Skip to main content Accessibility help
×
Hostname: page-component-76fb5796d-5g6vh Total loading time: 0 Render date: 2024-04-27T06:26:49.268Z Has data issue: false hasContentIssue false

VIII.140 - Tetany

from Part VIII - Major Human Diseases Past and Present

Published online by Cambridge University Press:  28 March 2008

Kenneth F. Kiple
Affiliation:
Bowling Green State University, Ohio
Get access

Summary

Tetany is a symptom complex characterized by painful and prolonged contractions of the (generally smooth) muscles. These often appear as convulsions and are usually triggered by hypocalcemia. Adult varieties of the condition that result from calcium or magnesium deficiencies include maternal tetany, parathyroid tetany, osteomalacic tetany, and magnesium tetany. Alkalosis can also produce tetany. Examples include gastric tetany and hyperventilation tetany, following a lengthy period of forced inspiration and expiration. Another form of the disease – grass tetany caused by magnesium deficiency – is found in cattle. Despite these many forms, however, the disease occurs chiefly in infants (neonatal tetany) and young children (infantile tetany) in whom it is normally associated with rickets. It affects males far more than females and, in the absence of proper treatment, frequently proves deadly.

Distribution and Incidence

Because tetany has so often been confused with tetanus, very few data are available on the geographic distribution of the disease. It probably occurs worldwide in the temperate zones, with the highest frequency of neonatal tetany among bottle-fed, black, and prematurely born infants. An abundance of year-round sunshine and, hence, vitamin D may have the effect of reducing the incidence of infantile tetany in the tropics. The incidence of neonatal tetany recorded at New York Hospital between 1940 and 1958 was between 1 per 500 and 1 per 700 births.

Type
Chapter
Information
Publisher: Cambridge University Press
Print publication year: 1993

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

Beaton, G. H. 1976. Some other nutritional deficiencies. In Nutrition in preventive medicine, ed. Beaton, G. H. and Bengoa, J. M.. Geneva.Google Scholar
Bloomfield, Arthur. 1959. A bibliography of internal medicine: Tetany. Stanford Medical Bulletin 17.Google ScholarPubMed
Clarke, John. 1815. Commentaries on some of the most important diseases of children. London.Google Scholar
Clarke, Patrick, and Carré, I. J.. 1967. Hypocalcemic, hypermagnesemic convulsions. Journal of Pediatrics 5.Google Scholar
Cockburn, F., et al. 1973. Neonatal convulsions associated with primary disturbance. Archives of Diseases in Childhood 48.CrossRefGoogle ScholarPubMed
Hess, Alfred. 1929. Rickets including osteomalacia and tetany. Philadelphia.Google Scholar
Hirsch, August. 1883–6. Handbook of geographical and historical pathology, 3 vols., trans. Creighton, Charles. London.Google Scholar
Howland, J., and Marriott, W. McKim. 1918. Observations upon the calcium content of the blood in infantile tetany and upon the effect of treatment by calcium. Quarterly Journal of Medicine 2.Google Scholar
Keen, J. H. 1969. Significance of hypocalcemia in neonatal convulsions. Archives of Diseases in Childhood 44.CrossRefGoogle ScholarPubMed
Purvis, R. J., et al. 1973. Enamel hypoplasia of the teeth associated with neonatal tetany: A manifestation of maternal vitamin D deficiency. Lancet ii.Google Scholar
Saville, Paul D., and Kretchmer, Norman. 1960. Neonatal tetany: A report of 125 cases and review of the literature. Biology of the Neonate 2.Google ScholarPubMed
Tsang, Reginald, and Oh, William. 1970. Neonatal hypocalcemia in low birth weight infants. Pediatrics 45.Google ScholarPubMed

Save book to Kindle

To save this book to your Kindle, first ensure coreplatform@cambridge.org is added to your Approved Personal Document E-mail List under your Personal Document Settings on the Manage Your Content and Devices page of your Amazon account. Then enter the ‘name’ part of your Kindle email address below. Find out more about saving to your Kindle.

Note you can select to save to either the @free.kindle.com or @kindle.com variations. ‘@free.kindle.com’ emails are free but can only be saved to your device when it is connected to wi-fi. ‘@kindle.com’ emails can be delivered even when you are not connected to wi-fi, but note that service fees apply.

Find out more about the Kindle Personal Document Service.

  • Tetany
  • Edited by Kenneth F. Kiple, Bowling Green State University, Ohio
  • Book: The Cambridge World History of Human Disease
  • Online publication: 28 March 2008
  • Chapter DOI: https://doi.org/10.1017/CHOL9780521332866.202
Available formats
×

Save book to Dropbox

To save content items to your account, please confirm that you agree to abide by our usage policies. If this is the first time you use this feature, you will be asked to authorise Cambridge Core to connect with your account. Find out more about saving content to Dropbox.

  • Tetany
  • Edited by Kenneth F. Kiple, Bowling Green State University, Ohio
  • Book: The Cambridge World History of Human Disease
  • Online publication: 28 March 2008
  • Chapter DOI: https://doi.org/10.1017/CHOL9780521332866.202
Available formats
×

Save book to Google Drive

To save content items to your account, please confirm that you agree to abide by our usage policies. If this is the first time you use this feature, you will be asked to authorise Cambridge Core to connect with your account. Find out more about saving content to Google Drive.

  • Tetany
  • Edited by Kenneth F. Kiple, Bowling Green State University, Ohio
  • Book: The Cambridge World History of Human Disease
  • Online publication: 28 March 2008
  • Chapter DOI: https://doi.org/10.1017/CHOL9780521332866.202
Available formats
×