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While clinical research on psychedelics often reports mild and transient side effects, broader survey studies indicate that a subset of users experiences lasting adverse mental health effects. This study investigated whether some of these meet diagnostic criteria for post-traumatic stress disorder (PTSD).
Methods
A cross-sectional online survey (N = 243) was conducted with individuals reporting distressing psychedelic experiences with effects persisting beyond the acute phase (convenience sampling). It assessed characteristics of the acute experience, post-traumatic stress, post-traumatic growth, and coping strategies.
Results
A total of 31.3% of participants met the DSM-5 criteria for PTSD as measured by self-report measures. PTSD symptom severity was strongly associated with characteristics of the acute experience. Avoidance-related experiences significantly predicted greater PTSD symptoms, while acceptance-related experiences were linked to lower symptom severity. Post-traumatic growth was unrelated to the intensity of the challenging experience or avoidance but positively predicted by acceptance-related experiences. Post-psychedelic help-seeking behavior was common: most consulted online resources or spoke with friends and family, though psychotherapy was rated the most helpful intervention.
Discussion
Findings provide the first systematic evidence that difficult psychedelic experiences can be associated with later PTSD symptoms and highlight the critical role of acute psychological processes in shaping long-term outcomes. Since the survey targeted individuals with highly challenging acute experiences, the data do not allow the extrapolation of prevalence estimates to the broader population of psychedelic users. As psychedelic use expands beyond clinical settings, access to trauma-informed care and targeted integration support will be essential to minimize harm and support recovery.
Researchers have revealed that the incidence of aspiration pneumonia (AP) increases following a disaster, not only due to the disaster itself but also due to environmental factors, which will propose dysphagia rehabilitation targets. We aimed to delineate the current status of dysphagia rehabilitation in disasters.
Methods
English literature was searched via scientific databases, representative journal homepages, trial registries, and gray literature.
Results
A total of 242 articles were reviewed in full text, and 31 were included in this review. Most hazards were earthquakes (19/31), and most reports originated from Japan (19/31). The reported issues were summarized according to the International Classification of Functioning, Disability, and Health (ICF) codes. Twenty-seven codes related to areas such as Swallowing, Caring for teeth, and Food were the most frequently reported. In addition, three additional items not formally listed in the ICF were considered: nutrition, oral hygiene, and denture.
Conclusions
The mechanisms of emergency lifestyle-related aspiration pneumonia were identified, and approaches to prevent AP were proposed. We further discuss how to promote dysphagia rehabilitation in disasters. Nevertheless, multidisciplinary coordination is important, and more involvement of rehabilitation specialists is required.
Contributions to this forum underscore the fact that mass migration during the Progressive Era coincided with the emergence of mass consumption. Progressive Era immigration studies are at the core of the emergent knowledge economy of the age of abundance, centered on an American standard of living that was associated with high wages, affordable goods, more leisure time, and opportunities for material and cultural self-realization. The taxonomies created during the transition to consumer capitalism frequently pathologized immigrants. In their classifications, many Progressive Era protagonists associated immigrants with a low standard of living that manifested itself in unhygienic lifestyles, unhealthy nutrition, and inappropriate consumption. In this reading, categories such as race and ethnicity are part of the construction of the figure of the consumer and the politics of consumption; they reflect modern consumerist subjectivities and structures.
This study examined the impact of maternal undernutrition during gestation and/or lactation on neonatal immune indices. From day 10 of gestation to term, pregnant rats received either ad libitum (AdLib) feeding or 50% food restriction (FR). After birth, pups were either nursed by their own dams or cross-fostered, resulting in three groups (n = 6 per group): a control group with AdLib feeding throughout (AdLib/AdLib), a group with FR only during gestation (FR/AdLib), and a group with FR during both gestation and lactation (FR/FR). At day of life 1 and at three weeks of age, spleen and thymus weights, as well as basal and lipopolysaccharide (LPS)-stimulated TNF levels and white blood cell indices, were measured in male offspring. At day of life 1, immunological indices were similar among groups. By three weeks, monocyte percentage was significantly decreased in FR/FR compared with AdLib/AdLib (1.6 ± 0.5% vs. 3.1 ± 0.4%). Relative spleen weight (adjusted for body weight) was also significantly lower in FR/FR compared with both AdLib/AdLib and FR/AdLib. Following LPS administration, TNF-α levels were reduced in FR/FR compared with FR/AdLib and AdLib/AdLib (206 ± 28 vs. 511 ± 91 and 484 ± 59 pg/ml, respectively; P < 0.05). Moreover, in FR/FR offspring, monocyte (5.4 ± 1.1% vs. 2.0 ± 0.6% and 2.0 ± 0.7%) and neutrophil (50.6 ± 5.5% vs. 17.2 ± 2.4% and 20.0 ± 4.2%) percentages were significantly increased, while lymphocyte percentage (43.2 ± 5.9% vs. 80.0 ± 2.4% and 77.2 ± 4.4%) was decreased compared with FR/AdLib and AdLib/AdLib. These findings suggest that undernutrition during both prenatal and postnatal periods can attenuate neonatal immunity by decreasing basal monocyte counts and impairing cytokine responses.
To examine mediators and modifiable psychosocial factors associated with psychological distress, depression, anxiety and self-rated health among Aboriginal and Torres Strait Islander peoples (hereafter respectfully referred to as ‘Indigenous Australians’) aged ≥18 years.
Methods
This was a cross-sectional study based on the analysis of the 2018–19 National Aboriginal and Torres Strait Islander Health Survey dataset (N = 3942). Odds ratios (OR) and 95% confidence intervals (CI) for associations and indirect effects for mediation analyses were computed.
Results
Our results showed that Indigenous Australians with higher levels of perceived social support were less likely to have psychological distress (OR = 0.36, 95% CI: 0.23, 0.56), depression (OR = 0.44, 95% CI: 0.29, 0.67), anxiety (OR = 0.43, 95% CI: 0.28, 0.65) and low self-rated health (OR = 0.52, 95% CI: 0.33, 0.82). Similarly, those with a high level of mastery were less likely to have psychological distress (OR = 0.14, 95% CI: 0.11, 0.19), depression (OR = 0.20, 95% CI: 0.15, 0.28), anxiety (OR = 0.26, 95% CI: 0.20, 0.36), and low self-rated health (OR = 0.37, 95% CI: 0.28, 0.50). Perceived social support mediated 33.7% of the association between removal from the natural family and psychological distress, 14.6% of the association between discrimination and psychological distress, 20.3% of the association between discrimination and depression, 14.8% of the association between discrimination and anxiety and 16.6% of the association between discrimination and low self-rated health. Both perceived social support and mastery mediated the association between physical harm and psychological distress, depression and anxiety.
Conclusions
We believe that community-driven psychosocial programs that enhance social support, self-efficacy and cultural connection may significantly improve the mental health and psychosocial well-being of Indigenous Australians.
The hydrodynamic interactions involved in the self-organisation phenomenon in biological systems are not fully understood and have attracted significant attention. A previous study (Peng et al. 2018 J. Fluid Mech., vol. 853, pp. 587–600) found that, arranged in an unbounded fluid, the largest cluster of self-propelled bodies in tandem, capable of spontaneously forming an ordered configuration, consists of eight swimmers. Here, we numerically investigate the collective behaviour of multiple self-propelled plates in tandem within a channel of width $H$, confined by two parallel walls. These plates are driven by harmonic flapping motions of uniform frequency and amplitude. Results demonstrate for the first time that the channel confinement significantly enhances group cohesion, with up to 72 individuals self-organising into ordered configurations at an optimal channel width. We observe two stable configurations: a hybrid mode with subgroups (typically at smaller channel widths) and a regular mode with sparse configuration. In large regular-mode groups, the vortex fields downstream exhibit spatial periodicity, conforming to Rosenhead’s stability criterion for confined vortex streets (vortex spacing $L_{v\textit{or}} \geqslant 1.419H$). This theoretical alignment explains both the observed upper channel-width limit ($H \approx 4.0{-}4.5$) for large-scale cohesion and the robust order in the regular mode. The plates may adopt spontaneously a ‘vortex-slalom’ path, reducing the drag force and energy consumption while maximising stability. Deviation from this path results in a spring-like restoring force, promptly returning the plate to equilibrium.
How does majority party security shape reciprocal bipartisan collaboration and influence legislative success? US state legislatures vary widely in the stability of majority control, offering a valuable opportunity to examine how party security conditions the incentives for cross-party collaboration. Insecure majorities may foster reciprocity as both a behavioral norm and a strategic path to legislative advancement, while long-term one-party control can diminish the returns to bipartisan engagement. I develop a theory of selective reciprocity, arguing that majority security fundamentally restructures how legislators engage in and benefit from bipartisan collaboration. Drawing on data from 401,720 bills introduced across 43 state legislatures between 2009 and 2018, I construct novel measures of bipartisan collaboration to evaluate reciprocity. I find that minority party legislators build reputational capital by consistently cosponsoring majority party bills – but their efforts yield few legislative gains in secure majority chambers. Instead, majority legislators selectively reciprocate only on minority party initiatives unlikely to pass, preserving the appearance of cooperation while protecting their policy agenda. By contrast, in insecure chambers, bipartisan cooperation is more likely to produce substantive outcomes. Reciprocity endures but is constrained – selective in form, asymmetric in effect, and structured by the institutional advantages of majority control. These findings raise broader concerns about the marginalization of minority party legislators and the limits of representation under conditions of majority security.
This symposium brings together a group of legal scholars who participated in a research project called European Society. The project originates in a meeting of the two of us and a mutual engagement with our texts. In 2022, Loïc Azoulai published a short piece on ‘The Law of European Society’ in the Common Market Law Review. The same year, Armin von Bogdandy published a book under the title Strukturwandel des öffentlichen Rechts. Entstehung und Demokratisierung der europäischen Gesellschaft (Suhrkamp), translated in English as The Emergence of European Society through Public Law (Oxford University Press 2024). At the time of publication, we were unaware of each other’s work – evidence, perhaps, that the theme was in the air. Owing to our differences in orientation and style, we decided to set up a research group, with the aim of providing a new account of the experience of Europe in the current context, marked by disorientation and polarisation, but also widely shared calls for ‘more Europe’. Europe’s current condition and its future possibilities are deeply affected by what many have classified as ‘crises’ (financial and economic crisis, migration, rule of law, external threats), but also what some Europeans even experience as ‘catastrophes’ (climate change, digital revolution, pandemic, war). The original idea was that the concept of ‘European society’ might help to get a better picture of the Europeans’ situation as well as ideas for the future course.
Infants with single ventricle CHD commonly experience gross motor delays due to physiological and environmental factors, including increased risk for white matter injury, reduced aerobic capacity, restrictive post-operative protocols, and limited movement opportunities. These delays persist in adolescence, affecting physical and social development. This study examines a quality improvement initiative within the National Pediatric Cardiology Quality Improvement Collaborative to enhance gross motor development.
Methods:
Fifteen centres participated. Gross motor skills were assessed using the Ages and Stages Questionnaires, Third Edition, at 6 and 12 months. A key driver diagram, Plan-Do-Study-Act cycles, baseline data, and ongoing process measures were collected. Interventions were implemented, including education, therapy support, and mobilisation protocols. Control charts were used to evaluate the data.
Results:
Scores from the Ages and Stages Questionnaires indicated delays in gross motor skills at baseline, with improvement over time. Participating centres showed a centerline shift from 41% to 89% of infants achieving on-target or improved motor scores, compared with 54% to 68% of infants at non-participating centres. Establishment of customised infant developmental plans increased from 62% to 74% for participating centres and from 53% to 61% for non-participating centres. Interventions included establishing processes for consistent screening, developmental plan administration, review of prone positioning, access to therapies, and early intervention referrals.
Conclusion:
This targeted quality improvement project increased the use of inpatient practices to support gross motor development for infants with single ventricle CHD. Collaborative, interdisciplinary efforts remain critical for addressing neurodevelopmental challenges in this high-risk population.
Natural disasters may worsen cancer outcomes through treatment delays, screening interruptions, or fragmented health care delivery. We investigated whether climate-related natural disasters were associated with changes in county-level prostate-specific antigen (PSA) screening.
Methods
We modeled county-level screening estimates from the Behavioral Risk Factor Surveillance System (BRFSS) from 2004 to 2012 using Census-derived demographic weights. The Federal Emergency Management Agency (FEMA)’s Disaster Declarations Summaries database was used to include counties that experienced a single climate-related natural disaster. The year of disaster was considered the index date, with 2-year pre- and post-disaster periods used to model counterfactual screening prevalence with vs without a natural disaster. Primary outcome was county-level PSA screening prevalence. We applied log-linear regression to estimate prevalence ratios for the association between natural disaster and two-year county-level PSA screening.
Results
In 37 states, 365 counties experienced a single natural disaster, including a total population of 7,584,059 men aged 40-79. Compared to baseline county-level screening prevalence, PSA screening in the 2-year post-disaster period was 8% lower (rate ratio [RR]:0.92, 95% CI: 0.90-0.94, P <0.001]).
Conclusions
We observed significantly lower county-level PSA screening prevalence following a climate-related natural disaster. These results underscore the potential impacts of climate-related natural disasters on cancer screening services.
Magnetised liner inertial fusion (MagLIF) has attracted attention in the past decade for its high obtained Lawson triple products and prospects to scale to ignition. In this work, we investigate the effect of viscosity on the sausage instability and magneto-Rayleigh–Taylor instability (MRTI) in conditions relevant for MagLIF implosions. First, we quantify the amount of damping that viscosity has on instability growth by deriving an expression for the ratio between viscous and inviscid growth rates. This expression is parameterised by a single non-dimensional number: the Galilei number $Ga$, which measures the ratio of gravitational and viscous forces. We discuss in detail the physical intuition $Ga$ provides on instability growth. The derived growth rates are then validated against FLASH simulations. We then calculate a critical viscosity threshold $\eta _{c}$ required for viscosity to dampen the instability growth rate by 5 %. From this analysis, we show that, for drive currents relevant to laboratory MagLIF experiments (of the order of tens of MA), this critical viscosity threshold is much greater than realistic liner viscosity values except for the shortest perturbation wavelength regimes. We conclude that viscosity does not play a significant role in the initial linear growth of the sausage instability and MRTI in MagLIF liners, but our results motivate future investigation into effects of viscosity in nonlinear and high temperature regimes.
Aerococcus urinae, a gram-positive bacterium found in 0.25–4% of urinary samples, is increasingly recognised as a cause of invasive urinary tract infections and bacteraemia. Its true prevalence is likely underestimated due to misidentification as other gram-positive cocci. Advances like matrix-assisted laser desorption ionisation time-of-flight mass spectrometry have improved diagnostic accuracy. Though rare, A. urinae infective endocarditis is being reported more frequently, especially in adults with cardiac and urinary tract abnormalities. Paediatric cases are uncommon but can be severe. We report a case of mitral valve infective endocarditis in a 15-year-old female with congenital heart defects and neurogenic bladder, presenting with embolic stroke. This highlights the need for prompt diagnosis and multidisciplinary management to improve outcomes in this rare but serious condition.
In this article, we explore how Long-Term Residential Care (LTRC) features contribute to violence against staff.
Methods:
Data were collected using a mixed-methods case study in LTRC, including an online survey (N = 240) and interviews with staff (N = 29) in two Canadian provinces.
Findings:
Survey data showed 97.2% of staff reported experiencing at least one form of violence from residents, and 53.2% experienced one or more forms of violence from family carers. Severe physical violence from residents was significantly correlated with the number of different types of training staff received and working with a higher proportion of residents with cognitive impairment. Staff attributed violence from family carers to mistrust, lack of understanding, and ‘unrealistic expectations’ while they attributed violence from residents to insufficient resources.
Discussion:
Violence in LTRC occurs across multiple relationships. To address this, structural changes to staffing and working conditions that enhance trust and relational care are essential.
Violence against health workers and health care facilities in conflict settings is a major public health concern, disrupting service delivery and undermining humanitarian response. While attacks on health care have been widely documented, standardized multicountry comparisons using consistent surveillance metrics remain limited.
Methods
A retrospective, descriptive observational analysis was conducted using incident-level, open-source records curated on the United Nations Humanitarian Data Exchange (HDX) from 2016 to 2024, covering 20 conflict-affected settings. Incidents involving harm to aid and health workers and attacks on health care facilities were summarized descriptively and standardized per capita to enable cross-setting comparison.
Results
Across the 20 settings, reported harm to health systems increased after 2021. PSE exhibited the highest per-capita burden, with 407 aid and health-worker fatalities and 420 reported attacks on health care facilities, while Ukraine recorded the highest absolute number of facility attacks (1,060). Myanmar demonstrated a distinct pattern characterized by large-scale arrests of health care workers following the 2021 military coup. Other settings demonstrated variable burdens and harm modalities, including personnel-lethal, infrastructure-destructive, and coercive patterns.
Conclusions
Reported attacks on health care in conflict settings are widespread and heterogeneous. This descriptive, per-capita comparison highlights variability in harm modalities across settings and identifies high-burden contexts that may warrant prioritization for surveillance strengthening, preparedness planning, and protection-focused operational coordination. Further research is needed to examine drivers, impacts on service delivery, and prevention strategies using attribution-aware, mixed-methods approaches.
Cedric Robinson is often invoked for his account of racial capitalism forwarded in his 1983 book Black Marxism. Yet much of what Robinson meant by the term has been lost in its posthumous revival in the wake of Black Lives Matter. What accounts for this belated reception, and what has that delay obscured? Like many thinkers associated with the cultural turn, Robinson theorized racial capitalism to critique economic reductionist accounts of race and culture. Unlike his contemporaries, however, Robinson understood culture as the expression of world-historical peoplehood. Rather than an account of historical difference or the contingency of meaning, Robinson theorized culture as emergent from civilizational struggle. This article argues that Robinson’s distinctive account of culture explains both the lack of attention he generated in his own moment and its sudden canonization today.