Female genital schistosomiasis (FGS) is a chronic disease manifestation of the waterborne parasitic infection Schistosoma haematobium that affects up to 56 million women and girls, predominantly in sub-Saharan Africa. Starting from early childhood, this stigmatizing gynaecological condition is caused by the presence of Schistosoma eggs and associated toxins within the genital tract. Schistosoma haematobium typically causes debilitating urogenital symptoms, mostly as a consequence of inflammation, which includes bleeding, discharge and lower abdominal pelvic pain. Chronic complications of FGS include adverse sexual and reproductive health and rights outcomes such as infertility, ectopic pregnancy and miscarriage. FGS is associated with prevalent human immunodeficiency virus and may increase the susceptibility of women to high-risk human papillomavirus infection. Across SSA, and even in clinics outside endemic areas, the lack of awareness and available resources among both healthcare professionals and the public means FGS is underreported, misdiagnosed and inadequately treated. Several studies have highlighted research needs and priorities in FGS, including better training, accessible and accurate diagnostic tools, and treatment guidelines. On 6 September, 2024, LifeArc, the Global Schistosomiasis Alliance and partners from the BILGENSA Research Network (Genital Bilharzia in Southern Africa) convened a consultative, collaborative and translational workshop: ‘Female Genital Schistosomiasis: Translational Challenges and Opportunities’. Its ambition was to identify practical solutions that could address these research needs and drive appropriate actions towards progress in tackling FGS. Here, we present the outcomes of that workshop – a series of discrete translational actions to better galvanize the community and research funders.

We present a re-discovery of G278.94+1.35a as possibly one of the largest known Galactic supernova remnants (SNRs) – that we name Diprotodon. While previously established as a Galactic SNR, Diprotodon is visible in our new Evolutionary Map of the Universe (EMU) and GaLactic and Extragalactic All-sky MWA (GLEAM) radio continuum images at an angular size of $3{{{{.\!^\circ}}}}33\times3{{{{.\!^\circ}}}}23$, much larger than previously measured. At the previously suggested distance of 2.7 kpc, this implies a diameter of 157$\times$152 pc. This size would qualify Diprotodon as the largest known SNR and pushes our estimates of SNR sizes to the upper limits. We investigate the environment in which the SNR is located and examine various scenarios that might explain such a large and relatively bright SNR appearance. We find that Diprotodon is most likely at a much closer distance of $\sim$1 kpc, implying its diameter is 58$\times$56 pc and it is in the radiative evolutionary phase. We also present a new Fermi-LAT data analysis that confirms the angular extent of the SNR in gamma rays. The origin of the high-energy emission remains somewhat puzzling, and the scenarios we explore reveal new puzzles, given this unexpected and unique observation of a seemingly evolved SNR having a hard GeV spectrum with no breaks. We explore both leptonic and hadronic scenarios, as well as the possibility that the high-energy emission arises from the leftover particle population of a historic pulsar wind nebula.

We present radio observations of the galaxy cluster Abell S1136 at 888 MHz, using the Australian Square Kilometre Array Pathfinder radio telescope, as part of the Evolutionary Map of the Universe Early Science program. We compare these findings with data from the Murchison Widefield Array, XMM-Newton, the Wide-field Infrared Survey Explorer, the Digitised Sky Survey, and the Australia Telescope Compact Array. Our analysis shows the X-ray and radio emission in Abell S1136 are closely aligned and centered on the Brightest Cluster Galaxy, while the X-ray temperature profile shows a relaxed cluster with no evidence of a cool core. We find that the diffuse radio emission in the centre of the cluster shows more structure than seen in previous low-resolution observations of this source, which appeared formerly as an amorphous radio blob, similar in appearance to a radio halo; our observations show the diffuse emission in the Abell S1136 galaxy cluster contains three narrow filamentary structures visible at 888 MHz, between $\sim$80 and 140 kpc in length; however, the properties of the diffuse emission do not fully match that of a radio (mini-)halo or (fossil) tailed radio source.

The crystal structure of bannisterite, a modulated, mica-like mineral species, of general composition Ca0.5(K,Na)0.5(Mn,Fe,Mg,Zn)10(Si,Al)16O38(OH)8·nH2O, has been solved and refined for specimens from Franklin Furnace, New Jersey (FF), and Broken Hill, Australia (BH). The crystals are mono-clinic in space group A2/a, with (for FF) a = 22.265(1) Å, b = 16.368(1) Å, c = 24.668(2) Å, β = 94.285(5)°; and (for BH) a = 22.286(1) Å, b = 16.386(1) Å, c = 24.575(2) Å, β = 94.355(7)°; Z = 8. Refinement with anisotropic thermal factors reached Rw = 0.034 (FF) and 0.039 (BH). Like stilpnomelane and ganophyllite, bannisterite has a modified 2:1 trioctahedral layer structure in which some of the tetrahedra are inverted towards the interlayer region and linked to inverted tetrahedra in the opposite layer. The octahedral sheet is strongly corrugated along b. The tetrahedral sheet consists of 5-, 6-, and 7-fold rings, and bond distance calculations indicate that Al is concentrated into two of the four inverted tetrahedra. The interlayer Ca, K, and H2O species are highly disordered, as indicated by anomalously large temperature factors and partial occupancies. Localized differences in the Al/Si arrangements in the inverted tetrahedra induce disorder among the interlayer cations.

Radiocarbon data are the most commonly used chronometric measurement technique in archaeology. The introduction of the radiocarbon method offered new potential for independent, internationalized research projects. Today millions of radiocarbon measurements exist globally. However, the many strengths of radiocarbon for research in archaeology have also created an internationally significant challenge in heritage practice. How can we attempt to curate huge volumes of radiocarbon “legacy” data in systematic ways that facilitate interdisciplinary, international research? How can we contend with a dataset that is rapidly scalable, and needs to be kept live—updated, validated, curated, and related to existing national archives and data systems—beyond the timescale of any individual project? In this paper we introduce an international project, “Project Radiocarbon; Big Data, integrated cross-national heritage histories”, working across the historic environment sector in Ireland and the United Kingdom, that is developing a solution to these issues. We argue that we need to think critically about how we classify and curate radiocarbon data, to render them interoperable and findable. Such work requires inter-sector approaches to ensure sustainability and scalability, and to anticipate the increasing value of these data into the future.

In a conventional experiment, scientists typically aim to learn about target systems by manipulating source systems of the same material type. In an analogue quantum simulation, by contrast, scientists typically aim to learn about target quantum systems of one material type via an experiment on a source quantum system of a different material type. In this article, we argue that such inferences can be justified by reference to source and target quantum systems being of the same empirical type. We illustrate this novel experimental practice of wavefunction engineering with reference to the example of Bose–Hubbard systems.

Many traditional regions are being transformed as industries restructure. Paradoxically, the global economic downturn offers opportunities to innovate on policies to regenerate areas experiencing deindustrialisation, with one emerging focus being the development of ‘green skills’ to facilitate the transition of these places to ‘green economies’. In this article, we explore similar policy objectives (i.e. regeneration activity based (in part) on green economy transitions) across three deindustrialising/deindustrialised regions – Appalachia (United States), Ruhr (Germany) and the Valleys (South Wales) – to provide an account of the ways in which different regions with similar industrial pasts diverge in their approach to moving towards greener futures. Our argument is that the emphasis in such transitions should be the creation of ‘decent’ jobs, with new economic activity and employment initiatives embracing a ‘high road’ (i.e. high skill/high pay/high quality) trajectory. Utilising a ‘varieties of capitalism’ analysis, we contend that an effective, socially inclusive and ‘high road’ transition is more likely to emerge within co-ordinated market economy contexts, for example, Germany, than within the liberal market economy contexts of, for example, the United States and United Kingdom. In identifying the critical success factors leading to ‘high road’ green economy, the implications for any such transition within the liberal market economy context of Australia are highlighted.

Brazil and Mexico occupy distinctive positions in the structure of the capitalist world economy. They bear little resemblance to the classic model of a “peripheral” country: they are too industrialized, having many of the modern industries typically found only at the center of the world economy; they supply themselves with too large a share of the finished goods consumed domestically; their exports are too diversified and include too many manufactured items; and they have developed unusually strong states with sophisticated administrative apparatuses capable of promoting and protecting local interests. But neither do Brazil and Mexico possess the characteristics commonly associated with “developed” or “core” nations. Their gross domestic product per capita is far below that of the United States, Japan, or almost any of the countries of Western Europe; their distributions of income are highly skewed compared to those of the developed countries; they are recipient rather than source countries of foreign investment; they are debtor rather than creditor nations; and they are on the receiving rather than the originating end of product innovation and new production techniques.

This combined numerical/laboratory study investigates the effect of stratification form on the shoaling characteristics of internal solitary waves propagating over a smooth, linear topographic slope. Three stratification types are investigated, namely (i) thin tanh (homogeneous upper and lower layers separated by a thin pycnocline), (ii) surface stratification (linearly stratified layer overlaying a homogeneous lower layer) and (iii) broad tanh (continuous density gradient throughout the water column). It is found that the form of stratification affects the breaking type associated with the shoaling wave. In the thin tanh stratification, good agreement is seen with past studies. Waves over the shallowest slopes undergo fission. Over steeper slopes, the breaking type changes from surging, through collapsing to plunging with increasing wave steepness $A_w/L_w$ for a given topographic slope, where $A_w$ and $L_w$ are incident wave amplitude and wavelength, respectively. In the surface stratification regime, the breaking classification differs from the thin tanh stratification. Plunging dynamics is inhibited by the density gradient throughout the upper layer, instead collapsing-type breakers form for the equivalent location in parameter space in the thin tanh stratification. In the broad tanh profile regime, plunging dynamics is likewise inhibited and the near-bottom density gradient prevents the collapsing dynamics. Instead, all waves either fission or form surging breakers. As wave steepness in the broad tanh stratification increases, the bolus formed by surging exhibits evidence of Kelvin–Helmholtz instabilities on its upper boundary. In both two- and three-dimensional simulations, billow size grows with increasing wave steepness, dynamics not previously observed in the literature.

We present the data and initial results from the first pilot survey of the Evolutionary Map of the Universe (EMU), observed at 944 MHz with the Australian Square Kilometre Array Pathfinder (ASKAP) telescope. The survey covers $270 \,\mathrm{deg}^2$ of an area covered by the Dark Energy Survey, reaching a depth of 25–30 $\mu\mathrm{Jy\ beam}^{-1}$ rms at a spatial resolution of $\sim$11–18 arcsec, resulting in a catalogue of $\sim$220 000 sources, of which $\sim$180 000 are single-component sources. Here we present the catalogue of single-component sources, together with (where available) optical and infrared cross-identifications, classifications, and redshifts. This survey explores a new region of parameter space compared to previous surveys. Specifically, the EMU Pilot Survey has a high density of sources, and also a high sensitivity to low surface brightness emission. These properties result in the detection of types of sources that were rarely seen in or absent from previous surveys. We present some of these new results here.

Vulture populations are in severe decline across Africa and prioritization of geographic areas for their conservation is urgently needed. To do so, we compiled three independent datasets on vulture occurrence from road-surveys, GPS-tracking, and citizen science (eBird), and used maximum entropy to build ensemble species distribution models (SDMs). We then identified spatial vulture conservation priorities in Ethiopia, a stronghold for vultures in Africa, while accounting for uncertainty in our predictions. We were able to build robust distribution models for five vulture species across the entirety of Ethiopia, including three Critically Endangered, one Endangered, and one Near Threatened species. We show that priorities occur in the highlands of Ethiopia, which provide particularly important habitat for Bearded Gypaetus barbatus, Hooded Necrosyrtes monachus, Rüppell’s Gyps rüppelli and White-backed Gyps africanus Vultures, as well as the lowlands of north-eastern Ethiopia, which are particularly valuable for the Egyptian Vulture Neophron percnopterus. One-third of the core distribution of the Egyptian Vulture was protected, followed by the White-backed Vulture at one-sixth, and all other species at one-tenth. Overall, only about one-fifth of vulture priority areas were protected. Given that there is limited protection of priority areas and that vultures range widely, we argue that measures of broad spatial and legislative scope will be necessary to address drivers of vulture declines, including poisoning, energy infrastructure, and climate change, while considering the local social context and aiding sustainable development.