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Children are a critical part of certain legal trials, such as cases involving child abuse and neglect, and especially in cases of child sexual abuse. It is common for the only evidence in these types of cases to be the statement of the child victims. Children’s decisions about if and when to disclose the abuse are affected by many factors, and delays in disclosure are common. Police, forensic interviewers, prosecutors, and other professionals make decisions about when and how to interview children, the accuracy/credibility of their statements, if a case will move forward, and if and how children will testify in court. In some courtrooms, children are given special accommodations (e.g., testifying through closed-circuit TV or being accompanied by a therapy dog). Decisions about evaluating children in these situations have implications for the safety of children and the protection of innocent adults. Future research and policy implications are discussed.
Serious illness conversations (SICs) can improve the experience and well-being of patients with advanced cancer. A structured Serious Illness Conversation Guide (SICG) has been shown to improve oncology patient outcomes but was developed and tested in a predominantly White population. To help address disparities in advanced cancer care, we aimed to assess the acceptability of the SICG among African Americans with advanced cancer and their clinicians.
Methods
A two-phase study conducted in Charleston, SC, included focus groups to gather perspectives on the SICG in Black Americans and a single-arm pilot study of a revised SICG with surveys and qualitative exit interviews to evaluate patient and clinician perspectives. We used descriptive analysis of survey results and thematic analysis of qualitative data.
Results
Community-based and patient focus group participants (N = 20) reported that a simulated conversation using an adapted SICG built connection, promoted control, and fostered consideration of religious faith and family. Black patients with advanced cancer (N = 23) reported that SICG-guided conversations were acceptable, helpful, and promoted conversations with loved ones. Oncologists found conversations feasible to implement and skill-building, and also identified opportunities for training and implementation that could support meeting the needs of their patients with low health literacy. An adapted SICG includes language to assess the strength and affirm the clinician–patient relationship.
Significance of results
An adapted structured communication tool to facilitate SIC, the SICG, appears acceptable to Black Americans with advanced cancer and seems feasible for use by oncology clinicians working with this population. Further testing in other marginalized populations may address disparities in advanced cancer care.
Contamination of raw milk by psychrotrophs can lead to the production of heat-resistant proteases and subsequent spoilage of UHT milk. Therefore, this research communication evaluated the effect of a pre-milking teat disinfectant (active components: L-(+)-lactic acid and salicylic acid) and a liner disinfectant (active components: peracetic acid and hydrogen peroxide) on the number of mesophilic and (proteolytic) psychrotrophic bacteria prior to milking. The teat orifices of 10 cows were sampled using a swabbing procedure before and after treatment with a pre-milking teat disinfectant on six subsequent days. On the teat orifices, there was a small but statistically significant decrease in the psychrotrophic bacterial counts between pre and post dipping. No differences were observed for the mesophilic bacterial counts and proteolytic active counts. Liners were also sampled using swabs pre and post disinfection. No statistically significant decrease in the bacterial counts was observed post liner disinfection, although there was a numerical decrease. Sixty-two percent of the proteolytic psychrotrophs were pseudomonads: 16.5% of which were P. fragi, 14.3% P. lundensis, 10.0% P. fluorescens and 2.9% P. putida. Trinitrobenzenesulfonic acid (TNBS) analysis revealed a wide variety in proteolytic activity (from 0 to 55 µmol glycine/ml milk) and the presence of high producers. It can be concluded that there was only a minor effect of teat and liner disinfection on the psychrotrophic bacterial counts indicating that the measures presented did not result in a reduction of the targeted bacteria on teat orifices and liners.
Child maltreatment has been associated with various cumulative risk factors. However, little is known about the extent to which genetic and environmental factors contribute to individual differences between parents in perpetrating child maltreatment. To estimate the relative contribution of genetic and environmental factors to perpetrating maltreatment we used a parent-based extended family design. Child-reported perpetrated maltreatment was available for 556 parents (283 women) from 63 families. To explore reporter effects (i.e., child perspective on maltreatment), child reports were compared to multi-informant reports. Based on polygenic model analyses, most of the variance related to the perpetration of physical abuse and emotional neglect was explained by common environmental factors (physical abuse: c2 = 59%, SE = 12%, p = .006; emotional neglect: c2 = 47%, SE = 8%, p < .001) whereas genetic factors did not significantly contribute to the model. For perpetrated emotional abuse, in contrast, genetic factors did significantly contribute to perpetrated emotional abuse (h2 = 33%, SE = 8%, p < .001), whereas common environment factors did not. Multi-informant reports led to similar estimates of genetic and common environmental effects on all measures except for emotional abuse, where a multi-informant approach yielded higher estimates of the common environmental effects. Overall, estimates of unique environment, including measurement error, were lower using multi-informant reports. In conclusion, our findings suggest that genetic pathways play a significant role in perpetrating emotional abuse, while physical abuse and emotional neglect are transmitted primarily through common environmental factors. These findings imply that interventions may need to target different mechanisms dependings on maltreatment type.
Because of the national conversation about her status as a role model, the former First Lady of the United States (FLOTUS) presents an opportunity to analyze an Obama effect—particularly, the idea that Michelle Obama's prominence as a political figure can influence, among other things, citizens’ impressions of black women in America. Using evidence from the 2011 Henry J. Kaiser Family Foundation/Washington Post survey, we demonstrate that Michelle Obama's status as a role model operates as a “moderated mediator”: it transmits the effect of the former FLOTUS’ media activities to respondents’ racial attitudes, and the degree to which role model status functions as a mediating variable differs by race (and, to a lesser degree, by gender). Thus, our research provides both a theoretical and an empirical contribution to the Obama-effect literature.
We aimed to explore multiple perspectives regarding barriers to and facilitators of advance care planning (ACP) among African Americans to identify similarities or differences that might have clinical implications.
Method
Qualitative study with health disparities experts (n = 5), community members (n = 9), and seriously ill African American patients and caregivers (n = 11). Using template analysis, interviews were coded to identify intrapersonal, interpersonal, and systems-level themes in accordance with a social ecological framework.
Result
Participants identified seven primary factors that influence ACP for African Americans: religion and spirituality; trust and mistrust; family relationships and experiences; patient-clinician relationships; prognostic communication, care preferences, and preparation and control. These influences echo those described in the existing literature; however, our data highlight consistent differences by group in the degree to which these factors positively or negatively affect ACP. Expert participants reinforced common themes from the literature, for example, that African Americans were not interested in prognostic information because of mistrust and religion. Seriously ill patients were more likely to express trust in their clinicians and to desire prognostic communication; they and community members expressed a desire to prepare for and control the end of life. Religious belief did not appear to negate these desires.
Significance of results
The literature on ACP in African Americans may not accurately reflect the experience of seriously ill African Americans. What are commonly understood as barriers to ACP may in fact not be. We propose reframing stereotypical barriers to ACP, such as religion and spirituality, or family, as cultural assets that should be engaged to enhance ACP. Although further research can inform best practices for engaging African American patients in ACP, findings suggest that respectful, rapport-building communication may facilitate ACP. Clinicians are encouraged to engage in early ACP using respectful and rapport building communication practices, including open-ended questions.
The degree and longevity of quackgrass [Agropyron repens (L.) Beauv.] control provided by autumn applications of pronamide [3,5-dichloro(N-1,1-dimethyl-2-propynyl)benzamide] was influenced greatly by alfalfa (Medicago sativa L.) stand density, as well as by rate of application and soil type. When applications were made to a field with a sparse alfalfa stand (10 to 20 crowns/m2), quackgrass yields were reduced the year following pronamide application, but quackgrass reinfested the plots the second year after treatment. Quackgrass yields one and two seasons following autumn treatment with 2.2 kg/ha pronamide were 1480 and 3890 kg/ha compared to 4480 and 4870 kg/ha for control plots. Annual applications of pronamide were necessary to maintain quackgrass control in the sparse alfalfa stand. Pronamide application to a vigorous, dense alfalfa stand (40 to 50 crowns/m2) provided quackgrass control which persisted into the second year after treatment. Quackgrass control ratings one and two seasons after application of 1.1 kg/ha pronamide were 100 and 90%. Pronamide treatments reduced first cutting quackgrass yields, and increased first cutting alfalfa yields. Treatment of the sparse alfalfa stand with 2.2 kg/ha pronamide resulted in first cutting alfalfa and quackgrass yields of 2420 and 990 kg/ha compared to 1430 and 3940 kg/ha for controls. Treatment of a dense alfalfa stand with 1.1 kg/ha pronamide resulted in first cutting alfalfa and quackgrass yields of 3850 and 300 kg/ha compared to 1710 and 1660 kg/ha for controls. Total herbage yields from all cuttings were either slightly decreased when fields with sparse alfalfa stands were treated or remained constant or slightly increased when more dense alfalfa stands were treated. Pronamide applied with potash as the carrier was as effective as when applied in water. Pronamide treatment resulted in increased crude protein concentration in first cutting herbage at all locations in all years. Crude protein concentration in first cutting control herbage ranged from 13.3 to 16.1%. Crude protein concentration in first cutting herbage from plots treated with 1.1 kg/ha pronamide ranged from 17.7 to 20.6%, depending on year and location. In vitro digestible dry matter (IVDDM) concentrations were increased by most rates of pronamide in first, second, and third cutting herbage. IVDDM for first cutting control herbage was 51.4% compared to 61.3% for herbage treated with 2.2 kg/ha pronamide. Acid detergent fiber concentration in first cutting herbage was not affected by pronamide.
The current study compared beef production, quality and fatty acid (FA) profiles of yearling steers fed a control diet containing 70 : 30 red clover silage (RCS) : barley-based concentrate, a diet containing 11% sunflower seed (SS) substituted for barley, and diets containing SS with15% or 30% wheat dried distillers’ grain with solubles (DDGS). Additions of DDGS were balanced by reductions in RCS and SS to maintain crude fat levels in diets. A total of two pens of eight animals were fed per diet for an average period of 208 days. Relative to the control diet, feeding the SS diet increased (P<0.05) average daily gain, final live weight and proportions of total n-6 FA, non-conjugated 18:2 biohydrogenation products (i.e. atypical dienes) with the first double bond at carbon 8 or 9 from the carboxyl end, conjugated linoleic acid isomers with the first double bond from carbon 7 to 10 from the carboxyl end, t-18:1 isomers, and reduced (P<0.05) the proportions of total n-3 FA, conjugated linolenic acids, branched-chain FA, odd-chain FA and 16:0. Feeding DDGS-15 and DDGS-30 diets v. the SS diet further increased (P<0.05) average daily gains, final live weight, carcass weight, hot dressing percentage, fat thickness, rib-eye muscle area, and improved instrumental and sensory panel meat tenderness. However, in general feeding DGGS-15 or DDGS-30 diets did not change FA proportions relative to feeding the SS diet. Overall, adding SS to a RCS-based diet enhanced muscle proportions of 18:2n-6 biohydrogenation products, and further substitutions of DDGS in the diet improved beef production, and quality while maintaining proportions of potentially functional bioactive FA including vaccenic and rumenic acids.
Education in post-colonial African nations has served as the apparatus for sustaining and accelerating overall development, for increasing political and social awareness, and for providing a cadre of highly trained indigenous manpower to implement, manage, and administer ambitious national development strategies. To understand the process and impact of an educational system, however, one must be cognizant of exogenous forces. From a structuralist frame of reference, Apple (1975) asserts that researchers must examine the power and control external to the educational system, thus making political and economic decisions an integral part of an educational investigation. Scribner (1970) argues that researchers cannot avoid the effects of political demands on the changes in the educational system.
The relationship among educational systems and variables in the social, economic, and political systems in which education exists have been well studied in the comparative education literature (Apple, 1975; Arrighi and Saul, 1973; Dasgupta, 1974; Jolly, 1969; Mazrui, 1978; Morrison, 1976; Simmons, 1974; Simmons and Alexander, 1975). However, the outcomes of the relationship between politics and higher education in post-colonial Africa have not been documented extensively. This paper helps to remedy this deficiency by examining the functional relationship between the national level of leadership in Tanzania and the nation's only university, the University of Dar es Salaam. Julius K. Nyerere, the President of Tanzania since its inception, and the ruling party have attempted to accomplish decolonization, restructure the educational system, and promote rural development
The present study examined the specificity of autobiographical memory in adolescents and adults with versus without child sexual abuse (CSA) histories. Eighty-five participants, approximately half of whom per age group had experienced CSA, were tested on the Autobiographical Memory Interview. Individual difference measures, including those for trauma-related psychopathology, were also administered. Findings revealed developmental differences in the relation between autobiographical memory specificity and CSA. Even with depression statistically controlled, reduced memory specificity in CSA victims relative to controls was observed among adolescents but not among adults. A higher number of posttraumatic stress disorder criteria met predicted more specific childhood memories in participants who reported CSA as their most traumatic life event. These findings contribute to the scientific understanding of childhood trauma and autobiographical memory functioning and underscore the importance of considering the role of age and degree of traumatization within the study of autobiographical memory.
Exposure to intrauterine growth restriction (IUGR) is an important risk factor for impaired learning and memory, particularly in males. Although the basis of IUGR-associated learning and memory dysfunction is unknown, potential molecular participants may be insulin-like growth factor 1 (Igf1) and its receptor, IGF1r. We hypothesized that transcript levels and protein abundance of Igf1 and IGF1r in the hippocampus, a brain region critical for learning and memory, would be lower in IUGR male rats than in age-matched male controls at birth (postnatal day 0, P0), at weaning (P21) and adulthood (P120). We also hypothesized that changes in messenger Ribonucleic acid (mRNA) transcript levels and protein abundance would be associated with specific histone marks in IUGR male rats. Lastly, we hypothesized that IUGR male rats would perform poorer on tests of hippocampal function at P120. IUGR was induced by bilateral ligation of the uterine arteries in pregnant dams at embryonic day 19 (term is 21 days). Hippocampal Igf1 mRNA transcript levels and protein abundance were unchanged in IUGR male rats at P0, P21 or P120. At P0 and P120, IGF1r expression was increased in IUGR male rats. At P21, IGF1r expression was decreased in IUGR male rats. Increased IGF1r expression was associated with more histone 3 lysine 4 dimethylation (H3K4Me2) in the promoter region. In addition, IUGR male rats performed poorer on intermediate-term spatial working memory testing at P120. We speculate that altered IGF1r expression in the hippocampus of IUGR male rats may play a role in learning and memory dysfunction later in life.
The aim of the present study was to assess the recent trends in the epidemiology of non-typhoid Salmonella in Israel using a sentinel laboratory-based surveillance network. Between 1999 and 2009, 8758 Salmonella stool isolates were reported by five sentinel laboratories. There was a significant decrease in the incidence rate of Salmonella isolates from 70·5/100 000 in 1999 to 21·6/100 000 in 2005 followed by a slight increase to 30·3/100 000 in 2009. Of all Salmonella, 64·3% were isolated from children in the 0–4 years age group. Up to 2008, S. Enteritidis was the most prevalent serotype and in 2009 S. Infantis emerged as the most common Salmonella serotype. The decrease in the incidence of S. Enteritidis and S. Typhimurium and increase in S. Infantis among humans were associated with a similar trend among breeding flocks, which followed significant preventive interventions conducted against S. Enteritidis and S. Typhimurium infections in poultry. Tight surveillance and education of food handlers and consumers should be enhanced to reduce the foodborne transmission of Salmonella in Israel.
The purpose of the present research was to examine Deese–Roediger–McDermott false memory for trauma-related and nontrauma-related lists in adolescents and adults with and without documented histories of child sexual abuse (CSA). Individual differences in psychopathology and adult attachment were also explored. Participants were administered free recall and recognition tests after hearing CSA, negative, neutral, and positive Deese–Roediger–McDermott lists. In free recall, CSA and negative lists produced the most false memory. In sharp contrast, for recognition, CSA lists enjoyed the highest d′ scores. CSA-group adolescents who evinced greater posttraumatic stress disorder (PTSD) symptoms had higher rates of false memory compared to (a) non-CSA group adolescents with higher PTSD symptom scores (free recall), and (b) CSA-group adolescents with lower PTSD symptom scores (recognition). Regression analyses revealed that individuals with higher PTSD scores and greater fearful-avoidant attachment tendencies showed less proficient memory monitoring for CSA lists. Implications for trauma and memory development and for translational research are discussed.
Early results from the SAGE-SMC (Surveying the Agents of Galaxy Evolution in the tidally-disrupted, low-metallicity Small Magellanic Cloud) Spitzer legacy program are presented. These early results concentrate on the SAGE-SMC MIPS observations of the SMC Tail region. This region is the high H i column density portion of the Magellanic Bridge adjacent to the SMC Wing. We detect infrared dust emission and measure the gas-to-dust ratio in the SMC Tail and find it similar to that of the SMC Body. In addition, we find two embedded cluster regions that are resolved into multiple sources at all MIPS wavelengths.
Verbal learning and memory deficits are frequent among patients with schizophrenia and correlate with reduced magnetic resonance imaging (MRI) volumes of the hippocampus in these patients. A crucial question is the extent to which interrelated structural-functional deficits of the hippocampus reflect a vulnerability to schizophrenia, as opposed to the disorder per se.
Method
We combined brain structural measures and the Rey Auditory Verbal Learning Test (RAVLT) to assess hippocampal structure and function in 36 never-medicated individuals suspected to be in early (EPS) or late prodromal states (LPS) of schizophrenia relative to 30 healthy controls.
Results
Group comparisons revealed bilaterally reduced MRI hippocampal volumes in both EPS and LPS subjects. In LPS subjects but not in EPS subjects, these reductions were correlated with poorer performance in RAVLT delayed recall.
Conclusions
Our findings suggest progressive and interrelated structural-functional pathology of the hippocampus, as prodromal symptoms and behaviours accumulate, and the level of risk for psychosis increases. Given the inverse correlation of learning and memory deficits with social and vocational functioning in established schizophrenia, our findings substantiate the rationale for developing preventive treatment strategies that maintain cognitive capacities in the at-risk mental state.
We are performing a uniform and unbiased imaging survey of the Large Magellanic Cloud (LMC), using the IRAC and MIPS instruments on board the Spitzer Space Telescope (Spitzer). Meixner et al. (2006) provides an overview of the project and initial results and their Table 1 (repeated here) outlines the survey's salient characteristics. In this project, we are surveying the agents of a galaxys evolution (SAGE), i.e. the interstellar medium (ISM) and stars, and their interaction on the galaxy wide scale of the LMC. Spitzer IRAC and MIPS images provide key insights into the life cycle of matter in a galaxy because the infrared emission from dust grains is an effective tracer of the ISM, star formation, and stellar mass-loss. Three key science goals determined the coverage and depth of the survey. The detection of diffuse ISM with column densities > 1.2×1021 H cm−2 permits detailed studies of dust processes in the ISM. SAGE's point source sensitivity enables a complete census of newly formed stars with masses >3 M⊙ that will determine the current star formation rate in the LMC. SAGE's detection of evolved stars with mass loss rates > 10−8 M⊙ yr−1 will quantify the rate at which evolved stars inject mass into the ISM of the LMC (Blum et al. 2006). The SAGE data are nonproprietary. The preliminary SAGE catalog of epoch 1 photometry, prepared by the SAGE Team and released to the public on January 3, 2006, contains over 4 million IRAC sources, band merged with 2MASS photometry and over 60,000 MIPS 24 micron sources. Preliminary estimates indicate that foreground Milky Way stars and background galaxies may comprise as much as 18% and 12%, respectively, of these catalogs. To learn more about the SAGE project: http://sage.stsci.edu/.
It has been observed experimentally that small bubbles in pure liquids can be held stationary or driven downwards by means of a sufficiently strong negative temperature gradient in the vertical direction. This effect is demonstrated to be due to the stresses resulting from the thermal variation of surface tension at the bubble surface. The flow field within and around the bubble is derived, and an expression for the magnitude of the temperature gradient required to hold the bubble stationary is obtained. This expression is verified experimentally.