Current evidence underscores a need to transform how we do clinical research, shifting from academic-driven priorities to co-led community partnership focused programs, accessible and relevant career pathway programs that expand opportunities for career development, and design of trainings and practices to develop cultural competence among research teams. Failures of equitable research translation contribute to health disparities. Drivers of this failed translation include lack of diversity in both researchers and participants, lack of alignment between research institutions and the communities they serve, and lack of attention to structural sources of inequity and drivers of mistrust for science and research. The Duke University Research Equity and Diversity Initiative (READI) is a program designed to better align clinical research programs with community health priorities through community engagement. Organized around three specific aims, READI-supported programs targeting increased workforce diversity, workforce training in community engagement and cultural competence, inclusive research engagement principles, and development of trustworthy partnerships.

The U.S. Department of Agriculture–Agricultural Research Service (USDA-ARS) has been a leader in weed science research covering topics ranging from the development and use of integrated weed management (IWM) tactics to basic mechanistic studies, including biotic resistance of desirable plant communities and herbicide resistance. ARS weed scientists have worked in agricultural and natural ecosystems, including agronomic and horticultural crops, pastures, forests, wild lands, aquatic habitats, wetlands, and riparian areas. Through strong partnerships with academia, state agencies, private industry, and numerous federal programs, ARS weed scientists have made contributions to discoveries in the newest fields of robotics and genetics, as well as the traditional and fundamental subjects of weed–crop competition and physiology and integration of weed control tactics and practices. Weed science at ARS is often overshadowed by other research topics; thus, few are aware of the long history of ARS weed science and its important contributions. This review is the result of a symposium held at the Weed Science Society of America’s 62nd Annual Meeting in 2022 that included 10 separate presentations in a virtual Weed Science Webinar Series. The overarching themes of management tactics (IWM, biological control, and automation), basic mechanisms (competition, invasive plant genetics, and herbicide resistance), and ecosystem impacts (invasive plant spread, climate change, conservation, and restoration) represent core ARS weed science research that is dynamic and efficacious and has been a significant component of the agency’s national and international efforts. This review highlights current studies and future directions that exemplify the science and collaborative relationships both within and outside ARS. Given the constraints of weeds and invasive plants on all aspects of food, feed, and fiber systems, there is an acknowledged need to face new challenges, including agriculture and natural resources sustainability, economic resilience and reliability, and societal health and well-being.

Exoskeletons that assist the hip, knee, and ankle joints have begun to improve human mobility, particularly by reducing the metabolic cost of walking. However, direct comparisons of optimal assistance of these joints, or their combinations, have not yet been possible. Assisting multiple joints may be more beneficial than the sum of individual effects, because muscles often span multiple joints, or less effective, because single-joint assistance can indirectly aid other joints. In this study, we used a hip–knee–ankle exoskeleton emulator paired with human-in-the-loop optimization to find single-joint, two-joint, and whole-leg assistance that maximally reduced the metabolic cost of walking. Hip-only and ankle-only assistance reduced the metabolic cost of walking by 26 and 30% relative to walking in the device unassisted, confirming that both joints are good targets for assistance (N = 3). Knee-only assistance reduced the metabolic cost of walking by 13%, demonstrating that effective knee assistance is possible (N = 3). Two-joint assistance reduced the metabolic cost of walking by between 33 and 42%, with the largest improvements coming from hip-ankle assistance (N = 3). Assisting all three joints reduced the metabolic cost of walking by 50%, showing that at least half of the metabolic energy expended during walking can be saved through exoskeleton assistance (N = 4). Changes in kinematics and muscle activity indicate that single-joint assistance indirectly assisted muscles at other joints, such that the improvement from whole-leg assistance was smaller than the sum of its single-joint parts. Exoskeletons can assist the entire limb for maximum effect, but a single well-chosen joint can be more efficient when considering additional factors such as weight and cost.

We discuss the first detection of deuterated water (HDO) in extragalactic hot cores. The HDO 211–212 line has been detected with the Atacama Large Millimeter/submillimeter Array (ALMA) toward hot cores N 105–2 A and 2 B in the N 105 star-forming region in the low-metallicity Large Magellanic Cloud (LMC), the nearest star-forming galaxy. We compared the HDO line luminosity (LHDO) measured toward two hot cores in N 105 to those observed toward a sample of 17 Galactic hot cores and found that the observed values of LHDO for the LMC hot cores fit very well into the LHDO trends with Lbol and metallicity observed toward the Galactic hot cores. Our results indicate that LHDO seems to be largely dependent on the source luminosity, but metallicity also plays a role. We provide a rough estimate of the H2O column density and abundance ranges toward N 105–2 A and 2 B by assuming that HDO/H2O toward the LMC hot cores is the same as that observed in the Milky Way; the obtained values are systematically lower than those measured in the Galactic hot cores. The spatial distribution and velocity structure of the HDO emission in N 105–2 A is consistent with HDO being the product of the low-temperature dust grain chemistry.

Substantial progress has been made in the standardization of nomenclature for paediatric and congenital cardiac care. In 1936, Maude Abbott published her Atlas of Congenital Cardiac Disease, which was the first formal attempt to classify congenital heart disease. The International Paediatric and Congenital Cardiac Code (IPCCC) is now utilized worldwide and has most recently become the paediatric and congenital cardiac component of the Eleventh Revision of the International Classification of Diseases (ICD-11). The most recent publication of the IPCCC was in 2017. This manuscript provides an updated 2021 version of the IPCCC.

The International Society for Nomenclature of Paediatric and Congenital Heart Disease (ISNPCHD), in collaboration with the World Health Organization (WHO), developed the paediatric and congenital cardiac nomenclature that is now within the eleventh version of the International Classification of Diseases (ICD-11). This unification of IPCCC and ICD-11 is the IPCCC ICD-11 Nomenclature and is the first time that the clinical nomenclature for paediatric and congenital cardiac care and the administrative nomenclature for paediatric and congenital cardiac care are harmonized. The resultant congenital cardiac component of ICD-11 was increased from 29 congenital cardiac codes in ICD-9 and 73 congenital cardiac codes in ICD-10 to 318 codes submitted by ISNPCHD through 2018 for incorporation into ICD-11. After these 318 terms were incorporated into ICD-11 in 2018, the WHO ICD-11 team added an additional 49 terms, some of which are acceptable legacy terms from ICD-10, while others provide greater granularity than the ISNPCHD thought was originally acceptable. Thus, the total number of paediatric and congenital cardiac terms in ICD-11 is 367. In this manuscript, we describe and review the terminology, hierarchy, and definitions of the IPCCC ICD-11 Nomenclature. This article, therefore, presents a global system of nomenclature for paediatric and congenital cardiac care that unifies clinical and administrative nomenclature.

The members of ISNPCHD realize that the nomenclature published in this manuscript will continue to evolve. The version of the IPCCC that was published in 2017 has evolved and changed, and it is now replaced by this 2021 version. In the future, ISNPCHD will again publish updated versions of IPCCC, as IPCCC continues to evolve.

Microstructural analysis and bulk dielectric property analysis (real and imaginary permittivity at 95 GHz) were performed at temperatures ranging from 25 to 550 °C for ceramic composites comprising a hot-pressed aluminum nitride matrix (containing yttria and trace carbon as sintering additives) with molybdenum powder as a millimeter-wave radiation-absorbing additive. Loading percentages in the range of 0.25 vol% to 4.0 vol% Mo were characterized. For the temperature regime evaluated, the temperature-related changes in real and imaginary components of permittivity were found to be relatively modest compared with those driven by Mo loading. Energy-dispersive X-ray spectroscopic analysis of Mo grains and surrounding regions showed the presence of a mixed-phase layer, containing Mo2C, at the AlN–Mo interface. The Mo2C-containing mixed-phase layer, typically a few micrometers thick, surrounded the Mo grains. Further characterization of this mixed-phase layer is required to determine its contribution to the dielectric properties of the composite.

The increased use of insecticide seed treatments in rice has raised many questions about the potential benefits of these products. In 2014 and 2015, a field experiment was conducted near Stuttgart and Lonoke, AR, to evaluate whether an insecticide seed treatment could possibly lessen injury from acetolactate synthase (ALS)–inhibiting herbicides in imidazolinone-resistant (IR) rice. Two IR cultivars were tested (a hybrid, ‘CLXL745’, and an inbred, ‘CL152’), with and without an insecticide seed treatment (thiamethoxam). Four different herbicide combinations were evaluated: a nontreated control, two applications of bispyribac-sodium (hereafter bispyribac), two applications of imazethapyr, and two applications of imazethapyr plus bispyribac. The first herbicide application was to two- to three-leaf rice, and the second immediately prior to flooding (one- to two-tiller). At both 2 and 4 wk after final treatment (WAFT), the sequential applications of imazethapyr or bispyribac plus imazethapyr were more injurious to CLXL745 than CL152. This increased injury led to decreased groundcover 3 WAFT. Rice treated with thiamethoxam was less injured than nontreated rice and had improved groundcover and greater canopy heights. Even with up to 32% injury, the rice plants recovered by the end of the growing season, and yields within a cultivar were similar with and without a thiamethoxam seed treatment across all herbicide treatments. Based on these results, thiamethoxam can partially protect rice from injury caused by ALS-inhibiting herbicides as well as increase groundcover and canopy height; that is, the injury to rice never negatively affected yield.

In order to begin to evaluate and model the suitability of high temperature ceramic composites, such as AlN:Mo, as susceptor materials for power beaming applications, the electromagnetic, thermal, and mechanical properties of the material must be known at elevated temperatures. Work reported here focuses on the development of thermal property datasets for AlN:Mo composites ranging from 0.25% to 4.0% Mo by volume. To calculate thermal conductivity of the AlN:Mo composite series, specific heat capacity, thermal diffusivity, and density data were acquired. The calculated specific heat capacity, Cp, of the set of AlN:Mo composites was, on average, found to be approximately 803 J/kgK at 100 °C and to increase to approximately 1133 J/kgK at 1000 °C, with all values to be within +/- 32 J/kgK of the average at a given temperature. These calculated specific heat capacity values matched values derived from DSC measurements to within the expected error of the measurements. Measured thermal diffusivity, α, of the set of AlN:Mo composites was, on average, found to be approximately 3.93 x 10-1 cm2/s at 100 °C and to increase to approximately 9.80 x 10-2 cm2/s at 1000 °C, with all values within +/- 1.84 x 10-2 cm2/s of the average at a given temperature. Thermal conductivity, k, for the set of AlN:Mo composites was found to be approximately 108 W/mK at 100 °C and to decrease to approximately 38 W/mK at 1000 °C, with all values within +/- 5.3 W/mK of the average at a given temperature. Data trends show that increasing Mo content correlates to lower values of of Cp, α, and k at a given temperature.

Each year there are multiple reports of drift occurrences, and the majority of drift complaints in rice are from imazethapyr or glyphosate. In 2014 and 2015, multiple field experiments were conducted near Stuttgart, AR, and near Lonoke, AR, to evaluate whether insecticide seed treatments would reduce injury from glyphosate or imazethapyr drift or decrease the recovery time following exposure to a low rate of these herbicides. Study I was referred to as the “seed treatment study,” and Study II was the “drift timing study.” In the seed treatment study the conventional rice cultivar ‘Roy J’ was planted, and herbicide treatments included imazethapyr at 10.5 g ai ha–1, glyphosate at 126 g ae ha–1, or no herbicide. Each plot had either a seed treatment of thiamethoxam, clothianidin, chlorantraniliprole, or no insecticide seed treatment. The herbicides were applied at the two- to three-leaf growth stage. Crop injury was assessed 1, 3, and 5 wk after application. Averaged over site-years, thiamethoxam-treated rice had less injury than rice with no insecticide seed treatment at each rating, along with an increased yield. Clothianidin-treated rice had an increased yield over no insecticide seed treatment, but the reduction in injury for both herbicides was less pronounced than in the thiamethoxam-treated plots. Overall, chlorantraniliprole was generally the least effective of the three insecticides in reducing injury from either herbicide and in protecting rice yield potential. A second experiment conducted at Stuttgart, AR, was meant to determine whether damage to rice from glyphosate and imazethapyr was influenced by the timing (15, 30, and 45 d after planting) of exposure to herbicides for thiamethoxam-treated and nontreated rice. There was an overall reduction in injury with the use of thiamethoxam, but the reduction in injury was not dependent on the timing of the drift event. Reduction in damage from physical drift of glyphosate and imazethapyr as well as increased yields over the absence of an insecticide seed treatment appear to be an added benefit.

Bentazon degradation in soil typically proceeds with development of bound residue. Low sorption of bentazon suggests that this residue consists of degradation products; however, there is little data on the sorption behavior of these products. This study was undertaken to determine the sorption of bentazon and the degradation products 2-amino-N-isopropyl benzamide, 2-aminobenzoic acid, and N-methyl bentazon in Dundee silt loam and Sharkey clay, two common agricultural soils of the Mississippi Delta. Greater sorption of bentazon and degradation products in the Sharkey soil was related to finer texture and higher organic C content. Isotherms were nonlinear, with sorption increasing in the order bentazon ≪ 2-amino-N-isopropyl benzamide < N- methyl bentazon. In general, methanol extraction indicated reversible sorption of these compounds. Therefore, it is unlikely that sorption of either 2-amino-N-isopropyl benzamide or N-methyl bentazon contributes to bound residue. In contrast, essentially all of the 14C sorbed from radiolabeled 2-aminobenzoic acid solution remained bound after methanol extraction. However, due to degradation of 2-aminobenzoic acid, it was not possible to conclude the extent to which this compound contributed to bound 14C. Sorption of 14C from 2-aminobenzoic acid exceeded that of N-methyl bentazon, and at low initial concentrations (≤ 20 μM) was nearly 1000-fold greater than bentazon sorption.

The critical period of weed control is the portion of the life cycle of a crop during which it must be kept weed-free to prevent yield loss due to weed interference. The advent of herbicide-resistant canola (Brassica napus L.) varieties in western Canada has meant that there are now more options for postemergence weed control in canola, and this has prompted increased interest in identifying the optimum timing for weed control in this crop. A critical period experiment was conducted at three locations in southern Manitoba in 1998 and 1999, and it consisted of two sets of treatments. In the first set of treatments, the crop was kept weed-free for increasing lengths of time to determine when emerging weeds would no longer reduce crop yield. In the second set of treatments, weeds were permitted to grow in the crop for increasing lengths of time to determine when weeds emerging with the crop began irrevocably to reduce crop yield. Results of the experiments indicated that canola must be kept weed-free in most cases until the four-leaf stage of the crop (17–38 days after crop emergence [DAE]) and, in one early-seeded experiment, until the six-leaf stage of the crop (41 DAE), in order to prevent >10% yield loss. After the four- to six-leaf stage of the canola crop, few weeds emerged, and late-emerging weeds accumulated little shoot biomass. Weeds needed to be removed by the four-leaf stage of the crop (17–38 DAE) to prevent >10% yield loss due to weed interference. In all but the early-seeded experiment, the critical weed-free period and the critical time of weed removal overlapped, such that a single weed removal at the four-leaf stage of the crop would have been sufficient to prevent >10% yield loss. This information will be useful for providing weed control recommendations to canola producers.

Reduced-tillage systems including no-tillage and striptillage have well-known benefits for conserving and improving soils, protecting vulnerable crops from extreme weather events, and reducing labor and fuel costs associated with full-width inversion tillage (Franzluebbers 2002, 2005; Parsch et al. 2001; Pesant et al. 1987; Spargo et al. 2008). Despite these benefits, reduced-tillage has not been widely adopted in many cropping systems due in part to the increased difficulty of managing weeds when tillage is not used. Not surprisingly, adoption of reduced-tillage has occurred primarily in crops for which low-cost, effective herbicides are available, including glyphosate-resistant soybean [Glycine max (L.) Merr.], corn (Zea mays L.), cotton (Gossypium hirsutum L.), and sugarbeets (Beta vulgaris L.) (Horowitz et al. 2010; Tarkalson et al. 2012). Increased use of a narrow range of herbicides in these cropping systems has exacerbated problems of herbicide resistance (Duke and Powles 2009; Heap 2012). Conversely, adoption of reduced-tillage has been limited in crops where effective herbicides are not available (e.g. in “minor crops” like vegetables) or prohibited (e.g. in organic production systems). Research aimed at identifying nonchemical approaches to managing weeds in reduced-tillage production systems has the potential to increase adoption of reducedtillage while minimizing herbicide use and selection pressure for herbicide resistance in production systems currently using reduced tillage (Figure 1).

Avena fatua seeds remaining on the plant at harvest and taken into the combine harvester may be dispersed over large areas. The objective of this study was to characterize the development of A. fatua in comparison to spring Triticum aestivum. As part of this objective, the rate of seed shed in A. fatua relative to development of T. aestivum was determined. Avena fatua and T. aestivum had similar phyllochron intervals within locations but differed between locations. Plant development as measured by the Zadoks plant development scale was consistent within plant species between locations. Seed shed in A. fatua was also consistent between locations. Most of the seed shed occurred within 2 wk, and the cumulative seed shed followed a sigmoidal pattern. The seed shed occurred as T. aestivum was ripening, and the percentage of seed shed appears to be related to the water content of the T. aestivum spike. Because of this relationship, the proportion of seed remaining on A. fatua at harvest could be managed by changing the timing of crop harvest.

Many studies on the adoption of precision technologies have generally used logit models to explain the adoption behavior of individuals. This study investigates factors affecting the intensity of precision agriculture technologies adopted by cotton farmers. Particular attention is given to the role of spatial yield variability on the number of precision farming technologies adopted, using a count data estimation procedure and farm-level data. Results indicate that farmers with more within-field yield variability adopted a higher number of precision agriculture technologies. Younger and better educated producers and the number of precision agriculture technologies used were significantly correlated. Finally, farmers using computers for management decisions also adopted a higher number of precision agriculture technologies.

Precision farming information demanded by cotton producers is provided by various suppliers, including consultants, farm input dealerships, University Extension systems, and media sources. Factors associated with the decisions to select among information sources to search for precision farming information are analyzed using a multivariate probit regression accounting for correlation among the different selection decisions. Factors influencing these decisions are age, education, and income. These findings should be valuable to precision farming information providers who may be able to better meet their target clientele needs.

The Wisconsin Economic Impact Modeling System, a conjoined input-output/econometric model of Wisconsin counties, is used to simulate the economic and fiscal impact of two alternative residential development patterns. Under the first scenario, the impact of migrating retirees on a small tri-county region in northern Wisconsin is examined. Under the second scenario, the impact of the migration of younger families with children is examined. A comparison-contrast between the two scenarios demonstrates that the characteristics of the migrating household can have a significant impact on the nature of the impacts.

This study identified the factors that influenced whether farmers in theSoutheastern United States perceived an improvement in environmental qualityfrom adopting precision farming technologies (PFTs). Farmers with largerfarms or higher yields were more likely to believe that they observedpositive externalities associated with PFTs. Farmers who found PFTsprofitable or who believed input reduction was important had higherprobabilities whereas those with higher incomes or who were more dependenton farm income were less likely to perceive such benefits. Interestingly,the importance of environmental quality and length of time using PFTs werenot found to affect the probability of perceiving an improvement inenvironmental quality.

Probit analysis identified factors that influence the adoption of precision farming technologies by Southeastern cotton farmers. Younger, more educated farmers who operated larger farms and were optimistic about the future of precision farming were most likely to adopt site-specific information technology. The probability of adopting variable-rate input application technology was higher for younger farmers who operated larger farms, owned more of the land they farmed, were more informed about the costs and benefits of precision farming, and were optimistic about the future of precision farming. Computer use was not important, possibly because custom hiring shifts the burden of computer use to agribusiness firms.