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Toxins: environmental

from Medical topics

Published online by Cambridge University Press:  18 December 2014

Gerhard Winneke
Affiliation:
Heinrich-Heine-Universität Düsseldorf
Susan Ayers
Affiliation:
University of Sussex
Andrew Baum
Affiliation:
University of Pittsburgh
Chris McManus
Affiliation:
St Mary's Hospital Medical School
Stanton Newman
Affiliation:
University College and Middlesex School of Medicine
Kenneth Wallston
Affiliation:
Vanderbilt University School of Nursing
John Weinman
Affiliation:
United Medical and Dental Schools of Guy's and St Thomas's
Robert West
Affiliation:
St George's Hospital Medical School, University of London
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Summary

Psychology and environmental toxicology

Environmental toxins that affect human health and wellbeing may either be airborne or foodborne. The primary target of airborne environmental toxins are the upper and lower airways, and various respiratory diseases have been shown to be related to environmental exposure to air pollution. However, if a toxin enters the deeper structures of the lung due to small molecular size, inhaled chemicals will also enter the blood stream, thus causing or contributing to damage of other organ systems, such as the cardiovascular system, the immune system, the endocrine system or the brain. If primarily foodborne, environmental toxins will be ingested rather than inhaled. The distinction between airborne and foodborne is somewhat artificial because airborne chemicals are often deposited on soil and water and may, thus, enter the food chain.

Since many organs and organ systems can be targets of environmental toxins, different scientific approaches and sharing of knowledge across disciplines are required in order to arrive at a balanced rational risk assessment. If the brain is assumed or known to be the critical organ for a particular toxin, its adverse effect at a particular level of environmental exposure is typically studied within neurotoxicology. General neurotoxicology draws upon a broad spectrum of general neuroscience methods, such as neuroanatomy, neurochemistry, neurophysiology or neuropharmacology to study adverse effects of chemicals on the structure and function of the mature or developing nervous system.

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Publisher: Cambridge University Press
Print publication year: 2007

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References

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