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Social impact has been widely discussed by the engineering community, but studies show that there is currently little systematic consideration of the social impact of products in both academia and in industry beyond social impacts on health and safety. While Failure Mode and Effect Analysis (FMEA) is useful for evaluating health and safety risks, new developments are needed to create an FMEA-style evaluation that can be applied to a wide range of social impacts for engineered products. The authors describe necessary modifications to traditional FMEA that transform it into a tool for social impact analysis. The modification of FMEA involves the introduction of positive and negative impacts, the inclusion of discrete and continuous impacts, the consideration of various stakeholder types, and the inclusion of uncertainty in place of detectability. This modified FMEA is referred to in this paper as Social Impact Effects Analysis (SIEA). The paper describes how SIEA is performed and articulates the potential benefits of SIEA.
The Southern Uplands-Down-Longford Terrane (SUDLT) saw exploration for coal in Ordovician-Silurian marine rocks for several centuries, including well after it was understood that land plant coals would not occur in such rocks. Some lithologies were so carbonaceous that a fuel of sorts was mined. The record of this exploration and mining activity is mostly forgotten, but there are diverse sources to show that it was widespread. Exploration was mostly inspired by outcrops of Moffat Shale, in which deformation and hydrocarbon generation left coal-like products. The hydrocarbon origin conferred high calorific value to the fuel, so it did burn and encouraged exploration. The deposits show that an accretionary prism can be a reservoir of locally abundant carbon.
Long-term monitoring of reintroduced populations may: inform ongoing management decisions for the focal population, such as supplementary feeding or harvesting; make it possible to predict the future viability of small populations, and therefore the need for genetic management; inform site selection for further reintroductions, for example by showing how survival and reproduction rates vary with climatic conditions; facilitate our ability to ability to predict population dynamics at new reintroduction sites, for example by informing values for parameters that can be estimated only from long-term data; and improve our understanding of the dynamics of reintroduced populations, so future monitoring and management can focus on the key factors affecting persistence.
We present a recurrence–transience classification for discrete-time Markov chains on manifolds with negative curvature. Our classification depends only on geometric quantities associated to the increments of the chain, defined via the Riemannian exponential map. We deduce that a recurrent chain that has zero average drift at every point cannot be uniformly elliptic, unlike in the Euclidean case. We also give natural examples of zero-drift recurrent chains on negatively curved manifolds, including on a stochastically incomplete manifold.
The severe acute respiratory coronavirus virus 2 (SARS-CoV-2) delta variant is highly transmissible, and current vaccines may have reduced effectiveness in preventing symptomatic infection. Using epidemiological and genomic analyses, we investigated an outbreak of the variant in an acute-care setting among partially and fully vaccinated individuals. Effective outbreak control was achieved using standard measures.
The impact of engineered products is a topic of concern in society. Product impact may fall under the categories of economic, environmental or social impact, with the last category defined as the effect of a product on the day-to-day life of people. Design teams lack sufficient tools to estimate the social impact of products, and the combined impacts of economic, environmental and social impacts for the products they are designing. This paper aims to provide a framework for the estimation of product impact during product design. To estimate product impact, models of both the product and society are required. This framework integrates models of the product, scenario, society and impact into an agent-based model to estimate product impact. Although this paper demonstrates the framework using only social impact, the framework can also be applied to economic or environmental impacts individually or all three concurrently. Agent-based modelling has been used previously for product adoption models, but it has not been extended to estimate product impact. Having tools for impact estimation allows for optimising the product design parameters to increase the potential positive impact and reduce potential negative impact.
The impact of products is becoming a topic of concern in society. Product impact may fall under the categories of economic, environmental, or social impact and is defined by the effect of a product on day-to-day life. Design teams lack sufficient tools to predict the impact of products they are designing. In this paper we present a framework for the prediction of product impact during product design. This framework integrates models of the product, scenario, society, and impact into an agent-based model to predict product impact. Although this paper focuses on social impact, the framework can also be applied to economic or environmental impacts. An illustration of using the framework is also presented. Agent-based modeling has been used previously for adoption models, but it has not been extended to predict product impact. Having tools for impact prediction allows for optimizing the product design parameters to increase potential positive impact and reduce potential negative impact.
Previously, it was suggested that haemadipsid leeches represent an important vector of trypanosomes amongst native animals in Australia. Consequently, Chtonobdella bilineata leeches were investigated for the presence of trypanosome species by polymerase chain reaction (PCR), DNA sequencing and in vitro isolation. Phylogenetic analysis ensued to further define the populations present. PCR targeting the 28S rDNA demonstrated that over 95% of C. bilineata contained trypanosomes; diversity profiling by deep amplicon sequencing of 18S rDNA indicated the presence of four different clusters related to the Trypanosoma (Megatrypanum) theileri. Novy–MacNeal–Nicolle slopes with liquid overlay were used to isolate trypanosomes into culture that proved similar in morphology to Trypanosoma cyclops in that they contained a large numbers of acidocalcisomes. Phylogeny of 18S rDNA/GAPDH/ND5 DNA sequences from primary cultures and subclones showed the trypanosomes were monophyletic, with T. cyclops as a sister group. Blood-meal analysis of leeches showed that leeches primarily contained blood from swamp wallaby (Wallabia bicolour), human (Homo sapiens) or horse (Equus sp.). The leech C. bilineata is a host for at least five lineages of Trypanosoma sp. and these are monophyletic with T. cyclops; we propose Trypanosoma cyclops australiensis as a subspecies of T. cyclops based on genetic similarity and biogeography considerations.
The coronavirus disease 2019 (COVID-19) created major disruptions at academic centers and healthcare systems globally. Clinical and Translational Science Awards (CTSA) fund hubs supported by the National Center for Advancing Translational Sciences provideinfrastructure and leadership for clinical and translational research at manysuch institutions.
Methods:
We surveyed CTSA hubs and received responses from 94% of them regarding the impact of the pandemic and the processes employed for the protection of research personnel and participants with respect to the conduct of research, specifically for studies unrelated to COVID-19.
Results:
In this report, we describe the results of the survey findings in the context of the current understanding of disease transmission and mitigation techniques.
Conclusions:
We reflect on common practices and provide recommendations regarding lessons learned that will be relevant to future pandemics, particularly with regards to staging the cessation and resumption of research activities with an aim to keep the workforce, research participants, and our communities safe in future pandemics.
This work compares dose-volume constraints (DVCs) and tumour control predictions based on the average intensity projection (AVIP) to those on each phase of the four-dimensional computed tomography.
Materials and methods:
In this prospective study plans generated on an AVIP for nine patients with locally advanced non-small-cell lung cancer were recalculated on each phase. Dose-volume histogram (DVH) metrics extracted and tumour control probabilities (TCP) were calculated. These were evaluated by Bland–Altman analysis and Pearson Correlation.
Results:
The largest difference between clinical target volume (CTV) on the individual phases and the internal CTV (iCTV) on the AVIP was seen for the smallest volume. For the planning target volume, the mean of each metric across all phases is well represented by the AVIP value. For most patients, TCPs from individual phases are representative of that on the AVIP. Organ at risk metrics from the AVIP are similar to those seen across all phases.
Findings:
Utilising traditional DVH metrics on an AVIP is generally valid, however, additional investigation may be required for small target volumes in combination with large motion as the differences between the values on the AVIP and any given phase may be significant.
This book collects seventeen previously published essays by John Armstrong concerning the British coastal trade. Armstrong is a leading maritime historian and the essays provided here offer a thorough exploration of the British coastal trade, his specialisation, during the period of industrialisation and technological development that would lead to modern shipping. The purpose is to demonstrate the whether or not the coastal trade was the main carrier of internal trade and a pioneer of the technical developments that modernised the shipping industry. Each essay makes an original contribution to the field and covers a broad range of topics, including the fluctuating importance of the coastal trade and size of the coastal fleet over time; the relationship between coastal shipping, canals, and railways; a comparison between the coastal liner and coastal tramp trade; the significance of the river Thames in enabling trade; coastal trade economics; maritime freight rates; the early twentieth century shipping depression; competition between coastal liner companies; and a detailed study of the role of the government in coastal shipping. The book also contains case studies of the London coal trade; coastal trade through the River Dee port; and the Liverpool-Hull trade route. It contains a foreword, introduction, and bibliography of Armstrong's writings. There is no overall conclusion, except the assertion that coastal shipping plays a tremendous role in British maritime history, and a call for further research into the field.
This paper addresses longstanding questions about how promise and obligation, two of the key conceptual building blocks for psychological contract research, are conceptualized and operationalized: How do employees understand these concepts? Would their understandings be congruent with the researchers’ and how would this knowledge inform future psychological contract research? Drawing on interviews with 61 Chinese workers from diverse backgrounds, our results suggest the concepts have distinct meanings for participants in terms of three criteria (defining characteristics, key features and manifestations in employment). We argue that promise and obligation are likely to serve different functions in employment relationship and have different meanings for researchers versus participants, and accordingly we highlight the challenges of using them to conceptualize and operationalize psychological contracts in China and beyond.
For fifty years the Soviet Bloc constituted one pole of an essentially bipolar world power distribution. Although not unprecedented (consider Imperial Germany's defiance of most of the world during 1917–18, or later phases of Napoleon's challenge to Europe), bipolarism has usually been very brief. The sheer length of time the Soviet-American confrontation dominated world politics created, on the contrary, mind-sets and reflexes which only a conscious effort can overcome.
This book presents an in-depth study of the impact of the steamship on Britain during its first forty years, roughly between 1810 and 1850. It relates the early steamship to several industrial themes including diffusion; construction; modernisation; the role of government - particularly the difficult attempt to align laissez-faire politics with the greater need for public safety measures due to technological advance; business and finance; plus public reaction and tourism. The aim is to establish the significance of the steamship as a conduit of modernisation and societal change. It consists of a foreword, introduction, and fourteen chapters devoted to specific themes, structured to ensure each chapters build on the preceding chapter's progress. Collectively, they demonstrate that the development of both experience and enterprise with steam power both gained and refined during this period made the mid-century expansion of steamship technology across Britain possible. Ultimately, it establishes that steamship services began to adapt to oceanic routes, steam began to integrate into the world economy, and the age of sail began to draw to a close.