Book contents
- Frontmatter
- Contents
- List of contributors
- Preface
- Psychology, health and illness
- Medical topics
- Abortion
- Accidents and unintentional injuries
- Acne
- Alcohol abuse
- Allergies to drugs
- Allergies to food
- Allergies: general
- Amnesia
- Amputation and phantom limb pain
- Anaesthesia and psychology
- Antenatal care
- Aphasia recovery, treatment and psychosocial adjustment
- Asthma
- Back pain
- Blindness and visual disability
- Blood donation
- Breastfeeding
- Burn injuries: psychological and social aspects
- Cancer: breast
- Cancers of the digestive tract
- Cancer: general
- Cancer: gynaecologic
- Cancer: head and neck
- Cancer: Hodgkin's and non-Hodgkin's lymphoma
- Cancer: leukaemia
- Cancer: lung
- Cancer: prostate
- Cancer: skin
- Carotid artery disease and treatment
- Chemotherapy
- Child abuse and neglect
- Chromosomal abnormalities
- Chronic fatigue syndrome
- Chronic obstructive pulmonary disease (COPD): chronic bronchitis and emphysema
- Cleft lip and palate
- Cold, common
- Complementary medicine
- Contraception
- Coronary heart disease: impact
- Coronary heart disease: cardiac psychology
- Coronary heart disease: heart failure
- Coronary heart disease: rehabilitation
- Coronary heart disease: surgery
- Cystic fibrosis
- Acquired hearing loss
- Dementias
- Diabetes mellitus
- Domestic violence, intimate partner violence and wife battering
- Drug dependency: benzodiazepines
- Drug dependence: opiates and stimulants
- Drugs: beta-blockers
- Drugs: psychotropic medication
- Dyslexia
- Eating disorders
- Eczema
- Endocrine disorders
- Enuresis
- Epilepsy
- Epstein–Barr virus infection
- Facial disfigurement and dysmorphology
- Fetal wellbeing: monitoring and assessment
- Gastric and duodenal ulcers
- Growth retardation
- Haemophilia
- Head injury
- Headache and migraine
- Herpes
- HIV/AIDS
- Hormone replacement therapy
- Hospital acquired infection
- Huntington's disease
- Hyperactivity
- Hypertension
- Hyperthyroidism
- Hyperventilation
- Hysterectomy
- Immunization
- Incontinence
- Infertility
- Inflammatory bowel disease
- Intensive care unit
- Intimate examinations
- Irritable bowel syndrome
- Lymphoedema
- Malaria
- Mastalgia (breast pain)
- Meningitis
- Menopause and postmenopause
- MMR vaccine
- Motor neurone disease
- Multiple sclerosis
- Myasthenia gravis
- Neurofibromatosis
- Non-cardiac chest pain
- Obesity
- Oral care and hygiene
- Osteoarthritis
- Osteoporosis
- Parkinson's disease
- Pelvic pain
- Post-traumatic stress disorder
- Postnatal depression
- Pregnancy and childbirth
- Premature babies
- Premenstrual syndrome
- Psoriasis
- Radiotherapy
- Rape and sexual assault
- Reconstructive and cosmetic surgery
- Renal failure, dialysis and transplantation
- Repetitive strain injury
- Rheumatoid arthritis
- Road traffic accidents: human factors
- Screening: antenatal
- Screening: cancer
- Screening: cardiac
- Screening: genetic
- Self-examination: breasts, testicles
- Sexual dysfunction
- Sexually transmitted infections
- Sickle cell disease
- Skin disorders
- Sleep apnoea
- Sleep disorders
- Spina bifida
- Spinal cord injury
- Sterilization and vasectomy
- Stroke
- Stuttering
- Suicide
- Tinnitus
- Tobacco use
- Toxins: environmental
- Transplantation
- Urinary tract symptoms
- Vertigo and dizziness
- Vision disorders
- Voice disorders
- Volatile substance abuse
- Vomiting and nausea
- Index
- References
Huntington's disease
from Medical topics
Published online by Cambridge University Press: 18 December 2014
- Frontmatter
- Contents
- List of contributors
- Preface
- Psychology, health and illness
- Medical topics
- Abortion
- Accidents and unintentional injuries
- Acne
- Alcohol abuse
- Allergies to drugs
- Allergies to food
- Allergies: general
- Amnesia
- Amputation and phantom limb pain
- Anaesthesia and psychology
- Antenatal care
- Aphasia recovery, treatment and psychosocial adjustment
- Asthma
- Back pain
- Blindness and visual disability
- Blood donation
- Breastfeeding
- Burn injuries: psychological and social aspects
- Cancer: breast
- Cancers of the digestive tract
- Cancer: general
- Cancer: gynaecologic
- Cancer: head and neck
- Cancer: Hodgkin's and non-Hodgkin's lymphoma
- Cancer: leukaemia
- Cancer: lung
- Cancer: prostate
- Cancer: skin
- Carotid artery disease and treatment
- Chemotherapy
- Child abuse and neglect
- Chromosomal abnormalities
- Chronic fatigue syndrome
- Chronic obstructive pulmonary disease (COPD): chronic bronchitis and emphysema
- Cleft lip and palate
- Cold, common
- Complementary medicine
- Contraception
- Coronary heart disease: impact
- Coronary heart disease: cardiac psychology
- Coronary heart disease: heart failure
- Coronary heart disease: rehabilitation
- Coronary heart disease: surgery
- Cystic fibrosis
- Acquired hearing loss
- Dementias
- Diabetes mellitus
- Domestic violence, intimate partner violence and wife battering
- Drug dependency: benzodiazepines
- Drug dependence: opiates and stimulants
- Drugs: beta-blockers
- Drugs: psychotropic medication
- Dyslexia
- Eating disorders
- Eczema
- Endocrine disorders
- Enuresis
- Epilepsy
- Epstein–Barr virus infection
- Facial disfigurement and dysmorphology
- Fetal wellbeing: monitoring and assessment
- Gastric and duodenal ulcers
- Growth retardation
- Haemophilia
- Head injury
- Headache and migraine
- Herpes
- HIV/AIDS
- Hormone replacement therapy
- Hospital acquired infection
- Huntington's disease
- Hyperactivity
- Hypertension
- Hyperthyroidism
- Hyperventilation
- Hysterectomy
- Immunization
- Incontinence
- Infertility
- Inflammatory bowel disease
- Intensive care unit
- Intimate examinations
- Irritable bowel syndrome
- Lymphoedema
- Malaria
- Mastalgia (breast pain)
- Meningitis
- Menopause and postmenopause
- MMR vaccine
- Motor neurone disease
- Multiple sclerosis
- Myasthenia gravis
- Neurofibromatosis
- Non-cardiac chest pain
- Obesity
- Oral care and hygiene
- Osteoarthritis
- Osteoporosis
- Parkinson's disease
- Pelvic pain
- Post-traumatic stress disorder
- Postnatal depression
- Pregnancy and childbirth
- Premature babies
- Premenstrual syndrome
- Psoriasis
- Radiotherapy
- Rape and sexual assault
- Reconstructive and cosmetic surgery
- Renal failure, dialysis and transplantation
- Repetitive strain injury
- Rheumatoid arthritis
- Road traffic accidents: human factors
- Screening: antenatal
- Screening: cancer
- Screening: cardiac
- Screening: genetic
- Self-examination: breasts, testicles
- Sexual dysfunction
- Sexually transmitted infections
- Sickle cell disease
- Skin disorders
- Sleep apnoea
- Sleep disorders
- Spina bifida
- Spinal cord injury
- Sterilization and vasectomy
- Stroke
- Stuttering
- Suicide
- Tinnitus
- Tobacco use
- Toxins: environmental
- Transplantation
- Urinary tract symptoms
- Vertigo and dizziness
- Vision disorders
- Voice disorders
- Volatile substance abuse
- Vomiting and nausea
- Index
- References
Summary
Huntington's disease (HD) is a genetic disease which is transmitted as an autosomal dominant trait. It is a chronic degenerative disease of the CNS characterized by movement disorder, cognitive deterioration and personality change. While found in all parts of the world HD is most commonly found in Caucasians of whom about 1:10 000 individuals are affected. Onset is subtle and insidious and occurs most frequently between 30 and 50 years of age. Juvenile onset is seen in about 10% of cases and about 20% have onset at over 50 years of age with diagnoses as late as the eighth decade reported. The disease progresses inexorably, culminating in death usually 15 to 25 years after observed onset. Late onset HD tends to progress more slowly than early onset forms of the disease. There is thus far no effective treatment or cure for the disease.
HD is commonly known for its jerky, dance-like (choreic) movements. Movement may, however, also be rigid, especially in the juvenile form and the later stages of the adult form. Cognitive deficits (dementia) commonly associated with HD include difficulty with memory (primarily a retrieval problem), attention and concentration. While the dementia of HD is primarily subcortical and is non-aphasic, it includes many additional cognitive functions such as cognitive speed and fluency verbal fluency, difficulty persisting with, or initiating, a task and with change of set (see also ‘Dementias’).
Becoming affected with HD may have a tremendous impact on the psyche. Organic change is compounded with psychological trauma.
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- Chapter
- Information
- Cambridge Handbook of Psychology, Health and Medicine , pp. 738 - 740Publisher: Cambridge University PressPrint publication year: 2007