This article explores and discusses the change processes and pedagogical dilemmas ignited by introducing wild pedagogies to pedagogical employees in Danish early childhood institutions. By analysing experiments aimed at developing new play and learning environments, carried out as part of a large design-based research project, we discuss how existing “roots” of early childhood education in Denmark provide a fertile soil for the introduction of wild pedagogies. We identify two “shoots of change” with a potential for pushing the status quo in relations between children, adults, and more-than-human nature. Centreing on altering the place of nature in early childhood education and carving out time for more open approaches, these shoots are in close dialogue with wild pedagogies. By experimenting with these shoots of change, pedagogical dilemmas became more visible, important, and present to the participants. Attending to and exploring such dilemmas are crucial aspects of keeping socio-cultural change processes in motion.

Fast glacier motion is facilitated by slip at the ice-bed interface. For slip over rigid beds, areas of ice-bed separation (cavities) can exert significant control on slip dynamics. Analytic models of these systems assume that cavities instantaneously adjust to changes in slip and effective pressure forcings, but recent studies indicate transient forcings violate this—and other—underlying assumptions. To assess these incongruities, we conducted novel experiments emulating hard-bedded slip with ice-bed separation under periodic effective pressure transients. We slid an ice-ring over a sinusoidal bed while varying the applied overburden stress to emulate subglacial effective pressure cycles observed in nature and continuously recorded mechanical and geometric system responses. We observed characteristic lags and nonlinearities in system responses that were sensitive to forcing periodicity and trajectory. This gave rise to hysteresis not predicted in analytic theory, which we ascribed to a combination of geometric, thermal and rheologic processes. This framework corroborates other studies of transient glacier slip and we used it to place new constraints on transient phenomena observed in the field. Despite these divergences, average system responses converged toward model predictions, suggesting that analytic theory remains applicable for modeling longer-term behaviors of transiently forced slip with ice-bed separation.

Mild-to-moderate iodine deficiency remains a problem worldwide, including in Norway. Of particular, concern is fertile, pregnant and lactating women. The Norwegian Dairy Council developed a digital iodine-specific dietary screener (I-screener) for the assessment of iodine intake levels but has yet to be validated. The aim was thus to investigate the relative validity of the I-screener by comparing estimates of iodine intake from the I-screener against a single 24-hour recall (24HR) and urinary iodine concentration (UIC) in fertile women. Healthy females were recruited in Bergen in August–December 2021. Six spot-urine samples from six consecutive days were collected into a pooled sample to assess UIC. Each participant completed a single administration of the I-screener and the 24HR. The estimated daily iodine intake from the I-screener was compared with the estimations from the 24HR and UIC. Seventy-two women aged 19–39 completed the study. The median UIC was 76 μg/l. Compared with the 24HR, the I-screener placed 83 % of the participants in the same/adjacent tertial, with a slight agreement between the methods (Cohen's kappa = 0⋅187). The present study shows an acceptable correlation between the I-screener and the 24HR (r = 0⋅318), but not between the I-screener and UIC (r = 0⋅122). Despite its varying iodine estimate abilities, the I-screener may be used as an initial screening tool to rank fertile women on an individual level into deficient inadequate, and sufficient iodine intake. However, due to the relatively high risk of misclassification, further assessment of iodine status should follow.

Small quantities of liquid water lining triple junctions in polycrystalline glacier ice form connected vein networks that enable material exchange with underlying basal environments. Diffuse debris concentrations commonly observed in ice marginal regions might be attributed to this mechanism. Following recent cryogenic ring-shear experiments, we observed emplacement along grain boundaries of loess particles several tens of microns in size. Here, we describe an idealized model of vein liquid flow to elucidate conditions favoring such particle transport. Gradients in liquid potential drive flow toward colder temperatures and lower solute concentrations, while deviations of the ice stress state from hydrostatic balance produce additional suction toward anomalously low ice pressures. Our model predicts particle entrainment following both modest warming along the basal interface resulting from anticipated natural changes in effective stress, and the interior relaxation of temperature and solute concentration imposed by our experimental protocols. Comparisons with experimental observations are encouraging, but suggest that liquid flow rates are somewhat higher and/or more effective at dragging larger particles than predicted by our idealized model with nominal parameter choices. Diffuse debris entrainment extending several meters above the glacier bed likely requires a more sophisticated treatment that incorporates effects of ice deformation or other processes.

Textbook recommendations for gavaging rats vary between 1-5 ml for an adult rat. Rats weighing either 130 g or 250 g were gavaged with varying dosages of barium sulphate (BaSO4). After dosing, radiographs were taken at 0, 15 and 60 min. Animals showing a section of the small intestine totally filled with BaSO4 were scored as displaying spontaneous release. Other rats of the same sizes were gavaged with similar doses and subsequently tested in an open-field arena for behavioural abnormalities that might indicate stress or pain resulting from the procedure. Body temperature before and after treatment was recorded using microchip transponders. None of the 250 g rats in the 1 ml dosage group showed spontaneous release through the pyloric sphincter. In the 2 ml and 4 ml dosage groups, only one out of five animals showed spontaneous release. In the 6 ml dosage group, half of the animals showed spontaneous release. In the 8 ml and 10 ml dosage groups, five out of six and four out of five, respectively, showed spontaneous release. If doses were higher than 12 ml, no animal was able to keep all of the BaSO4 in its stomach. In the rats weighing 130 g, the 3 ml dosage group showed only one out of four rats with spontaneous release, whereas in the 5 ml and 7 ml dosage groups, all animals showed spontaneous release. After 15 min, all of the rats in both weight groups showed BaSO4 in the duodenum. Ambulation, rearing up onto the hind legs and defecation, as well as body temperature immediately after dosing, correlated very strongly with the dose (ml kg−1); increasing the dose resulted in reduced ambulation, rearing, defecation and body temperature. However, 10 min after performance of the open-field test, neither body temperature, serum corticosterone nor serum glucose showed any correlation with dose. This study indicates that high doses (ie doses up to 10 ml for a 250 g rat) might be safe to use; however, if an adverse impact on the rat is to be avoided, use of much lower doses should be considered—for example, doses that do not enforce opening of the pyloric sphincter in any rat. This would be less than 4 ml kg−1 in a 250 g rat.

Various tools have been developed over previous years to study the welfare of laboratory animals. These include preference tests, which are commonly used to evaluate housing environments. Preference tests, however, have some pitfalls: they supply information only on the animals’ present preferences, and they allow the animal the choice only between the options offered. Other methods based upon the collection of clinico-chemical data require handling of the animals, which can be stressful in itself. An alternative may be to use telemetry to measure the changes in physiological parameters caused by different environmental conditions. The aim of this study was to use telemetry to evaluate the short-term impact of housing conditions on rodents. We monitored heart rate, blood pressure and body temperature in rats kept on three different types of flooring — bedding, grid floors and plastic floors. The study revealed significant differences in systolic and diastolic blood pressure, heart rate and body temperature between rats housed in the three conditions, indicating that both grid floors and plastic floors are more stressful for the animals than bedding. The observed differences did not diminish over the two-week observation period. The grid-floor housing induced elevations in blood pressure and heart rate. Blood pressure remained elevated even when the animals were returned to standard bedding, whereas the heart rate declined back to its original value immediately in response to this shift. This study shows that telemetry is a very effective tool but that it needs integrating with other methods: in addition, a greater understanding of the biological significance of the changes in cardiovascular parameters is required before the hypothesis that these changes represent an indication of distress can be accepted.

The welfare of transgenic animals is often not considered prior to their generation. However, we demonstrate here how a welfare risk assessment can be carried out before transgenic animals are created. We describe a risk assessment identifying potential welfare problems in transgenic pigs generated for future xeno-donation of organs. This assessment is based on currently available information concerning transgenic animal models in which one or more transgenes relevant to future xeno-donation have been inserted. The welfare risk assessment reveals that future xeno-donor pigs may have an increased tendency toward septicaemias, reduced fertility and/or impaired vision. The transgenic animal models used in generating hypotheses about the welfare of xeno-donor pigs can also assist in the testing of these hypotheses. To ensure high levels of welfare of transgenic animals, analogous risk assessments can be used to identify potential welfare problems during the early stages of the generation of new transgenic animals. Such assessments may form part of the basis on which licenses to generate new transgenic animals are granted to research groups.

Glacier motion responds dynamically to changing meltwater inputs, but the multi-decadal response of basal sliding to climate remains poorly constrained due to its sensitivity across multiple timescales. Observational records of glacier motion provide critical benchmarks to decode processes influencing glacier dynamics, but multi-decadal records that precede satellite observation and modern warming are rare. Here we present a record of motion in the ablation zone of Saskatchewan Glacier that spans seven decades. We combine in situ and remote-sensing observations to inform a first-order glacier flow model used to estimate the relative contributions of sliding and internal deformation on dynamics. We find a significant increase in basal sliding rates between melt-seasons in the 1950s and those in the 1990s and 2010s and explore three process-based explanations for this anomalous behavior: (i) the glacier surface steepened over seven decades, maintaining flow-driving stresses despite sustained thinning; (ii) the formation of a proglacial lake after 1955 may support elevated basal water pressures; and (iii) subglacial topography may cause dynamic responses specific to Saskatchewan Glacier. Although further constraints are necessary to ascertain which processes are of greatest importance for Saskatchewan Glacier's dynamic evolution, this record provides a benchmark for studies of multi-decadal glacier dynamics.

Maintenance is an essential aspect to keeping production facilities running and safe. However, without an overview of the maintenance impact on production, gaining clarification of the impact of maintenance is difficult. This paper introduces modularization of maintenance based on the dimensions of maintenance: physical, action, and process. The approach is applied in a case study where maintenance decisions are improved and faster than prior to the introduction of the modularized maintenance.

Preterm infants show postnatal deficits of long-chain polyunsaturated fatty acids (LCPUFAs) which are essential for adequate growth and neurodevelopment. Human milk is a primary source of fatty acids (FAs) for the preterm infant, and therefore, knowledge about milk FA levels is required to design appropriate supplementation strategies. Here, we expanded on our previous study (Nilsson et al., 2018, Acta Paediatrica, 107, 1020–1027) determining FA composition in milk obtained from mothers of extremely low gestational age (<28 weeks) infants on three occasions during lactation. There was a clear difference in FA composition in milk collected at Day 7 and milk collected at postmenstrual weeks (PMW) 32 or PMW 40. Notably, the proportion of LCPUFAs was low and declined significantly during milk maturation. These results strengthen previous data that the content of FAs required by the preterm infant is not supplied in sufficient amounts when the mother’s own milk is the sole source of these essential nutrients.

Severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2) led to a significant disease burden and disruptions in health systems. We describe the epidemiology and transmission characteristics of early coronavirus disease 2019 (COVID-19) cases in Bavaria, Germany. Cases were reverse transcription polymerase chain reaction (RT-PCR)-confirmed SARS-CoV-2 infections, reported from 20 January−19 March 2020. The incubation period was estimated using travel history and date of symptom onset. To estimate the serial interval, we identified pairs of index and secondary cases. By 19 March, 3546 cases were reported. A large proportion was exposed abroad (38%), causing further local transmission. Median incubation period of 256 cases with exposure abroad was 3.8 days (95%CI: 3.5–4.2). For 95% of infected individuals, symptom onset occurred within 10.3 days (95%CI: 9.1–11.8) after exposure. The median serial interval, using 53 pairs, was 3.5 days (95%CI: 3.0–4.2; mean: 3.9, s.d.: 2.2). Travellers returning to Germany had an important influence on the spread of SARS-CoV-2 infections in Bavaria in early 2020. Especially in times of low incidence, public health agencies should identify holiday destinations, and areas with ongoing local transmission, to monitor potential importation of SARS-CoV-2 infections. Travellers returning from areas with ongoing community transmission should be advised to quarantine to prevent re-introductions of COVID-19.