Globally, gender equality is the next frontier for social transformation, and women’s economic empowerment is promoted as the pathway to achieve this goal, particularly in countries of the Global South. Women’s economic empowerment is broadly defined as women’s capacity to contribute to, and benefit from, economic activities on terms that recognise the value of their contributions. Advocates for women’s economic empowerment state that it has the potential to be a safeguard against poverty and precarity by enhancing women’s wellbeing. Using a critical-feminist lens, we explore the benefits and risks of the global trend towards women’s economic empowerment. After providing an overview of the evolution of the concept of empowerment, we review the benefits of women’s economic empowerment: economic growth, improved rates of tertiary education and market participation for women, and growth of women’s autonomy. We then examine the risks of the global focus on women’s economic empowerment, which we distil into three key areas: (a) women seen as a country’s ‘natural resource’, used as instruments for economic prosperity and reproduction without considering their wellbeing; (b) a focus on women’s market participation without adequately factoring in current labour market realities; and (c) pushing the women’s economic empowerment agenda forward without fully considering the scope of unpaid reproductive work undertaken by women. We conclude with an analysis of how UN Women (2024) is shifting the agenda by providing a holistic framework for thinking about women’s economic empowerment. We suggest that there is room for cautious optimism if this framework is widely adopted.

The Cold War is often depicted in binary terms: communists against anti-communists, the left against the right, or the free world versus the communist world. However, during the latter part of the Cold War, particularly following the 1979 war between China and Vietnam, earlier Cold War binaries no longer applied, and new alliances were established. These alliances often brought people with the same enemies together, despite having little in common ideologically. This article examines the historical circumstances and Cold War geographies of ethnic Khmu anti-Lao PDR and anti-Vietnamese insurgents, including their alliances with right-wing governments in Thailand and the communist People’s Republic of China (PRC). As neutralists, these Khmu occupied a political space rarely discussed in relation to the Cold War. Although the PRC provided training, weapons, and supplies to the neutralist Khmu between 1979 and 1983, later their political leader, General Kong Le, had a falling out with the Chinese, and the PRC stopped supporting his largely ethnic minority soldiers. However, up until 1989, the Thai government continued to allow the Khmu to maintain bases in Thailand for launching military operations inside Laos, until the Thai government adopted the “Battlefield to Marketplace” policy. Some Khmu continued resisting inside northwestern Laos during the early 1990s, but with declining numbers of soldiers and decreased outside support, armed resistance ended in 2003. It is critical that the geographies and alliances of the later Cold War be differentiated from those of the earlier years of the Cold War. This transnational insurgency deserves attention.

The Mazon Creek Lagerstätte (Moscovian Stage, late Carboniferous Period; Illinois, USA) captures a diverse view of ecosystems in delta-influenced coastal settings through exceptional preservation of soft tissues in siderite concretions. The generally accepted paradigm of the Mazon Creek biota has been that of an inferred paleoenvironmental divide between what have been termed the Braidwood and Essex assemblages, wherein the former represents a freshwater ecosystem with terrestrial input and the latter a marine-influenced prodelta setting with abundant cnidarians, bivalves, worm phyla, and diverse arthropods. Here, we revisit the paleoecology of the Mazon Creek biota by analyzing data from nearly 300,000 concretions from more than 270 locations with complementary multivariate ordinations. Our results show the Braidwood assemblage as a legitimate shoreward community and provide evidence for further subdivision of the Essex assemblage into two distinct subassemblages, termed here the Will-Essex and Kankakee-Essex. The Will-Essex represents a benthos dominated by clams and trace fossils along the transition between nearshore and offshore deposits. The Kankakee-Essex is dominated by cnidarians, presenting an ecosystem approaching the geographic margin of this taphonomic window. These new insights also allow a refined taphonomic model, wherein recalcitrant tissues of Braidwood organisms were subject to rapid burial rates, while organisms of the Essex assemblage typically had more labile tissues and were subject to slower burial rates. Consequently, we hypothesize that the Braidwood fossils should record more complete preservation than the Essex, which was exposed for longer periods of aerobic decomposition. This is supported by a higher proportion of non-fossiliferous concretions in the Essex than in the Braidwood.

Multicenter clinical trials are essential for evaluating interventions but often face significant challenges in study design, site coordination, participant recruitment, and regulatory compliance. To address these issues, the National Institutes of Health’s National Center for Advancing Translational Sciences established the Trial Innovation Network (TIN). The TIN offers a scientific consultation process, providing access to clinical trial and disease experts who provide input and recommendations throughout the trial’s duration, at no cost to investigators. This approach aims to improve trial design, accelerate implementation, foster interdisciplinary teamwork, and spur innovations that enhance multicenter trial quality and efficiency. The TIN leverages resources of the Clinical and Translational Science Awards (CTSA) program, complementing local capabilities at the investigator’s institution. The Initial Consultation process focuses on the study’s scientific premise, design, site development, recruitment and retention strategies, funding feasibility, and other support areas. As of 6/1/2024, the TIN has provided 431 Initial Consultations to increase efficiency and accelerate trial implementation by delivering customized support and tailored recommendations. Across a range of clinical trials, the TIN has developed standardized, streamlined, and adaptable processes. We describe these processes, provide operational metrics, and include a set of lessons learned for consideration by other trial support and innovation networks.

Assessing children’s diets is currently challenging and burdensome. Abbreviated FFQ have the potential to assess dietary patterns in a rapid and standardised manner. Using nationally representative UK dietary intake and biomarker data, we developed an abbreviated FFQ to calculate dietary quality scores for pre-school and primary school-aged children. UK National Diet and Nutrition Survey (2008–2016) weekly consumption frequencies of 129 food groups from 4-d diaries were cross-sectionally analysed using principal component analysis. A 129-item score was derived, alongside a 12-item score based on foods with the six highest and six lowest coefficients. Participants included 1069 pre-schoolers and 2565 primary schoolchildren. The first principal component explained 3·4 and 3·0 % of the variation in the original diet variables for pre-school and primary school groups, respectively, and described a prudent diet pattern. Prudent diet scores were characterised by greater consumption of fruit, vegetables and tap water and lower consumption of crisps, manufactured coated chicken/turkey products, purchased chips and soft drinks for both age groups. Correlations between the 129-item and 12-item scores were 0·86 and 0·84 for pre-school and primary school-aged children, respectively. Bland–Altman mean differences between the scores were 0·00 sd; 95 % limits of agreement were −1·05 to 1·05 and −1·10 to 1·10 sd for pre-school and primary school-aged children, respectively. Correlations between dietary scores and nutritional biomarkers showed only minor attenuation for the 12-item compared with the 129-item scores, illustrating acceptable congruence between prudent diet scores. The two 12-item FFQ offer user-friendly tools to measure dietary quality among UK children.

Despite its relative invisibility to most people living in the urban Asia-Pacific, endemic malaria occurs across the region. The unique character of Asian-Pacific malaria includes a serious problem of drug resistance, dominance of a particularly difficult species to control and treat, and another that normally dwells in monkeys but often infects humans. Most nations in the region with endemic malaria have called for its elimination by the year 2030. Meeting that ambitious goal will require mobilizing technical and financial resources, and social and political will. Malaria is a formidable foe fully capable of defeating halfhearted efforts to eliminate it.

On July 3, 1945 the Japanese occupation government of the East Indies executed by sword the prominent Professor Achmad Mochtar. Until his arrest by the Kenpeitai in October 1944 he directed the Eijkman Institute in Jakarta, a prestigious Nobel Prize-winning medical research laboratory. Mochtar was not only an internationally known scientist physician, but he was also closely connected to powerful Indonesian nationalist elites. The complex swirl of violent military and political currents, together with the complex technical elements of the events impelling Mochtar's execution, composes what the scholar of Indonesian history Theodore Friend referred to as “the Mochtar affair”. The defining event of this affair was the murder of 900 conscripted Javanese laborers (called romusha, a Japanese word meaning unskilled laborer but adopted in Indonesian language to mean slave laborer) at a transit camp on the outskirts of Jakarta in August 1944. They all died of acute tetanus within three days of receiving vaccinations against typhus, cholera and dysentery.

Transnational marriage is a controversial topic in Hmong communities in the United States, Laos, and Thailand, and has sometimes led to intra-ethnic disputes and conflicts. Initially, many of the Hmong American men who travelled overseas to marry Hmong Lao or Thai women were already married. Furthermore, the Hmong American community has frequently come to believe that economic gain is the primary motivation for Hmong Lao/Thai women to marry Hmong American men. On the other hand, some activists have referred to these marriages generally as “abusive transnational marriages.” The association of economic resources with transnational marriage, including remittances, increased bride prices, and opportunities for migration to the United States, has perpetuated negative stereotypes that frequently overshadow the personal stories of many Hmong Lao/Thai women who do not fit with the stereotypes. For these women, marrying a Hmong American man signifies not only personal gain but also economic advancement for their families. This paper reviews the intricacies related to the topic of Hmong transnational marriage between Hmong American men and their Hmong Lao and Hmong Thai brides. In doing so, we argue that it is important to consider the complexity and nuances associated with Hmong transnational marriages, as they take on various forms that go beyond standard stereotypes.

During the Third Indochina War (1979-1991), the ideological alignments of involved parties differed from those during the Second Indochina War, also known as the Vietnam War. Whereas the Second Indochina War pitted communists squarely against non-communists and anti-communists, the Third Indochina War was more complicated and less ideological or political, with communists often fighting against other communists due to the Sino-Soviet ideological split. The enemy of one's enemy was frequently viewed as a friend, often leading to unlikely alliances not rooted in ideological or political similarities. In this article, I argue that it is important to consider the unlikely alliances that emerged during the Third Indochina War by focusing on the particular cross-border interactions and conflicts between communists and non-communists that occurred in the Emerald Triangle, the tri-border region between Laos, Cambodia and Thailand. Focusing particularly on the Lao insurgent perspective, I consider how Lao anti-communist insurgents, the Khmer Rouge, the Communist Party of Thailand, other armed groups, and the Thai military participated in transnational collaboration in this region during the Third Indochina War. In particular, based largely on Lao-language interviews with key figures in the Lao insurgency conducted for over a decade, I examine how Lao insurgents interacted with Khmer Rouge to oppose a common enemy, communist Vietnam and their allies, the People's Republic of Kampuchea and the Lao People's Democratic Republic, and how the Thai military supported them, but only insofar as it enabled them to maintain control over security inside Thailand.

Background: The Colorado Department of Public Health and Environment (CDPHE) detected an increase in Klebsiella pneumoniae carbapenemase-producing carbapenem-resistant Enterobacterales (KPC-CRE) infections in October 2022. We investigated patient epidemiological links and isolate relatedness to characterize interfacility transmission of KPC-CRE in the Denver metro area and inform regional prevention strategies. Methods: We defined a case as polymerase chain reaction detection of KPC from clinical or screening specimens collected during January 2022 – January 2023. Cases were identified through statewide CRE surveillance and carbapenemase testing at the CDPHE laboratory and counted once within a 30-day period. Medical records were reviewed to identify healthcare facility admissions and patient facility overlap in the 12 months prior to sample collection. Whole genome sequencing (WGS) was performed for 34 patients with available KPC-CRE isolates using short- and long-read sequencing techniques. We performed multi-locus sequence typing, generated genome phylogenetic trees, and compared plasmid contig sequences to identify relatedness between KPC-CRE isolates. Clusters were defined as ≥2 genetically related isolates of the same organism or carbapenemase plasmid, from different patients. Results: We identified 48 cases (34 clinical and 14 screening) among 39 patients (figure). Patients had a mean age of 52 years (range 16-86) and median of three healthcare facility admissions (range 1-14). Twenty-eight patients (72%) were male. We identified 16 (41%) patients with epidemiological links to one acute care hospital (ACH), 11 (28.2%) patients to one long-term acute care hospital (LTACH), and four (10.2%) patients to each of two ventilator-capable skilled nursing facilities (vSNF). Five distinct clusters of KPC-CRE were identified by WGS among 23 patients (E. hormaechei, two distinct E. cloacae clusters, K. pneumoniae, and K. oxytoca) with linkages to ten healthcare facilities, including two vSNFs, two LTACHs, and six ACHs. Three distinct KPC genes were identified among the clusters: KPC-2, KPC-3, and KPC-4. Genomes assembled from long reads identified identical or similar KPC-gene-containing plasmids across different species or sequence types, suggesting horizontal gene transfer of KPC. Conclusions: Multiple KPC-CRE strains co-circulated and were associated with patient movement between acute and post-acute care settings. WGS allowed us to identify multi-facility clusters. Time and location of carbapenemase acquisition were challenging to determine for genetically related isolates when epidemiologic links could not be determined from medical records. This could be due to undetected cases. We notified healthcare facilities of their shared transmission risk and advocated for improved attention to infection control, carbapenemase screening, and communication upon patient transfer.

Background: During 2021–2023, an increase in Klebsiella pneumoniae carbapenemase producing Enterobacterales species (KPC-CRE) cases occurred among patients admitted to several overlapping healthcare facilities, prompting an investigation by the Colorado Department of Public Health and Environment (CDPHE). We applied social network analysis (SNA) to identify KPC-CRE networks and other multidrug-resistant organism (MDRO) transmission, created a tool for public health prevention planning and for facilities to examine their own patient transfer connectivity, and explored additional public health and emergency preparedness applications. Methods: A statewide patient transfer network was created using 2021–2022 Medicare beneficiary data. Sub-networks were isolated from the larger network to examine a cluster of facilities involved in a KPC-CRE outbreak, defined as ≥2 KPC-CRE cases related by whole genome sequencing (WGS). WGS was conducted at the CDPHE State Lab. Highly connected facilities were determined by patient transfers between at least two KPC-CRE testing facilities. Individual patient journeys were constructed using admissions and culture date. SNA was conducted in RStudio; visualizations, network metric calculations, and clustering analysis were conducted using Gephi and ArcGIS software. Results: SNA yielded 4,864 direct patient transfers between 326 healthcare facilities (220 skilled nursing facilities, 50 acute care hospitals, 32 critical access hospitals, six long term acute care hospitals, and 18 facilities not previously classified; Figure 1). WGS identified five separate KPC-CRE outbreaks among 14 patients during February 2022–January 2023; 14 patient specimens were collected at four testing facilities. We identified five highly connected facilities in addition to the four testing facilities. Patient journeys allowed us to identify possible locations of KPC-CRE transmission in four of the five outbreaks (Figure 2). CDPHE provided guidance to all involved facilities on admission screening, routine point prevalence surveys, and interfacility communication as part of an MDRO prevention plan. CDPHE then developed the transfer network into an interactive ArcGIS dashboard enabling facilities to examine their own patient transfer patterns. Conclusions: SNA enabled CDPHE to identify at-risk facilities for KPC-CRE transmission and create an interactive tool for facility and public health use. Future applications of patient transfer networks can include geographical grouping of facilities based on transfers to zone healthcare coalitions and conduct preparedness activities, and creating medical operations preparedness plans for emergencies or disasters.