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En 1924 y 1931, Brasil recibió la visita de misiones inglesas cuyo objetivo más evidente era diagnosticar los problemas de la economía brasileña y recomendar soluciones. Entre otras recomendaciones, ambas señalaron la necesidad de crear un banco central en el país, en consonancia con la reanudación del patrón oro en los países centrales después de la Primera Guerra Mundial y las conferencias internacionales de 1920 y 1922. Ocurre que, en Brasil, las propuestas de reforma monetaria y la creación de un banco central fueron debatidas por sucesivos gobiernos y legislaturas al menos desde el fin del Imperio. El principal objetivo de este trabajo es afirmar la existencia en el país de un extenso debate sobre el tema y diversas experiencias con bancos de emisión antes de la llegada de los money doctors.
In recent years, there has been extensive work on inequalities among partition functions. In particular, Nicolas, and independently DeSalvo–Pak, proved that the partition function $p(n)$ is eventually log-concave. Inspired by this and other results, Chern–Fu–Tang first conjectured the log-concavity of $k$-coloured partitions. Three of the authors and Tripp later proved this conjecture by introducing recursive sequences and a strict inequality for fractional partition functions, giving explicit errors. In this paper, we show that the log-concavity is, in fact, strict for $k\geq 2$. We shed further light on this phenomenon by utilizing Hardy–Littlewood–Pólya’s notion of majorizing. We prove that for partitions $\boldsymbol{a},\boldsymbol{b}$ of $n\in{\mathbb N}$, if $\boldsymbol b$ majorizes $\boldsymbol a$, then $p_k(\boldsymbol{a}) \gt p_k(\boldsymbol{b})$. Numerical calculations indicate that our result is sharp.
We perform causal analysis on the low-dimensional Galerkin model for shear flow developed by Moehlis et al. (New J. Phys., vol. 6, 2004, 56). Our method integrates both equation-based analysis and the proposed Galerkin-based Granger causality (GGC) to investigate the effect of the nonlinear terms on the dynamics. Two types of quadratic interactions are identified: a fully triadic interaction and a modulated two-mode coupling. The propagation of these interactions through the nonlinear dynamics leads to a directed cause-and-effect network. Furthermore, the relative importance of each mode amplitude on the dynamics of the target mode is quantified. This analysis provides a deeper understanding of the nonlinear dynamics and distills control opportunities. To demonstrate the applicability of the proposed GGC to realistic flows where Galerkin projection is impractical, a turbulent lid-driven cavity flow is further studied. We foresee applications of the proposed causal analysis framework as valuable tools for Galerkin modelling – guiding investigations of modal causality, prediction uncertainty, model-order reduction and control design.
Venous thromboembolism prevalence amongst paediatric patients with CHD has increased over the years. Enoxaparin’s favourable pharmacokinetic and pharmacodynamic properties, paired with less intensive monitoring parameters, make it a desirable treatment option. Currently, reported enoxaparin dosing strategies and their correlation to therapeutic anti-Xa levels are variable for infants aged 2 to 12 months.
Methods:
This retrospective chart review evaluated the percentage of patients who achieved initial target anti-Xa levels on therapeutic enoxaparin. Patients were divided into standard-dose enoxaparin of 1 mg/kg every 12 hours and high-dose enoxaparin of 1.5 mg/kg every 12 hours.
Results:
Eighty-five patients were included in this study with similar demographics. More patients in the high-dose group achieved initial therapeutic levels of enoxaparin (36 (69%) vs 5 (15%); p < 0.001). The time between initial dose of enoxaparin and first therapeutic anti-Xa level was longer in the standard-dose group (87 hrs (IQR 41 to 112) vs 24 hrs (IQR 16 to 40; p < 0.001)), and there was no difference in the incidence of minor bleeding (6 (18%) vs 4 (7.7%); p = 0.18) or major bleeding (1 (3%) vs 0 (0%); p = 0.39), respectively.
Conclusions:
High-dose enoxaparin in infants with CHD resulted in a higher percentage of initial anti-Xa target attainment and a decreased time to target anti-Xa level, with no difference in bleeding. Our study suggests it may be safe and effective to dose enoxaparin higher in infants with CHD; however, further studies should confirm these findings.
Easy, universal, and cost-effective methods of gamete preservation for echinoids are required since echinoids are important model organisms for studying fertilization and early development, and at the same time, they are valuable fishery resources, and key components of marine ecosystems. In general, cryopreservation is the common method of animal sperm preservation, but we previously reported a simple method using a chilled condition as an alternative choice, using Hemicentrotus pulcherrimus. In this study, we applied this method to various echinoid species to test whether it was effective for them, and then we determined the features of the preserved sperm in detail. The fertilization capability of preserved sperm was maintained for several weeks, though higher sperm density was needed to obtain 100% fertilization in later periods. Eggs fertilized by the preserved sperm developed normally, and the morphology of the embryos was not affected. Sperm swimming in a stable, regular manner were observed even at the end of the preservation period, though the flagellar beat frequency was substantially decreased during preservation. There was almost no change of the flagellar beat form during preservation. Here, we showed that our simple method is basically applicable to various echinoid species and provides the opportunity for effective and immediate use of competent echinoid sperm by a wide variety of users, such as people in research, fisheries and education.
Recent advances in healthcare and rising life expectancy intensify longevity risk, motivating a deeper understanding of how cause-of-death (COD) rates interact. Using male COD data from 1978 to 2018 in the United States, we develop a copula-based hierarchical framework for seven major causes: cancer, diabetes, external causes, influenza, mental disorders, nephritis, and vascular disease. The framework integrates reconciliation, hierarchical dependence, and long-run equilibrium using a Lee–Carter (LC) setting. More specifically, the LC period indices are estimated under reconciliation penalties and are modeled through a sparse vector error correction model, with dependence captured by a hierarchical Archimedean copula. Two applications illustrate the value of our approach. In out-of-sample forecasting, the framework outperforms the standard LC model by improving the accuracy of aggregate mortality rates. In structural analysis, fitted connectedness reveals that diabetes and vascular disease act as net transmitters of mortality shocks, while cancer and external causes are net receivers. These insights help actuaries, demographers, clinicians, and policymakers enhance mortality forecasting to assess whether prioritizing government interventions for high-transmission causes could potentially maximize overall mortality improvements for society.
We study a nonlinear branching diffusion process in the sense of McKean, i.e. where particles are subjected to a mean-field interaction. We consider first a strong formulation of the problem and we provide an existence and uniqueness result by using contraction arguments. Then we consider the notion of weak solution and its equivalent martingale problem formulation. In this setting, we provide a general weak existence result, as well as a propagation of chaos property, i.e. the McKean–Vlasov branching diffusion is the limit of a large-population branching diffusion process with mean-field interaction.
This study evaluated the psychometric properties of the Turkish version of the Comprehensive Emotional Eating Scale (CEES) and examined its associations with emotion regulation, cognitive control, cognitive flexibility, and perceived stress in adults. A cross-sectional design was conducted with 1,521 adults aged 18–74 (68% female). The CEES was adapted following standard cross-cultural guidelines, including translation, back-translation, and approval by the original scale developer. Participants also completed the Emotional Appetite Questionnaire (EMAQ), Difficulties in Emotion Regulation Scale (DERS-16), Cognitive Control and Flexibility Questionnaire (CCFQ), and Perceived Stress Scale (PSS). Confirmatory factor analysis (CFA) assessed construct validity, while internal consistency, convergent validity, and multiple linear regression analyses explored predictors of emotional eating. CFA supported a four-factor structure representing Undereating–Positive Emotions, Undereating–Negative Emotions, Overeating–Positive Emotions, and Overeating–Negative Emotions, with item loadings of 0.48–0.77; one item was removed due to low loading. Internal consistency was high (α = .88–.91), and convergent validity was confirmed via EMAQ correlations. Multiple regression analyses indicated that greater difficulties in emotion regulation, higher perceived stress, lower cognitive control and flexibility, smoking, higher Body Mass Index (BMI), and chronic disease significantly increased emotional eating. Women showed higher undereating-negative emotion and total emotional eating scores, while smoking, higher BMI, and chronic disease elevated scores on specific subscales. The Turkish CEES demonstrates robust psychometric properties and reliably captures multidimensional emotional eating in adults. Psychological and demographic factors increase emotional eating subscales and total scores, supporting the scale’s use in research and clinical settings in Türkiye.
Obtaining accurate estimates of children’s dietary intake is important because these estimates are used to characterize diet-disease relationships and inform nutrition interventions. This systematic review synthesized findings from validation studies of dietary assessment tools for children (aged 1-10 years), in which parents were proxy-reporters. Database searches (Ovid Medline, Embase, Web of Science, Cochrane) in January 2026 for validation studies of dietary assessment tools used for estimating daily intake of macronutrients and micronutrients yielded 4,545 citations. Articles were uploaded to Covidence for screening. Sixty-six articles met the inclusion criteria. Median sample size was 103. Eighty-six percent of studies (n=57) validated a food frequency questionnaire; the remainder validated dietary recalls (11%, n=8) or food diaries (2%, n=1). Many studies (67%, n=44) used another parent-proxy report tool as the reference method. For most nutrients, over a quarter of the 66 studies failed to find a significant correlation between the assessment tool and reference method. Among the 69% of analyses that did show a significant correlation, the median correlation for each nutrient ranged from 0.37 to 0.40 for macronutrients and 0.29 to 0.55 for micronutrients. Studies were limited by lack of generalizability, use of reference methods prone to error, and misalignment between the assessment tool and reference method. Overall, this review found no correlation or low-to-moderate correlations between dietary assessments and the reference method. The studies had significant methodological limitations. Future studies should validate parent-proxy report dietary assessments against objective measures, such as biomarkers. The development of novel assessment tools may also be warranted.
Honoring a patient’s wishes for end-of-life care can be challenging if the patient loses decision-making capacity and the identified alternate decision-maker will not respect the patient’s wishes. This article discusses how to proceed ethically and legally when the alternate decision-maker and care team disagree about respecting a patient’s end-of-life preferences.