Empirical evidence is provided that within the inertial sublayer (i.e. logarithmic region) of adiabatic turbulent flows over smooth walls, the skewness of the vertical-velocity component $S_w$ displays universal behaviour, being a positive constant and constrained within the range $S_w \approx 0.1\unicode{x2013}0.16$, regardless of flow configuration and Reynolds number. A theoretical model is then proposed to explain this behaviour, including the observed range of variations of $S_w$. The proposed model clarifies why $S_w$ cannot be predicted from down-gradient closure approximations routinely employed in large-scale meteorological and climate models. The proposed model also offers an alternative and implementable approach for such large-scale models.

Researchers often aim to assess whether repeated measures of an exposure are associated with repeated measures of an outcome. A question of particular interest is how associations between exposures and outcomes may differ over time. In other words, researchers may seek the best form of a temporal model. While several models are possible, researchers often consider a few key models. For example, researchers may hypothesize that an exposure measured during a sensitive period may be associated with repeated measures of the outcome over time. Alternatively, they may hypothesize that the exposure measured immediately before the current time period may be most strongly associated with the outcome at the current time. Finally, they may hypothesize that all prior exposures are important. Many analytic methods cannot compare and evaluate these alternative temporal models, perhaps because they make the restrictive assumption that the associations between exposures and outcomes remains constant over time. Instead, we provide a tutorial describing four temporal models that allow the associations between repeated measures of exposures and outcomes to vary, and showing how to test which temporal model is best supported by the data. By finding the best temporal model, developmental psychopathology researchers can find optimal windows for intervention.

Pregnancy is a time of increased vulnerability to psychopathology, yet limited work has investigated the extent to which variation in psychopathology during pregnancy is shared and unshared across syndromes and symptoms. Understanding the structure of psychopathology during pregnancy, including associations with childhood experiences, may elucidate risk and resilience factors that are transdiagnostic and/or specific to particular psychopathology phenotypes. Participants were 292 pregnant individuals assessed using multiple measures of psychopathology. Confirmatory factor analyses found evidence for a structure of psychopathology consistent with the Hierarchical Taxonomy of Psychopathology (HiTOP). A common transdiagnostic factor accounted for most variation in psychopathology, and both adverse and benevolent childhood experiences (ACEs and BCEs) were associated with this transdiagnostic factor. Furthermore, pregnancy-specific anxiety symptoms most closely reflected the dimension of Fear, which may suggest shared variation with manifestations of fear that are not pregnancy-specific. ACEs and BCEs also linked to specific prenatal psychopathology involving thought problems, detachment, and internalizing, externalizing, antagonistic, and antisocial behavior. These findings extend the dimensional and hierarchical HiTOP model to pregnant individuals and show how maternal childhood risk and resilience factors relate to common and specific forms of psychopathology during pregnancy as a period of enhanced vulnerability.

Preconception and prenatal stress impact fetal and infant development, and women of color are disproportionately exposed to sociocultural stressors like discrimination and acculturative stress. However, few studies examine links between mothers’ exposure to these stressors and offspring mental health, or possible mitigating factors. Using linear regression, we tested associations between prenatally assessed maternal acculturative stress and discrimination on infant negative emotionality among 113 Latinx/Hispanic, Asian American, Black, and Multiethnic mothers and their children. Additionally, we tested interactions between stressors and potential pre- and postnatal resilience-promoting factors: community cohesion, social support, communalism, and parenting self-efficacy. Discrimination and acculturative stress were related to more infant negative emotionality at approximately 12 months old (M = 12.6, SD = .75). In contrast, maternal report of parenting self-efficacy when infants were 6 months old was related to lower levels of infant negative emotionality. Further, higher levels of parenting self-efficacy mitigated the relation between acculturative stress and negative emotionality. Preconception and prenatal exposure to sociocultural stress may be a risk factor for poor offspring mental health. Maternal and child health researchers, policymakers, and practitioners should prioritize further understanding these relations, reducing exposure to sociocultural stressors, and promoting resilience.

The developmental origins of psychopathology begin before birth and perhaps even prior to conception. Understanding the intergenerational transmission of psychopathological risk is critical to identify sensitive windows for prevention and early intervention. Prior research demonstrates that maternal trauma history, typically assessed retrospectively, has adverse consequences for child socioemotional development. However, very few prospective studies of preconception trauma exist, and the role of preconception symptoms of posttraumatic stress disorder (PTSD) remains unknown. The current study prospectively evaluates whether maternal preconception PTSD symptoms predict early childhood negative affectivity, a key dimension of temperament and predictor of later psychopathology. One hundred and eighteen women were recruited following a birth and prior to conception of the study child and were followed until the study child was 3–5 years old. Higher maternal PTSD symptoms prior to conception predicted greater child negative affectivity, adjusting for concurrent maternal depressive symptoms and sociodemographic covariates. In exploratory analyses, we found that neither maternal prenatal nor postpartum depressive symptoms or perceived stress mediated this association. These findings add to a limited prospective literature, highlighting the importance of assessing the mental health of women prior to conception and providing interventions that can disrupt the intergenerational sequelae of trauma.

The prenatal period represents a critical time for brain growth and development. These rapid neurological advances render the fetus susceptible to various influences with life-long implications for mental health. Maternal distress signals are a dominant early life influence, contributing to birth outcomes and risk for offspring psychopathology. This prospective longitudinal study evaluated the association between prenatal maternal distress and infant white matter microstructure. Participants included a racially and socioeconomically diverse sample of 85 mother–infant dyads. Prenatal distress was assessed at 17 and 29 weeks’ gestational age (GA). Infant structural data were collected via diffusion tensor imaging (DTI) at 42–45 weeks’ postconceptional age. Findings demonstrated that higher prenatal maternal distress at 29 weeks’ GA was associated with increased fractional anisotropy, b = .283, t(64) = 2.319, p = .024, and with increased axial diffusivity, b = .254, t(64) = 2.067, p = .043, within the right anterior cingulate white matter tract. No other significant associations were found with prenatal distress exposure and tract fractional anisotropy or axial diffusivity at 29 weeks’ GA, or earlier in gestation.

This work investigates how turbulence in open-channel flows is altered by the passage of surface waves by using experimental data collected with laboratory tests in a large-scale flume facility, wherein waves followed a current. Flow velocity data were measured with a laser Doppler anemometer and used to compute profiles of mean velocity and Reynolds stresses, and pre-multiplied spectra. The velocity signal containing contributions from the mean flow, wave motion and turbulence was decomposed using the empirical mode decomposition (EMD), which is considered a promising tool for the analysis of velocity time series measured in complex flows. A novel outer length scale $h_{0}$ is proposed which separates the flow into two regions depending on the competition between the vertical velocities associated with the wave motion and the turbulent velocities imposed by the current. This outer length scale allows for the identification of a genuine overlap layer and an insightful scaling of turbulent statistics in the current-dominated flow region (i.e. $y/h_{0} < 1$). As the wave contribution to the vertical velocity increases, the pre-multiplied spectra reveal two intriguing features: (i) in the current-dominated flow region, the very large-scale motions (VLSMs) are progressively weakened but attached eddies are still present; and (ii) in the wave-dominated flow region (i.e. $y/h_{0} > 1$), a new spectral signature associated with long turbulent structures (approximately 6 and 25 times the flow depth $h$) appears. These longitudinal structures present in the wave-dominated flow region seem to share many features with Langumir-type cells.

Children exposed to prenatal maternal psychological distress are at elevated risk for a range of adverse outcomes; however, it remains poorly understood whether postnatal influences can ameliorate impairments related to prenatal distress. The current study evaluated if sensitivematernal care during the first postnatal year could mitigate child cognitive and emotional impairments associated with prenatal psychological distress. Prenatal maternal psychological distress was assessed via self-reports of anxiety, depression, and perceived stress for 136 mothers at five prenatal and four postpartum time points. Quality of maternal care (sensitivity to nondistress, positive regard, and intrusiveness reverse-scored) were assessed during a mother–child play interaction at 6 and 12 months. Child cognitive function and negative emotionality were assessed at 2 years, using The Bayley Scales and the Early Childhood Behavior Questionnaire. Elevated prenatal distress was associated with poorer child cognitive function and elevated negative emotionality. Children exposed to elevated prenatal maternal distress did not, however, display these outcomes if they received high-quality caregiving. Specifically, maternal care moderated the relation between prenatal psychological distress and child cognitive function and negative emotionality. This association remained after consideration of postnatal maternal psychological distress and relevant covariates. Sensitive maternal care was associated with altered offspring developmental trajectories, supporting child resilience following prenatal distress exposure.

The pregnancy period represents a unique window of opportunity to identify risks to both the fetus and mother and to deter the intergenerational transmission of adversity and mental health problems. Although the maternal–fetal dyad is especially vulnerable to the effects of stress during pregnancy, less is known about how the dyad is also receptive to salutary, resilience-promoting influences. The present review adopts life span and intergenerational perspectives to review four key areas of research. The first part describes how pregnancy is a sensitive period for both the mother and fetus. In the second part, the focus is on antecedents of maternal prenatal risks pertaining to prenatal stress response systems and mental health. The third part then turns to elucidating how these alterations in prenatal stress physiology and mental health problems may affect infant and child outcomes. The fourth part underscores how pregnancy is also a time of heightened fetal receptivity to maternal and environmental signals, with profound implications for adaptation. This section also reviews empirical evidence of promotive and protective factors that buffer the mother and fetus from developmental and adaptational problems and covers a sample of rigorous evidence-based prenatal interventions that prevent maladaptation in the maternal–fetal dyad before babies are born. Finally, recommendations elaborate on how to further strengthen understanding of pregnancy as a period of multilevel risk and resilience, enhance comprehensive prenatal screening, and expand on prenatal interventions to promote maternal–fetal adaptation before birth.

Associations between prenatal maternal psychological distress and offspring developmental outcomes are well documented, yet relatively little research has examined links between maternal distress and development in utero, prior to postpartum influences. Fetal heart rate (FHR) parameters are established indices of central and autonomic nervous system maturation and function which demonstrate continuity with postnatal outcomes. This prospective, longitudinal study of 149 maternal–fetal pairs evaluated associations between prenatal maternal distress, FHR parameters, and dimensions of infant temperament. Women reported their symptoms of psychological distress at five prenatal visits, and FHR monitoring was conducted at the last three visits. Maternal report of infant temperament was collected at 3 and 6 months of age. Exposure to elevated prenatal maternal psychological distress was associated with higher late-gestation resting mean FHR (FHRM) among female but not male fetuses. Higher late-gestation FHRM was associated with lower infant orienting/regulation and with higher infant negative affectivity, and these associations did not differ by infant sex. A path analysis identified higher FHRM as one pathway by which elevated prenatal maternal distress was associated with lower orienting/regulation among female infants. Findings suggest that, for females, elevated maternal distress alters fetal development, with implications for postnatal function. Results also support the notion that, for both sexes, individual differences in regulation emerge prenatally and are maintained into infancy. Collectively, these findings underscore the utility of direct assessment of development in utero when examining if prenatal experiences are carried forward into postnatal life.

The project “Social Point” deals in promoting integration of Mental Health Service recipients within contexts of social relationship, voluntary work and community activism. The project is still taking place in the district of Modena.

This paper investigates the existence and scaling of the so-called large-scale and very-large-scale motions (LSMs and VLSMs) in non-uniform turbulent open-channel flows developing over a smooth bed in a laboratory flume. A laser Doppler anemometry system was employed to measure vertical profiles of longitudinal and bed-normal velocity statistics over a wide range of hydraulic conditions. Pre-multiplied spectra of the longitudinal velocity fluctuations revealed the existence of two peaks occurring at wavelengths consistent with those associated with LSMs and VLSMs as detected in the past literature pertaining to wall turbulence. However, contrary to so-called canonical wall flows (i.e. flat-plate boundary layers, pipe and closed-channel flows), the LSM and VLSM peaks observed in the open-channel flows investigated herein are detectable over a much larger extent of the wall-normal coordinate. Furthermore, the VLSM peak appears at von Kármán numbers $Re_{\unicode[STIX]{x1D70F}}$ as low as 725, whereas in other wall flows much higher values are normally required. Finally, as conjectured by a recent study on uniform rough-bed open-channel flows, the present paper confirms that LSM wavelengths scale nicely with the flow depth, whereas the channel aspect ratio (i.e. the ratio between channel width and flow depth) is the non-dimensional parameter controlling the scaling of VLSM wavelengths. The intensity and wavelengths of the VLSM peaks were also observed to depend on the spanwise coordinate. This result suggests that VLSMs might be dynamically linked to secondary currents, as these are also known to vary in strength and size across the channel width.

Maternal depression is one of the most common prenatal complications, and prenatal maternal depression predicts many child psychopathologies. Here, we apply the fetal programming hypothesis as an organizational framework to address the possibility that fetal exposure to maternal depressive symptoms during pregnancy affects fetal development of vulnerabilities and risk mechanisms, which enhance risk for subsequent psychopathology. We consider four candidate pathways through which maternal prenatal depression may affect the propensity of offspring to develop later psychopathology across the life span: brain development, physiological stress regulation (hypothalamic–pituitary–adrenocortical axis), negative emotionality, and cognitive (effortful) control. The majority of past research has been correlational, so potential causal conclusions have been limited. We describe an ongoing experimental test of the fetal programming influence of prenatal maternal depressive symptoms using a randomized controlled trial design. In this randomized controlled trial, interpersonal psychotherapy is compared to enhanced usual care among distressed pregnant women to evaluate whether reducing prenatal maternal depressive symptoms has a salutary impact on child ontogenetic vulnerabilities and thereby reduces offspring's risk for emergence of later psychopathology.

The thermal behaviour and mechanism of formation of different texture types of intergrown As-Sb alloys have been studied by DTA and annealing experiments performed on natural samples. The constant composition of the As-rich component and of the stibarsen in the intergrowths, and the large compositional range of the homogeneous solid solution obtained after heating in the DTA cycle, have been established using the linear relationship between cell volume and composition. The high-temperature features detected in the DTA studies of the natural samples confirm previously published phase relations for the synthetic As-Sb system. The low-temperature features can be correlated with the homogenization reaction which leads to the formation of a complete solid solution. Study of TTT plots based on the annealing experiments clearly shows that a diffusion mechanism is involved in the homogenization reaction. This has been further substantiated by fitting the experimental data to kinetic equations for diffusion-controlled processes. The kinetic parameters evaluated from the ending time for the 520, 480, and 420 °C annealing experiments, using both the Arrhenius and the transition state theory formalisms, suggests a rather rigid activated complex for the rate-determining step of the process.

Hourly measurements of wind, temperature, and humidity were made between elevations of 1 and 20 m in the coastal area of Adélie Land over a period of 45 d in January and February 1978. About 1000 profiles are available.

The height of the constant flux layer is >5 m despite the influence of katabatic winds, the wind profile is logarithmic with a mean standard deviation from the logarithmic law of 15 mm s−1. The potential temperature profile is also logarithmic with a mean standard deviation of 0.04°C. The most important deviation from the logarithmic law appears between -4 and 0°C.

Humidity was measured at two points only, between 1 and 20 m; the mean gradient was about 0.01 mbar m−1 and the flux of latent heat was generally negligible.

Net radiation was measured for only 10 d because of radiometer failure. All the fluxes are calculated using data for the 5 m layer. For the 10 d period, the heat loss was about 3 Wm−2 with a mean heat flux of -27.5 Wm−2 and mean net radiation of -10.5 Wm−2(the minus sign signifying the flux is towards the surface). In general, the heat flux is towards the surface (92% of the cases) but is away from the surface in the afternoon. The ablation during the 10 d period without snow-fall was about 200 mm of ice.