This study examined associations between paternal, maternal, and dual-parental attention deficit hyperactivity disorder (ADHD) symptoms and child socioemotional functioning over the first two years of life, combined and separated by child sex. The sample included mothers (N = 3,207) and fathers (N = 3,211) from a prospective cohort in Canada. Parents completed the Adult ADHD Self-Report Scale within two weeks of childbirth. Children’s socioemotional functioning was assessed using the ASQ-SE at 6 months and the BITSEA at 12, 18, and 24 months. Paternal and maternal ADHD symptoms were associated with problems in child socioemotional development in the first two years of life, with significant differences based on parent and child sex. Paternal ADHD symptoms were associated with more socioemotional difficulties in boys (aOR 1.68, 95% CI 1.13–2.51) and fewer socioemotional difficulties in girls, while maternal ADHD symptoms were associated with more socioemotional problems in girls (aOR 2.09, 95% CI 1.24–3.52) and the entire sample, including both boys and girls, between 12 and 24 months. Dual-parental ADHD symptoms had the largest effect on socioemotional development (OR 4.43, 95% CI 1.14–17.16). Our findings provide evidence that exposure to paternal and maternal ADHD symptoms, especially when both parents exhibit symptoms, is associated with worse socioemotional outcomes during early childhood.

We present the Evolutionary Map of the Universe (EMU) survey conducted with the Australian Square Kilometre Array Pathfinder (ASKAP). EMU aims to deliver the touchstone radio atlas of the southern hemisphere. We introduce EMU and review its science drivers and key science goals, updated and tailored to the current ASKAP five-year survey plan. The development of the survey strategy and planned sky coverage is presented, along with the operational aspects of the survey and associated data analysis, together with a selection of diagnostics demonstrating the imaging quality and data characteristics. We give a general description of the value-added data pipeline and data products before concluding with a discussion of links to other surveys and projects and an outline of EMU’s legacy value.

Malnutrition is a major contributor to poorer health outcomes and continues to be sub-optimally identified and managed(1). The collection and availability of healthcare data is growing rapidly, strategies to harness data for optimal care is evolving(2). A hospital nutrition informatics platform that presents food supply and intake data and categorises risk using energy and protein thresholds has shown potential for identifying malnutrition risk(3). This study aimed to determine the Nutrition Dashboard’s capability to predict malnutrition through analysis of multiple energy and protein thresholds. Data were extracted from medical files and food service records for 267 patients over a four-month period, in a 99-bed hospital. Energy (2500 to 8000 kJ) and protein (30 to 90 g) thresholds were applied for Nutrition Dashboard categorisation by supply and intake of food. Deficits in estimated requirements (105 kJ and 0.75 g/kg/day)(4) were also applied as a comparative screening method. The association between Nutrition Dashboard categories and Malnutrition Screening Tool (MST) score was explored using generalised estimating equations. A total of 267 patients and 1908 days of data were analysed. Patients at risk of malnutrition (MST ≥ 2) was 39.2%, of those patients at increased risk, 57% received a dietitian referral. The use of weight based estimated requirements for Nutrition Dashboard categorisation was not statistically significant predictor of MST ≥ 2. Application of energy (≤ 6000 kJ) and protein (≤ 65 g) thresholds for categorisation was significant (X2 = 9.50, df = 3, p = 0.023). When 5000 kJ and 55 g of protein were used for categorisation, patients were more likely to be at nutritional risk (MST ≥ 2) if they were within low supply (OR 2.11, p = 0.002) and low intake (OR 2.23, p < 0.001) categories. When age, length of stay and weight were added to the modelling as covariates, the upper intake and protein thresholds of 5500 kJ and 60 g protein for Nutrition Dashboard categories one (low supply; OR 1.64, p = 0.046) and two (low intake; OR 1.64, p = 0.041) remained statistically significant predictors of at-risk nutrition status as measured by MST ≥ 2. Age and LOS were not significant predictors of MST ≥ 2, a static weight measure was found to be a predictor of at-risk nutrition screening (OR 0.97, CI = 0.95–0.97, p < 0.001). Nutrition Dashboard supply and intake categories were associated with an increased risk of malnutrition when categorised using thresholds up to 6000 kJ and 65 g protein. The Nutrition Dashboard presents nutrition risk surveillance information directly to dietitians with high reliability in an easily accessed, interactive format. Technologies such as the Nutrition Dashboard present innovative opportunities for dietitians to utilise nutrition informatics to enhance and optimise nutrition care.

There is increasing recognition that the welfare needs of cephalopod molluscs and decapod crustaceans are important. Current commercial practices involving these animals include a range of potential threats to their welfare, such as conditions of farming, capture, transport, and slaughter. This article draws from and updates our 2021 review for the UK Government, recommending a range of relatively simple and impactful changes that could benefit welfare while highlighting important research gaps that should be prioritised to facilitate the drafting of guidelines for best-practice.

Estimates of the mean and standard deviation of the tetrachoric correlation are compared with their expected values in several 2 × 2 tables. Significant bias in the mean is found when the minimum cell frequency is less than 5. Three formulas for the standard deviation are compared and guidelines given for their use.

The flow of a nematic liquid crystal in a Hele-Shaw cell with an electrically controlled viscous obstruction is investigated using both a theoretical model and physical experiments. The viscous obstruction is created by temporarily electrically altering the viscosity of the nematic in a region of the cell across which an electric field is applied. The theoretical model is validated experimentally for a circular cylindrical obstruction, demonstrating user-controlled flow manipulation of an anisotropic liquid within a heterogeneous single-phase microfluidic device.

Lower limb rehabilitation robots based on linkage-based mechanisms have recently drawn significant attention in the field due to their numerous advantages. The control of previously proposed linkage-based gait rehabilitation robotic orthoses has been achieved using constant speed control without consideration for the interaction forces. However, such an approach can be harmful to people with stroke since the level of disability varies among individuals, and it may cause potential injuries when excessive force is applied by the robot. To overcome this limitation and improve the rehabilitation process, it is necessary to recognize the force exerted by the person during walking and adjust the robot’s assistive torque accordingly, to provide synchronized motion. Thus, in this work, a human-cooperative approach based on a stiffness control strategy for the six-bar linkage-based gait rehabilitation robot is presented. The proposed methodology can serve as a solid foundation for developing a human-cooperative approach for linkage-based lower limb rehabilitation robotic orthoses. The control was validated and tested with eight healthy human subjects. As a result, customized robotic assistance with this mechanism can be provided during training to meet the individual needs of stroke patients, which can lead to increased engagement and contribution, thus improving treatment outcomes.

Biotite was altered by boiling in 0.2 M A1C13 solution, and the products were examined by X-ray powder and single-crystal diffraction, chemical analysis and thermogravimetry. The altered material is a 14 Å clay mineral with hydroxy-Al interlayers. It has a stacking sequence characteristic of vermiculite and its silicate layers are similar in chemical composition to trioctahedral vermiculite. The results of extracting the interlayer material with sodium citrate solution, X-ray examinations after heating and thermogravimetry show that the interlayer material is composed of Al associated with OH and H2O. The chemistry and kinetics of the alteration reaction and the orientational between the altered and original biotites are also discussed.

We give a short new proof of a recent result of Hanlon-Hicks-Lazarev about toric varieties. As in their work, this leads to a proof of a conjecture of Berkesch-Erman-Smith on virtual resolutions and to a resolution of the diagonal in the simplicial case.

Hospital placement is essential training for medical interns, involving shift work and high-pressure environments. This can increase physiological and psychological stress, which may be mediated by metabolites of microbial digestion(1). Nutrients of interest include those accessible to microbial digestion and associated with altered signalling within the microbiota-gut-brain axis (MGBA)(1). Fibre is fermented by gut microbes to produce short-chain fatty acids(2) and is associated with improved psychological outcomes(3). Tryptophan, a precursor to gut-derived serotonin(2), has been negatively associated with anxiety(4). Processed foods contain food additives, excess sugars, and saturated fats that may disrupt gut homeostasis(1) and impact psychological well-being(4). Lastly, total energy intake may determine the level of substrate available for microbial fermentation(2). Therefore, this research explores how microbiota-accessible food components interact with physical and psychological well-being in a cohort of medical interns undertaking their first-year of hospital placement. Participants were healthy medical interns, during first-year hospital placement (n = 21) from the Hunter New England Local Health District, NSW, Australia. Participants completed diet and wellbeing surveys at baseline and every 2 months over a 10-month period. 24-hour diet diaries were self-recorded from participants using a mobile application (Easy Diet Diary) and analysed using AusNut and the NOVA classification system of ultra-processed foods (ULP). Wellbeing surveys include depression, anxiety, stress scale (DASS), and PROMIS survey for mental (M), physical (P), and sleep well-being. Current data represents an ‘in-progress’ of the longitudinal data collection. This study utilised Spearman correlation and Tukey’s post hoc test for mixed methods analysis. From baseline to timepoint 3 (T3, 4 months) daily energy intake was consistent with cohort estimated energy requirements (EER). However, consumption ranged from 37% to 167% of EER, indicating a large variation of intakes. Energy consumed from ULP ranged from 30% to 34% (p = 0.6875). Baseline tryptophan intake (x¯ = 1139mg) was within the suggested target, whilst fibre intake (x¯ = 23g) was below the recommended intake. Neither saw significant changes from baseline to T3. Fibre intake was positively correlated with mental and physical well-being at baseline (x¯ = 23.1g, M: r = 0.474, p = 0.04, P: r = 0.608, p = 0.007), and timepoint 2 (x¯ = 31.5g, M: r = 0.647,p = 0.026, P: r = 0.780, p = 0.004) but not at T3. In addition, baseline consumption of sugar (x¯ = 18g) and poly-unsaturated fats (x¯ = 15g) were both negatively correlated with mental and physical well-being. Overall, no significant dietary changes were evident from baseline to mid-year collection in a first-year medical intern cohort during hospital placements. Fibre was significantly associated with mental and physical well-being, building on current understanding of fibre’s role in the MGBA. Planned metabolite analysis will explore the mechanisms of proposed microbiome-accessible nutrients alongside diet, well-being, and microbiota data. Findings from this study will identify how diet-microbiome interactions change under stress, with wider positive implications on intense workplace environments with the aim to preserve individual wellbeing.

Although food insecurity affects a significant proportion of young children in New Zealand (NZ)(1), evidence of its association with dietary intake and sociodemographic characteristics in this population is lacking. This study aims to assess the household food security status of young NZ children and its association with energy and nutrient intake and sociodemographic factors. This study included 289 caregiver and child (1-3 years old) dyads from the same household in either Auckland, Wellington, or Dunedin, NZ. Household food security status was determined using a validated and NZ-specific eight-item questionnaire(2). Usual dietary intake was determined from two 24-hour food recalls, using the multiple source method(3). The prevalence of inadequate nutrient intake was assessed using the Estimated Average Requirement (EAR) cut-point method and full probability approach. Sociodemographic factors (i.e., socioeconomic status, ethnicity, caregiver education, employment status, household size and structure) were collected from questionnaires. Linear regression models were used to estimate associations with statistical significance set at p <0.05. Over 30% of participants had experienced food insecurity in the past 12 months. Of all eight indicator statements, “the variety of foods we are able to eat is limited by a lack of money,” had the highest proportion of participants responding “often” or “sometimes” (35.8%). Moderately food insecure children exhibited higher fat and saturated fat intakes, consuming 3.0 (0.2, 5.8) g/day more fat, and 2.0 (0.6, 3.5) g/day more saturated fat compared to food secure children (p<0.05). Severely food insecure children had lower g/kg/day protein intake compared to food secure children (p<0.05). In comparison to food secure children, moderately and severely food insecure children had lower fibre intake, consuming 1.6 (2.8, 0.3) g/day and 2.6 (4.0, 1.2) g/day less fibre, respectively. Severely food insecure children had the highest prevalence of inadequate calcium (7.0%) and vitamin C (9.3%) intakes, compared with food secure children [prevalence of inadequate intakes: calcium (2.3%) and vitamin C (2.8%)]. Household food insecurity was more common in those of Māori or Pacific ethnicity; living in areas of high deprivation; having a caregiver who was younger, not in paid employment, or had low educational attainment; living with ≥2 other children in the household; and living in a sole-parent household. Food insecure young NZ children consume a diet that exhibits lower nutritional quality in certain measures compared to their food-secure counterparts. Food insecurity was associated with various sociodemographic factors that are closely linked with poverty or low income. As such, there is an urgent need for poverty mitigation initiatives to safeguard vulnerable young children from the adverse consequences of food insecurity.

Challenges with childhood emotion regulation may have origins in infancy and forecast later social and cognitive developmental delays, academic difficulties, and psychopathology. This study tested whether markers of emotion dysregulation in infancy predict emotion dysregulation in toddlerhood, and whether those associations depended on maternal sensitivity. When children (N = 111) were 7 months, baseline respiratory sinus arrhythmia (RSA), RSA withdrawal, and distress were collected during the Still Face Paradigm (SFP). Mothers’ reports of infant regulation and orientation and maternal sensitivity were also collected at that time. Mothers’ reports of toddlers’ dysregulation were collected at 18 months. A set of hierarchical regressions indicated that low baseline RSA and less change in RSA from baseline to stressor predicted greater dysregulation at 18 months, but only for infants who experienced low maternal sensitivity. Baseline RSA and RSA withdrawal were not significantly associated with later dysregulation for infants with highly sensitive mothers. Infants who exhibited low distress during the SFP and who had lower regulatory and orienting abilities at 7 months had higher dysregulation at 18 months regardless of maternal sensitivity. Altogether, these results suggest that risk for dysregulation in toddlerhood has biobehavioral origins in infancy but may be buffered by sensitive caregiving.