Book contents
- Frontmatter
- Contents
- List of contributors
- Preface
- Psychology, health and illness
- Medical topics
- Abortion
- Accidents and unintentional injuries
- Acne
- Alcohol abuse
- Allergies to drugs
- Allergies to food
- Allergies: general
- Amnesia
- Amputation and phantom limb pain
- Anaesthesia and psychology
- Antenatal care
- Aphasia recovery, treatment and psychosocial adjustment
- Asthma
- Back pain
- Blindness and visual disability
- Blood donation
- Breastfeeding
- Burn injuries: psychological and social aspects
- Cancer: breast
- Cancers of the digestive tract
- Cancer: general
- Cancer: gynaecologic
- Cancer: head and neck
- Cancer: Hodgkin's and non-Hodgkin's lymphoma
- Cancer: leukaemia
- Cancer: lung
- Cancer: prostate
- Cancer: skin
- Carotid artery disease and treatment
- Chemotherapy
- Child abuse and neglect
- Chromosomal abnormalities
- Chronic fatigue syndrome
- Chronic obstructive pulmonary disease (COPD): chronic bronchitis and emphysema
- Cleft lip and palate
- Cold, common
- Complementary medicine
- Contraception
- Coronary heart disease: impact
- Coronary heart disease: cardiac psychology
- Coronary heart disease: heart failure
- Coronary heart disease: rehabilitation
- Coronary heart disease: surgery
- Cystic fibrosis
- Acquired hearing loss
- Dementias
- Diabetes mellitus
- Domestic violence, intimate partner violence and wife battering
- Drug dependency: benzodiazepines
- Drug dependence: opiates and stimulants
- Drugs: beta-blockers
- Drugs: psychotropic medication
- Dyslexia
- Eating disorders
- Eczema
- Endocrine disorders
- Enuresis
- Epilepsy
- Epstein–Barr virus infection
- Facial disfigurement and dysmorphology
- Fetal wellbeing: monitoring and assessment
- Gastric and duodenal ulcers
- Growth retardation
- Haemophilia
- Head injury
- Headache and migraine
- Herpes
- HIV/AIDS
- Hormone replacement therapy
- Hospital acquired infection
- Huntington's disease
- Hyperactivity
- Hypertension
- Hyperthyroidism
- Hyperventilation
- Hysterectomy
- Immunization
- Incontinence
- Infertility
- Inflammatory bowel disease
- Intensive care unit
- Intimate examinations
- Irritable bowel syndrome
- Lymphoedema
- Malaria
- Mastalgia (breast pain)
- Meningitis
- Menopause and postmenopause
- MMR vaccine
- Motor neurone disease
- Multiple sclerosis
- Myasthenia gravis
- Neurofibromatosis
- Non-cardiac chest pain
- Obesity
- Oral care and hygiene
- Osteoarthritis
- Osteoporosis
- Parkinson's disease
- Pelvic pain
- Post-traumatic stress disorder
- Postnatal depression
- Pregnancy and childbirth
- Premature babies
- Premenstrual syndrome
- Psoriasis
- Radiotherapy
- Rape and sexual assault
- Reconstructive and cosmetic surgery
- Renal failure, dialysis and transplantation
- Repetitive strain injury
- Rheumatoid arthritis
- Road traffic accidents: human factors
- Screening: antenatal
- Screening: cancer
- Screening: cardiac
- Screening: genetic
- Self-examination: breasts, testicles
- Sexual dysfunction
- Sexually transmitted infections
- Sickle cell disease
- Skin disorders
- Sleep apnoea
- Sleep disorders
- Spina bifida
- Spinal cord injury
- Sterilization and vasectomy
- Stroke
- Stuttering
- Suicide
- Tinnitus
- Tobacco use
- Toxins: environmental
- Transplantation
- Urinary tract symptoms
- Vertigo and dizziness
- Vision disorders
- Voice disorders
- Volatile substance abuse
- Vomiting and nausea
- Index
- References
Haemophilia
from Medical topics
Published online by Cambridge University Press: 18 December 2014
- Frontmatter
- Contents
- List of contributors
- Preface
- Psychology, health and illness
- Medical topics
- Abortion
- Accidents and unintentional injuries
- Acne
- Alcohol abuse
- Allergies to drugs
- Allergies to food
- Allergies: general
- Amnesia
- Amputation and phantom limb pain
- Anaesthesia and psychology
- Antenatal care
- Aphasia recovery, treatment and psychosocial adjustment
- Asthma
- Back pain
- Blindness and visual disability
- Blood donation
- Breastfeeding
- Burn injuries: psychological and social aspects
- Cancer: breast
- Cancers of the digestive tract
- Cancer: general
- Cancer: gynaecologic
- Cancer: head and neck
- Cancer: Hodgkin's and non-Hodgkin's lymphoma
- Cancer: leukaemia
- Cancer: lung
- Cancer: prostate
- Cancer: skin
- Carotid artery disease and treatment
- Chemotherapy
- Child abuse and neglect
- Chromosomal abnormalities
- Chronic fatigue syndrome
- Chronic obstructive pulmonary disease (COPD): chronic bronchitis and emphysema
- Cleft lip and palate
- Cold, common
- Complementary medicine
- Contraception
- Coronary heart disease: impact
- Coronary heart disease: cardiac psychology
- Coronary heart disease: heart failure
- Coronary heart disease: rehabilitation
- Coronary heart disease: surgery
- Cystic fibrosis
- Acquired hearing loss
- Dementias
- Diabetes mellitus
- Domestic violence, intimate partner violence and wife battering
- Drug dependency: benzodiazepines
- Drug dependence: opiates and stimulants
- Drugs: beta-blockers
- Drugs: psychotropic medication
- Dyslexia
- Eating disorders
- Eczema
- Endocrine disorders
- Enuresis
- Epilepsy
- Epstein–Barr virus infection
- Facial disfigurement and dysmorphology
- Fetal wellbeing: monitoring and assessment
- Gastric and duodenal ulcers
- Growth retardation
- Haemophilia
- Head injury
- Headache and migraine
- Herpes
- HIV/AIDS
- Hormone replacement therapy
- Hospital acquired infection
- Huntington's disease
- Hyperactivity
- Hypertension
- Hyperthyroidism
- Hyperventilation
- Hysterectomy
- Immunization
- Incontinence
- Infertility
- Inflammatory bowel disease
- Intensive care unit
- Intimate examinations
- Irritable bowel syndrome
- Lymphoedema
- Malaria
- Mastalgia (breast pain)
- Meningitis
- Menopause and postmenopause
- MMR vaccine
- Motor neurone disease
- Multiple sclerosis
- Myasthenia gravis
- Neurofibromatosis
- Non-cardiac chest pain
- Obesity
- Oral care and hygiene
- Osteoarthritis
- Osteoporosis
- Parkinson's disease
- Pelvic pain
- Post-traumatic stress disorder
- Postnatal depression
- Pregnancy and childbirth
- Premature babies
- Premenstrual syndrome
- Psoriasis
- Radiotherapy
- Rape and sexual assault
- Reconstructive and cosmetic surgery
- Renal failure, dialysis and transplantation
- Repetitive strain injury
- Rheumatoid arthritis
- Road traffic accidents: human factors
- Screening: antenatal
- Screening: cancer
- Screening: cardiac
- Screening: genetic
- Self-examination: breasts, testicles
- Sexual dysfunction
- Sexually transmitted infections
- Sickle cell disease
- Skin disorders
- Sleep apnoea
- Sleep disorders
- Spina bifida
- Spinal cord injury
- Sterilization and vasectomy
- Stroke
- Stuttering
- Suicide
- Tinnitus
- Tobacco use
- Toxins: environmental
- Transplantation
- Urinary tract symptoms
- Vertigo and dizziness
- Vision disorders
- Voice disorders
- Volatile substance abuse
- Vomiting and nausea
- Index
- References
Summary
‘Haemophilia’ is a term referring to a group of genetically transmitted life-long blood clotting disorders which are caused by a defect in one or more of the plasma clotting factors. The most common are sex-linked recessive disorders, haemophilia A (classic haemophilia) and haemophilia B (Christmas disease), which are due to an isolated deficiency of the clotting activity of factor VIII or of factor IX, respectively. People with these disorders suffer bleeding into soft tissues, for example, joints, muscles or internal organs, which can happen after trauma or spontaneously. These bleeds can be very painful, and repeated episodes lead to weakening and crippling of joints. Bleeds into internal organs and the brain can be life-threatening. There is no cure for haemophilia.
Another common blood disorder is von Willebrand's disease or vascular haemophilia. It is an autosomal dominant genetic disorder, i.e. it is not sex-linked and affects both men and women. It is due to a combination of an abnormal factor VIII molecule with abnormal platelet function. Many problems related to treatment and its complications, as well as social and psychological problems are similar to those found in haemophilia A and B.
Genetics and clinical manifestation
Haemophilias A and B are genetically transmitted as follows: an affected woman carries a defective gene on one of her X chromosomes, which she can pass to any of her children.
- Type
- Chapter
- Information
- Cambridge Handbook of Psychology, Health and Medicine , pp. 718 - 720Publisher: Cambridge University PressPrint publication year: 2007
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