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Accountability for developing, deploying, and using any emerging weapons system is affirmed as a guiding principle by the Group of Governmental Experts on Emerging Technologies in the Area of Lethal Autonomous Weapons Systems. Yet advances in emerging technologies present accountability challenges throughout the life cycle of a weapons system. Mindful of a lack of progress at the Convention on Certain Conventional Weapons since 2019, this essay argues for a mechanism capable of imputing accountability when individual agent accountability is exceeded, forensic accountability unreliable, and aspects of political accountability fail.
The US Food and Drug Administration’s controversial decision to grant accelerated approval to aducanumab (Aduhelm), a therapy for Alzheimer’s disease, has motivated multiple policy reforms. Drawing a case series of other drugs granted accelerated approval and interviews of senior FDA officials, I argue that reform should be informed but not defined by aducanumab. Rather, structural reforms are needed to reshape FDA’s core priorities and restore the regulatory system’s commitment to scientific rigor.
We study conjugacy classes of germs of nonflat diffeomorphisms of the real line fixing the origin. Based on the work of Takens and Yoccoz, we establish results that are sharp in terms of differentiability classes and order of tangency to the identity. The core of all of this lies in the invariance of residues under low-regular conjugacies. This may be seen as an extension of the fact (also proved in this article) that the value of the Schwarzian derivative at the origin for germs of $C^3$ parabolic diffeomorphisms is invariant under $C^2$ parabolic conjugacy, though it may vary arbitrarily under parabolic $C^1$ conjugacy.