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It has been argued that the incidental and arbitrary use of gender markings for inanimate concepts in language may affect the conceptualization or semantics of those inanimate concepts. The present article sought to replicate the findings of a classic paper that made this argument. Konishi used the potency dimension of the semantic differential method as an implicit measure of perceived gender. He reported that words for inanimate concepts of masculine grammatical gender were rated as higher in potency than words for the same concepts that had feminine grammatical gender. Two preregistered replication studies are reported here. The first was a conceptual replication of Konishi’s study that was conducted with 240 bilingual native speakers of either German or Spanish. Included in the study was a follow-up with 120 monolingual native English speakers. This data was used to test whether the grammatical gender in the native languages of German and Spanish speakers affected their sense of the potency of common inanimate categories when tested in a second language (English) in which they were fluent and the nouns had no grammatical gender. A second version of the study was conducted in the native languages of Spanish and German speakers, as a closer attempt at a replication of Konishi’s original study. The results of both studies provided evidence against the grammatical-gender hypothesis. Bayesian tests of both studies strongly favored the null hypothesis that there were no grammatical gender effects on implicit measures of perceived potency.
Climate-change discourse is suffused with a profound sense of loss, amid accelerating ecological degradation. While some ecocritics consider the elegy an apt means of narrativizing these losses, others call for genres capable of moving beyond mourning. I argue that the Bildungsroman—which typically depicts a protagonist who undergoes a transformational journey following crisis and eventually comes to terms with the world—may narrativize the process of moving beyond climate grief and adapting to a changed world. I indicate a corpus of novels that may be termed “climate Bildungsromane,” which envision various transformations following climate grief. Through an analysis of one significant example, Jenni Fagan's The Sunlight Pilgrims, I explore climate Bildungsromane's tendency to narrate the journey from ecocatastrophe to adaptation through a fusion of modern scientific rationality with forms of belief and storytelling commonly considered premodern. I contemplate how and why this seeming paradox surfaces across cultural imaginings of journeys beyond climate grief.
In many classification problems, one often possesses external and/or internal information concerning the objects or units to be analyzed which makes it appropriate to impose constraints on the set of allowable classifications and their characteristics. CONCLUS, or CONstrained CLUStering, is a new methodology devised to perform constrained classification in either an overlapping or nonoverlapping (hierarchical or nonhierarchial) manner. This paper initially reviews the related classification literature. A discussion of the use of constraints in clustering problems is then presented. The CONCLUS model and algorithm are described in detail, as well as their flexibility for use in various applications. Monte Carlo results are presented for two synthetic data sets with appropriate discussion of the resulting implications. An illustration of CONCLUS is presented with respect to a sales territory design problem where the objects classified are various Forbes-500 companies. Finally, the discussion section highlights the main contribution of the paper and offers some areas for future research.
Fluid administration is one of the basic components in the management of neurosurgical patients. However, there is still debate on the ideal fluid. Issues related to adequate volume replacement and effects on the intracranial pressure persist. Studies have demonstrated the harmful effects of colloids over crystalloids. Normal saline has remained a fluid of choice but there is now emerging evidence that it, too, is not free of its harmful effects. Hypertonic saline has also been accepted by many practitioners, but its use and administration require close monitoring. There is now growing evidence on the use of balanced solutions for neurosurgical patients. However, this evidence comes from a small number of studies. Hemodynamic monitoring for fluid therapy in these patients is prudent as these patients are prone to hypovolemia. Dynamic parameters like stroke volume variance and pulse pressure variance are considered more reliable to monitor fluid therapy in comparison to static parameters. This chapter briefly covers various clinical situations in neurosciences with respect to fluid therapy and use of hemodynamic monitoring while providing fluid therapy and its effect on patient outcome.
Intracavitary brachytherapy (ICBT) is essential in managing locally advanced cervical cancer. Brachytherapy as a modality has the advantage of a higher dose to the tumour with a dose fall off at the periphery as per the inverse square law. The dose per fraction is much higher than external beam radiotherapy. So proper application and dosimetry are of paramount importance to reduce late toxicity.
Methods:
A retrospective analysis of 69 patients who underwent three ICBT applications of 7 Gray in each fraction was done. The factors under consideration were the type of pain management (spinal anaesthesia (SA) versus conscious sedation (CS)), the initial size of the disease (bulky and non-bulky) and subsequent fractions (first fraction versus third fraction). The dosimetric parameters analysed were the doses received by points A, B and P and that of the critical organs (bladder, rectum and sigmoid colon).
Results:
The dose received by critical organs was comparable concerning all the factors under consideration. The dose to point P on the left side was significantly lower in the CS group than in the SA group (p-value = 0·031). Also, the dose to point P on the right side was significantly lower in the third fraction compared with the first fraction (p-value = 0·016).
Conclusions:
ICBT under spinal anaesthesia resulted in a higher dose to the pelvic wall. The initial size of the tumour or the subsequent fractions does not significantly affect the dose received by critical organs.
Terminalia chebula Retz. is a multipurpose tree but the primary purpose of cultivating and raising this tree species is its fruits. Large sized fruits easily fetch higher prices in the national and global markets. The availability of superior germplasm is, however, restricted by its very low natural regeneration, poor germination capacity of the seeds, very little knowledge about its propagation techniques, long juvenile period for fruits production which is almost 15–20 years. The availability of superior germplasm and shortening of long juvenile period can be resolved by the adoption of various vegetative propagation techniques. In the present study, scions of T. chebula Retz. were grafted on three different rootstocks; T. chebula Retz., Terminalia bellirica Roxb. and Terminalia arjuna Bedd to standardize vegetative propagation techniques in T. chebula. The grafting and budding methods used were cleft grafting, side-veneer grafting and patch budding. The results revealed that out of all the propagation techniques evaluated under nursery conditions, cleft grafting was most promising. It showed better results on principal parameters like graft survival ratio (46.67) and graft take ratio (60.00). In case of rootstocks, T. arjuna performed well on most of the growth parameters. Hence, it is concluded that T. arjuna as a rootstock can be cleft grafted with T. chebula Retz. scion not only to obtain healthy plants with desired characteristics in a short time but also to conserve its germplasm.
We estimate the impact of subsequent droughts on the revenues of farmers in Ethiopia factoring in their adaptive capacity. We find that after the first drought, there is no significant difference in the revenue of the farmers who experienced a drought, as compared to those who did not. However, there is a loss in revenue after the second drought, specifically for those farmers that are endowed with less assets. This finding underscores that a rise in the frequency of extreme events and shocks can potentially have significant local distributional implications, with wealth as a major distinguishing factor.
African mustard (Brassica tournefortii Gouan), turnipweed [Rapistrum rugosum (L.) All.], and African turnipweed (Sisymbrium thellungii O.E. Schulz) are common broadleaf weeds in chickpea (Cicer arietinum L.) crops, particularly under dryland region conditions in eastern Australia. Information on crop yield losses and the seed production potential for these weeds in chickpea are limited. Field studies were conducted in the winter seasons of 2020 and 2021 in eastern Australia with different densities of the three weeds (B. tournefortii, R. rugosum, and S. thellungii) in chickpea. Based on the sigmoidal model, chickpea yield was reduced by 50% at 11 plants m−2 of B. tournefortii. Based on hyperbolic models, a 50% yield reduction of chickpea occurred at 5 and 25 plants m−2 of R. rugosum and S. thellungii, respectively. Based on the linear model, B. tournefortii, R. rugosum, and S. thellungii produced a maximum of 448,000, 206,700, and 869,400, seeds m−2, respectively. At chickpea harvest, the low seed retention (<55%) of B. tournefortii and S. thellungii suggests limited opportunities for harvest weed seed control, and the seed rain of these weeds may enrich the weed seedbank in the soil. At crop harvest, the seed retention of R. rugosum was found to be greater than 90%, suggesting that it is a suitable candidate for harvest weed seed control. This study demonstrated that R. rugosum could cause a greater reduction in chickpea yield compared with B. tournefortii and S. thellungii. Furthermore, restricting seed rain of B. tournefortii and S. thellungii by not allowing the plants to produce seeds is recommended to reduce their weed seedbanks in the soil. The information generated from this study could aid in strengthening integrated weed management in chickpea.
Previous classification systems of pars tensa retractions have not consistently incorporated ossicular erosion or the presence of cholesteatoma.
Objective
This study aimed to illustrate our classification of pars tensa retractions, which is more precise than previous systems, with aided use of the endoscope.
Methods
A retrospective study was carried out on 200 ears of 170 patients whose pars tensa retractions had been documented at a tertiary otological referral centre.
Results
A classification system was developed. Pars tensa retractions were divided into the following subcategories: grade 0, grade 1, grade 2a, grade 2b, grade 3a, grade 3b, grade 3c, grade 4a, grade 4b, grade 4c, grade 5a, grade 5b and grade 5c.
Conclusion
This classification system was able to accommodate all pars tensa retractions. The distribution of grades of pars tensa retractions was based on ossicular status and the presence or absence of cholesteatoma. It is therefore a more applicable, and functionally based system than previous alternatives.
Double-chambered right ventricle is a rare and progressive condition that is characterised by obstruction of the right ventricular tract. Double-chambered right ventricle is usually associated with ventricular septal defect. Early surgical intervention is recommended in patients with these defects. Based on this background, the present study aimed to review early and midterm outcomes of primary repair after double-chambered right ventricle.
Methods:
Between January 2014 and June 2021, 64 patients with a mean age of 13.42 ± 12.31 years underwent surgical repair for double-chambered right ventricle. The clinical outcomes of these patients were reviewed and assessed retrospectively.
Results:
An associated ventricular septal defect was present in all the recruited patients; 48 (75%) patients of sub-arterial type, 15 (23.4%) of perimembranous, and 1 (1.6%) patient of muscular type. The patients were followed up for a mean period of 46.73 ± 27.37 months. During their follow-up, a significant decrease in the mean pressure gradient from 62.33 ± 5.52 mmHg preoperatively to 15.73 ± 2.94 mmHg postoperatively was observed (p < 0.001). Notably, there were no hospital deaths.
Conclusions:
The development of double-chambered right ventricle in association with ventricular septal defect results in an increased pressure gradient within the right ventricle. The defect needs correction in a timely manner. In our experience, the surgical correction of double-chambered right ventricle is safe and shows excellent early and mid-term results.
This note corrects an error in the formula to obtain the Whittle index using the Sherman–Morrison formula in Akbarzadeh and Mahajan (2022). Also, some other minor typos are highlighted.
Volume 1 of The Cambridge History of Global Migrations documents the lives and experiences of everyday people through the lens of human movement and mobility from 1400 to 1800. Focusing on the most important typologies of preindustrial global migrations, this volume reveals how these movements transformed global paths of mobility, the impacts of which we still see in societies today. Case studies include those that arose from the demand for free, forced, and unfree labor, long- and short-distance trade, rural/urban displacement, religious mobility, and the rise of the number of refugees worldwide. With thirty chapters from leading experts in the field, this authoritative volume is an essential and detailed study of how migration shaped the nature of global human interactions before the age of modern globalization.
Buckwheat (Fagopyrum spp.) is an important crop in the high-altitude regions of the Northwest Indian Himalayas. The agro-climatic heterogeneity of this region offers a great deal of diversity in the agro-morphology of buckwheat species. In this study, a total of 61 accessions of Fagopyrum esculentum and Fagopyrum tataricum were characterized for 17 morphological (8 qualitative and 9 quantitative) traits. Significant differences (P < 0.0001) among all the traits were revealed by one-way analysis of variance. Further, significant phenotypic variability in both qualitative as well as quantitative traits was also observed. Both positive and negative correlations were observed between the traits of agronomic relevance. The principal component analysis (PCA) reveals about 69% variability among the first six components. The accessions were divided into two key clusters with numerous subclusters by considering the unweighted pair group method with arithmetic mean dendrogram. A cluster of 19 accessions was formed utilizing a PCA scatter plot indicating accessions with maximum values for important quality traits like plant height, leaf blade width, stem colour (red), primary branches, inflorescence length, flower colour (greenish-yellow), seed anthocyanin colour (green), seed shape (ovate) and seed weight. These accessions can be of vital significance for future buckwheat breeding programmes. The findings from the current study will form a favourable base for genetic resource management, improved cultivation and applications of buckwheat at the commercial level in the northwestern Himalayas of India.
Attic retraction pockets, classified by degree of invasion and erosion, are reconstructed here as outlined by attic retraction pocket grade.
Method
Attic retraction pocket grade, surgical management, subsequent conditions of tympanic membrane and middle ear, and improvement of air–bone gap pure tone average were recorded.
Results
Our management strategy, based on attic retraction pocket grade, was applied to 200 ears: 44 grade I ears had non-surgical management and 156 grade II–V ears had surgical management. All 200 ears were followed up for 36–240 months, showing only 1 attic retraction pocket reformation and 1 adhesive otitis media (complication rate of 1 per cent), and improved air–bone gaps (p < 0.05). An earlier series of 50 grade IV attic retraction pockets used atticotomy with epitympanic reconstruction. These showed attic retraction pocket recurrence or cholesteatoma onset in 34 ears (68 per cent). When these ears were revised per protocol, there was no evidence of cholesteatoma thereafter.
Conclusion
Reconstruction of the ossicles and scutal defect according to attic retraction pocket grade shows long-term stability of the tympanic membrane, middle ear and hearing.
OBJECTIVES/GOALS: Clinical tissue specimens are primarily destined for formalin fixed, paraffin embedded processing to create a basis for diagnosis by microscopic examination. Innovations in specimen processing are required to expand its availability for inclusion as the substrate in assays that can contribute to the further development of Precision Medicine. METHODS/STUDY POPULATION: Transurethral resection of bladder tumors were selected for testing based on availability and tissue composition. A wash step was used to generate daughter aliquots composed of dislodged cells and a solution with prior contact to the parent tissue. This wash step served two purposes: 1) reduce the amount of contaminating material from spreading to other cases, a problem known to be associated with this type of specimen; and 2) create aliquots from which additional informative data could be generated. These daughter aliquots were then examined to determine their value as a source for exosome profiling, metabolomic studies, molecular characterization and organoid development. The parent tissue was not compromised, was able to undergo conventional processing and yielded results equivalent to unwashed specimens. RESULTS/ANTICIPATED RESULTS: Exosomes secreted by the tumor cells were identified to be present in the daughter aliquots by a combination of their isolation using CD31 and detection of miR-21 expression. These exosomes were confirmed to be not related to fragmented cells from testing for beta-tubulin. A global/discovery-based approach using mass spectrometry provided insights into early characterization of metabolomic profiles present in these tumor cells. Ample amounts of high quality DNA (226 ng/ul concentrations; 11.3 ug total) were recovered from the dislodged, excess cells in the wash for molecular studies. Finally, from viable cells recovered in one of the daughter wash aliquots, the ability to grow organoids was proven to be possible and reproducible. DISCUSSION/SIGNIFICANCE: Based on these results, the value of the clinical specimen can be markedly expanded for utilization in research and possible clinical use without detracting from the parent tissue. This non-destructive, easy to adopt wash procedure can potentially lead to an influx of data that may ultimately prove useful in improving patient care.
We present multi-wavelength data and analysis, including new FUV AstroSat/UVIT observations of the spiral galaxy UGC 10420 ($z=0.032$), a member of the cluster Abell 2199. UGC 10420 is present on the edge of the X-ray emitting region of the cluster at a distance of ${\sim} 680$ kpc from the centre. The far-ultraviolet (FUV) data obtained by the AstroSat mission show intense knots of star formation on the leading edge of the galaxy, accompanied by a tail of the same on the diametrically opposite side. Our analysis shows that the images of the galaxy disc in the optical and mid-infrared are much smaller in size than that in the FUV. While the broadband optical colours of UGC 10420 are typical of a post-starburst galaxy, the star formation rate (SFR) derived from a UV-to-IR spectral energy distribution is at least a factor of nine higher than that expected for a star-forming field galaxy of similar mass at its redshift. A careful removal of the contribution of the diffuse intracluster gas shows that the significant diffuse X-ray emission associated with the interstellar medium of UGC 10420 has a temperature, $T_X = 0.24^{+0.09}_{-0.06}$ keV (0.4–2.0 keV) and luminosity, $L_X = 1.8\pm{0.9}\times 10^{40}$ erg s$^{-1}$, which are typical of the X-ray emission from late-type spiral galaxies. Two symmetrically placed X-ray hot spots are observed on either sides of an X-ray weak nucleus.
Our analysis favours a scenario where the interaction of a galaxy with the hot intracluster medium of the cluster, perturbs the gas in the galaxy causing starburst in the leading edge of the disc. On the other hand, the turbulence thus developed may also push some of the gas out of the disc. Interactions between the gas ejected from the galaxy and the intracluster medium can then locally trigger star formation in the wake of the galaxy experiencing ram-pressure stripping. Our data however does not rule out the possibility of a flyby encounter with a neighbouring galaxy, although no relevant candidates are observed in the vicinity of UGC 10420.
The term “blue justice” was coined in 2018 during the 3rd World Small-Scale Fisheries Congress. Since then, academic engagement with the concept has grown rapidly. This article reviews 5 years of blue justice scholarship and synthesizes some of the key perspectives, developments, and gaps. We then connect this literature to wider relevant debates by reviewing two key areas of research – first on blue injustices and second on grassroots resistance to these injustices. Much of the early scholarship on blue justice focused on injustices experienced by small-scale fishers in the context of the blue economy. In contrast, more recent writing and the empirical cases reviewed here suggest that intersecting forms of oppression render certain coastal individuals and groups vulnerable to blue injustices. These developments signal an expansion of the blue justice literature to a broader set of affected groups and underlying causes of injustice. Our review also suggests that while grassroots resistance efforts led by coastal communities have successfully stopped unfair exposure to environmental harms, preserved their livelihoods and ways of life, defended their culture and customary rights, renegotiated power distributions, and proposed alternative futures, these efforts have been underemphasized in the blue justice scholarship, and from marine and coastal literature more broadly. We conclude with some suggestions for understanding and supporting blue justice now and into the future.
Australian grain growers are showing interest in winter-planted sorghum to avoid heat and water stress during the grain-filling stage. Winter-planted sorghum may face competition from winter weeds, including sterile oats, and no herbicides are registered for controlling winter weeds in winter-planted sorghum. The objectives of this study were to (1) identify alternate herbicide options for sterile oats control in winter-sown imidazolinone (IMI)-resistant sorghum and (2) assess the crop injury levels due to herbicides. Sterile oats control with pendimethalin at 0.59 kg ai ha−1, trifluralin at 0.38 kg ai ha−1, and prosulfocarb + S-metolachlor at 2.3 kg ai ha−1 was poor (<30%). Atrazine at 2.7 kg ai ha−1, imazamox + imazapyr at 0.048 kg ai ha−1, and atrazine at 2.7 kg ai ha−1 followed by imazamox + imazapyr at 0.048 kg ai ha−1 reduced the sterile oats biomass by 93%, 96%, and 100% and increased yields by 116%, 136%, and 140%, respectively, compared with nontreated control. Pendimethalin at 0.59 kg ai ha−1 and trifluralin at 0.38 kg ai ha−1 caused phytotoxicity to the crop and gave similar yields to nontreated control. Triallate at 0.8 kg ai ha−1, pyroxasulfone at 0.1 kg ai ha−1, and terbuthylazine at 1.0 kg ai ha−1 provided moderate weed control (44% to 65%) and increased yields by 68%, 108%, and 80%, respectively, compared with nontreated control. This research identified herbicide treatments for the effective control of sterile oats in winter-sown IMI-resistant sorghum that could be used in rotations to reduce the reliance on single herbicide treatments.
The goal of this monograph is to develop Hopf theory in the setting of a real reflection arrangement. The central notion is that of a Coxeter bialgebra which generalizes the classical notion of a connected graded Hopf algebra. The authors also introduce the more structured notion of a Coxeter bimonoid and connect the two notions via a family of functors called Fock functors. These generalize similar functors connecting Hopf monoids in the category of Joyal species and connected graded Hopf algebras.
The building blocks of the theory are geometric objects associated to a reflection arrangement such as faces, flats, lunes, and their orbits under the action of the Coxeter group. A generalized notion of zeta and Möbius function play a fundamental role in all aspects of the theory, including exp-log correspondences and results such as the Poincarö–Birkhoff–Witt theorem. The Tits algebra and its invariant subalgebra also play key roles.
This monograph opens a new chapter in Coxeter theory as well as in Hopf theory, connecting the two. It also relates fruitfully to many other areas of mathematics such as discrete geometry, semigroup theory, associative algebras, algebraic Lie theory, operads, and category theory. It is carefully written, with effective use of tables, diagrams, pictures, and summaries. It will be of interest to students and researchers alike.
The goal of this monograph is to develop Hopf theory in the setting of a real reflection arrangement. The central notion is that of a Coxeter bialgebra which generalizes the classical notion of a connected graded Hopf algebra. The authors also introduce the more structured notion of a Coxeter bimonoid and connect the two notions via a family of functors called Fock functors. These generalize similar functors connecting Hopf monoids in the category of Joyal species and connected graded Hopf algebras.
The building blocks of the theory are geometric objects associated to a reflection arrangement such as faces, flats, lunes, and their orbits under the action of the Coxeter group. A generalized notion of zeta and Möbius function play a fundamental role in all aspects of the theory, including exp-log correspondences and results such as the Poincarö–Birkhoff–Witt theorem. The Tits algebra and its invariant subalgebra also play key roles.
This monograph opens a new chapter in Coxeter theory as well as in Hopf theory, connecting the two. It also relates fruitfully to many other areas of mathematics such as discrete geometry, semigroup theory, associative algebras, algebraic Lie theory, operads, and category theory. It is carefully written, with effective use of tables, diagrams, pictures, and summaries. It will be of interest to students and researchers alike.