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Accurate assessment of an individual’s diet is vital to study the effect of diet on health. Image-based methods, which use images as input, may improve the reliability of dietary assessment. We developed an iOS application that uses computer vision to identify food from images. This study aimed to assess the accuracy of energy intake (EIapp) estimates from the application by comparing them to estimated energy expenditure (EE) and to the EI estimates from a validated dietary assessment tool, the 24-h recall (EIrecall). Participants were recruited from a randomised controlled trial called He Rourou Whai Painga. Participants recorded all intake over 7 d using the application, which provided a mean daily EI; this was compared to the EI estimated by two 24-h recalls. The EI from the application and the recalls were compared to EE, estimated using indirect calorimetry and wrist-worn accelerometry. EI estimates from the application and the 24-h recalls were lower than EE, with a mean bias of -1814 kJ (95% CI -3012 to -615, p = 0.005) and -1715 kJ (95% CI -3237 to -193, p = 0.029), respectively. The mean bias between EI from the application and the 24-h recall was 783 kJ (95% CI -875 to 2441, p = 0.33). This suggests that the EI estimates from the application are comparable to the 24-h recall method, a validated and widely used tool in nutritional research.
Dietary fibre can modify colostrum and milk composition in sows. Bile acids (BA) aid in fat digestion and lipid absorption and are important signalling molecules for the digestive tract. The aim of this study was to determine BA concentration in colostrum from sows fed two different sources of dietary fibre during gestation and lactation and from the intestinal digesta of their 4-6-days-old suckling offspring. Twenty sows were fed diets enriched with either 15% high-fermentable sugar beet pulp (SBP, n = 10) or 15% low-fermentable lignocellulose (LNC, n = 10). Sow colostrum, piglet gallbladder content, ileum and colon digesta were assessed for BA using high-performance liquid chromatography coupled to triple-quadrupole mass spectrometry. In colostrum, lithocholic acid and oxolithocholic acid were higher in sows fed SBP vs. LNC (p = 0.005 and p = 0.003, respectively), while 3α,7α,12α-trihydroxycholestanoic acid and glycohyodeoxycholic acid were higher in colostrum from sows fed LNC vs. SBP (p = 0.039, p = 0.002, respectively). In the piglet bile, cholic acid and taurodeoxycholic acid were higher in SBP vs. LNC group (p = 0.02, p = 0.001, respectively), while taurochenodeoxycholic acid was higher in LNC vs. SBP group (p = 0.035). In the piglet ileum digesta, lithocholic acid was higher in SBP vs. LNC (p = 0.015). In the piglet colon digesta, lithocholic acid and ursodeoxycholic acid were higher in SBP vs. LNC (p = 0.001 and p = 0.007, respectively). Addition of specific dietary fibres to sow diets differentially influences the BA in colostrum. Dietary fibres in sow diets can impact on the intestinal BA composition in piglets with a possible consequence on the digestive physiology and health in the offspring.
Ultra-processed foods (UPF) are often energy dense and low in nutrients. High consumption of UPF has been associated with non-communicable diseases, premature mortality and environmental impacts. The objective of this study was to assess UPF consumption in relation to diet quality and associated greenhouse gas (GHG) emissions, previously not examined in Iceland. Data from the Icelandic National Dietary Survey (2019–2021, n 822) were utilised. The NOVA classification system was used classifying all food and drinks reported. Dietary GHG emissions were quantified using an open-source life cycle assessment database. On average, 45 %±15 of the total calories consumed daily were derived from UPF, ranging from 24 % in the lowest quartile (UPFQ1) to 64 % in the highest quartile (UPFQ4). The energy contribution of UPF considered to fall within the Icelandic dietary guidelines was 4 %±4. UPFQ4 had significantly lower consumption of, e.g. red meat, fruits, vegetables and whole grains and higher consumption of, e.g. refined grains, sweets and soft drinks, compared with UPFQ1. UPFQ4 had a significantly higher energy intake, added sugar intake and lower intake of, e.g. proteins and iodine. The median (interquartile range (IQR)) share of dietary GHG emissions was 21 % (IQR: 11–34) of total kg CO2-eq/d, while significantly lower in UPFQ4 compared with UPFQ1. Almost half of the daily energy intake of Icelandic diets was derived from UPF, reflecting relatively poor diet quality. However, dietary GHG emissions were relatively low in high consumers of UPF, reflecting higher meat consumption in low consumers of UPF. Findings underline the urgency of policy implementation, aligning food consumption with dietary guidelines.
The multilevel dimensions of sustainable diets associating food systems, public health, environmental sustainability, and culture are presented in this paper. It begins by defining sustainable diets as those that are healthful, have low environmental impacts, are affordable, and culturally acceptable. The discussion includes the history of research on sustainable diets, from initial studies focused on environmental impacts to more recent, comprehensive frameworks that integrate affordability, cultural relevance, and nutritional adequacy as key dimensions of diet sustainability. In addition, the paper highlights recent innovations, such as the Planetary Health Diet of EAT–Lancet and the SHARP model, and the conflicts and optimum trade-offs between sustainability and nutrition, particularly within low- and middle-income countries. Case descriptions of Mediterranean Diet with a focus on Traditional Lebanese Diet, and African Indigenous Foods demonstrate culturally confined dietary patterns associated with sustainability objectives. These examples show that sustainable diets are not a single set of prescriptions, but a series of multiple pathways that are shaped by local food environments, ecological belts, and sociocultural heritages. The paper also describes major policy and governance activities necessary to promote sustainable diets. Finally, the paper addresses measurement challenges and advocates for better indicator options to measure sustainable food systems in all their facets and for participatory and context-specific approaches. The discussion concludes that fairer and culturally diverse inclusion strategies, system change, and political determination are imperative in achieving sustainable diets. Diets able to sustain are posited as agents capable of driving the 2030 agenda, enhancing planetary health and social integrity.
According to the principles of the European Pillar of Social Rights, everyone should be entitled to an adequate minimum income sufficient for a healthy diet. Studies show that food insecurity remains a concern in Europe, highlighting the need to determine budgets for adequate nutrition, known as Food Reference Budgets. Previous approaches, based on expert-designed Food Baskets or focus group discussions, are often limited by their normative nature and/or low representativeness.
Design:
To address these problems, this study explores Linear Programming as a novel method to calculate Food Reference Budgets for 26 EU member states. To analyse if Linear Programming could be an adequate tool to calculate future Food Reference Budgets, this method was used to design country-specific food baskets that align with consumption habits and healthy diet requirements. The food baskets were then priced at different levels to determine the cost for healthy diets in 26 European Countries.
Setting:
Germany
Participants:
/
Results:
The results show a positive correlation between optimised healthy and current observed diets for most food groups, indicating that country-specific preferences are reflected in the optimised healthy food baskets. Nevertheless, to meet healthy diet requirements, consumption of vegetables, fruit, fish, and dairy must increase compared to the current observed diets.
At a lower price level, the Food Reference Budgets ranged from 2.38 to 5.71 €/day, depending on the country. With a low-price level (20th percentile), costs for healthy diet accounted for between 5.74 % of income in Luxembourg and 29.00 % in Romania, showing the large differences in affordability between countries.
Conclusion:
Overall, it was concluded that Linear Programming could be a promising approach for determining uniform and comparable European Food Reference Budgets and should be discussed in the context of the EU Commission’s efforts to modernise the European minimum income schemes.
A major driver of the link between poor water, sanitation and hygiene (WASH) and child stunting is hypothesised to be a sub-clinical condition of the small intestine termed environmental enteric dysfunction (EED). This systematic review aimed to collate research investigating the association between biomarkers of EED and child linear growth outcomes. A systematic search of literature was conducted to identify articles that contain a measure of a domain of EED and its association with linear growth outcomes published up to 31 December 2024. Data pertaining to the measure of EED and child linear growth, as well as study characteristics, were extracted and tabulated. A total of eighty-one studies comprising 31 996 children were included, which suggested that all EED domains, including intestinal damage and repair, intestinal absorption and permeability, microbial translocation, intestinal inflammation and systemic inflammation, were associated with child linear growth. Nuances in the measurement of association were apparent and impacted the observation of significant associations. This review found that whilst the role of EED in child stunting is relatively well established, there are challenges faced in measuring biomarkers in relation to linear growth with possible ambiguities. These issues are discussed in detail to provide aid in interpretation of existing studies and to inform future studies of this kind.
The Mediterranean Diet (Med Diet) has long been shown to be associated with lower cardiovascular mortality in epidemiological studies. However, the direct effect of the dietary pattern on cardiovascular risk factors is less clear. Furthermore, the effect of Med Diet interventions in non-Mediterranean populations on cardiovascular and metabolic risk is variable. A Cochrane Review in 2019 concluded there was low to moderate evidence of a modest benefit but noted that there were still ongoing trials. Since 2019, there have been a number of published trials that have not shown a benefit of the Med Diet over other interventions or usual care. It is possible that dietary factors such as quality or quantity of carbohydrate and energy restriction are more important factors, along with the degree of weight loss, than the Med Diet itself. There are also many other factors that influence the uptake and effectiveness of the Med Diet in populations that have a different traditional or habitual diet. This review paper examines a selection of 20 Med Diet intervention trials specifically looking at clinical outcomes of glucose metabolism: fasting plasma glucose, HbA1c, development of type 2 diabetes or need for hypoglycaemic medications, with or without other cardiometabolic risk factors. These trials are a mix of randomised controlled trials, crossover studies and cohort studies of greater than 8 weeks duration with more than 25 participants. There is heterogeneity in study designs and outcomes, making comparison difficult, but there is no clear benefit of the Med Diet presented.
Frailty is an ageing-related syndrome of physiological decline, heightening vulnerability and increasing risk of adverse health outcomes. Nutritional deficiencies, particularly in vitamins B9, B12 and D, are prevalent among the elderly owing to physiological changes and reduced food intake. Research suggests a correlation between low levels of these vitamins and an elevated risk of frailty. Vitamin B9, crucial for DNA synthesis and cell division, shows potential in frailty prevention, although evidence regarding supplementation remains inconclusive. Similarly, vitamin B12, essential for nerve function and red blood cell formation, presents conflicting findings regarding its impact on frailty prevention. Vitamin D, essential for bone health and muscle function, is linked to frailty risk, yet studies on the efficacy of supplementation yielded mixed results. The mechanisms involving these vitamins, including their roles in DNA methylation and inflammation regulation, highlight the need for further research to clarify their direct impact on frailty prevention. Maintaining optimal levels of vitamins B9, B12 and D may reduce frailty, but older individuals need a complete approach that includes proper nutrition, physical activity and other preventive measures.
Sub-Saharan Africa (SSA) is currently undergoing rapid urbanisation, a transition that is closely linked to the adoption of sedentary lifestyles and Westernised dietary habits. This shift has contributed to a substantial rise in obesity and diet-related non-communicable diseases (DR-NCDs), placing a significant strain on already burdened healthcare systems. Among the key modifiable risk factors driving this epidemiological transition are changes in dietary patterns. Western-style diets have been shown to promote inflammation and trigger metabolic and immune dysregulation, factors that underlie the development of DR-NCDs. Conversely, many Tanzanian heritage diets incorporate a diverse array of nutrient-rich foods prepared using techniques that minimise the use of oils, sweeteners and preservatives. These diets predominantly use whole grains, legumes and fruits, foods high in dietary fibre and nutraceuticals. Nutraceuticals are known to have both immunomodulatory and metabolic benefits and could potentially counteract the negative effects associated with Western-style diets. However, the limited scientific documentation of these heritage diets endangers future research into their potential health benefits. This underscores the need for targeted efforts to preserve and promote traditional dietary practices. In this review, we summarise the diversity of heritage diets from four distinct tribes in Northern Tanzania – the Maasai, Chagga, Pare and Hadzabe – who have historically exhibited low rates of DR-NCDs but are now experiencing rapid urbanisation and lifestyle changes. We briefly describe the dietary patterns of these tribes and examine the potential links between the declining usage of traditional dietary practices and the rising prevalence of DR-NCDs in Tanzania.
Declining participation by family childcare home (FCCH) providers in the Child and Adult Care Food Program (CACFP) may stem from inadequate tiered reimbursements for nutritious foods. During the COVID-19 pandemic, federal waivers temporarily eliminated tiers and increased reimbursements. We evaluated provider, sponsor and family perceptions of CACFP benefits and challenges in general and regarding the temporary removal of tiers and increased reimbursement rates.
Design:
From September 2023 to February 2024, FCCH providers, CACFP sponsors and CACFP family recipients in California participated in semi-structured interviews about CACFP benefits and challenges, perception of tiers and the COVID-19 waiver, quality of food and business viability. Thematic analysis was conducted using the immersion crystallisation method.
Setting:
Virtual interviews with California providers, sponsors and families.
Participants:
FCCH providers (n 31), CACFP sponsors (n 10) and CACFP family recipients (n 6).
Results:
Providers and sponsors reported that the higher temporary reimbursement rate positively impacted food budgets and quality. Pandemic-era facilitators of CACFP participation included the higher reimbursement rate, tier removal and a hybrid model for monitoring visits. Benefits beyond the pandemic included nutrition education and supporting child food security. Families valued CACFP for providing a variety of high-quality foods. However, barriers to CACFP participation persist, including administrative burden, inadequate reimbursements, strict regulations and the impacts of the pandemic and inflation.
Conclusions:
Increasing CACFP reimbursements while reducing other participation barriers can better support FCCH providers’ and sponsors’ participation. Supporting FCCH CACFP participation and retention can enhance access to healthy and nutritious meals for children from families with low income.
Nutrition education plays a crucial role in improving the nutritional status of pregnant women, yet evidence of its impact in low-income settings like Ethiopia is limited. This study evaluated the effectiveness of facility-based nutrition education and counseling on pregnant women’s knowledge, dietary practices, and Fe-folic acid supplement use.
Design:
A cluster randomised controlled trial was conducted in Addis Ababa, Ethiopia, involving 683 pregnant women across twenty health centres assigned to intervention or control groups. Antenatal care providers in the intervention group received training on pregnancy nutrition and counseling, while the control group continued standard care per national guidelines. A total of 683 pregnant women were enrolled during their first and second antenatal care (ANC) visits. Mixed-effects linear regression was used to evaluate outcomes.
Study setting:
The study was conducted in Addis Ababa, Ethiopia, from August to December 2017.
Participants:
Pregnant women attending ANC follow-ups and healthcare providers working in ANC units.
Results:
The intervention group demonstrated significant improvements in knowledge, including iodised salt use (difference-in-differences (DID) 23 %), correct Fe-folic acid supplementation duration (DID 68 %) and the need for additional meals during pregnancy (DID 49·9 %). Dietary practices improved with higher dietary diversity (DID 32·3 %), increased dairy consumption (MD 1·2 v. –0·1; DID 1·2 per week) and higher Fe-folic acid supplementation (MD 4·9 v. 1·6; DID 3·2 per week).
Conclusion:
Nutrition education and counseling during ANC visits significantly improved pregnant women’s knowledge and dietary practices. Integrating and strengthening these interventions into routine ANC services could effectively enhance dietary intake and health outcomes.
Nutritional status has been compromised by ongoing war and restrictions on food deliveries in the Gaza Strip. We developed a mathematical model that outputs retrospective estimates and scenario-based projections of acute malnutrition prevalence among children given caloric intake and other factors. We present here the model and its application to the crisis in Gaza. We extended an existing mechanistic model for weight change as a function of energy balance, calibrating it to represent variability in growth curves observed in pre-war Gaza. We simulated open cohorts of children exposed to time-varying caloric intake, infant exclusive breast-feeding prevalence, incidence of infectious disease and coverage of malnutrition treatment, while allowing for adult caloric sacrifice to supplement child intake in times of food scarcity. The model accurately replicates growth standards, pre-war growth patterns and expected parameter dependencies. It suggests that a considerable increase in acute malnutrition occurred in northern Gaza during early 2024. Projections for late 2024 include a serious nutritional emergency if relatively pessimistic assumptions are made about food availability. The model may hold considerable promise for informing decisions in humanitarian response but requires further validation and development.
The first year of life is a critical period when nutrient intakes can affect long-term health outcomes. Although household food insecurity may result in inadequate nutrient intakes or a higher risk of obesity, no studies have comprehensively assessed nutrient intakes of infants from food insecure households. This study aimed to investigate how infant nutrient intakes and BMI differ by household food security.
Design:
Cross-sectional analysis of the First Foods New Zealand study of infants aged 7–10 months. Two 24-h diet recalls assessed nutrient intakes. ‘Usual’ intakes were calculated using the multiple source method. BMI z-scores were calculated using WHO Child Growth Standards.
Setting:
Dunedin and Auckland, New Zealand.
Participants:
Households with infants (n 604) classified as: severely food insecure, moderately food insecure or food secure.
Results:
Nutrient intakes of food insecure and food secure infants were similar, aside from slightly higher free and added sugars intakes in food insecure infants. Energy intakes were adequate, and intakes of most nutrients investigated were likely to be adequate. Severely food insecure infants had a higher mean BMI z-score than food secure infants, although no significant differences in weight categories (underweight, healthy weight and overweight) were observed between groups.
Conclusions:
Household food insecurity, in the short term, does not appear to adversely impact the nutrient intakes and weight status of infants. However, mothers may be protecting their infants from potential nutritional impacts of food insecurity. Future research should investigate how food insecurity affects nutrient intakes of the entire household.
This paper examines associations between maternal exposure to a radio programme, Bhanchhin Aama (Mother Knows Best), and the programme’s most promoted maternal and child nutrition-related practices, using the Nepal Demographic and Health Survey (NDHS) from 2022. We limited our sample to mothers of children less than 2 years (n = 1,933). The primary exposure variable was whether the mother listened to the Bhanchhin Aama radio programme. The five primary outcomes were: maternal dietary diversity, maternal use of modern family planning methods, exclusive breastfeeding (EBF) of children less than 6 months, dietary diversity among children 6 to 24 months, and participation in growth monitoring and promotion among children 0 to 24 months. Descriptive analyses followed by logistic regression models, adjusted for potentially confounding factors and clustering, were conducted. Maternal exposure to Bhanchhin Aama was associated with nearly 70% higher odds of meeting both maternal (OR: 1.67; p: <0.001; CI: 1.26–2.21) and child minimum dietary diversity (OR: 1.70; p: 0.005; CI: 1.18–2.45), as well as 83% higher odds of a child participating in growth monitoring and promotion (OR: 1.83; p: 0.001; CI: 1.28–2.63). No associations were found for use of modern family planning methods and EBF. These findings suggests that radio programmes may be an effective tool to improve some maternal and child nutrition-related practices. Further research is needed to understand why certain behaviours are modifiable from this type of intervention versus others that are not and for which population groups this intervention would be most effective.
Food insecurity is a global issue. The objective is to summarise the literature identifying the main outcomes related to out-of-school hours interventions that provide food for low-income families with school-aged children, how they impact school-aged children and their families, and to identify gaps in knowledge. This review covered the main types and dimensions proposed in the literature. One author independently selected the studies, and an independent reviewer randomly reviewed them. Any paper meeting the inclusion criteria was considered regardless of geographical location. Papers were predominantly from the US, UK and Australia, including school-aged children from low-income families. Ninety-four articles were included relating to holiday clubs (n = 38), breakfast clubs (n = 45) and after-school clubs (n = 11). Key outcomes were healthy eating, academic, social, physical activity, nutritional education and financial outcomes. Clubs were consistent regarding the positive social and financial outcomes. There was variation in the primary aim, either to improve healthy eating or to feed children, regardless of nutritional quality. None of the studies reported children’s health outcomes. This review identified the key outcomes of interventions for low-income families outside of school hours in the literature. It highlights the consistent positive social outcomes across the three intervention types and the discrepancy in the nutritional value of the food provided. Few studies examined the attainment impact of holiday clubs, with no evidence on how they could impact term-time attendance. This highlights the need to analyse secondary data to understand further the attainment and attendance impact on children attending these interventions over time.
Recently, functional foods have been considered as an effective approach in management of type 2 diabetes mellitus. This trial aimed to evaluate the potential benefits of date seed powder (DSP) on inflammation anxiety- and depression-like behaviours, sleep quality and tryptophan (TRP)–kynurenine (KYN) metabolism in type 2 diabetes mellitus patients. In this trial, forty-three patients with type 2 diabetes were randomised to two groups: either 5 g/d of the DSP or placebo for 8 weeks. Depression, anxiety and stress scale, sleep quality, quality of life (QoL), levels of fasting blood glucose, endotoxin, anti-inflammatory/pro-inflammatory biomarkers, hypothalamus–pituitary–adrenal (HPA) axis-associated biomarkers (including brain-derived neurotrophic factor (BDNF)), KYN, TRP, cortisol and adrenocorticotropic hormone (ACTH) were assessed at baseline and after 8 weeks. An independent t test was used for baseline comparisons, while ANCOVA was used for post-intervention between-group comparisons. The results showed that supplementation with DSP significantly improved depression, anxiety and stress scale, sleep quality and QoL in comparison with placebo. In terms of biochemical parameters, the intervention group exhibited significantly reduced levels of endotoxin, and cortisol, KYN, KYN:TRP ratio as well as significantly elevated levels of IL-10, TRP concentrations and IL-10:IL-18 ratio compared to the placebo group. Changes in fasting sugar, C-reactive protein (hs-CRP), IL-18, ACTH, BDNF concentrations and cortisol:ACTH ratio were not different between groups. Supplementing with date seed may effectively improve anxiety- and depression-like behaviours, sleep quality and QoL by modulating metabolic endotoxemia, inflammation and HPA axis activity in patients with type 2 diabetes.
Breast cancer is one of the most frequently diagnosed cancers worldwide. Although chemotherapy remains a prevalent treatment, it negatively affects patients’ quality of life. In this regard, probiotics emerge as possible adjuvants. The aim of this study was to evaluate two lactic acid bacteria (LAB) selected for their immunomodulatory properties, Streptococcus thermophilus CRL807 and Lactobacillus delbrueckii subsp. bulgaricus CRL864, in a breast cancer model undergoing chemotherapy with capecitabine or 5-fluorouracil (5-FU). 4T1 breast cancer cells were injected into the upper mammary gland of adult female mice. After tumour reached an appropriate size, mice were separated into groups (n 10) receiving either individual LAB (100 µl of 9 ± 1 × 108 CFU/ml) or yoghurt (2 ± 1108 CFU/ml ad libitum) with or without chemotherapy. The results showed that administration of LAB or yoghurt resulted in a significant reduction in tumour size and weight (about 50%), modulating the immune response, with increases of IL-10 in mice with smaller tumours, and without affecting chemotherapy. Furthermore, consumption of LAB or yoghurt decreased the negative side effects associated with these treatments. Yoghurt showed the best results in preventing weight loss, with lower mortality (20 % v. 40 % for 5-FU treatment), maintaining intestinal histology and modulating plasma cytokines, with increases of IL-10. In conclusion, administration of this probiotic yoghurt was safe in cancer hosts undergoing chemotherapy, reducing some associated negative side effects without interfering with the primary cancer treatment. Furthermore, this yoghurt showed beneficial properties against the tumour, modulating the host’s immune response.