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Persons with mental illnesses may experience stigma from their immediate family members in addition to other forms of stigma. Using semi-structured interviews, we investigated experiences of familial mental illness stigma among 15 people diagnosed with mental illnesses in a mid-sized city in Canada. We identified five themes that speak to participants’ experiences of familial mental illness stigma and ways to reduce it. The themes include the following: diagnosis as a ‘double-edged sword,’ potential familial isolation, familial stigma as societal stigma localized, stories of acceptance, and confronting potential familial mental illness stigma. Participants’ narratives indicate that familial mental illness stigma is rooted in the broader social or public stigma, which sees its way into familial relations as well. This stigma takes various forms, including relationship bias or unfair treatment, breakdown in romantic relationships, loss of status, verbal and emotional abuse, exclusion from decision-making, and alienation within their immediate and extended families. Familial mental illness stigma experiences negatively impact participant’s psychological well-being and personal empowerment. However, participants also shared ways that family members create supportive environments or actively confront or prevent stigma. Overall, this study has contributed to knowledge on mental illness stigma, particularly familial mental illness stigma from the perspective of participants living with a mental illness in a high-income country. Suggestions for future research include a focus on strategies to prevent ongoing familial mental illness stigma and large-scale studies to explore familial mental illness stigma to understand why families might perpetrate stigma.
Various strategies to suppress the Coronavirus have been adopted by governments across the world; one such strategy is diagnostic testing. The anxiety of testing on individuals is difficult to quantify. This analysis explores the use of soft intelligence from Twitter (USA, UK & India) in helping better understand this issue.
Methods
A total of 650,000 tweets were collected between September and October 2020, using Twitter API using hashtags such as ‘#oxymeter’, ‘#oximeter’, ‘#antibodytest’, ‘#infraredthermometer’, ‘#swabtest’, ‘#rapidtest’, and ‘#antigen’. We applied natural language processing (TextBlob) to assign sentiment and categorize the tweets by emotions and attitude. WordCloud was then used to identify the single topmost 500 words in the whole tweet dataset.
Results
Global analysis and pre-processing of the tweets indicate that 21 percent, seven percent and four percent of tweets originated from the USA, UK, and India respectively. The tweets from #antibody, #rapid, #antigen, and #swabtest were positive sentiments, whereas #oxymeter, #infraredthermometer were mostly neutral. The underlying emotions of the tweets were approximately 2.5 times more positive than negative. The most used words in the tweets included ‘hope’ ‘insurance’, ‘symptoms’, ‘love’, ‘painful’, ‘cough’, ‘fast test’, ‘wife’, and ‘kids’.
Conclusions
The finding suggests that it may be reasonable to infer that people are generally concerned about their personal and social wellbeing, wanting to keep themselves safe and perceive testing to deliver some component of that feeling of safety. There are several limitations to this study such as it was restricted to only three countries, and includes only English language tweets with a limited number of hashtags.
To examine cross-sectional associations between farmers’ market shopping behaviours and objectively measured and self-reported fruit and vegetable (FV) intake among rural North Carolina (NC) and New York City (NYC) shoppers.
Design:
Cross-sectional intercept surveys were used to assess self-reported FV intake and three measures of farmers’ market shopping behaviour: (1) frequency of purchasing FV; (2) variety of FV purchased and (3) dollars spent on FV. Skin carotenoids, a non-invasive biomarker for FV intake, were objectively measured using pressure-mediated reflection spectroscopy. Associations between farmers’ market shopping behaviours and FV intake were examined using regression models that controlled for demographic variables (e.g. age, sex, race, smoking status, education, income and state).
Setting:
Farmers’ markets (n 17 markets) in rural NC and NYC.
Participants:
A convenience sample of 645 farmers’ market shoppers.
Results:
Farmers’ market shoppers in NYC purchased a greater variety of FV and had higher skin carotenoid scores compared with shoppers in rural NC. Among all shoppers, there was a positive, statistically significant association between self-reported frequency of shopping at farmers’ markets and self-reported as well as objectively assessed FV intake. The variety of FV purchased and farmers’ market spending on FV also were positively associated with self-reported FV intake, but not skin carotenoids.
Conclusion:
Those who shop for FV more frequently at a farmers’ markets, purchase a greater variety of FV and spend more money on FV have higher self-reported, and in some cases higher objectively measured FV intake. Further research is needed to understand these associations and test causality.
ABSTRACT IMPACT: Identifying factors associated with opioid overdoses will enable better resource allocation in communities most impacted by the overdose epidemic. OBJECTIVES/GOALS: Opioid overdoses often occur in hotspots identified by geographic and temporal trends. This study uses principles of community engaged research to identify neighborhood and community-level factors associated with opioid overdose within overdose hotspots which can be targets for novel intervention design. METHODS/STUDY POPULATION: We conducted an environmental scan in three overdose hotspots’‘ two in an urban center and one in a small city’‘ identified by the Rhode Island Department of Health as having the highest opioid overdose burden in Rhode Island. We engaged hotspot community stakeholders to identify neighborhood factors to map within each hotspot. Locations of addiction treatment, public transportation, harm reduction programs, public facilities (i.e., libraries, parks), first responders, and social services agencies were converted to latitude and longitude and mapped in ArcGIS. Using Esri Service Areas, we will evaluate the service areas of stationary services. We will overlay overdose events and use logistic regression identify neighborhood factors associated with overdose by comparing hotspot and non-hotspot neighborhoods. RESULTS/ANTICIPATED RESULTS: We anticipate that there will be differing neighborhood characteristics associated with overdose events in the densely populated urban area and those in the smaller city. The urban area hotspots will have overlapping social services, addiction treatment, and transportation service areas, while the small city will have fewer community resources without overlapping service areas and reduced public transportation access. We anticipate that overdoses will occur during times of the day when services are not available. Overall, overdose hotspots will be associated with increased census block level unemployment, homelessness, vacant housing, and low food security. DISCUSSION/SIGNIFICANCE OF FINDINGS: Identifying factors associated with opioid overdoses will enable better resource allocation in communities most impacted by the overdose epidemic. Study results will be used for novel intervention design to prevent opioid overdose deaths in communities with high burden of opioid overdose.
Insular species, particularly birds, experience high levels of speciation and endemism. Similarly, island birds experience extreme levels of extinction. Based on a 2012 taxonomic assessment, historically there were four reed-warbler species in the Mariana Islands, the Guam Reed-warbler Acrocephalus luscinia (Guam), the Nightingale Reed-warbler Acrocephalus hiwae (Saipan and Alamagan), the Aguijuan Reed-warbler A. nijoi (Aguiguan or Aguijuan), and the Pagan Reed-warbler A. yamashinae (Pagan). Between 2008 and 2010 we surveyed for three of these species on Alamagan, Aguiguan, and Pagan. Our results indicate that reed-warblers are extinct on Aguiguan, likely extinct on Pagan, and only the Nightingale Reed-warbler on Alamagan and Saipan remains. We estimated the global population at between 1,019 and 6,356 birds (95% CI; mean estimate 3,688), which has declined by more than 1,000 birds since the first quantitative surveys were conducted in 1982, i.e. a 24% decline in 28 years. Camp et al. (2009) describe the status of the Nightingale Reed-warbler on Saipan, which has also declined. We estimated the Alamagan population to be between 428 and 1,762 birds in 2010 (mean estimate 946). Thus, the Alamagan population is ~25 % of the global population, and it has declined slightly since 2000. This decline was not significant but is concerning, especially given a similar decline on Saipan. Restoration and protection of tall-stature native and secondary forest could benefit the Alamagan population, as would similar conservation on Saipan that includes wetland habitat. After suitable restoration of forest and wetland habitats on Aguiguan, Guam and Pagan, individuals from Alamagan and Saipan could serve as founder populations. Careful consideration of the extent and habitat preference of individuals translocated to Tinian, where an unknown reed-warbler species previously occurred, is warranted.
Genotype-first and within-family studies can elucidate factors that contribute to psychiatric illness. Combining these approaches, we investigated the patterns of influence of parental scores, a high-impact variant, and schizophrenia on dimensional neurobehavioral phenotypes implicated in major psychiatric disorders.
Methods
We quantitatively assessed cognitive (FSIQ, VIQ, PIQ), social, and motor functioning in 82 adult individuals with a de novo 22q11.2 deletion (22 with schizophrenia), and 148 of their unaffected parents. We calculated within-family correlations and effect sizes of the 22q11.2 deletion and schizophrenia, and used linear regressions to assess contributions to neurobehavioral measures.
Results
Proband-parent intra-class correlations (ICC) were significant for cognitive measures (e.g. FSIQ ICC = 0.549, p < 0.0001), but not for social or motor measures. Compared to biparental scores, the 22q11.2 deletion conferred significant impairments for all phenotypes assessed (effect sizes −1.39 to −2.07 s.d.), strongest for PIQ. There were further decrements in those with schizophrenia. Regression models explained up to 37.7% of the variance in IQ and indicated that for proband IQ, parental IQ had larger effects than schizophrenia.
Conclusions
This study, for the first time, disentangles the impact of a high-impact variant from the modifying effects of parental scores and schizophrenia on relevant neurobehavioral phenotypes. The robust proband-parent correlations for cognitive measures, independent of the impact of the 22q11.2 deletion and of schizophrenia, suggest that, for certain phenotypes, shared genetic variation plays a significant role in expression. Molecular genetic and predictor studies are needed to elucidate shared factors and their contribution to psychiatric illness in this and other high-risk groups.
Healthcare personnel (HCP) were recruited to provide serum samples, which were tested for antibodies against Ebola or Lassa virus to evaluate for asymptomatic seroconversion.
Setting:
From 2014 to 2016, 4 patients with Ebola virus disease (EVD) and 1 patient with Lassa fever (LF) were treated in the Serious Communicable Diseases Unit (SCDU) at Emory University Hospital. Strict infection control and clinical biosafety practices were implemented to prevent nosocomial transmission of EVD or LF to HCP.
Participants:
All personnel who entered the SCDU who were required to measure their temperatures and complete a symptom questionnaire twice daily were eligible.
Results:
No employee developed symptomatic EVD or LF. EVD and LF antibody studies were performed on sera samples from 42 HCP. The 6 participants who had received investigational vaccination with a chimpanzee adenovirus type 3 vectored Ebola glycoprotein vaccine had high antibody titers to Ebola glycoprotein, but none had a response to Ebola nucleoprotein or VP40, or a response to LF antigens.
Conclusions:
Patients infected with filoviruses and arenaviruses can be managed successfully without causing occupation-related symptomatic or asymptomatic infections. Meticulous attention to infection control and clinical biosafety practices by highly motivated, trained staff is critical to the safe care of patients with an infection from a special pathogen.
The north-west European population of Bewick’s Swan Cygnus columbianus bewickii declined by 38% between 1995 and 2010 and is listed as ‘Endangered’ on the European Red List of birds. Here, we combined information on food resources within the landscape with long-term data on swan numbers, habitat use, behaviour and two complementary measures of body condition, to examine whether changes in food type and availability have influenced the Bewick’s Swan’s use of their main wintering site in the UK, the Ouse Washes and surrounding fens. Maximum number of Bewick’s Swans rose from 620 in winter 1958/59 to a high of 7,491 in winter 2004/05, before falling to 1,073 birds in winter 2013/14. Between winters 1958/59 and 2014/15 the Ouse Washes supported between 0.5 and 37.9 % of the total population wintering in north-west Europe (mean ± 95 % CI = 18.1 ± 2.4 %). Swans fed on agricultural crops, shifting from post-harvest remains of root crops (e.g. sugar beet and potatoes) in November and December to winter-sown cereals (e.g. wheat) in January and February. Inter-annual variation in the area cultivated for these crops did not result in changes in the peak numbers of swans occurring on the Ouse Washes. Behavioural and body condition data indicated that food supplies on the Ouse Washes and surrounding fens remain adequate to allow the birds to gain and maintain good body condition throughout winter with no increase in foraging effort. Our findings suggest that the recent decline in numbers of Bewick’s Swans at this internationally important site was not linked to inadequate food resources.
Ira Aldridge -- a black New Yorker -- was one of nineteenth-century Europe's greatest actors. He performed abroad for forty-three years, winning more awards, honors, and official decorations than any of his professional peers. Billed as the "African Roscius," Aldridge developed a repertoire initially consisting of Shakespeare's Othello, melodramas about slavery, and farces that drew on his ability to sing and dance. By the time he began touring in Europe he was principally a Shakespearean actor, playing such classic characters as Shylock, Macbeth, Richard III, and King Lear. Although his frequent public appearances made him the most visible black man in the world by mid-nineteenth century, today Aldridge tends to be a forgotten figure, seldom mentioned in histories of British and European theater. This collection restores the luster to Aldridge's reputation by examining his extraordinary achievements against all odds. The early essays offer biographical information, while later essays examine his critical and popular reception throughout the world. Taken together, these diverse approaches to Aldridge offer a fuller understanding and heightened appreciation of a remarkable man who had an exceptionally interesting life and a spectacular career. Contributors: Cyril Bruyn Andrews, Nikola Batusic, Philip A. Bell, Keith Byerman, Ruth M. Cowhig, Nicholas M. Evans, Joost Groeneboer, Ann Marie Koller, Joyce Green MacDonald, Herbert Marshall, James J. Napier, Krzysztof Sawala, Gunner Sjögren, James McCune Smith, Hazel Waters, and Stanley B. Winters.
Bernth Lindfors is Professor Emeritus of English and African literatures at The University of Texas at Austin.
Ion-chemistry and sulphate-isotope values for snow samples from the Prince of Wales Icefield, Ellesmere Island, Canada, show distinct seasonal trends and spatial patterns. Sixteen surface snow samples from two transects, and 30 samples from five depth profiles, representing fall 2003 to spring 2004 accumulation, have been analyzed. Surface snow samples show decreasing SO42– and Na+ concentrations along with decreasing δ34S values with distance inland and increased elevation. These trends follow an expected pattern of decreasing sea-salt aerosol impact with greater vertical and horizontal distance from sea-water sources. Depth-profile total sulphate and non-sea-salt sulphate increase in concentration with height in the snowpack, and these results, combined with δ34S values that are more positive in fall snow, are consistent with increased amounts of anthropogenic sulphate in surface spring snow. Sulphate apportionment was performed on surface snow assuming an isotopically light sulphate source (anthropogenic plus volcanic) mixed with isotopically heavier sulphate from dimethylsulphide (DMS) oxidation and sea water. Isotopically light sulphate in surface snow was apparent at all elevations at a reasonably uniform concentration. DMS sulphate, however, decreased exponentially with altitude, reflecting an ocean level source with oxidation occurring during transport and deposition. The significance to multi-year deposition studies is that sulphate from DMS oxidation may be related to sea-ice conditions in the region.
The purpose of this study is to identify characterize and quantify local, regional and remote effects of snow cover on western U. S. climate and water resources. An ensemble of predictability and sensitivity studies was made with the U.S. National Center for Atmospheric Research (NCAR) Community Climate Model, version 3 (CCM3) to investigate the relative roles of snow-cover anomalies and initial atmospheric states in the subsequent accumulation and ablation seasons. The suite of model experiments focuses on the direct effect of snow on regional climate anomalies and ultimately will be used to examine the lagged effect of anomalous snow cover on the climate. The set of ensemble simulations presented here looks at the climate-system response to anomalously high and low snow cover at the start of the ablation season over the western U.S.A. These current results suggest that the initial state of snow cover is more important than the initial state of the atmosphere or of sea-surface temperatures because of direct thermal effects on the surface and subsequent indirect, dynamical effects on the atmospheric circulation.
In the United States alone, ∼14,000 children are hospitalised annually with acute heart failure. The science and art of caring for these patients continues to evolve. The International Pediatric Heart Failure Summit of Johns Hopkins All Children’s Heart Institute was held on February 4 and 5, 2015. The 2015 International Pediatric Heart Failure Summit of Johns Hopkins All Children’s Heart Institute was funded through the Andrews/Daicoff Cardiovascular Program Endowment, a philanthropic collaboration between All Children’s Hospital and the Morsani College of Medicine at the University of South Florida (USF). Sponsored by All Children’s Hospital Andrews/Daicoff Cardiovascular Program, the International Pediatric Heart Failure Summit assembled leaders in clinical and scientific disciplines related to paediatric heart failure and created a multi-disciplinary “think-tank”. The purpose of this manuscript is to summarise the lessons from the 2015 International Pediatric Heart Failure Summit of Johns Hopkins All Children’s Heart Institute, to describe the “state of the art” of the treatment of paediatric cardiac failure, and to discuss future directions for research in the domain of paediatric cardiac failure.
The above article from Management and Organization Review, published online 7 SEP 2011, has been retracted by agreement between the authors, the journal's outgoing Editor-in-Chief Anne Tsui, the journal's incoming Editor-in-Chief Arie Y. Lewin, and John Wiley & Sons Asia Pty Ltd. The retraction has been agreed due to unattributed overlap with work previously published in Academy of Management Review, 34(4): 586–591: ‘Editor's comments: The better angels of our nature – Ethics and integrity in publishing process’ by Marshall Schminke. The editors and authors joindy wrote a letter, available below, to explain the process used to come to the retraction decision.
The purpose of this letter is to explain the circumstances and reasons for the retraction of the paper ‘Ethics and integrity of the publishing process: Myths, facts, and a roadmap’ by Schminke and Ambrose in Management and Organization Review (MOR), Volume 7 issue 3, pages 397 to 406, November 2011.
Retraction of a published paper due to self-plagiarism is an unpleasant if not painful experience for both journal editors and authors. Self-plagiarism means that authors have used materials in another paper (whether published or in working paper format) without attributing the source of the materials or ideas. In this instance, the materials being self-plagiarized are from an earlier editorial written by the lead author. Self-plagiarism is in violation of publication ethics, according to the Committee of Publication Ethics' guidelines on suspected plagiarism (http://publicationethics.org/files/u7140/plagiarism%20B_0.pdf).
The island of Aguiguan is part of the Mariana archipelago and currently supports populations of four endemic species, including one endemic genus, Cleptornis. Bird population trends since 1982 were recently assessed on the neighbouring islands of Saipan, Tinian, and Rota indicating declines in some native species. Point-transect surveys were conducted in 2008 by the U.S. Fish and Wildlife Service to assess population densities and trends on Aguiguan. Densities for six of the nine native birds—White-throated Ground-dove Gallicolumba xanthonura, Collared Kingfisher Todiramphus chloris, Rufous Fantail Rhipidura rufifrons, Golden White-eye Cleptornis marchei, Bridled White-eye Zosterops conspicillatus and Micronesian Starling Aplonis opaca—and the non-native bird—Island Collared-dove Streptopelia bitorquata—were significantly greater in 2008 than in 1982. No differences in densities were detected among the surveys for Mariana Fruit-dove Ptilinopus roseicapilla, and Micronesian Myzomela Myzomela rubratra. Three federally and locally listed endangered birds—Nightingale Reed-warbler Acrocephalus luscinius, Mariana Swiftlet Collocalia bartschi, and Micronesian Megapode Megapodius laperous)—were either not detected during the point-transect counts, the surveys were not appropriate for the species, or the numbers of birds detected were too small to estimate densities. The factors behind the increasing trends for some species are unknown but may be related to increased forest cover on the island since 1982. With declining trends for some native species on neighbouring islands, the increasing and stable trends on Aguiguan is good news for forest bird populations in the region, as Aguiguan populations can help support conservation efforts on other islands in the archipelago.
To examine the use of vitamin D supplements during infancy among the participants in an international infant feeding trial.
Design
Longitudinal study.
Setting
Information about vitamin D supplementation was collected through a validated FFQ at the age of 2 weeks and monthly between the ages of 1 month and 6 months.
Subjects
Infants (n 2159) with a biological family member affected by type 1 diabetes and with increased human leucocyte antigen-conferred susceptibility to type 1 diabetes from twelve European countries, the USA, Canada and Australia.
Results
Daily use of vitamin D supplements was common during the first 6 months of life in Northern and Central Europe (>80 % of the infants), with somewhat lower rates observed in Southern Europe (>60 %). In Canada, vitamin D supplementation was more common among exclusively breast-fed than other infants (e.g. 71 % v. 44 % at 6 months of age). Less than 2 % of infants in the USA and Australia received any vitamin D supplementation. Higher gestational age, older maternal age and longer maternal education were study-wide associated with greater use of vitamin D supplements.
Conclusions
Most of the infants received vitamin D supplements during the first 6 months of life in the European countries, whereas in Canada only half and in the USA and Australia very few were given supplementation.
Parkinson's disease (PD) is associated with significant symptoms of depression. Cognitive behaviour therapy (CBT) has been shown to be effective for depression in PD. However, much of the previous research focuses on working with younger adults in the earlier stages of the disease, despite evidence for greater risk of depression when PD symptoms are more severe. This paper provides a case illustration of using CBT for depression with an 84-year-old man with advanced PD. The results of an assessment are described and a psychological formulation is presented. The specific adaptations made to the therapy and illustrations of the content of therapy are discussed. This intervention resulted in improvements in global mental health and moderate reductions in depression. However, there was no effect on anxiety. This case highlights the complexity of conducting CBT with this population, and further research is needed to determine the modifications necessary to make such interventions effective.
Excavations at Tinney's Lane, Sherborne in 2002 uncovered extensive evidence for Late Bronze Age settlement and pottery production, dating from a short time period probably within the 12th or 11th century cal bc. Well-preserved deposits of burnt stone, broken vessels, and burnt sherds, together with resulting debris redeposited in associated pits, were accompanied by a series of post-hole structures interpreted as round-houses and four-post settings. Environmental evidence in the form of charcoal, charred plant remains, and molluscs has provided important information concerning sources of fuel and water for pottery production as well as allowing a reconstruction of the local vegetation. Finds of fired clay, metal, stone, shale, flint, and bone include items from distant sources, informing topics such as site status and exchange, and include many categories of tools and equipment that would have been used within the pottery-making processes. Analysis of the spatial distribution of these finds amongst the structures and surviving layers of burning has allowed the definition of a series of industrial activity areas, each comprising one or more round-houses, a four-post structure, bonfire bases or pits used for firing, and other pits with specific related functions. Altogether the site has provided some of the best evidence for pottery production within prehistoric Britain.
Data from the Survey on Ageing and Independence are employed to test the relationship between stress, integration in close family and friend networks, and well-being with a particular emphasis on parent status. The dependent variables used in this analysis are, whether individuals have a close family member or a close friend, the number of reported close relatives and friends, life stress, and the affect balance scale. It is hypothesized that the zero order relationship often found between parent status and well-being may be due to (1) a fundamental difference in the social support experiences of older parents and older childless individuals, (2) different levels of stress among these groups, or (3) the potential of friends to be of greater importance in assuring well-being in older age than family. Results show that childless persons are less likely than parents to have at least one close family member and they have fewer close relatives. No parent status differences are found regarding the likelihood of having a close friend or in the number of close friends individuals have. Compared to parents, childless individuals experience less life stress and similar levels of well-being. Finally, the nature of the stress-support-well-being relationship appears to be the same regardless of parent status.
The risk of the Nene Branta sandvicensis becoming extinct has been minimized by the release of over 2,000 captive-reared geese, but the population (now at 500) is yet to achieve a self-sustaining status. The majority of birds released have been reared in gosling-only groups, thus missing out on the opportunity to learn social and feeding skills from adults. In this paper we test the hypothesis that rearing experience affects the subsequent behavioural traits of Nene goslings. We raised 42 goslings under four conditions: a gosling group not exposed to adults, a gosling group exposed to adults from 16 days onward, three groups in view of “foster” adults for 14 days, and four groups reared continuously by parents. All birds were eventually released into an 8 ha pen where a flock of adult Nene roamed. The method by which Nene goslings were raised had a significant effect on dominance, flock integration, and vigilance. Parent-reared birds were dominant to and more vigilant than goslings raised without parents or goslings reared in sight of adults. Parent-reared birds also integrated into the adult flock sooner than other goslings. Growth rate and final body size were not affected by rearing regime (with or without parents or foster parents). In future, managers should provide goslings with as much “parental” experience as possible in order to equip them with appropriate skills to cope once released in the wild.