The motivation of this article is to introduce a kind of orbit equivalence relations which can well describe structures and properties of Polish groups from the perspective of Borel reducibility. Given a Polish group G, let
$E(G)$ be the right coset equivalence relation
$G^\omega /c(G)$, where
$c(G)$ is the group of all convergent sequences in G. Let G be a Polish group. (1) G is a discrete countable group containing at least two elements iff
$E(G)\sim _BE_0$; (2) if G is TSI uncountable non-Archimedean, then
$E(G)\sim _BE_0^\omega $; (3) G is non-Archimedean iff
$E(G)\le _B=^+$; (4) if H is a CLI Polish group but G is not, then
$E(G)\not \le _BE(H)$; and (5) if H is a non-Archimedean Polish group but G is not, then
$E(G)\not \le _BE(H)$. The notion of
$\alpha $-l.m.-unbalanced Polish group for
$\alpha <\omega _1$ is introduced. Let G and H be Polish groups,
$0<\alpha <\omega _1$. If G is
$\alpha $-l.m.-unbalanced but H is not, then
$E(G)\not \le _B E(H)$. For TSI Polish groups, the existence of Borel reduction is transformed into the existence of a well-behaved continuous mapping between topological groups. As its applications, for any Polish group G, let
$G_0$ be the connected component of the identity element
$1_G$. Let G and H be two separable TSI Lie groups. If
$E(G)\le _BE(H)$, then there exists a continuous locally injective map
$S:G_0\to H_0$. Moreover, if
$G_0$ and
$H_0$ are abelian, S is a group homomorphism. In particular, for
$c_0,e_0,c_1,e_1\in {\mathbb {N}}$,
$E({\mathbb {R}}^{c_0}\times {\mathbb {T}}^{e_0})\le _BE({\mathbb {R}}^{c_1}\times {\mathbb {T}}^{e_1})$ iff
$e_0\le e_1$ and
$c_0+e_0\le c_1+e_1$.