This article analyses a complex period in Colombian history, from the electoral victory of the Liberal Party in 1930 to the end of the Frente Nacional (National Front) in 1974, from the perspective of constitutional politics and constitutional theory. During this period, Colombia transited from democracy to dictatorship (civilian and military) and back to democracy. We therefore divide the period according to changes in regime type and also to changes in the degree of institutional constraints on power. We show that, due to combinations of regime type and constraints on power, under the same Constitution of 1886 three different constitutionalisms ensued: abusive, window-dressing, and authoritarian constitutionalism. Our analysis on Colombia highlights the role of powerful actors, such as the armed forces and the Catholic Church, that breathed life back into key constitutional provisions when these served as focal points for coordinating their actions even under an authoritarian regime.

Among body measurements, body weight (BW) is one of the most important within the buffalo production system, due to its association with economic characteristics. In previous research, we have shown that body volume (BV) is an effective predictor of BW in lactating adult water buffalo. As there are no equations to predict BW through BV for growing dairy buffaloes (young animals), we hypothesized that equations should be developed to meet this need. BW, body length (BL) and heart girth (HG) data were collected in 160 growing dairy buffaloes raised in commercial farms in southern Mexico, with body volume (BV) then estimated from BL and HG. The ratio between BV and BW was determined by linear, quadratic and allometric equations. The goodness-of-fit of the regression models was evaluated using the Akaike information criterion (AIC), the Bayesian information criterion (BIC), the coefficient of determination (R2), the mean square error (MSE) and the root MSE (RMSE). After this, the k-folds cross-validation was performed to indicate a better fit. Our results showed that the growing dairy buffaloes presented a BW of 256.6 ± 96.82 kg and a BV of 155.3 ± 74.87 dm3. High and positive correlation were observed among all variables studied. All parameters (R2, MSE, RMSE, AIC and BIC) used to evaluate the regression equations showed that the quadratic regression model was more effective than the linear and allometric models for estimating BW using BV. The criteria for evaluating and validating models showed that the quadratic model presented a better predictive performance. Based on these findings, we conclude that body volume data to estimate body weight of growing dairy buffaloes were best fitted using the quadratic regression model.

During nematode surveys conducted to investigate the biodiversity of plant-parasitic nematodes in Mediterranean olive groves with different management strategies (organic and conventional), a nematode population of the genus Neothada was detected in southern Spain. Application of integrative taxonomical approaches clearly demonstrated that it is a new species described herein as Neothada olearum sp. nov., also representing the first report of the genus in Spain. The new species is amphimictic, characterised by a short body (563–774 μm); cuticle widely annulated (2.5–3.0 μm); total number of body annuli 214–226; 16 longitudinal ridges giving a tessellate body surface; stylet without distinct basal knobs (9.0–11.0 μm); and tail elongate-conoid, with tip bluntly rounded. The results of molecular analysis of D2-D3 28S rRNA, ITS rRNA, partial 18S rRNA, and cytochrome oxidase c subunit 1 (COI) gene sequences support for the new species status and clearly separated from N. major and other species within Neothada. Phylogenetic analyses of ribosomal and mitochondrial markers of this study suggested that Neothada is a monophyletic genus, clearly separated from Thada.

We derive new cases of conjectures of Rubin and of Burns–Kurihara–Sano concerning derivatives of Dirichlet L-series at $s = 0$ in p-elementary abelian extensions of number fields for arbitrary prime numbers p. In naturally arising examples of such extensions one therefore obtains annihilators of class groups from S-truncated Dirichlet L-series for ‘large-enough’ sets of places S.

Despite being the most prevalent personality disorder, borderline personality disorder remains a diagnosis with many unanswered questions, particularly concerning pharmacological management. Although many clinical practice guidelines suggest not prescribing medication unless there are significant clinical comorbidities, it is one of the psychiatric diagnoses with the highest rates of polypharmacy. This commentary on a BJPsych Advances article aims to raise clinical questions regarding the voids of knowledge and the appropriateness of medicating and, perhaps, overmedicating in this particular group.

Despite the increased awareness and action towards Equality, Diversity and Inclusion (EDI), the glaciological community still experiences and perpetuates examples of exclusionary and discriminatory behavior. We here discuss the challenges and visions from a group predominantly composed of early-career researchers from the 2023 edition of the Karthaus Summer School on Ice Sheets and Glaciers in the Climate System. This paper presents the results of an EDI-focused workshop that the 36 students and 12 lecturers who attended the summer school actively participated in. We identify common threads from participant responses and distill them into collective visions for the future of the glaciological research community, built on actionable steps toward change. In this paper, we address the following questions that guided the workshop: What do we see as current EDI challenges in the glaciology research community and which improvements would we like to see in the next fifty years? Contributions have been sorted into three main challenges we want and need to face: making glaciology (1) more accessible, (2) more equitable and (3) more responsible.

Objectives/Goals: Unhealthy lifestyle habits may increase medical students’ risk for metabolic dysfunction-associated fatty liver disease (MAFLD) and non-alcoholic fatty pancreatic disease (NAFPD). This study aims to investigate how these lifestyle factors affect liver and pancreas health in preclinical medical students using diagnostic ultrasound imaging. Methods/Study Population: Using diagnostic ultrasound imaging, we propose a research study to evaluate the anatomical changes of the liver and pancreas associated with lifestyle among medical students in UCC. Forty-two (42) medical students from the Central University of the Caribbean who are in their preclinical years will be recruited to perform an abdominal ultrasound. To measure the diameter of the right liver lobe, we will employ the craniocaudal measurement method established by Riestra. et al. (2018). The parameter established by Rumack et al. (2011) will be utilized to assess liver texture and categories by Lee JS et al. (2009) to pancreas fat infiltration grades. Results/Anticipated Results: This study expects to reveal a significant correlation between the lifestyles of preclinical medical students and the health of their liver and pancreas, particularly in size and texture. We anticipate identifying specific lifestyle factors – such as dietary habits and physical activity levels – that contribute to the prevalence of hepatic and pancreatic steatosis. Additionally, we expect to highlight the need for targeted interventions to promote healthier lifestyles among medical students to mitigate risks associated with MAFLD and NAFPD. Discussion/Significance of Impact: This study is significant for monitoring changes in liver and pancreas health, preventing complications, and improving health quality while reducing future costs. It may guide the creation of tailored wellness programs for medical students, enhancing their well-being and contributing to better healthcare practices and educational strategies.

We present evidence of a direct social context effect on decision-making under uncertainty: the gender composition of those in the room when making individual risky decisions significantly alters choices even when the actions or presence of others are not payoff relevant. In our environment, decision makers do not know the choices made by others, nor can they be inferred from the experiment. We find that women become more risk taking as the proportion of men in the room increases, but the behavior of men is unaffected by who is present. We discuss some potential mechanisms for this result and conjecture it is driven by women being aware of the social context and imitating the expected behavior of others. Our results imply that the environment in which individual decisions are made can change expressed preferences and that aggregate behavior may be context dependent.

We provide a generalized revealed preference test for quasilinear preferences. The test applies to nonlinear budget sets and non-convex preferences as those found in taxation and nonlinear pricing contexts. We study the prevalence of quasilinear preferences in a laboratory real-effort task experiment with nonlinear wages. The experiment demonstrates the empirical relevance of our test. We find support for either convex (non-separable) preferences or quasilinear preferences but weak support for the hypothesis of both quasilinear and convex preferences.

We present experimental evidence on the interplay between strategic uncertainty and equilibrium selection in stable matching mechanisms. In particular, we apply a version of risk-dominance to compare the riskiness of “truncation” against other strategies that secure against remaining unmatched. By keeping subjects’ ordinal preferences fixed while changing their cardinal representation, our experimental treatments vary the risk-dominant prediction. We find that both truth-telling and truncation are played more often when they are risk-dominant. In both treatments, however, truncation strategies are played more often in later rounds of the experiment. Our results also shed light on several open questions in market design.

This article presents a bioinspired pneumatic soft actuator designed to mimic the flexo-extension movement of the human finger, with a particular focus on stiffness modulation through granular jamming. Three-chamber geometries – honeycomb, rectangular, and half-round – were evaluated to optimize curvature performance, utilizing Mold Star 15 Slow elastomer for actuator fabrication. Granular jamming, both passive and active, was implemented within the inextensible layer using chia and quinoa grains to enhance stiffness modulation. Experimental results revealed that the honeycomb geometry most closely aligned with the natural index finger trajectory. Stiffness evaluations demonstrated a range of 0–0.47 N/mm/° for quinoa and 0–0.9 N/mm/° for chia. The actuator’s force output increased by 16% for quinoa and 71% for chia compared to the nonjammed configuration. This enhanced performance is particularly beneficial for applications such as hand rehabilitation, where adaptive stiffness and force modulation are critical. Granular jamming, especially with active chia, provided superior adaptability for tasks requiring variable stiffness and resistance, making it a promising candidate for wearable robotic applications in rehabilitation.

Official Ecuadorian gross domestic product (GDP) data begin in 1950. Prior, only preliminary estimates were available, based on very scattered evidence and broad assumptions. In this paper, we estimate new GDP figures for Ecuador for 1900–50. These are based on the quantitative and qualitative information available for the period, using extensive primary and secondary sources. The new data series allows analysing Ecuador’s economic growth and structural change and comparing them to industrialised core countries and other countries in the region. Unlike previous estimates, our series shows a sustained divergence of Ecuador from the core countries during the first half of the 20th century.

Two new sites, identified during a survey of the Tajuña River Valley, central Iberia, show evidence of both flint extraction and working, specifically for the production of long blades. These are an important addition to the limited number of such sites known in Eurasia.

We evaluated 249 asymptomatic patients receiving antibiotics for urinary infection: 222 had asymptomatic pyuria and/or nitrituria (ASPN) and 133 had asymptomatic bacteriuria (ASB, growth ≥105 colony forming units/ml). ASPN identified 40% more cases of unnecessary antibiotics compared to ASB and may be a more comprehensive measure of unnecessary antibiotic use.

Antibiotic utilization for respiratory conditions (AXR) is a new Healthcare Effectiveness Data & Information Set ® (HEDIS®) measure designed to complement disease-specific metrics to improve outpatient antibiotic prescribing. Unique challenges include ensuring clinicians understand the metric and establishing appropriate goals within different health systems and service lines. Successful implementation requires awareness of the metric’s limitations and may be enhanced by co-reporting with condition-specific antibiotic use metrics to prioritize local interventions.

I argue that navigating Lingala represented a central part of many Zairians’ experiences of Mobutu’s regime (1965–97), causing linguistic change, shaping their relationships to state power, and influencing their experiences of the regime’s everyday authoritarianism. Mobutu’s regime imposed Lingala through informal language practices including political rallies, songs, and slogans, interactions with state agents, and Mobutu’s own practice of addressing audiences nation-wide in Lingala. Zairians navigated the regime’s imposition of Lingala in different, and often divergent ways along a spectrum from rejection and opposition to acquisition and embrace. Where some Zairians, especially Kiswahili speakers in the East, rejected Lingala and criticized the language — critiquing Mobutu’s authoritarian rule in the process — other Zairians, particularly people in the Kikongo and Ciluba national language zones adapted to Mobutu’s new linguistic dispensation by learning to speak and understand Lingala, improving their relationship with the state and facilitating life under Mobutu’s rule.

Different agencies have emphasized the need to evaluate current serological methods for screening patients with suspected urogenital schistosomiasis. However, there is still a lack of evidence regarding the most appropriate methods for this purpose. Here we assessed the diagnostic efficacy of a newly developed serological technique that utilizes the recombinant protein Sh-TSP-2, applied to the urine and serum of migrants suspected of having urogenital schistosomiasis. The sensitivity, specificity, positive and negative predictive values of an in-house enzyme-linked immunosorbent assay (ELISA) using the recombinant protein Sh-TSP-2 were analysed and compared with other commercial serological methods. Due to the limitations of microscopy as a perfect reference method, a latent class analysis (LCA) and composite reference standard (CRS) approach was used to determine the sensitivity and specificity of each test. According to the LCA model, the commercial tests NovaLisa® and immunochromatography test (ICT) immunoglobulin G–immunoglobulin M (IgG–IgM) presented the highest sensitivity (100%), whereas the Sh-TSP-2 serum ELISA test had 79.2%. The Sh-TSP-2 urine and serum ELISA tests had the highest specificities among the serological methods (87.5 and 75%, respectively). CRS modelling showed that the ICT IgG–IgM, NovaLisa® and Sh-TSP-2 serum tests led in sensitivity at 97.1, 88.6 and 71.4%, respectively, with all tests except that the ICT IgG–IgM test having a specificity >90%. Sh-TSP-2 has been validated as a screening tool for patients suspected of having urogenital schistosomiasis. Although commercial serological tests have shown higher sensitivities, Sh-TSP-2 could be valuable for confirming results from tests with lower specificity. Nevertheless, further studies with larger patient cohorts are necessary to fully verify its potential.

This paper presents the radiocarbon context of the megalithic monument El Amarejo 1, situated in the corridor of Almansa in the southern region of La Meseta in Spain. The monument was constructed using small and medium-sized masonry, comprising a short corridor and two separate chambers in which burials were carried out. The results of the 14C analyses of each of the 11 individuals documented indicate that the monument was in use between approximately 1900 and 1200 cal BC. Bayesian modeling of the radiocarbon dates allows for the proposition of hypotheses regarding the construction, utilisation dynamics, and abandonment of the monument. The combination of these new data with the analysis of the 14C dating of other burials from the Bronze Age of La Mancha reveals a complex and heterogeneous panorama. The evidence presented and analyzed in this paper suggests that burial practices associated with fortified settlements and their domestic areas shared space and time with the construction of megalithic monuments located near settlements.