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Among 143 cases of National Healthcare Safety Network (NHSN) catheter-associated urinary tract infections (CAUTI), 40% were considered catheter-associated asymptomatic bacteriuria (CA-ASB), and 18% clinical CAUTI. An alternative source of fever was present in 70% of CA-ASB. NHSN CAUTI may not be an effective metric for tracking hospital-level infection prevention efforts.
Text classification methods have been widely investigated as a way to detect content of low credibility: fake news, social media bots, propaganda, etc. Quite accurate models (likely based on deep neural networks) help in moderating public electronic platforms and often cause content creators to face rejection of their submissions or removal of already published texts. Having the incentive to evade further detection, content creators try to come up with a slightly modified version of the text (known as an attack with an adversarial example) that exploit the weaknesses of classifiers and result in a different output. Here we systematically test the robustness of common text classifiers against available attacking techniques and discover that, indeed, meaning-preserving changes in input text can mislead the models. The approaches we test focus on finding vulnerable spans in text and replacing individual characters or words, taking into account the similarity between the original and replacement content. We also introduce BODEGA: a benchmark for testing both victim models and attack methods on four misinformation detection tasks in an evaluation framework designed to simulate real use cases of content moderation. The attacked tasks include (1) fact checking and detection of (2) hyperpartisan news, (3) propaganda, and (4) rumours. Our experimental results show that modern large language models are often more vulnerable to attacks than previous, smaller solutions, e.g. attacks on GEMMA being up to 27% more successful than those on BERT. Finally, we manually analyse a subset adversarial examples and check what kinds of modifications are used in successful attacks.
Trends in elemental enrichment with stellar age can give us a powerful avenue to identify thus far unexplained origin sites of the elements. We investigate stellar abundance trends using the GALAH DR3 high-resolution spectroscopic dataset of 6 234 solar-type stars. Our study explores the elemental abundance [X/Fe] of sodium (Na) with stellar age. We find a pronounced enrichment in [Na/Fe] at super solar metallicity (i.e. [Fe/H] $ \gt \,0$) in the old sequence of Milky Way disc stars, a trend demanding a deeper understanding of the underlying source(s) responsible for the nucleosynthesis. This progressive [Na/Fe] enrichment at the young end of the old sequence has essential implications for Galactic archaeology. In this work, we propose a novel selection technique for separating the Milky Way’s thick and thin disc stellar populations (i.e. old and young sequences) based on the observed [Na/Fe] rise of $\sim$0.1 dex for stars around 5–8 Gyr old. We also compare our selection method to the conventional [Mg/Fe] vs. [Fe/H] selection approach, and we find that our new Na-based selection method better disentangles the overlap between young- and old-sequence disc stars at these intermediate ages. This is especially true at super solar [Fe/H], where the [Mg/Fe] vs. [Fe/H] or [$\alpha$/Fe] vs. [Fe/H] separation approaches exhibit significant overlap. This new selection method should help us better understand the history of the formation of the Milky Way disc.
Self-supervised representation learning (SSRL) in computer vision relies heavily on simple image transformations such as random rotation, crops, or illumination to learn meaningful and invariant features. Despite acknowledged importance, there is a lack of comprehensive exploration of the impact of transformation choice in the literature. Our study delves into this relationship, specifically focusing on microscopy imaging with subtle cell phenotype differences. We reveal that transformation design acts as a form of either unwanted or beneficial supervision, impacting feature clustering and representation relevance. Importantly, these effects vary based on class labels in a supervised dataset. In microscopy images, transformation design significantly influences the representation, introducing imperceptible yet strong biases. We demonstrate that strategic transformation selection, based on desired feature invariance, drastically improves classification performance and representation quality, even with limited training samples.
Fast and efficient identification is critical for reducing the likelihood of weed establishment and for appropriately managing established weeds. Traditional identification tools require either knowledge of technical morphological terminology or time-consuming image matching by the user. In recent years, deep learning computer vision models have become mature enough to enable automatic identification. The major remaining bottlenecks are the availability of a sufficient number of high-quality, reliably identified training images and the user-friendly, mobile operationalization of the technology. Here, we present the first weed identification and reporting app and website for all of Australia. It includes an image classification model covering more than 400 species of weeds and some Australian native relatives, with a focus on emerging biosecurity threats and spreading weeds that can still be eradicated or contained. It links the user to additional information provided by state and territory governments, flags species that are locally reportable or notifiable, and allows the creation of observation records in a central database. State and local weed officers can create notification profiles to be alerted of relevant weed observations in their area. We discuss the background of the WeedScan project, the approach taken in design and software development, the photo library used for training the WeedScan image classifier, the model itself and its accuracy, and technical challenges and how these were overcome.
The primary objectives of this umbrella review were to (a) quantify the relative importance, of “severity” and “rarity” criteria in health resource allocation; and (b) analyze the contextual factors influencing the relative importance. The secondary objective was to examine how “severity” and “rarity” criteria are defined.
Methods
Searches were carried out in PubMed and Embase to identify eligible systematic reviews. Quality appraisal of systematic reviews was undertaken. From identified systematic reviews, primary studies were extracted and further screened for eligibility. The inclusion of severity and rarity criteria and their respective weights in primary studies were examined. Descriptive and regression analyses were performed.
Results
Twenty-nine systematic reviews were screened, of which nine met the inclusion criteria. Primary studies included in these systematic reviews were retrieved and screened, resulting in forty articles included in the final analysis. Disease severity was more frequently considered (n = 29/40) than disease rarity (n = 23/40) as an evaluation criterion. Out of all cases where both were included as evaluation criteria, disease severity was assigned higher weights 84 percent of the time (n = 21/25).
Conclusions
Our review found consistent evidence that disease severity is more relevant and preferred to rarity as a priority-setting criterion albeit constraints in statistical analysis imposed by limited sample size and data availability. Where funding for rare diseases is concerned, we advocate that decision-makers be explicit in clarifying the significance of disease severity and/or rarity as a value driver behind decisions. Our findings also reinforce the relevance of disease severity as a criterion in priority setting.
The All-Affected Principle is of limited help in thinking about immigration. Immigration raises important normative questions about who should have access to citizenship, what is required for the full social and economic inclusion of immigrants, what legal rights immigrants admitted by a state should have, how migrants who enter and settle without permission should be treated, what criteria should be used in selecting and excluding immigrants, what states ought to do in dealing with refugees, and whether controlling immigration is really morally justifiable at all. The All-Affected Principle is directly relevant only to the first question of who should have access to citizenship, and even in that case, it needs to be supplemented. The other questions are not primarily about who should participate in democratic decision-making but about what justice requires and about the moral constraints on democratic discretion. So, using the All-Affected Principle to think about those questions would not help, and starting from that principle in thinking about immigration might lead us to miss the key normative issues.
As labor in the capitalist system practically tripled to some three billion workers, solidary organizations of labor simultaneously dwindled in relative size and power. This is true globally but also for the historical core countries. While this is a paradox, it is not a contradiction. Capital is a (spatialized) social relationship. The globalization of capital since the 1970s has shifted the power relations with localized labor fundamentally in favor of capital, as Charles Tilly noted in this journal almost thirty years ago. Over time, power balances within capitalist states, and between capitalist states and transnationalizing capital, have reflected that basic class-relational shift. This article explains why the globalizing cycle of weakened labor may now be reversing.
We report the non-breeding range of an adult Rapa Shearwater Puffinus myrtae, as estimated from data collected by one light logger deployed from 31 August 2019 to 22 July 2020. The Rapa Shearwater is classified as “Critically Endangered”, with a strong decline in breeding numbers reported recently. As the species is threatened by various introduced mammals on the breeding colonies, the main objective of this tracking essay was to identify the oceanic regions where the birds forage during the non-breeding season. The non-breeding range of this bird was located south-east of Rapa Island, where fishery activities are limited. The conservation efforts for the Critically Endangered Rapa Shearwater should first focus on securing mammal-free sites for breeding colonies.
This paper investigates the take-off performance of a single engine battery-electric aeroplane, using the example of the 300kg Sherwood eKub. It shows analysis of take-off performance of such an aeroplane must include as a minimum two new parameters not normally considered: time at full throttle and state of charge. It was shown in both ground and flight test that the state of available power reduces both as the throttle is fully open, and as battery charge is consumed, although recovers partially when power is reduced for a period. It is possible to schedule take-off performance as a function of the usual parameters plus state of charge. Because of the reducing climb performance with use of state of charge, and the requirement in airworthiness standards for minimum climb performance being available, it becomes necessary to introduce the concept of minimum-indicated state of charge for take-off, SoCiMTO; means to calculate that are shown for compliance with both microlight aeroplane standards and larger aeroplane standards, and the calculations are demonstrated for the eKub. Conclusions are also drawn about the use of commercial products SkyDemon and Google Earth for recording and analysing aeroplane performance data.
The One Health High-Level Expert Panel’s definition of One Health includes optimizing the health of people, animals (wild and domestic) and ecosystems. For many One Health practitioners, wildlife that can spread zoonoses are the focus, particularly if they can come in contact with people. However, ecosystem health is often best-indicated by less-encountered species, for instance, amphibians and reptiles. This review highlights how these taxa can benefit human health and well-being, including cultural significance, as well as their impact on plant, animal and environmental health. We highlight current challenges to the health of these species and the need to include them in the One Health Joint Action Plan. We conclude with a call to action for inclusion of amphibians and reptiles in a One Health approach.
Post-excavation analysis of individual Ghz-1-002, an adult probable male interred in a medieval cemetery at Ghazali, Sudan, identified tattoos on the right foot. Visualisation under different spectrums of light allowed a reconstruction of the marks, which are only the second instance of tattooing identified from medieval Nubia.
Discriminatory morpho-metric features are obvious on legume seeds. This study utilized seven quantitative and 11 qualitative seed traits to characterize 139 African yam bean (AYB) breeding lines which were developed through single seed descent procedure. The seven quantitative data were subjected to analysis of variance, their means were combined with qualitative scores for genetic distance, principal component (PC) and clustering analyses. Significant (P ≤ 0.001) variation existed among the breeding lines for the seven traits. Mean ranges of seed length (SL), width (SW), thickness (ST) and a single seed weight (SSW) among the 139 breeding lines were respectively: 6.77–10.22 mm, 5.70–7.86 mm, 4.96–7.45 mm and 0.15–0.42 g. Positive and significant (P ≤ 0.05) genotypic correlation existed among SSW, SL, SW and ST. Seed colours, pattern, shapes, sizes, surface texture, brilliance varied among the breeding lines. Ranges of phenotypic and genotypic coefficient of variation and broadsense heritability were: 5.49–23.84%, 2.95–19.88% and 28.91–69.54% respectively. Fourteen (quantitative and qualitative) traits contributed higher (≥ 0.30) eigenvector loadings to the first three PC axes which explained 57.9% of the total variation among the breeding lines. Similarity among the lines was 0.75. Four clusters ensued in the dendrograph and each group had genetic similarities of: 0.85 (I), 0.82 (II), 0.78 (III) and 0.80 (IV). This research unveiled significant variation among AYB breeding lines with promising reliability for breeding opportunities of the qualitative and quantitative seed traits, which could contribute to higher grain yield and acceptability.
Computerized clinical decision support (CDS) assists healthcare professionals in making decisions to improve patient care. In the realms of antimicrobial stewardship (ASP) and infection prevention (IP) programs, CDS interventions can play a crucial role in optimizing antibiotic prescribing practices, reducing healthcare-associated infections, and promoting diagnostic stewardship when optimally designed. This primer article aims to provide ASP and IP professionals with a practical framework for the development, design, and evaluation of CDS interventions.
Setting:
Large academic medical center design: Established frameworks of CDS evaluation, “Five Rights” of CDS and the “Ten Commandments of Effective Clinical Decision Support”, were applied to two real-world examples of CDS tools, a Vancomycin Best Practice Advisory and a Clostridioides Difficile order panel, to demonstrate a structured approach to developing and enhancing the functionality of ASP/IP CDS interventions to promote efficacy and reduce unintended consequences of CDS.
Conclusions:
By outlining a structured approach for the development and evaluation of CDS interventions, with focus on end user engagement, efficiency and feasibility, ASP and IP professionals can leverage CDS to enhance IP/ASP quality improvement initiatives aimed to improve antibiotic utilization, diagnostic stewardship, and adherence to IP protocols.
This paper analyses Italian party positions on the EU's response to the Russo-Ukrainian war, singling out the adoption of sanctions against Russia, the provision of military support to Kiev, enlargement to Ukraine and the welcoming of Ukrainian refugees into the Union's territory as the four main dimension of such a response. The paper draws on the literatures on cleavage politics, the inverted U curve and the differentiated forms of politicisation, thereby testing theory-driven research hypotheses through a qualitative content analysis of Italian parties' Facebook posts in the three months following the outbreak of the conflict, combining an inductive and a deductive approach. The findings show that party families are a good explanatory factor behind Italian party positions vis-à-vis the EU's response to the war outbreak as parties belonging to the same family shared a similar stance on the four dimensions of such a response. On the contrary, the Europeanism/Euroscepticism divide does not explain Italian party positions on the EU's reaction to the Ukrainian conflict as Europeanist parties split over the EU's provision of weapons to Ukraine about as much as Eurosceptic partis split over the adoption of sanctions against Moscow. Finally, the paper shows that policy issues in the EU's response to the war (such as sanctions and arms delivery) were much more salient for and contested by Italian political parties than constitutive issues (such as enlargement and asylum).
The boundary-layer stability on a section of a rotating wind turbine blade with an FFA-W3 series aerofoil at a chord Reynolds number of $3 \times 10^5$, with varying rotation and radii, is studied with direct numerical simulations and linear stability analyses. Low rotation does not significantly affect transition in the outboard blade region. The relative insensitivity to rotation is due to a laminar separation bubble near the leading edge, spanwise-deformed by a primary self-excited instability, promoting the secondary absolute instability of the Kelvin–Helmholtz (KH) vortices and rapid transition. Moderate increases in rotation, or moving inboard, stabilise the flow by accelerating the attached boundary layer and possibly inducing competition between cross-flow and KH modes. This delays separation and transition. Initially, for high rotation rates or radial locations close to the hub, transition is delayed. Nevertheless, strong stationary and travelling cross-flow modes are eventually triggered, spanwise modulating the KH rolls and shifting the transition line close to the leading edge. Cross-flow velocities as high as $56\,\%$ of the free stream velocity directed towards the blade tip are reached at the transition location. For radial locations farther from the hub, the effective angle of attack is decreased, and cross-flow transition occurs at lower rotation rates. The advance or delay of the transition line compared with a non-rotating configuration depends on the competing rotation effects of stabilising the attached boundary layer and triggering cross-flow modes in the separation flow region.
This introductory chapter examines arguments for and against adopting the All-Affected Principle (AAP) as a criterion for democratic inclusion, and the alternatives. For many, the attraction of the AAP lies in its straightforward simplicity: If you are affected by a collective decision, you should be able to influence it. Yet there remains sharp disagreement among scholars of democracy about how to best formulate the AAP and the circumstances in which it applies. Surveying the literature, we argue that appeals to the AAP will vary according to: (1) organizational scope; (2) decision-making context; (3) kinds of influence; (4) how influence is allocated; (5) the definition of “affectedness”; and (6) the stringency of any participatory requirements. Whether the AAP is consistent with existing arrangements, or requires a more radical redrawing of democratic boundaries, is a question on which opinions may differ significantly. We conclude by discussing the trade-offs between more versus less ambitious versions of the AAP, the implications for addressing pressing governance challenges, and the future of the democratic project more generally.