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This chapter discusses the history and evolution of international intellectual property rights (IPRs) protection, focusing on the Trade-Related Aspects of Intellectual Property Rights (TRIPS) Agreement. It examines the justifications for and debates surrounding the extension of developed country-style IPRs to developing nations, as well as the TRIPS provisions themselves. The chapter also addresses the conflicts between TRIPS and other international regimes, such as the Convention on Biological Diversity, and the significant public health concerns raised by TRIPS, particularly regarding access to essential medicines. Finally, it concludes by analysing the distributive impact of TRIPS and the challenges posed by emerging technologies like artificial intelligence.
This chapter examines the complex relationship between international trade law and public health. While trade liberalisation can lower the cost of medical supplies and raise global standards of living, trade rules also constrain national public health measures and can facilitate trade in harmful products. The chapter analyses how the World Trade Organization (WTO) has addressed health-related trade restrictions, including disputes over tobacco, alcohol, and asbestos. It also explores the tension between intellectual property rights and access to essential medicines, as well as the impact of trade on healthcare supply chains, particularly during the Covid-19 pandemic. The chapter concludes by critiquing the WTO’s ‘exceptionalism’ framework for evaluating public health measures and arguing for a more integrated approach that prioritises both health and economic resilience.
This is the first of three overview chapters examining pivotal moments in the history of the League of Red Cross Societies. The chapter offers insights into the origins of the League and how the challenges it faced in its first decade determined the shape of the world’s first international humanitarian network dedicated to improving global health and coordinating peacetime relief efforts. The chapter argues that the massive destruction wrought by the First World War opened new areas of humanitarian endeavour for the Red Cross movement, especially in public health, social welfare, and the eradication of diseases and the administration of disaster relief. During the 1920s, the League forged a form of ‘resilient humanitarianism’, marked by agility and an ability to adapt to changing conditions and circumstances.
Chapter 3 focuses on the medical and public health work that Sheppard-Towner agents did at the state and county levels. This work included traveling health clinics, better baby contests, home visiting, and midwife training and regulation. It shows how critical Sheppard-Towner state agents were to both making rural populations visible and legible to the state and to making state bureaus and programs more visible and legible to rural populations. As they went county to county and door to door, state public health doctors and nurses, tried to adapt to the variable circumstances they encountered. Sometimes, they enticed rural families with entertaining spectacles. Other times, they relied on coercive methods, including threats and intimidation, especially with African American and Native American women. In both cases, they made themselves and their agencies known to rural Americans.
This chapter examines the ambitions of the League of Red Cross Societies to co-ordinate the global fight against venereal diseases (VD) from 1919 to the early 1930s. VD had preoccupied the agendas of both national and international organisations for decades prior to the explosion of infections during the First World War. As an international body formed to engage in public health, the League took on VD as a central area of its work in the interwar period. The chapter explores the programmes of work identified by the League as it attempted to consolidate existing activities to limit the effects and spread of VD, and how it worked with National Red Cross and Red Crescent Societies around the world and other institutions and governments to prevent its spread. This included the organisation of multiple conferences, the dissemination of propaganda literature to educate people about VD, and the exchange of films across the Red Cross movement. The chapter demonstrates that the global fight against venereal diseases was one in which the efforts of the League were largely successful.
The introductory chapter provides an overview of the book, Resilient Humanitarianism, and important contextual information for readers about the history of the League of Red Cross Societies, now the International Federation of Red Cross and Red Crescent Societies (IFRC), the world’s largest humanitarian and volunteer network made up of Red Cross and Red Crescent National Societies from around the world. The League was established in 1919 to complement the work of the ICRC during peacetime. The League’s focus was on the improvement of public health, the prevention of disease and the mitigation of suffering. The chapter includes a discussion of characteristics of the League that helps to explain its longevity and its resilient humanitarianism. These include governance structures, how networks were assembled, ruptures and crises, innovation, capacity for development, and principles and values.
Missed hospital appointments (Do Not Attend [DNAs]) undermine healthcare efficiency and access. A high-profile study found that adding descriptive social norms (DSNs) or specific institutional cost (SIC) messages to SMS reminders could substantially reduce DNAs. This prompts optimism that integrating behavioural insights, besides reminders themselves, offers a cost-effective approach to mitigate DNAs. However, subsequent similar interventions have reported heterogeneous findings, echoing broader debates on recent meta-analyses about how to evaluate such findings. We address this issue by framing Behavioural Insights as Applied Science, which structures validation in three phases inspired by clinical research. We treat the aforementioned study as a Phase 1 proof of concept and conduct a Phase 2 replication under comparable operational conditions in a quasi-experimental, time-blocked field trial at South-western Jutland Hospital (20,867 appointments) across Cardiology, Endocrinology and Pulmonology. Patients received SMS reminders rotating every 2 months between a standard message, DSN framing or SIC framing. Neither DSN nor SIC reduced DNAs overall. SIC increased cancellations (OR = 1.41, p < 0.001) but not DNAs; DSN reduced DNAs in Cardiology (OR = 0.76, p = 0.027), while SIC increased DNAs in Endocrinology (OR = 1.31, p = 0.021). Our findings underscore the importance of applying a systematic approach in the evaluation of Behavioural Insights.
To examine systemic challenges to health system resilience in Puerto Rico following Hurricane Maria, focusing on resource, management, and policy domains.
Methods
Semi-structured interviews (n = 62) were conducted from January to April 2023 with health care professionals, patients, community leaders, nonprofits, and government stakeholders using purposive sampling. Interviews were conducted in Spanish, transcribed, translated, and thematically analyzed.
Results
Resource failures centered on prolonged power outages (mean 62.7 days; up to 300 days), which cascaded into water, transport, and communication breakdowns. These disruptions endangered patients through interrupted surgeries, inoperable imaging, oxygen shortages, and infection control failures. Management challenges included depleted stockpiles, staff burnout, and workforce migration, which extended wait times to 6-8 months. Coordination was inconsistent, with duplication of aid in some areas and neglect in others, while top-down governance slowed response. Policy constraints compounded vulnerabilities: health insurance pre-authorizations delayed urgent care, capped Medicaid funds, and lack of federal parity, limited preparedness, and centralized aid distribution left rural communities underserved.
Conclusions
Puerto Rico’s health system resilience was undermined by interdependent failures across infrastructure, management, and policy. Building resilience will require investment in decentralized power, reforms to emergency insurance protocols, stronger inter-agency coordination, and equitable federal financing to ensure preparedness for future climate-related disasters.
Edited by
Liz McDonald, East London NHS Foundation Trust,Roch Cantwell, Perinatal Mental Health Service and West of Scotland Mother & Baby Unit,Ian Jones, Cardiff University
Postpartum psychosis is a condition of great clinical and public health importance. Severe episodes of mental illness in the perinatal period can result in significant distress, may disrupt the developing relationship between mother and child, and have long-term implications for the well-being of the woman, her baby, family and wider society.
In this chapter we will discuss what we know about this condition and its relationship to bipolar disorder, how it might best be defined, what we still need to find out, and consider how it should be managed.
Hazardous materials (HazMat) incidents pose significant risks to public health, safety, and the environment. This study aimed to characterize the temporal trends, geographic distribution, operational settings, and incident types of HazMat events reported in Oman.
Methods
This retrospective descriptive study analyzed data from the national HazMat incident records maintained by the Civil Defence and Ambulance Authority (CDAA). All reported chemical, biological, or radiological incidents between June 1, 2019, and November 30, 2024, were included.
Results
A total of 55 HazMat incidents were recorded during the study period. Reported incidents increased over time, with the highest annual counts observed in 2023 (14 incidents) and 2024 (17 incidents). Muscat Governorate accounted for 39 incidents (71%). Residential neighborhoods were the most common operational setting (26/55, 47%), followed by other public areas (9/55, 16%), while airports, educational institutions, industrial areas, and transportation corridors each accounted for 5 incidents (9%). Gas leaks were the most frequently reported incident type, involved in 28 incidents (51%).
Conclusions
HazMat incidents in Oman increased over the study period and were concentrated in Muscat Governorate. Incidents occurred across diverse operational settings, particularly residential and public environments, while gas leaks represented the most frequently reported incident type.
Processes of repression, criminalization and penalization were importantly affected by the COVID-19 pandemic. Mobilizing data produced through an ethnographic study of plea courts in Ottawa, this article reports on the ways in which lower criminal courts administered what judges described as “COVID justice.” In this transitory form of justice, we observed a) a dilated reward system for guilty pleas; b) the work of the virtual resolution team, a workgroup dedicated to unburdening the courts from backlogs attributed to the pandemic; c) requests to increase the credits granted for time served in locked-down, noxious prisons, and; d) the diversion of sentenced individuals from prison on the grounds of the primacy of public health over criminal justice.
Chronic stress can lead to physical and mental health conditions. This study aimed to identify the different stress profiles and stress relief methods among Filipinos living in the Philippines using latent class analysis. A secondary analysis of a cross-sectional study was employed in this study. The stressors and stress-relief practices among Filipinos were investigated using the I-HEART-FILIPINOS data set. Latent class analysis was used to identify the different profiles of stress causes and management methods among 1,196 Filipinos residing in the Philippines, specifically the Northern Luzon area. Four stress-related profiles were identified: (1) low financial stress relieved by eating and exercise; (2) work-related stress relieved by self-care; (3) familial and economic turmoil relieved by eating, exercise and prayer; (4) high financial stress relieved by staying at home and remaining indoors. The four-class solution explained 58% of the variation in the data through classification. Disparities were observed between classes in terms of emotional distress and sociodemographic variables, implying how sociocultural factors could affect stress presentation and management in Filipinos. The findings of this study inform the development of stress management interventions specifically designed to address the needs of underserved populations in the Philippines and neighboring countries to improve overall health.
Violence against health workers and health care facilities in conflict settings is a major public health concern, disrupting service delivery and undermining humanitarian response. While attacks on health care have been widely documented, standardized multicountry comparisons using consistent surveillance metrics remain limited.
Methods
A retrospective, descriptive observational analysis was conducted using incident-level, open-source records curated on the United Nations Humanitarian Data Exchange (HDX) from 2016 to 2024, covering 20 conflict-affected settings. Incidents involving harm to aid and health workers and attacks on health care facilities were summarized descriptively and standardized per capita to enable cross-setting comparison.
Results
Across the 20 settings, reported harm to health systems increased after 2021. PSE exhibited the highest per-capita burden, with 407 aid and health-worker fatalities and 420 reported attacks on health care facilities, while Ukraine recorded the highest absolute number of facility attacks (1,060). Myanmar demonstrated a distinct pattern characterized by large-scale arrests of health care workers following the 2021 military coup. Other settings demonstrated variable burdens and harm modalities, including personnel-lethal, infrastructure-destructive, and coercive patterns.
Conclusions
Reported attacks on health care in conflict settings are widespread and heterogeneous. This descriptive, per-capita comparison highlights variability in harm modalities across settings and identifies high-burden contexts that may warrant prioritization for surveillance strengthening, preparedness planning, and protection-focused operational coordination. Further research is needed to examine drivers, impacts on service delivery, and prevention strategies using attribution-aware, mixed-methods approaches.
This article explores possible connections between health crises, economic policy choices, and the rise of populist movements, drawing on evidence from the interwar period. It considers how differing policy responses to the Great Depression may have been associated with contrasting trajectories in both public health and political developments. In Germany, the adoption of austerity measures in the early 1930s appears to have coincided with worsening economic conditions, declining health indicators, and growing electoral support for far-right movements. By contrast, expansionary initiatives introduced under the New Deal in the U.S. were likely accompanied by strengthened social protections, improvements in health outcomes, and what some observers have interpreted as a mitigation of pressures toward political radicalisation. Taken together, these historical experiences offer insights into contemporary developments, where perceived inadequacies in responding to intertwined health and economic crises could potentially contribute to eroding institutional trust and increasing receptiveness to populist narratives.
Conducting health systems assessments helps highlight weaknesses and strengths to be explored to improve care delivery. The Assessment of Chronic Illness Care (ACIC) considers the perspective of professionals who work in the care-providing institution. Its structure comprises seven dimensions that provide specific data about the care offered. Objectives: (1) evaluate the institutional capacity for Type 2 Diabetes Mellitus (T2DM) management in the interior of the State of Amazonas from the perspective of health professionals; (2) verify the association between socio-educational, work and geographic location variables with the dimensions of the ACIC.
Methods:
A cross-sectional study carried out between October 2020 and December 2022 in 36 Primary Health Units (PHUs) of the seven cities of the Amazonas, totaling 230 participants. Excel 2019 and R (4.2.1) were used for data analysis. The association between independent variables and ACIC dimensions was analyzed using multiple logistic regression analysis.
Result:
The PHUs in the rural Amazonas have the basic capacity to care for patients with T2DM. Analysis of each dimension of the ACIC demonstrated that geographic location was the most relevant factor, showing an association with all instrument dimensions.
Conclusions:
Socioeducational variables showed an association with the dimensions of Decision Support, Design of the Service Delivery System, Clinical Information System, and Integration of components of the Care Model for Chronic Conditions. Work-related variables, on the other hand, were associated with the dimensions of Organization of Health Care, Community Resources, Support for Self-Management and Integration of the components of the Chronic Conditions Care Model.
In the first independent study of the League of Red Cross Societies, an interdisciplinary team of leading scholars examine its history, and how it influenced twentieth-century humanitarianism. They explore how the League evolved from 1919 to 1991 as a peacetime organisation of the Red Cross in contrast to the original wartime focus of the International Committee of the Red Cross. Investigating largely unknown, but significant actors, they shed new light on the League's activities in Southeast Asia, the Horn of Africa, Latin America and Europe through case studies focussing on its global health initiatives, the complexity of its networks in war and peace, and its role in providing relief. The authors argue that it is impossible to understand today's Red Cross and Red Crescent movement and global humanitarianism without considering the structures, expertise and training provided by the League to member National Societies from 1919 to 1991.
This article, which relies on underutilized archival collections as well as oral histories, is one of the first comprehensive examinations of the feminist struggle to decriminalize abortion during Brazil’s transition to democracy during the 1980s. We discuss how the consolidation of the antiabortion Christian right and its proximity to several political parties, including ones on the left, coupled with the politically moderate tone of the transition from dictatorship to democracy, constrained the space in which Brazilian feminists could make radical demands of the state. Moreover, we contend that although the creation of the state-funded feminist organ Conselho Nacional dos Direitos da Mulher in 1985 brought important visibility to feminist issues and inserted the movement’s agenda squarely within the government apparatus, it also fragmented feminists, threatened co-optation by the state, and ultimately compelled abortion rights activists to prioritize the more palatable strategy of expanding access to therapeutic abortions, which were already permitted by law. In addition to divergences in political strategy, feminists struggled to create multiracial and multiclass coalitions during this period, when many Black feminists and working-class women were organizing around other concerns. As a result, feminists were not able to fundamentally alter public opinion about the political importance of abortion, and their efforts to enshrine the termination of pregnancy as a human right in the 1988 Constitution were unsuccessful.
The gambling industry tends to frame gambling harms as a matter of personal responsibility, which is implicit in their messages like ‘gamble responsibly’ or ‘take time to think’. Jurisdictions such as Australia and the UK are replacing industry messages with a range of independently designed ones, like in tobacco warning labels. Counter-industry messages have been proposed to challenge industry narratives, e.g., ‘gambling products are designed to be addictive’. Here we tested 10 potential counter-industry messages among UK gamblers (N = 4,094) using a mixed-methods approach. Results showed that the three best-performing messages came from existing counter-industry campaigns. Participants believed the messages and agreed that they were relevant to people experiencing gambling harm. Participants experiencing higher levels of harm tended to see the messages as more personally relevant to them. Free-text analysis showed that ‘gambling products are designed to be addictive’ received the most positive responses, and also that personal responsibility views were widespread among participants. Messages randomly shown later in the experiment were appraised more positively, suggesting that counter-industry messaging may become more effective when its core message is repeated in multiple ways. Continual design and testing will contribute to the development of best approaches and inform future implementation.
Despite variation in their social needs and experiences, all humans require social connections to thrive. When humans lack fulfilling connections, they experience loneliness. However, while seemingly simple, loneliness is a multidimensional construct arising from varied social deficiencies and leading to varied psychological experiences. This chapter reviews the literature on loneliness, describing what it is, why we experience it, its prevalence and consequences, and what is being done globally to address it. In doing so, we highlight the considerable impacts of loneliness on individuals and society, its complexity, and the opportunities for future work. We close acknowledging the significant advancements made in loneliness research over the past several decades and highlight how this knowledge is being mobilized to advance the prevention and treatment of loneliness. In doing so, we hope this chapter serves as a useful starting point for understanding the problem of loneliness and the challenge of addressing it.
Public health research faces challenges in recruiting socio-economically disadvantaged groups. This study evaluated whether machine learning (ML) algorithms developed using data from a general population could predict indices of diet quality among a socio-economically disadvantaged group. Data from 5367 adults (77·5 % females) in the NutriQuébec project and on 122 variables potentially associated with dietary intakes were used. Dietary intakes were measured using a web-based 24-h recall. Participants were categorised by fifths of a deprivation score based on income, education and material and social deprivation. Participants in the first four fifths formed the general NutriQuébec sample (n 4180) and those above the fifth quintile formed the high deprivation sample (n 1187). Three indices of diet quality defined as ‘high’ or ‘low’ were used: vegetable and fruit consumption (VFC, ≥ 5·0 reference amounts (RA)/d), ‘other foods’ consumption, meaning, foods not recommended in Canada’s Food Guide 2019 (OFC, > 5·0 RA/d) and overall diet quality measured using the Healthy Eating Food Index-2019 (HEFI-2019, > 48·9 points). The algorithms developed and tested in the general NutriQuébec sample predicted high VFC, OFC and HEFI-2019 with accuracies of 0·60 (95 % CI 0·58, 0·62), 0·58 (95 % CI 0·56, 0·60) and 0·61 (95 % CI 0·59, 0·63), respectively. In the high deprivation sample, the algorithms predicted the diet quality indices with comparable accuracies (VFC, 0·69, 95 % CI 0·67, 0·71; OFC, 0·56, 95 % CI 0·54, 0·58; HEFI-2019, 0·66, 95 % CI 0·65, 0·67). ML algorithms trained to predict three diet quality indices in the general NutriQuébec sample were applicable to a high deprivation group.