger’s equation. Our results show that for the margin of the western Greenland ice sheet, the water pressure in subglacial channels is not sensitive to realistic variations in catchment size and mean surface water input compared to small changes in conduit geometry and ice rheology.
Antipsychotics are associated with a polymorphic ventricular tachycardia, torsades de pointes, which, in the worst case, can lead to sudden cardiac death. The QT interval corrected for heart rate (QTc) is used as a clinical proxy for torsades de pointes. The QTc interval can be prolonged by antipsychotic monotherapy, but it is unknown if the QTc interval is prolonged further with antipsychotic polypharmaceutical treatment. Therefore, this study investigated the associations between QTc interval and antipsychotic monotherapy and antipsychotic polypharmaceutical treatment in schizophrenia, and measured the frequency of QTc prolongation among patients.
Methods
We carried out an observational cohort study of unselected patients with schizophrenia visiting outpatient facilities in the region of Central Jutland, Denmark. Patients were enrolled from January of 2013 to June of 2015, with follow-up until June of 2015. Data were collected from clinical interviews and clinical case records.
Results
Electrocardiograms were available for 65 patients, and 6% had QTc prolongation. We observed no difference in average QTc interval for the whole sample of patients receiving no antipsychotics, antipsychotic monotherapy, or antipsychotic polypharmaceutical treatment (p=0.29). However, women presented with a longer QTc interval when receiving polypharmacy than when receiving monotherapy (p=0.01). A limitation of this study was its small sample size.
Conclusions
We recommend an increased focus on monitoring the QTc interval in women with schizophrenia receiving antipsychotics as polypharmacy.
Strong absorption lines in quasar spectra primarily probe low-mass galaxies and detecting these in emission has previously been difficult. Dedicated surveys for the host galaxies of damped Lyman-α (DLA) systems have often resulted in non-detections and upper limits. Targeting the most metal-rich absorbers has proven to be a viable method, because these galaxies are brighter. By combining DLA metallicities and deriving host galaxy stellar masses, we find that metal-rich DLAs (with >10% solar metallicity) and their host galaxies follow the same redshift-dependent scaling relation between stellar mass and metallicity as luminosity-selected galaxies. We derive a prediction for an absorber galaxy mass that depends on the DLA metallicity.
Metamaterials are man-made designer matter that obtains its unusual effective properties by structure rather than chemistry. Building upon the success of electromagnetic and acoustic metamaterials, researchers working on mechanical metamaterials strive at obtaining extraordinary or extreme elasticity tensors and mass-density tensors to thereby mold static stress fields or the flow of longitudinal/transverse elastic vibrations in unprecedented ways. In this prospective paper, we focus on recent advances and remaining challenges in this emerging field. Examples are ultralight-weight, negative mass density, negative modulus, pentamode, anisotropic mass density, Origami, nonlinear, bistable, and reprogrammable mechanical metamaterials.
New Zealand moved further in neo-liberal tax reform than most other advanced economies over the last three decades. The article investigates this extreme case to address the question of what explains major neo-liberal economic reform. Comparing tax policy-making in two periods, the 1980s and 2008–10, we argue that neo-liberal tax reform in New Zealand is best understood as the product of “autonomous bureaucratic action”. That is, bureaucratic organisations within the state independently formulated the goals and ideas for reform, took an activist role in policy-making and strongly influenced the policy preferences of ministers. Moreover, responding to a criticism often raised against state-centred theories, we offer an explicit explanation of bureaucratic preferences. We argue that bureaucratic goals and ideas were a product of how particular structural features of the bureaucracy – organisation and training – made ministries more or less receptive to new ideas within the economics discipline.
We present spatially resolved emission line studies of three nearby GRB and SN hosts with longslit and/or IFU observations. We compare the environment of the GRBs/SNe with those of other star-forming regions in the host galaxy and try to get informations on the progenitor from stellar population models and metallicities.
Those with first-episode psychosis are at high-risk of suicide
Aims
To identify predictive factors for suicidal thoughts, plans and attempts, and to investigate the rate of suicides and other deaths during the 5 years after first diagnosis and initiation of treatment
Method
A longitudinal, prospective, 5-year follow-up study of 547 individuals with first-episode schizophrenia spectrum psychosis. Individuals presenting for their first treatment in mental health services in two circumscribed urban areas in Denmark were included in a randomised controlled trial of integrated v. standard treatment. All participants were followed in the Danish Cause of Death Register for 5 years. Suicidal behaviour and clinical and social status were assessed using validated interviews and rating scales at entry, and at 1- and 2-year follow-ups
Results
Sixteen participants died during the follow-up. We found a strong association between suicidal thoughts, plans and previous attempts, depressive and psychotic symptoms and young age, and with suicidal plans and attempts at 1- and 2-year follow-up
Conclusions
In this first-episode cohort depressive and psychotic symptoms, especially hallucinations, predicted suicidal plans and attempts, and persistent suicidal behaviour and ideation were associated with high risk of attempted suicide
The families of patients with first-episode psychosis often play a major role in care and often experience lack of support.
Aims
To determine the effect of integrated treatment v. standard treatment on subjective burden of illness, expressed emotion (EE), knowledge of illness and satisfaction with treatment in key relatives of patients with a first episode of schizophrenia-spectrum disorder.
Method
Patients with ICD-10 schizophrenia-spectrum disorders (first episode) were randomly assigned to integrated treatment or to standard treatment. Integrated treatment consisted of assertive community treatment, psychoeducational multi-family groups and social skills training. Key relatives were assessed with the Social Behaviour Assessment Schedule (SBAS, burden of illness), the 5-min speech sample (EE), and a multiple choice questionnaire at entry and after 1 year.
Results
Relatives in integrated treatment felt less burdened and were significantly more satisfied with treatment than relatives in standard treatment. There were no significant effects of intervention groups on knowledge of illness and EE.
Conclusions
The integrated treatment reduced family burden of illness and improved satisfaction with treatment.
Because early illness course and outcome may affect the long-term outcome of schizophrenia-spectrum disorders, it is especially important to address poor outcome in this early critical period.
Aims
To evaluate whether integrated treatment compared with standard treatment reduced the proportion of patients with poor clinical and social outcome after 1 year.
Method
A total of 547 patients with first-episode psychosis were included in the study, 275 randomly assigned to integrated treatment and 272 to standard treatment. Measures assessed psychotic symptoms and social functioning.
Results
There was a significant beneficial effect of integrated treatment v. standard treatment on ‘any poor outcome’. Integrated treatment had a significantly better effect on ‘any poor outcome’ in patients with schizophrenia compared with patients in standard treatment.
Conclusions
The integrated treatment significantly reduced the proportion of patients with poor clinical and social outcome compared with standard treatment.
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