Skip to main content Accessibility help

We use cookies to distinguish you from other users and to provide you with a better experience on our websites. Close this message to accept cookies or find out how to manage your cookie settings.

Close cookie message
×
Hostname: page-component-cb9f654ff-65tv2 Total loading time: 0 Render date: 2025-08-05T16:07:03.824Z Has data issue: false hasContentIssue false

Chapter 22 - Cerebellum: Development of the Rhombic Lip, Cerebellar Cortex, Dentate Nucleus

from Neuroanatomic Site Development

Published online by Cambridge University Press:  07 August 2021

Mirna Lechpammer ,
Marc Del Bigio  and
Rebecca Folkerth
By
Rebecca Folkerth
Mirna Lechpammer
Affiliation:
New York University School of Medicine
Marc Del Bigio
Affiliation:
University of Manitoba, Canada
Rebecca Folkerth
Affiliation:
New York University School of Medicine
Get access

Summary

The cerebellum has a growth program sharing some features with, but differing importantly in tempo and sequence from, that of the cerebrum. This chapter provides a brief overview; select details of the molecular genetic mechanisms underlying human cerebellar development are discussed here, and when relevant to human malformations are further highlighted in Chapter 40.

Information

Type
Chapter
Information
Perinatal Neuropathology , pp. 107 - 110
Publisher: Cambridge University Press
Print publication year: 2021

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

Book purchase

Temporarily unavailable

References

ten-Donkelaar, HJ, Lammens, M. Development of the human cerebellum and its disorders. Clin Perinatol 2009;36:513–30.Google Scholar
Millen, KJ, Gleeson, JG. Cerebellar development and disease. Curr Opin Neurobiol 2008;18:12–19.CrossRefGoogle ScholarPubMed
Butts, T, Green, MJ, Wingate, RJT. Development of the cerebellum: simple steps to make a ‘little brain’. Development 2014;141:4031–41.CrossRefGoogle ScholarPubMed
Marzban, H, Del Bigio, MR, Alizadeh, J, Ghavami, S, Zachariah, RM, Rastegar, M. Cellular commitment in the developing cerebellum. Front Cell Neurosci 2015;8:1–26.CrossRefGoogle ScholarPubMed
Fink, AJ, Englund, C, Daza, RA, Pham, D, Lau, C, Nivison, M, Kowalcyk, T, Hevner, RF. Development of the deep cerebellar nuclei: transcription factors and cell migration from the rhombic lip. J Neurosci 2006;26:3066–76.CrossRefGoogle ScholarPubMed
Leung, AW, Li, JYH. The molecular pathway regulating Bergmann glia and folia generation in the cerebellum. Cerebellum 2018;17:42–8.CrossRefGoogle ScholarPubMed
Volpe, JJ. Cerebellum of the premature infant: Rapidly developing, vulnerable, clinically important. J Child Neurol 2009;24:1085–104.Google Scholar
Friede, RL. Developmental Neuropathology, 2nd ed. Switzerland: Springer, 1989, pp. 12–14.CrossRefGoogle Scholar

Accessibility standard: Unknown

Accessibility compliance for the PDF of this book is currently unknown and may be updated in the future.

Save book to Kindle

To save this book to your Kindle, first ensure no-reply@cambridge.org is added to your Approved Personal Document E-mail List under your Personal Document Settings on the Manage Your Content and Devices page of your Amazon account. Then enter the ‘name’ part of your Kindle email address below. Find out more about saving to your Kindle.

Note you can select to save to either the @free.kindle.com or @kindle.com variations. ‘@free.kindle.com’ emails are free but can only be saved to your device when it is connected to wi-fi. ‘@kindle.com’ emails can be delivered even when you are not connected to wi-fi, but note that service fees apply.

Find out more about the Kindle Personal Document Service.

Available formats
×

Save book to Dropbox

To save content items to your account, please confirm that you agree to abide by our usage policies. If this is the first time you use this feature, you will be asked to authorise Cambridge Core to connect with your account. Find out more about saving content to Dropbox.

Available formats
×

Save book to Google Drive

To save content items to your account, please confirm that you agree to abide by our usage policies. If this is the first time you use this feature, you will be asked to authorise Cambridge Core to connect with your account. Find out more about saving content to Google Drive.

Available formats
×