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In Harry Frankfurt’s seminal “Alternate Possibilities and Moral Responsibility,” he advances an argument against the Principle of Alternate Possibilities: if an agent is responsible for performing some action, then she is able to do otherwise. However, almost all of the Frankfurt cases in this literature involve impermissible actions. In this article, I argue that the failure to consider other deontic categories exposes a deep problem, one that threatens either to upend much current moral theorizing or to upend the relevance of Frankfurt cases.
Adaptation to intimate partner violence (IPV) exposure involves alterations in transdiagnostic processes including effortful control (EC), and yet little attention has been given to the ways such processes interact with family-level factors, such as caregivers’ psychopathology. This study used latent change score modeling to compare trajectories of EC and caregivers’ depressive (CD) symptoms between children and adolescents (N = 365) ages 7–17 who had witnessed IPV (IPV+; 45.3%) and those who had not (IPV−) across 3 years. Findings suggested that IPV exposure moderated relationships between EC and CD. CD was higher and EC was lower for IPV+ relative to IPV− participants, although there was significant variation around mean-level CD and EC in both groups. CD and EC were only linked for IPV+ participants, where higher baseline CD was associated with lower EC that lagged behind IPV− participants’ EC across the 3 years of the study. Rates of change for CD significantly varied for the IPV+ group only, indicating that individual difference factors interacted with IPV exposure to influence changes in CD. These findings inform literature on transdiagnostic adaptation processes and point to the potential utility of interventions to reduce IPV and CD in supporting EC in children and adolescents across contexts.
We study a family of finitely generated residually finite small-cancellation groups. These groups are quotients of $F_2$ depending on a subset $S$ of positive integers. Varying $S$ yields continuously many groups up to quasi-isometry.
Repetitive transcranial magnetic stimulation (rTMS) is used for treatment of late-life depression. In the FOUR-D study, sequential bilateral theta-burst stimulation (TBS) had comparable remission rates to standard bilateral rTMS. Data were analysed from the FOUR-D trial to compare remission rates between two types of rTMS based on the number and class of prior medication trials. The remission rate was higher in participants with ≤1 previous trial (43.9%) than in participants with 2 previous trials (26.5%) or ≥3 previous trials (24.6%; χ² = 6.36, d.f. = 2, P = 0.04). Utilising rTMS earlier in late-life depression may lead to better outcomes.
Recent geopolitical and environmental events have created a new urgency for a just energy transition and a socially inclusive modernization of the energy sector. This article critically evaluates the extent to which Article 194(1) of the Treaty on the Functioning of the European Union (TFEU), as the competence provision of EU energy law, is congruent with the energy justice framework emerging from social sciences. It establishes the substantive scope and justiciability of Article 194(1) TFEU, including the legal principles and so-called ‘guiding principles’ of the provision relating to the internal market, environmental protection, and energy solidarity. The article analyzes the potential and shortcomings of Article 194(1) TFEU in contributing to more equitable decision-making processes in EU energy law. It concludes by evaluating the provision as a regulatory instrument that facilitates the (re)balancing of competing interests of the energy sector. This research further concludes that social considerations of energy justice cannot be sufficiently addressed through Article 194(1) TFEU.
This paper revisits the 1995 IALC Dublin Statement on the Eucharist, focusing on the Eucharistic Prayer. It reviews newer insights and studies on the Eucharistic Prayer, and suggests how that broadly may impact subsequent Anglican use of ‘classical patterns’, It also puts forward suggestions and questions posed by some more recent Anglican revisions as well as revisiting some areas of the Dublin Statement that are still useul or so far have not been fully embraced in Anglican liturgical revision.
We define and study properties of implied volatility for American perpetual put options. In particular, we show that if the market prices are derived from a local volatility model with a monotone volatility function, then the corresponding implied volatility is also monotone as a function of the strike price.
This study used the European Laryngeal Society (2016) and Ni (2011 and 2019) classifications for narrow-band imaging and correlated the findings with histopathology.
Methods
Retrospective analysis was conducted by retrieving data of patients who underwent micro-laryngoscopy for suspicious glottic lesions. The narrow-band imaging findings were classified using both classification systems. Retrieved histopathology report findings were correlated with narrow-band imaging data.
Results
Using the European Laryngeal Society and Ni classifications, 37 (69.8 per cent) and 35 (66 per cent) patients, respectively, were suspected to have malignant lesions. Upon histopathology, 37 (69.8 per cent) lesions were malignant. Sensitivity, specificity, positive predictive value, negative predictive value and accuracy using the European Laryngeal Society classification were 91.9 per cent, 81.3 per cent, 91.9 per cent, 81.3 per cent and 88.7 per cent, and using the Ni classification were 91.9 per cent, 93.8 per cent, 97.1 per cent, 83.3 per cent and 92.5 per cent, respectively.
Conclusion
The Ni classification had better specificity and accuracy. The European Laryngeal Society classification is simple to use and may serve as a useful screening tool. For optimum results, both European Laryngeal Society and Ni classifications may be used together, in that order.
Pragmatism gained considerable attention in bioethical discussions in the early 21st century. However, some dimensions and contributions of pragmatism to bioethics remain underexplored in both research and practice. It is argued that pragmatism can make a distinctive contribution to bioethics through its concept, developed by Charles S. Peirce and John Dewey, that ethical issues can be resolved through experimental inquiry. Dewey’s proposal that policies can be confirmed or disconfirmed through experimentation is developed by comparing it to the confirmation of scientific hypotheses, with a focus on the objection that the consequences of following a moral view or policy do not provide guidance on choosing among competing ethical perspectives. As confirmation of scientific hypotheses typically relies on evidence gathered from observation, the possibility of ethically relevant observation is then explored based on Peirce’s views on feelings as emotional interpretants. Finally, the connection between Dewey’s experimental ethics and democracy is outlined and compared to unfettered ethical progressivism.
When a party selects an out lesbian as its leader, do women and LGBT people evaluate that leader more positively? And do they become more likely to vote for that party? We answer these questions using the case of Kathleen Wynne, premier of Ontario, Canada, from 2013 to 2018. We draw on four large-sample surveys conducted by Ipsos before and after the 2011 and 2014 Ontario elections. We compare shifts in best premier choice and vote choice among non-LGBT men, non-LGBT women, LGBT men, and LGBT women from 2011 to 2014. We find gender and LGBT affinity in leader evaluations. However, we find that only non-LGBT women and LGBT men were more likely to vote Liberal after Wynne became leader. This article contributes to research on affinity by examining LGBT affinity in a real-world election and the intersection of gender and LGBT affinity.
This study examines the racialized and gendered experiences of Black men (N = 20) from elementary school through graduate school. The Black men featured in this article are current STEM doctoral students and were asked to reflect on their K-12 and undergraduate STEM experiences as well as their current experiences as graduate students. Findings conclude that Black men, as children and teens, experienced gendered racism in their STEM courses, which included a severe lack of racial representation of Black scientists, leading them to believe that they could not become scientists in their respective disciplines. At the undergraduate level, Black men encountered racial stereotyping and were self-conscious of their gender and race due to being underrepresented in their STEM courses. And at the doctoral level, Black men deal with psychological health issues due to the racism-related stressors they experience on campus, along with feeling compelled to be the spokesperson for Black students at their respective college campuses.
Let G be a graph with no isolated vertex. A semitotal forcing set of G is a (zero) forcing set S such that every vertex in S is within distance 2 of another vertex of S. The semitotal forcing number $F_{t2}(G)$ is the minimum cardinality of a semitotal forcing set in G. In this paper, we prove that it is NP-complete to determine the semitotal forcing number of a graph. We also prove that if $G\neq K_n$ is a connected graph of order $n\geq 4$ with maximum degree $\Delta \geq 2$, then $F_{t2}(G)\leq (\Delta-1)n/\Delta$, with equality if and only if either $G=C_{4}$ or $G=P_{4}$ or $G=K_{\Delta ,\Delta }$.
To assess the impact of a 24-hour autocancellation of uncollected Clostridioides difficile samples in reducing reported healthcare-associated infections (HAIs).
The study was conducted in 17 hospitals in Pennsylvania.
Interventions:
Clostridioides difficile tests that are not collected within 24 hours are automatically canceled (“autocancel”) through the electronic health record. The intervention took place at 2 facilities (intervention period November 2021–July 2022) and subsequently at 15 additional facilities (April 2022–July 2022). Quality measures included percentage of orders canceled, C. difficile HAI rate, percent positivity of completed tests, and potential adverse outcomes of canceled or delayed testing.
Results:
Of 6,101 orders, 1,090 (17.9%) were automatically canceled after not being collected for 24 hours during the intervention periods. The reported C. difficile HAI rates per 10,000 patient days did not significantly change. These rates were 8.07 in the 6-month preintervention period and 8.77 in the intervention period for facilities A and B combined (incidence rate ratio [IRR], 1.09; 95% CI, 0.88–1.34; P = .43), and were 5.23 HAIs per 10,000 patient days in the 6-month preintervention period and 5.33 in the intervention period for facilities C–Q combined (IRR, 1.02; 95% CI, 0.79–1.32; P = .87). From the preintervention to the intervention periods, the percent positivity rates of completed C. difficile tests increased by 1.1% for facilities A and B and by 1.4% for facilities C–Q. No adverse outcomes were observed.
Conclusions:
The 24-hour autocancellation of uncollected C. difficile orders reduced testing but did not result in reported HAI reduction.