Evidence for fire affecting the solubility of metals in Fe oxide-rich Oxisols of the Koniambo Massif of New Caledonia is presented. Acid-dissolution studies showed that Ni, Al and Cr are substituted for Fe in the structure of the Fe oxides. Thermal dehydroxylation of goethite under oxidizing conditions led to the formation of hematite and to the migration of some of these metals towards the surface of hematite crystals as indicated by their enhanced release during the early stage of dissolution. Dehydroxylation of goethite under reducing conditions led to the formation of hematite and maghemite. Nickel and Al were released preferentially during the early stages of dissolution whereas Cr was not released preferentially and may be uniformly incorporated within maghemite and hematite crystals. These results have significance to the mineral-processing industry, to geochemical exploration and to the availability of these metals to plants growing on burnt soils.

It is unclear if mild-to-moderate dehydration independently affects mood without confounders like heat exposure or exercise. This study examined the acute effect of cellular dehydration on mood. Forty-nine adults (55 % female, age 39 (sd 8) years) were assigned to counterbalanced, crossover trials. Intracellular dehydration was induced with 2-h (0·1 ml/kg per min) 3 % hypertonic saline (HYPER) infusion or 0·9 % isotonic saline (ISO) as a control. Plasma osmolality increased in HYPER (pre 285 (sd 3), post 305 (sd 4) mmol/kg; P < 0·05) but remained unchanged in ISO (pre 285 (sd 3), post 288 (sd 3) mmol/kg; P > 0·05). Mood was assessed with the short version of the Profile of Mood States Questionnaire (POMS). The POMS sub-scale (confusion-bewilderment, depression-dejection, fatigue-inertia) increased in HYPER compared with ISO (P < 0·05). Total mood disturbance score (TMD) assessed by POMS increased from 10·3 (sd 0·9) to 16·6 (sd 1·7) in HYPER (P < 0·01), but not in ISO (P > 0·05). When TMD was stratified by sex, the increase in the HYPER trial was significant in females (P < 0·01) but not in males (P > 0·05). Following infusion, thirst and copeptin (surrogate for vasopressin) were also higher in females than in males (21·3 (sd 2·0), 14·1 (sd 1·4) pmol/l; P < 0·01) during HYPER. In conclusion, cellular dehydration acutely degraded specific aspects of mood mainly in women. The mechanisms underlying sex differences may be related to elevated thirst and vasopressin.

To study the reliability of two depression assessment scales, the Montgomery-Asberg Depression Rating Scale and the Psychomotor Retardation Scale, 30 patients with depression according to Feighner's criteria were evaluated, by two groups of raters: 5 were trained psychiatrists or psychologists, and 6 were untrained raters. The experiment lasted three months. The patients were recorded on video-tape by two psychiatrists who did not take part in the experiment, during pre-designed interviews. Each scoring was discussed by the trained group but not by the untrained group. The Kappa test and the sign-test were used for the statistical analysis of global and itemized results, respectively. Intraclass coefficient Q3 was applied to global scores. With regard to global scores, there was no significant difference among the members of the trained group, who scored higher than those of the untrained group; a significant difference between some of the untrained raters, induced a significant difference with the trained group. With regard to each item of both scales, reliability appeared to be slight to moderate, and there was no significant difference between trained and inexpert raters. These results are discussed and modifications are proposed to improve the consistency of the two scales. The authors emphasize the necessity for therapeutic trials to be conducted with permanent groups of assessors who continue training even outside of trial procedures.

Measurements of the thermal creep flow through a single rectangular microchannel connected to two tanks maintained initially at the same pressure, but at different temperatures, are carried out for five noble gas species, over a large range of pressure and for two temperature differences between the tanks. The time-dependent pressure variations in both cold and hot tanks are investigated, and the temperature-driven (thermal creep) mass flow rate between two tanks is calculated from these data for the rarefaction parameter ranging from the transitional to slip flow regime. The measured mass flow rate is compared with the numerical solution of the S-model kinetic equation, and they show good agreement. A novel approximate expression to calculate the temperature-driven mass flow rate in the transitional and slip flow regimes is proposed. This expression provides results in good agreement with the measured values of the mass flow rate. In the slip flow regime, the thermal slip coefficient is calculated by employing the previously reported methodology, and the influence of the nature of the gas on this coefficient is investigated. The measured values of the thermal slip coefficient agree well with the values available in the literature, indicating that this coefficient is independent of the shape of a channel.

Systematic collecting through the upper Wenlock (upper Homerian) and lower Ludlow (Gorstian and lowermost Ludfordian) Silurian rock succession of the Long Mountain, Powys, Wales, identifies some 48 chitinozoan species that distinguish four biozones, two subzones and an interregnum. Consideration of the chitinozoan biozones together with those of the graptolites enables a local three-fold subdivision of the late Homerian lundgreni graptolite Biozone, and the distinction of lower and upper intervals for the Gorstian incipiens graptolite Biozone. The base of the Ludlow Series in the Long Mountain more or less equates to the base of the Cingulochitina acme chitinozoan Biozone, although no key chitinozoan first or last appearance datums are associated with the series boundary itself. The new graptolite–chitinozoan biozonation allows enhanced correlation between upper Wenlock and lower Ludlow sedimentary deposits of the Lower Palaeozoic Welsh depositional basin and those of the palaeo-shelf in the stratotype Wenlock and Ludlow areas of Shropshire. Chitinozoans seem affected by the phenomena that caused the late Wenlock ‘Mulde extinction’ in graptolites but, with the final disappearance of 9 species and re-appearance of 11 species following an interval of overall low diversity, they seem to have suffered less severely than their macro-zooplanktonic contemporaries.

Bradoriids are small bivalved arthropods that had global distribution for about 20 million years beginning at Cambrian Epoch 2 (c. 521 Ma). The majority of bradoriids are considered to be benthic, favouring oxygenated waters, as suggested by their anatomy, lithofacies distribution, faunal associates and provinciality. Most bradoriids were extinct by the end of the Drumian Age (middle of Cambrian Epoch 3). The post-Drumian is characterized by widespread dysoxic shelf lithofacies in southern Britain and Scandinavia and by the abundance of phosphatocopid arthropods. This interval is also associated with two bradoriid species with wide intercontinental distribution: Anabarochilina primordialis, which had a geographical range from the palaeo-tropics to high southern palaeo-latitude, and Anabarochilina australis, which extended through the palaeo-tropics from Laurentia to Gondwana. The wide environmental and geographical range of these species, coupled with a carapace anatomy that suggests an active lifestyle, is used to infer a zooplanktonic lifestyle. A possible driver of this widespread Cambrian bradoriid zooplankton was sea-level rise coupled to the periodic spread of low oxygen conditions onto continental shelves, acting in tandem with anatomical pre-adaptations for swimming. Parallels exist with the myodocope ostracod colonization of the water column during Silurian time, which may also have been influenced by extrinsic environmental controls acting on anatomical pre-adaptations for swimming. Similar biological and environmental mechanisms may have facilitated arthropod zooplankton colonizations across Phanerozoic time.

Although Malta is historically linked with the zoonosis brucellosis, there had not been a case of the disease in either the human or livestock population for several years. However, in July 2013 a case of human brucellosis was identified on the island. To determine whether this recent case originated in Malta, four isolates from this case were subjected to molecular analysis. Molecular profiles generated using multilocus sequence analysis and multilocus variable number tandem repeat for the recent human case isolates and 11 Brucella melitensis strains of known Maltese origin were compared with others held on in-house and global databases. While the 11 isolates of Maltese origin formed a distinct cluster, the recent human isolation was not associated with these strains but instead clustered with isolates originating from the Horn of Africa. These data was congruent with epidemiological trace-back showed that the individual had travelled to Malta from Eritrea. This work highlights the potential of using molecular typing data to aid in epidemiological trace-back of Brucella isolations and assist in monitoring of the effectiveness of brucellosis control schemes.

Here we record the occurrence of a new species of the Herefordshire Lagerstätte ostracod genus Pauline from the Lower Silurian (upper Telychian) of North Greenland. Pauline nivisis sp. nov. was recovered from a limestone boulder (Pentamerus Bjerge Formation) collected south of Kap Schuchert, Washington Land. It is reasonable to transpose the palaeobiology known from the Herefordshire Pauline avibella – body, limbs including swimming antennae, lateral eyes, gills and alimentary system – into the carapace of the Greenland species, which represents the oldest cylindroleberidid myodocopid and almost the oldest known myodocope, and is the first record of a Herefordshire Lagerstätte genus from outside the Welsh Borderland locality. Morphological, sedimentological and faunal evidence suggest that the Greenland species was nektobenthic. This is compatible with the notion that ostracods (specifically myodocopids) did not invade the water column until later in the Silurian, in the Wenlock and Ludlow epochs. Pauline is an Early Silurian link between ‘Baltic-British’ and North Laurentian ostracod faunas, endorsing the idea that the UK and Greenland were in close geographical proximity, near a remnant Iapetus Ocean, during late Llandovery time.

A fully instrumented microscale shock tube, believed to be the smallest to date, has been fabricated and tested. This facility is used to study the transmission of a shock wave, produced in a large (37 mm) shock tube, into a 34  $\mathrm{\mu} \mathrm{m} $ hydraulic diameter and 2 mm long microchannel. Pressure microsensors of a novel design, with gigahertz bandwidth, are used to obtain pressure–time histories of the microchannel shock wave at five axial stations. In all cases the transmitted shock wave is found to be weaker than the incident shock wave, and is observed to decay both in pressure and velocity as it propagates down the microchannel. These results are compared with various analytical and numerical models, and the best agreement is obtained with a Navier–Stokes computational fluid dynamics computation, which assumes a no-slip isothermal wall boundary condition; good agreement is also obtained with a simple shock tube laminar boundary layer model. It is also found that the flow developing within the microchannel is highly dependent on conditions at the microchannel entrance, which control the mass flux entering into the device. Regardless of the micrometre dimensions of the present facility, shock wave propagation in a microchannel of that scale exhibits a behaviour similar to that observed in large-scale facilities operated at low pressures, and the shock attenuation can be explained in terms of accepted laminar boundary models.

In 2011 the IRSN conducted several assessments of atmosphericradioactive releases due to the Fukushima Daiichi NPP accident (March11, 2011) and of their impact on Japan’s terrestrial environment.They were based on the IRSN’s emergency management tools and onthe abundant information and technical data gradually publishedin Japan. According to these assessments, the main release phaselasted from March 12 to 25, 2011 and impacted Japanese land in twoevents, the first on 15 and 16 March, in which the main radioactivedeposits were formed, and the second from March 20 to 23, whichwas less significant. The highest amounts of radioactive deposits werefound in an area extending upwards of several tens of kilometersnorthwest of the plant. Lower amounts were discontinuously scatteredin an area extending up to over 250 km away. Initially composedmainly of short-lived radionuclides, the deposits’ activity sharplydecreased in the subsequent weeks. Since the summer of 2011, cesium-134and cesium-137 have become the residual deposits’ main components.According to IRSN estimates, in the absence of protection, the dosesdue to exposure to the radioactive plume during the atmosphericrelease phase may have been potentially higher for people who remainedin coastal areas up to several tens of kilometers north and southof the damaged plant. Thereafter, people living up to 50 km northwestof the plant, outside the 20-km emergency evacuation zone, were potentiallymost vulnerable to residual radioactive deposits over time.

Cognitive and affective complaints are common in patients with primary hyperparathyroidism (PHPT), but few studies have used psychometric testing to document these symptoms and their response to parathyroidectomy. The current study sought to clarify the nature of cognitive and affective impairments in PHPT and changes postparathyroidectomy. One hundred eleven patients with PHPT underwent neuropsychological evaluation prior to parathyroidectomy with 68 returning for an early postsurgical evaluation. Changes in cognition were assessed using practice effect corrected reliable change indices. Biochemical and anesthesia variables were compared between groups who improved and declined. In a subset of patients, assessment revealed a significant pattern of cognitive slowing, reductions in psychomotor speed, memory impairment, and depression prior to parathyroidectomy. Postsurgical evaluations revealed a trend for improvements on timed tests and depression but a decline in memory. Older patients responded less well to surgical intervention, as did patients who experienced more dramatic changes in biochemical status following surgery. Cognitive changes early postparathyroidectomy are characterized by improved information processing speed and decline in verbal memory, with younger patients more likely to recover during this acute phase. The need for longer-term follow-up studies and increasing utilization of neuropsychological assessments in this population are discussed. (JINS, 2009, 15, 1002–1011.)

Protecting the environment and the public from radioactive hazard is a top priority for all companies operating in the nuclear domain. In order to quantify dose impact on members of the public due to annual discharges of its nuclear installations, AREVA developed the COMODORE code in collaboration with Institute of Radiation Protection and Nuclear Safety (IRSN).

COMODORE is a synthesis of 3 softwares validated by IRSN (ACADIE, COTRAM and AQUAREJ). ACADIE is a code elaborated by IRSN and the Treatment Business Unit of AREVA synthesizing the works of the GRNC (Nord-Cotentin Radioecology Group) created by the French government to deal with the estimation of exposure levels to ionizing radiation and associated risks of leukemia for populations in the Nord-Cotentin. COMODORE is a version of ACADIE designed to be adaptable to any other AREVA site. Thus, the operators of the south east of France (Pierrelatte, Marcoule and Romans sites) carried out the adaptation of COMODORE for theirs specificities (for instance, uranium in the terrestrial model).

At the moment, COMODORE is used in routine by the AREVA operators to assess the annual dosimetric impact and is also being adapted with SGN to model the radiological impact of uranium ore treatment residues repositories.

A study of type and newly collected material of the Silurian ostracod Richteria migrans (Barrande, 1872) demonstrates that it had wide distribution, occurring in at least the Czech Republic, France, Sardinia, Wales, central Asia and probably Poland. R. migrans has biostratigraphic value, as an indicator for the mid to late part of the Ludlow Series. It was almost certainly pelagic, living predominantly in probable shelf topographic lows to marginal/off-shelf environments, characteristically with cephalopod-graptolite-bivalve-dominant associates. It had at least five to six growth stages, exhibits polymorphic variation, and its morphology provides evidence to endorse the notion that ‘entomozoaceans’ are myodocopes.

Helium mass flow rates in a microchannel were measured, for a wide Knudsen-number range, in isothermal steady conditions. The flow Knudsen numbers, considered here, cover the range from continuum slip regime to the near free molecular regime. We used a single-channel system involved in an experimental platform more powerful than those previously used. The experimental errors and uncertainties were accurately investigated and estimated. In the continuum slip regime, it was found that the first-order approach is pertinent for Knudsen number between 0.03 and 0.3. Moreover, the slip coefficient was deduced by comparing the experiments with the theoretical first-order slip continuum approach. For Knudsen number between 0.03 and 0.7, a polynomial second-power form is proposed for the mass flow rate expression. Otherwise, the experimental results on the mass flow rate were compared with theoretical values calculated from kinetic approaches over the 0.03–50 Knudsen number range, and an overall agreement appears through the comparison. It was also found, when the Knudsen number increased, that the wall influence on measurement occurred first through the accommodation process in the transition regime followed by the wall influence through the aspect ratio in the free molecular regime.

L’objectif de cette étude est de faire le point sur l’irradiation du patient dans le domaine de la radiologie dentaire. Les avancées technologiques en imagerie médicale amènent des perspectives intéressantes quant aux possibilités de réduction des doses. Dans ce travail, les doses délivrées aux patients lors d’examens intra-oraux, panoramiques et tomographiques, ont été évaluées sur quelques installations. La dose au patient est généralement estimée en utilisant des indicateurs dosimétriques, tels que le kerma dans l’air à la surface d’entrée du patient (KASE) et le produit kerma surface (PKS). Ces valeurs sont facilement mesurables et permettent d'évaluer la dose efficace pour un patient standard. Le PKS a été mesuré pour un système intra-oral analogique muni de films de sensibilité D et E/F, ainsi que pour une installation munie d’un détecteur numérique. Afin d’évaluer les doses en radiographie panoramique, le PKS a également été déterminé pour des orthopantomogrammes (OPGs) de différentes générations. Finalement, les doses délivrées aux patients lors d’examens tomographiques en implantologie ont été évaluées à l’aide des mesures du produit kerma longueur (PKL) et de l'indice dedose en tomodensitométrie (CTDIw) pour deux types d’installation : un tomodensitomètre muni des fonctions Dentascan et un système dédié basé sur la technique DVT (Digital Volume Tomography). L'utilisation d’un film E/F au lieu d’un film D permet de réduire le PKS d’un facteur 2 avec une légère augmentation du bruit de l’image. Les systèmes numériques permettent une réduction additionnelle de la dose d’un facteur 6 mais avec une dégradation importante de la résolution spatiale (passage de la FTM à 50 % de 13 mm–1 à 5 mm–1). Le PKS mesuré sur les OPGs a démontré que l’ancien système génère une dose trois fois plus élevée qu'un système plus récent. Le système de tomographie dédié permet de réduire la dose au patient d’un facteur 18 en comparaison avec un système CT Dentascan.

We present radial-velocity measurements for three solar-type stars (HD 127506, HD 174457 and HD 185414) hosting low-mass companions. The measurements were obtained with the ELODIE echelle spectrograph mounted on the 1.93–m telescope at Observatoire de Haute–Provence (CNRS, France) within the frame of the OHP-ELODIE Planet Search Programme. The inferred minimum masses of the detected companions are in the substellar mass range. Combining ELODIE radial-velocity data and HIPPARCOS astrometric data, the inclination angles of the orbital planes of HD 127506 and HD 174457 have been derived providing us with the de-projected masses of the companions: m 2 = 44MJup for the companion of HD 127506 and m 2= 0.13M⊙ for the companion of HD 174457. Moreover, using adaptive optics measurements, we show that HD 174457 is probably a (F8V + M7V + M3-4V) triple system. To date, only a minimal orbital solution is available for HD 185414.