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The optimal timing of functional endoscopic sinus surgery for odontogenic infections precipitated by retention cysts of the maxillary sinus was investigated.
Methods
Five adults who underwent functional endoscopic sinus surgery were examined.
Results
The root apexes of all teeth that had odontogenic infection protruded into the maxillary sinus. All teeth with odontogenic infections precipitated by the retention cysts had percussion pain, indicating they had periodontitis and pulpitis around the root apex. They were vital teeth, indicating they did not have pulp necrosis. The small area of cyst wall attached to the floor of the maxillary sinus and root apex were left intact. The teeth that had odontogenic infections precipitated by retention cysts continued to be vital with no symptoms.
Conclusion
Functional endoscopic sinus surgery should be performed before periodontitis and pulpitis of the root apex progress to ascending pulpitis and pulp necrosis. In other words, functional endoscopic sinus surgery should be performed while the affected tooth is still vital.
Cells in the vocal fold of maculae flavae are likely to be tissue stem cells. Energy metabolism of the cells in newborn maculae flavae was investigated from the aspect of mitochondrial microstructure.
Method
Five normal newborn vocal folds were investigated under transmission electron microscopy.
Results
Mitochondria consisted of a double membrane bounded body containing matrices and a system of cristae. However, these membranes were ambiguous. In each mitochondrion, the lamellar cristae were sparse. Intercristal space was occupied by a mitochondrial matrix. Some mitochondria had fused to lipid droplets and rough endoplasmic reticulum, and both the mitochondrial outer and inner membranes had incarcerated and disappeared.
Conclusion
The features of the mitochondria of the cells in the newborn maculae flavae showed that their metabolic activity and oxidative phosphorylation were low. The metabolism of the cells in the newborn maculae flavae seems to be favourable to maintain the stemness and undifferentiation of the cells.
We report fourteen and twenty-eight protocluster candidates at z = 5.7 and 6.6 over 14 and 19 deg2 areas, respectively, selected from 2,230 Lyα emitters (LAEs) photometrically identified with Subaru/Hyper Suprime-Cam (HSC) deep images. Six out of the 42 protocluster candidates include at least 1 spectroscopically confirmed LAEs at redshifts up to z = 6.574. By the comparisons with the cosmological Lyα radiative transfer (RT) model reproducing LAEs with the reionization effects, we find that more than a half of these protocluster candidates might be progenitors of the present-day clusters with a mass of ≳ 1014M⊙. We also investigate the correlation between LAE overdensity and Lya rest-frame equivalent width (EW), because the cosmological Lyα RT model suggests that a slope of EW-overdensity relation is steepened towards the epoch of cosmic reionization (EoR), due to the existence of the ionized bubbles around galaxy overdensities easing the escape of Lyα emission from the partly neutral intergalactic medium. The available HSC data suggest that the slope of the EW-overdensity correlation does not evolve from the post-reionization epoch z = 5.7 to the EoR z = 6.6 beyond the moderately large statistical errors.
Perovskite-based solar cells, typically CH3NH3PbI3, have reached power conversion efficiencies on par with single crystal silicon solar cells. Perovskite cells prepared with the most common perovskite solvent N,N-dimethylformamide (DMF) by different research groups exhibit disparate efficiencies and stability for nominally identical perovskite films. Although the differences can be related to processing conditions, a consistent physical cause for the differences has been lacking. Highly-sensitive time-of-flight secondary ion mass spectrometry (TOF-SIMS) reveals significant dimethylamine (DMA) included in perovskite films. TOF-SIMS and x-ray photoelectron spectroscopy results suggest DMA levels ranging from roughly 10–50%. Only the highest levels register as perovskite peak shifts in x-ray diffraction; lower levels are invisible. We propose that methylamine (MA) can react with DMF solvent by transamidation to produce dimethylamine (DMA), which then displaces some MA in perovskite crystals, see Fig. 1. Transamidation of DMF can be catalyzed by TiO2, Al2O3, water, or acid, but in perovskite films transamidation is inhibited by water.
The Keio Twin Research Center has conducted two longitudinal twin cohort projects and has collected three independent and anonymous twin data sets for studies of phenotypes related to psychological, socio-economic, and mental health factors. The Keio Twin Study has examined adolescent and adult cohorts, with a total of over 2,400 pairs of twins and their parents. DNA samples are available for approximately 600 of these twin pairs. The Tokyo Twin Cohort Project has followed a total of 1,600 twin pairs from infancy to early childhood. The large-scale cross-sectional twin study (CROSS) has collected data from over 4,000 twin pairs, from 3 to 26 years of age, and from two high school twin cohorts containing a total of 1,000 pairs of twins. These data sets of anonymous twin studies have mainly targeted academic performance, attitude, and social environment. The present article introduces the research designs and major findings of our center, such as genetic structures of cognitive abilities, personality traits, and academic performances, developmental effects of genes and environment on attitude, socio-cognitive ability and parenting, genes x environment interaction on attitude and conduct problem, and statistical methodological challenges and so on. We discuss the challenges in conducting twin research in Japan.
The material properties of two ultra low-k organic polymers are characterized for copper interconnect integration. The k-values are 2.2-2.3 for both. Compared to OSG materials of similar k-values, these polymers have lower porosity and smaller pore size, achieved using selfassembled chemistry. Both materials demonstrate excellent resistance to plasma damage: no water uptake was detected after exposure to selected etching plasmas. This characteristic, combined with the small pore size and low porosity, results in the successful integration of the organic low-ks in 80 nm spacing with no significant increase in the integrated k-values.
It is found that higher open porosity in polymer A is accompanied by higher leakage current, which is not however linked to lower dielectric breakdown lifetimes.
This study aimed to clarify the significance of cluster of differentiation 9 glycoprotein gene expression in human parotid gland tumours.
Methods:
We retrospectively analysed immunohistochemical staining for cluster of differentiation 9 glycoprotein in parotid gland tumours.
Results:
Cluster of differentiation 9 glycoprotein was consistently detected in the normal parotid gland. Regarding benign parotid gland tumours, cluster of differentiation 9 glycoprotein was present in 13 of 18 pleomorphic adenomas, in all Warthin tumours tested (21/21) and in all cases of basal cell adenoma tested (four of four). In contrast, positive staining for cluster of differentiation 9 glycoprotein was less often observed in malignant parotid tumours. Cluster of differentiation 9 glycoprotein was present in 11 of 14 mucoepidermoid carcinomas, in two of five acinic cell carcinomas and in two of five adenoid cystic carcinomas.
Conclusions:
There was a statistically significantly reduced expression of cluster of differentiation 9 glycoprotein in malignant parotid gland tumours, compared with benign parotid gland tumours (p < 0.05). These results suggest that a low level of cluster of differentiation 9 glycoprotein expression in parotid gland tumours may be associated with malignancy.
Suicide is a leading cause of death worldwide; however, the prevalence and risk factors for the immediate precursors to suicide – suicidal ideation, plans and attempts – are not well-known, especially in low- and middle-income countries.
Aims
To report on the prevalence and risk factors for suicidal behaviours across 17 countries.
Method
A total of 84 850 adults were interviewed regarding suicidal behaviours and socio-demographic and psychiatric risk factors.
Results
The cross-national lifetime prevalence of suicidal ideation, plans, and attempts is 9.2% (s.e.=0.1), 3.1% (s.e.=0.1), and 2.7% (s.e.=0.1). Across all countries, 60% of transitions from ideation to plan and attempt occur within the first year after ideation onset. Consistent cross-national risk factors included being female, younger, less educated, unmarried and having a mental disorder. Interestingly, the strongest diagnostic risk factors were mood disorders in high-income countries but impulse control disorders in low- and middle-income countries.
Conclusion
There is cross-national variability in the prevalence of suicidal behaviours, but strong consistency in the characteristics and risk factors for these behaviours. These findings have significant implications for the prediction and prevention of suicidal behaviours.
Anomalous growth of silicon (Si) nanocrystals (NCs) was observed during Raman scattering measurements of nanosilica SiOx (x=0.9) powder with an average diameter of 40 nm. It was found that Si NCs were formed by exposure to the laser beam. This photo-assisted synthesis is similar to the thermal synthesis of Si NCs, which forms Si NCs by thermally decomposing SiOx into Si and SiO2. However, the photo-assisted synthesis is more effective in forming Si NCs than the thermal synthesis. Even one second after irradiation of the nanosilica SiOx powder with laser, Si NCs with an average size of 5 nm were formed. The Si NC size increases with increasing the laser power and exposure time. It is interesting to observe a self-limited size for higher laser power and prolonged exposure. The photo-assisted synthesis of Si NCs is proved to be a promising technique with a wide range of applications in nanotechnology.
We prove the existence of a family of Travelling Wave (TW) solutions for a large class of scalar reaction-diffusion equations with degenerate, nonlinear diffusion coefficients and monostable nonlinear reaction terms. We also investigate stability. Specifically, we show that, as in the linear diffusion case [6], the slowest TW in the family yields the asymptotic rate of the propagation of disturbances from the unstable rest state in these systems. In addition, we give conditions on the reaction term and diffusion coefficient ensuring the existence of interfaces.
The effect of bait-delivered anthelmintic to reduce the prevalence of Echinococcus multilocularis in wild red foxes was evaluated in Koshimizu, in the eastern part of Hokkaido, Japan. The study area (200 km2) was divided into baited and non-baited sections. The anthelmintic baits were distributed around fox den sites in the baited section every month for 13 months. After 1 year of the anthelmintic bait distribution, the prevalence of E. multilocularis in foxes, evaluated either by the parasite egg examination (from 27.1 to 5.6%) or coproantigen ELISA (from 59.6 to 29.7%), decreased in the baited section contrasting to that in the non-baited section (parasite egg: from 18.8 to 24.2%; ELISA: from 41.9 to 45.8%). The prevalence of E. multilocularis in grey red-backed vole Clethrionomys rufocanus, caught around fox dens, born after bait distribution also decreased and was significantly lower than that in non-baited section. However, within the study periods, the coproantigen-positive rate in fox faeces sporadically increased, while egg-positive rate constantly decreased. Since coproantigen ELISA can detect pre-patent infection, this observation indicates that reinfection pressure in the baited section was still high even after the 13 months of anthelmintic bait distribution. Therefore, the bait distribution longer than our study period is required for the efficient control of E. multilocularis in wild red fox population.
Whole-genome scans have identified Dmo1 as a major quantitative trait locus (QTL) for obesity and dyslipidaemia in the Otsuka Long Evans Tokushima Fatty (OLETF) rat. We have produced congenic rats for the Dmo1 locus, using marker-assisted speed congenic protocols, enforced by selective removal of other QTL regions (QTL-marker-assisted counterselection), to efficiently transfer chromosomal segments from non-diabetic Fischer 344 (F344) rats into the OLETF background. In the third generation of congenic animals, we observed a substantial therapeutic effect of the Dmo1 locus on lipid metabolism, obesity control and plasma glucose homeostasis. We conclude that single-allele correction of an impaired genetic pathway can generate a substantial therapeutic effect, despite the complex polygenic nature of type II diabetic syndromes.
Two methods are employed in the gas evaporation technique to form Ge nanocrystals with the Si-passivated surface. One uses one boat with a SiGe alloy as a source, and the other uses two boats each with Si and Ge. As a result of characterization by the x-ray diffraction (XRD) measurement, Raman scattering and x-ray photoelectron spectroscopy (XPS), it is found that Ge nanocrystals with the Si-passivated surface were formed by coevaporation of Si and Ge from two boats, while SiGe alloy nanocrystals were formed by evaporation of the Si-Ge alloy source from one boat.
If $E$ is an elliptic curve over ${\bb Q}$, then let $E(D)$ denote the $D$-quadratic twist of $E$. It is conjectured that there are infinitely many primes $p$ for which $E(p)$ has rank 0, and that there are infinitely many primes $l$ for which $E(l)$ has positive rank. For some special curves $E$ we show that there is a set $S$ of primes $p$ with density $\frac{1}{3}$; for which if $D = \Pi_{pj}$ is a squarefree integer where $pj \in S$, then $E(D)$ has rank 0. In particular $E(p)$ has rank 0 for every $p \in S$. As an example let $E_1$ denote the curve\[E_1: y^2 = x^3 + 44x^2 -19360x + 1682384.\]Then its associated set of primes $S_1$ consists of the prime 11 and the primes $p$ for which the order of the reduction of $X0(11)$ modulo $p$ is odd. To obtain the general result we show for primes $p \in S$ that the rational factor of $L(E(p),1)$ is nonzero which implies that $E(p)$ has rank 0. These special values are related to surjective ${\bb Z}/2{\bb Z}$ Galois representations that are attached to modular forms. Another example of this result is given, and we conclude with some remarks regarding the existence of positive rank prime twists via polynomial identities.
Applying laser ablation technique, we have synthesized two types of SiO2 films that include nanometer-sized Si particles. One is synthesized by alternative deposition of Si nanoparticles layers and SiO2 layers. The synthesized film exhibits red photoluminescence (PL) with a peak energy below 1.5 eV. The other is synthesized by annealing at 1000°C of SiOx films, which are formed by laser ablation in diluted O2 gas. We find that there is a narrow range of composition for efficient red PL. Based on the experimental results, we tentatively discuss a possible model for the origin of the red PL.
Availability of tensilely strained GaInP/AIGaInP quantum well, which is essential to laser diodes operating at 635–650nm, is investigated by combining conventional and time-resolved photoluminescence measurements. It is found that optical characteristics are improved by introducing tensile strain into barrier layers in addition to well layers, while samples with unstrained or compressively strained barrier layers reveal inferior characteristics. Experimantal data indicate that these optical characteristics are not determined by interfacial stress, but by the energy band discontinuity between well and barrier layer.