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Clinical Neuroendocrinology: An Introduction, second edition, is thoroughly updated and continues to fulfil the continued need for a concise, introductory description of the human neuroendocrine system in health and disease. The clinical implications of basic human neuroendocrinology are described and presented along with real clinical case studies and a selection of review questions in each chapter to help cement readers' knowledge. Recent important advances are revealed in new figures and up-to-date references from the clinical literature, such as the discovery of kisspeptin, its use in the treatment of amenorrhea and its application in IVF. The authors also describe the development of GLP-1 agonists, which are now available for the treatment of obesity. This is a key text for senior medical students deciding on a specialty, as well as residents and clinical fellows who are embarking on their chosen fields. The book also provides crucial clinical context for biomedical science graduate students and clinicians.
This updated fourth edition brings together the latest knowledge and evidence base across the wide range of psychiatric and behavioural disorders presenting in people with an intellectual disability. Featuring chapters contributed by international experts, researchers, and academics from a broad range of disciplines, the book reflects current knowledge and best practice in the field, with a particular focus on contemporary approaches to clinical assessment and treatment. This edition introduces new and expanded coverage of key advances in psychiatry, including neurodevelopmental disorders such as autism spectrum disorder and ADHD, developments in neuroscience, genetics, and biomarkers, and a strengthened emphasis on service user and family involvement and co-production to inform service delivery. An essential hands-on reference book for psychiatrists and the wider group of professionals working across mental health and intellectual disability services. Also, an excellent resource for graduates, doctoral students, researchers and academics studying the range of neurodevelopmental disorders.
The intervention of States in legal proceedings touches upon some of the most beguiling questions in international dispute settlement. These include questions of treaty interpretation, obligations erga omnes, the sources of judicial power and rulemaking, the nature of incidental proceedings, the Monetary Gold doctrine of indispensable parties, cross-fertilization between judicial and arbitral bodies, and principles of jurisdiction, party autonomy, and res judicata. As jurists and scholars tend to address these questions in isolation, however, each development in third-State practice has raised unimagined issues of first impression-such as the 2022 declarations of dozens of States exploring mass intervention before the International Court of Justice in Ukraine v. Russia, and the participation of neighbouring States without China's presence in the 2016 South China Sea arbitration. By applying conceptual, comparative, and historical approaches to international justice, this book instead offers a uniquely holistic assessment of the practice and prospective development of intervention.
The circular economy is rapidly emerging as a foundational framework for economic development, shaping government policy and industrial transformation around the world. Written for students and practitioners alike, this book provides a strategic roadmap for business model development in alignment with circular economy principles. Readers will learn how to utilize resources effectively, apply design thinking, manage continuous improvement, and optimize impact by working more efficiently, both inside and outside corporate supply chains. Each chapter presents cutting-edge frameworks and real-world examples of success in the circular economy, while encouraging active learning and collaborative discussion through insight boxes, review questions, project suggestions, video discussions, and further reading. Instructors are supported by chapter PowerPoints and additional case studies, and students can find links to readings, videos and other resources, as well as downloadable worksheets from the book's appendices.
The second edition of Computational Photonics, now An Introduction with Python, provides a comprehensive guide to the modelling and numerical analysis of modern photonic devices and systems. Combining the theoretical foundations of optics and electromagnetism with practical computational methods, the book enables readers to simulate and explore real photonic phenomena through hands-on numerical experiments. The text covers key topics including optical waveguides, optical fibres, semiconductor lasers, optical amplifiers, receivers, beam propagation methods (BPM), finite-difference time-domain (FDTD) simulations, solitons, solar cells, metamaterials, and includes a new chapter on plasmonics. This fully revised second edition also reflects developments in nanophotonics, integrated photonics, and modern photonic device modelling. Crucially, all computational examples have been rewritten in Python, reflecting the widespread adoption of open-source scientific computing in research and education. With numerous simulation programs, exercises, and projects, the book provides students and researchers with practical tools for studying and designing photonic devices.
From its inception, America has been an unusually violent nation. In this compelling book, Elliott J. Gorn tells stories that help illuminate violence in America, how we think about it, how it changes over time, and what it means. A series of portraits in blood - eye gouging matches on the Southern frontier, the murder of the street tough Butcher Bill Poole, the rise of the crime-and-sex scandal sheet, The National Police Gazette, John Dillinger's bank robbing rampage through the Great Depression, the horrific lynching of the young Chicagoan Emmett Till, and the resurrection of his memory during the Black Lives Matter movement -Violent Men demonstrates how racism, gender, and class coalesce to paint a vivid but disturbing picture of our history.
Darwinism is not the only research tradition in evolutionary biology, but to date it is the most empirically successful. This book explores why, and why this is still true. David Depew shows how Darwinian evolutionary biology got off to a bad start by identifying natural selection with survival of the fittest -- which led to persistent misunderstandings; how it got back on track by the mid-twentieth century; and how it faced more difficulties at the turn of the twenty-first century, including challenges about how development, ecology, culture, and genetics are related. The book ends by exploring the promises and perils of genetic biotechnology. Depew's clear and accessible discussion draws on the work of evolutionary biologists, evolutionary anthropologists, historians of biology, and philosophers of biology, and the result is a compelling interdisciplinary guide to the past, present, and future of an immensely powerful concept.
Over recent years, astronomy and cosmology have made extraordinary progress in addressing and solving many fundamental problems, opening up new areas of physical enquiry. This book provides a comprehensive study of these developments, emphasising the synergies between observation and theory, from the very early Universe to the study of exoplanets. It focuses on how a vast range of physical processes and techniques may be applied to understanding current problems of modern astrophysics and cosmology. Coverage spans the whole of the electromagnetic spectrum, as well as astroparticle physics, incorporating cosmic rays, neutrino astronomy, dark matter and dark energy studies and gravitational waves. The book is written for final-year undergraduates and first-year graduate students in the physical sciences, with an appropriate level of mathematics, to help them prepare for carrying out frontier research in astrophysics and cosmology.
This clear, self-contained guide for graduate students introduces a rapidly developing area of mathematical optimization concerned with hierarchical decision-making. Starting from the basics, the book explains key theoretical ideas and shows how they lead to effective state-of-the-art algorithms for solving hierarchical decision-making problems arising in optimization, operations research, economics, engineering, and data science. The book covers mixed-integer bilevel problems and modern solution techniques such as branch-and-bound and branch-and-cut. Numerous pedagogical elements support learning, including more than 40 figures, 50 examples, over 60 exercises, and exam-style questions at the end of most chapters. With more than 220 references, the book also provides a comprehensive overview of the literature, making it a valuable entry point into this mature and increasingly important field.
This volume offers a clear and authoritative gateway into the world of Hellenistic poetry, presenting the state of the art in a form accessible to newcomers and valuable to experienced scholars alike. Designed for undergraduate and graduate students of ancient cultures, especially those in Classics, as well as instructors and researchers, it distils a complex literary era into an illuminating, concise guide. Moving beyond isolated readings of individual poets such as Callimachus, Theocritus and Apollonius, the book situates Hellenistic poetry within its rich historical, political, cultural, and religious contexts, and discusses its important afterlife in Roman poetry. It highlights how shifting power structures, expanding intellectual networks, and new forms of cultural expression and religion shaped poetic innovation both in Alexandria and in the wider Mediterranean world. Whether used in the classroom or consulted as a research companion, this Companion provides an indispensable, overview of a transformative period in ancient literature.
As water-related issues become ever more important due to a growing and migrating population, geopolitics, climate change, and changes in land use, courses on water engineering – and open channel hydraulics in particular – are only set to expand. This modern textbook includes discussions of up-to-date technology and engineering, as well as examples and exercises based on real-life problems to aid student understanding. The book provides a thorough exposition of both the theoretical treatment and contemporaneous software applications relevant to one- and two-dimensional unsteady state flow problems. In addition, there is a detailed presentation of hydraulic design procedures for open channels and water control structures. This book will be valuable for advanced undergraduate and graduate courses in civil, environmental, and agricultural engineering. It will also be used as a reference textbook for professionals in water resources engineering and management, and for practical applications of physics of open channel flows.
An accessible and streamlined foundation textbook for undergraduate atmospheric science students, Essentials of Atmospheric Science provides a comprehensive but concise introduction to weather, climate, and key atmospheric processes. Opening with a timely discussion of climate change and weather extremes, the text reflects the evolving nature of atmospheric science and has evolved from the author's two decades of teaching at the undergraduate level. A distinctive feature of the book is a dedicated chapter on essential mathematics, addressing the gap many students face when transitioning to more advanced study of topics such as atmospheric thermodynamics, dynamics, cloud microphysics, radiative transfer, and numerical weather prediction. Clear explanations, full-color figures, focus boxes, review questions, and quantitative exercises reinforce learning.