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We analyze nearly 70,000 New York City criminal court arraignments to examine how judges’ professional backgrounds influence pretrial detention. We classify judges as having experience in law enforcement, legal services, both, or neither. Judges with law enforcement backgrounds are, on average, 3.9 percentage points more likely than others to order detention and impose cash bail. When bail is imposed, they set amounts about 32% higher. No significant differences emerge for legal services backgrounds. Because law enforcement experience is common among judges, our findings have broad implications for pretrial detention nationwide.
Structural brain alterations in bipolar disorder (BD) have been widely reported, yet the hierarchical organization of cortical morphometric networks and their molecular and cognitive underpinnings remain unclear.
Methods
We applied the morphometric inverse divergence (MIND) network approach to structural MRI data from 49 BD patients and 119 healthy controls. Principal MIND gradients were derived using diffusion map embedding, followed by multiscale analyses linking gradient alterations to neurotransmitter systems, cognitive-behavioral domains, and transcriptomic profiles from the Allen Human Brain Atlas. Validation was performed in three independent, cross-scanner, cross-race, and cross-age validation datasets.
Results
Bipolar disorder patients showed significant principal gradient alterations in the left rostral middle frontal and lateral occipital cortices, with network-level decreases in the ventral attention and motor networks and increases in frontoparietal and visual networks. Gradient alterations spatially correlated with acetylcholine (VAChT) and GABA (GABAA/BZ) systems, and were associated with cognitive processes involving executive control and visual attention. Transcriptomic analyses identified gene sets enriched for BD-related GWAS loci, expressed predominantly in excitatory and inhibitory neurons, astrocytes, and oligodendrocytes, with preferential enrichment in cortical layers III-IV and developmental windows spanning early fetal to young adulthood.
Conclusions
These findings reveal disrupted hierarchical cortical organization in BD and link macroscale morphometric alterations to specific neurotransmitter systems and transcriptional architectures. The MIND gradient emerges as a potential biomarker bridging structural disruptions with molecular and cognitive mechanisms in BD.
Treaties of the European Union – Comprehensive framework for macro-economic governance, devoid of democratic influence – Divergence from this seemingly stringent framework during the Euro Crisis and the Covid-19 pandemic – Pattern of deviation from the macro-constitution – Euro Crisis and Next Generation EU illustrate that deviations can safeguard the macro-constitution, preserving rather than transforming the Union’s macro-constitution.
This study evaluates the extent of separation of religion and state (SRAS) in 28 countries which were European Union members in 2014 using data from the Religion and State (RAS) dataset. It applies three different standards of SRAS: absolute separationism, neutralism, and laicite. The results show that none of these countries meet a “zero-tolerance” application of any of these standards, and only five meet even very loose interpretations of any of these standards. In addition, no EU state provides full religious freedom to their religious minorities. Finally, EU states have less SRAS when compared to non-EU democracies. This calls into question either the assumption that SRAS and religious freedom are essential elements of liberal democracy or the assumption that the European Union’s member states are, in fact, liberal democracies. It also calls into question the extent of the West’s secularity.
Here we report microfossil helminth analysis of soils/sediments from the Cloudman site, Lake Huron, Michigan, encompassing the Early Late Woodland (AD 500/600–1000) to the early Historic period. Results reveal eggs of the dog nematode Toxocara canis (a first for North America), the human nematode Ascaris lumbricoides, and a species of taeniid cestode, intestinal parasites that could have affected the health of people and their domesticated dogs. The eggs suggest that the presence of dogs at the site remained relatively stable over the c. 1000-year span of this period. The results offer a new line of evidence for possible dog presence and domestication in North America.
A thin, evaporating sessile droplet with a pinned contact line containing inert particles is considered. In the limit in which the liquid flow decouples from the particle transport, we discuss the interplay between particle advection, diffusion and adsorption onto the solid substrate on which the droplet sits. We perform an asymptotic analysis in the physically relevant regime in which the Péclet number is large, i.e. ${\textit{Pe}}\gg 1$, so that advection dominates diffusion in the droplet except in a boundary layer near the contact line, and in which the ratio of the particle velocities due to substrate adsorption and diffusion is at most of order unity as ${\textit{Pe}}\rightarrow \infty$. We use the asymptotic model alongside numerical simulations to demonstrate that substrate adsorption leads to a different leading-order distribution of particle mass compared with cases with negligible substrate adsorption, with a significant reduction of the mass in the suspension – the nascent coffee ring reported in Moore et al. (J. Fluid Mech., vol. 920, 2021, A54). The redistribution leads to an extension of the validity of the dilute suspension assumption, albeit at the cost of breakdown due to the growth of the deposited layer, which are important considerations for future models that seek to accurately model the porous deposit regions.
In this paper, we study the cohomology of the unitary unramified PEL Rapoport-Zink space of signature $(1,n-1)$ at hyperspecial level. Our method revolves around the spectral sequence associated to the open cover by the analytical tubes of the closed Bruhat-Tits strata in the special fiber, which were constructed by Vollaard and Wedhorn. The cohomology of these strata, which are isomorphic to generalized Deligne-Lusztig varieties, has been computed in an earlier work. This spectral sequence allows us to prove the semisimplicity of the Frobenius action and the non-admissibility of the cohomology in general. Via p-adic uniformization, we relate the cohomology of the Rapoport-Zink space to the cohomology of the supersingular locus of a Shimura variety with no level at p. In the case $n=3$ or $4$, we give a complete description of the cohomology of the supersingular locus in terms of automorphic representations.
Ionic surfactants are commonly employed to modify the rheological properties of fluids, particularly in terms of surface viscoelasticity. Concurrently, external electric fields can significantly impact the dynamics of liquid threads. A key question is how ionic surfactants affect the dynamic behaviour of threads in the presence of an electric field? To investigate this, a one-dimensional model of a liquid thread coated with surfactants within a radial electric field is established, employing the long-wave approximation. We systematically investigate the effects of dimensionless parameters associated with the surfactants, including surfactant concentration, dilatational Boussinesq number ${\textit{Bo}}_{\kappa \infty }$ and shear Boussinesq number ${\textit{Bo}}_{\mu \infty }$. The results indicate that increasing the surfactant concentration and the two Boussinesq numbers reduces both the maximum growth rate and the dominant wavenumber. In addition, both the electric field and surfactants mitigate the breakup of the liquid thread and the formation of satellite droplets. At low applied electric potentials, the surface viscosity induced by surfactants predominantly governs this suppression. Surface viscosity suppresses the formation of satellite droplets by maintaining the neck point at the centre of the liquid thread within a single disturbance wavelength. When the applied potential is high, the electric stress has two main effects: the external electric field exerts a normal pressure on the liquid thread surface, suppressing satellite droplet formation, while the internal electric field inhibits liquid drainage. Surface viscosity further stabilizes the system by suppressing flow dynamics during this process.
Artificial intelligence is reshaping the contemporary world. Trickling deeper into archaeology and history, these technological changes will influence how the past is written about and visualized. Through the evaluation of text and images generated using AI, this article considers the systemic biases present in reconstructed archaeological scenes. We draw on advances in computer science, running large-scale, computational analyses to evaluate patterns in content. We present a case study examining Neanderthal behavior, juxtaposing published archaeological knowledge with images and text made using AI. Our study reveals a low correspondence between scientific literature and artificially intelligent material, which reflects dated knowledge and cultural anachronisms. Used to identify patterns in (mis)representations of the past, the methodology can be applied to understand the distance between scholarly knowledge and any domain of content generated using AI, across any archaeological time depth and beyond the discipline.
Digital financial inclusion (DFI) has been widely recognized for its potential role in reducing poverty by fostering entrepreneurship. However, whether DFI benefits all social classes equally remains an open question. Integrating technology adoption and income stratification research, this study investigates the impact of DFI on income stratification – specifically lower-, middle-, and upper-income classes – across key entrepreneurial stages, including venture creation, investment, and performance. Using data from 36,557 household-wave observations in the China Household Financial Survey (CHFS), we find that (1) lower-class households are less likely to establish entrepreneurial ventures compared to upper-class households but are more likely to do so than middle-class households, and (2) they make lower investments in entrepreneurial ventures compared to their upper-class counterparts, and experience lower entrepreneurial performance than middle- and upper-class households. The results also show that, whereas DFI positively influences entrepreneurial venture creation, investment, and performance for lower-class households, these effects are less pronounced compared to those observed in middle- and upper-class households. The study advances an integrated view of DFI by examining its differential impacts across income classes and entrepreneurial stages and contributes to the ongoing debate about its effectiveness as a universal poverty reduction solution.
Consultation-liaison psychiatry (CLP) refers to the subspecialty of psychiatry and the specialist clinical services that deliver care at the intersection of mental and physical healthcare. CLP services provide specialist medical and multidisciplinary expertise for managing conditions in these areas of mental and physical healthcare overlap, and comorbidity. The Model of Care for CLP was identified as a key priority in Sharing the Vision, the 2020 national mental health policy in Ireland. Following four years of work by a writing group initiated by the Faculty of Liaison Psychiatry at the College of Psychiatrists of Ireland, the Model of Care for CLP in Ireland was launched in May 2025 (Cpsychi H (2025). Consultation-Liaison Psychiatry: A Model of Care for Ireland. Dublin: HSE.).). Consultation-Liaison Psychiatry: A Model of Care for Ireland. Dublin: HSE.). This reflects the collaborative efforts between the Liaison Faculty and the Irish Health Service Executive (HSE). This Model of Care, developed in collaboration with clinicians and patients, the College of Psychiatrists of Ireland, and the HSE, provides a potential template for future collaborations in the development and implementation of National Mental Health policy.
Sustainable management of watersheds to secure freshwater resources and maintain ecological stability relies on adopting land-use strategies supporting diverse ecosystem services through natural processes. This necessitates systematic evaluation of prospective land-use practices and their associated costs and benefits. We conducted a comprehensive economic evaluation of pro-watershed land-use options, focusing on a well-recognized agroforestry system with alternative organic cultivation in the Navnera watershed in Rajasthan, India. We adopted the ‘total economic valuation’ framework, using the revealed preference approach for monetary evaluation and modelling indirect benefits primarily through Integrated Valuation of Ecosystem Services and Tradeoffs (InVEST). Our findings indicate that the total economic value of ecosystem services in this watershed has the potential to increase by 4.6% with the adoption of agroforestry and only by 1.3% under organic farming compared to current land-use practices. While agroforestry might reduce farmland revenue and water yield, it compensates for these with other important environmental benefits such as water purification, sediment reduction, nutrient retention and carbon sequestration. This local-scale appraisal of ecosystem services helps policymakers understand the cost–benefit dynamics of watershed land-use changes, which is vital for developing effective management strategies through the involvement of local communities.
As a step towards realising a skin-friction drag reduction technique that scales favourably with Reynolds number, the impact of a synthetic jet on a turbulent boundary layer was explored through a study combining wind-tunnel measurements and large eddy simulations. The jet was ejected in the wall-normal direction through a rectangular slot whose spanwise dimension matched that of dominant large-scale structures in the logarithmic region to target structures of that size and smaller simultaneously. Local skin-friction reduction was observed at both $x/\delta =2$ and $x/\delta =5$ downstream of the orifice centreline, where $\delta$ is the boundary-layer thickness. At $x/\delta =2$, the skin-friction reduction was observed to be due to the synthetic-jet velocity deficit intersecting the wall. At $x/\delta =5$, evidence from the simulations and wind-tunnel measurements suggests that a weakening of wall-coherent velocity scales is primarily responsible for the skin-friction reduction. Local skin-friction reduction which scales favourably with Reynolds number may be achievable with the synthetic jet employed in this study. However, there are many technical hurdles to overcome to achieve net skin-friction drag reduction over the entire region of influence. For instance, regions of skin-friction increase were observed close to the orifice ($x/\delta \lt 2$) and downstream of the orifice edge due to the induced motion of synthetic-jet vortical structures. Additionally, a recirculation region was seen to form during expulsion, which has implications for pressure drag on non-planar surfaces.
Northern Calabria forms part of the Calabrian Arc, a geologically complex region in southern Italy shaped by the convergence between the Eurasian and African plates. This convergence drove the closure of the Tethys Ocean and produced the subsequent phases of collisional and extensional tectonics. Thrusting during the Alpine orogeny produced extensive nappe stacking, followed by structural reorganization and exhumation during the Oligocene-Miocene. Tectonostratigraphically, the Apennine carbonate platform forms the lowest structural unit, overlain successively by the Liguride Oceanic Complex and the Calabride Complex, which includes the Sila nappe stack. Along Calabria’s eastern Ionian margin, forearc basins developed in response to the retreating subduction zone. To better constrain sediment routing pathways and regional uplift in northern Calabria from early to late Miocene, a multi-proxy provenance study was applied to four forearc basins: Rossano, Cirò, Crotone and Catanzaro. Quantitative heavy-mineral analysis, single-grain garnet and apatite chemistry, and apatite U–Pb chronology reveal spatial and temporal variations in sediment sources. Siliciclastic samples, spanning Aquitanian to Messinian in age, record changing contributions from a combination of low- to high-grade metamorphic and plutonic sources, including mafic Liguride units. Up-section shifts in sediment sourcing patterns indicate that Calabrian Arc exhumation and uplift, characterized by a rapid increase in the middle Miocene followed by a slow reduction in relief, played a pivotal role in controlling the timing and direction of sediment transport. This study demonstrates the benefits of multi-method provenance approaches to achieve valuable insights into relief build-up and demise, associated divide migration and sedimentary responses within a young and complex, zircon-poor orogenic arc system.