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We study computational aspects of repulsive Gibbs point processes, which are probabilistic models of interacting particles in a finite-volume region of space. We introduce an approach for reducing a Gibbs point process to the hard-core model, a well-studied discrete spin system. Given an instance of such a point process, our reduction generates a random graph drawn from a natural geometric model. We show that the partition function of a hard-core model on graphs generated by the geometric model concentrates around the partition function of the Gibbs point process. Our reduction allows us to use a broad range of algorithms developed for the hard-core model to sample from the Gibbs point process and approximate its partition function. This is, to the extent of our knowledge, the first approach that deals with pair potentials of unbounded range.
Research on the settling dynamics of snow particles, considering their complex morphologies and real atmospheric conditions, remains scarce despite extensive simulations and laboratory studies. Our study bridges this gap through a comprehensive field investigation into the three-dimensional (3-D) snow settling dynamics under weak atmospheric turbulence, enabled by a 3-D particle tracking velocimetry (PTV) system to record over a million trajectories, coupled with a snow particle analyser for simultaneous aerodynamic property characterization of four distinct snow types (aggregates, graupels, dendrites, needles). Our findings indicate that while the terminal velocity predicted by the aerodynamic model aligns well with the PTV-measured settling velocity for graupels, significant discrepancies arise for non-spherical particles, particularly dendrites, which exhibit higher drag coefficients than predicted. Qualitative observations of the 3-D settling trajectories highlight pronounced meandering in aggregates and dendrites, in contrast to the subtler meandering observed in needles and graupels, attributable to their smaller frontal areas. This meandering in aggregates and dendrites occurs at lower frequencies compared with that of graupels. Further quantification of trajectory acceleration and curvature suggests that the meandering frequencies in aggregates and dendrites are smaller than that of morphology-induced vortex shedding of disks, likely due to their rotational inertia, and those of graupels align with the small-scale atmospheric turbulence. Moreover, our analysis of vertical acceleration along trajectories elucidates that the orientation changes in dendrites and aggregates enhance their settling velocity. Such insights into settling dynamics refine models of snow settling velocity under weak atmospheric turbulence, with broader implications for more accurately predicting ground snow accumulation.
The crystal structure of gepirone has been solved and refined using synchrotron X-ray powder diffraction data and optimized using density functional theory techniques. Gepirone crystallizes in space group P21/a (#14) with a = 16.81794(14), b = 11.71959(5), c = 10.10195(4) Å, β = 95.7012(5)°, V = 1981.239(14) Å3, and Z = 4 at 298 K. The crystal structure consists of discrete gepirone molecules. There are no classical hydrogen bonds in the crystal structure, but several intra- and intermolecular C–H⋯N and C–H⋯O hydrogen bonds contribute to the lattice energy. The powder pattern has been submitted to ICDD® for inclusion in the Powder Diffraction File™ (PDF®).
Based on the discursive analysis of 28 semidirected interviews conducted in the small industrial town of Martfű, this article reflects on the role played by nationalism in the construction of political and cultural hegemony by Viktor Orbán’s Fidesz, Hungary’s ruling party since 2010. The ten themes mobilised by the respondents to express their vision of the Hungarian nation (identification, belonging, commitment, transmission, territory, uniqueness/fragility, heterogeneity/homogeneity, unity/division, east/west, and insubordination) and the issues attached to them (relationship to Hungarian minorities of neighbouring countries, relationship to the European Union, immigration, etc.) are paralleled with Fidesz’s discourse. On those subjects, Orbán’s party’s nationalism positions itself in a “central” way, managing to incarnate heterogeneous conceptions of the nation that are shared among this research’s respondents by Fidesz as well as non-Fidesz voters.
Female crabs enter a stage of rapid ovarian development after mating, and cholesterol is a substrate for steroid hormone synthesis. Therefore, in this experiment, an 8-week feeding trial was conducted to investigate the effects of mating treatments (mated crab and unmated crab) and three dietary cholesterol levels (0·09 %, 0·79 % and 1·40 %) on ovarian development, cholesterol metabolism and steroid hormones metabolism of adult female swimming crab (Portunus trituberculatus). The results indicated that crabs fed the diet with 0·79 % cholesterol significantly increased gonadosomatic index (GSI) and vitellogenin (VTG) content than other treatments in the same mating status. Moreover, mated crabs had markedly increased GSI and VTG content in the ovary and hepatopancreas than unmated crabs. The histological observation found that exogenous vitellogenic oocytes appeared in the mated crabs, while previtellogenic oocytes and endogenous vitellogenic oocytes were the primary oocytes in unmated crabs. The transmission electron microscopy analysis showed that when fed diet with 0·79 % cholesterol, the unmated crabs contained more rough endoplasmic reticulum and mated crabs had higher yolk content than other treatments. Furthermore, mating treatment and dietary 0·79 % cholesterol level both promoted cholesterol deposition by up-regulation of the mRNA and protein expression levels of class B scavenger receptors 1 (Srb1), while stimulating the secretion of steroid hormones by up-regulation of the mRNA and protein expression of steroidogenic acute regulatory protein (Star). Overall, the present results indicated that mating behaviour plays a leading role in promoting ovarian development, and dietary 0·79 % cholesterol level can further promote ovarian development after mating.
Several psychological models of bipolar disorder propose that certain types of appraisals can lead to increases in manic symptoms.
Aims:
We tested whether the belief that being ‘high’ is a natural part of one’s personality and correlates with manic symptoms 4 months later when controlling for manic symptoms at baseline.
Method:
This was a prospective 4-month follow-up design using self-report measures. Forty people with a diagnosis of bipolar disorder completed a measure of manic symptoms, a measure of appraisals associated with bipolar disorder, and a single-item measure, ‘To what extent do you feel like being “high” is a natural part of your personality?’, at baseline and follow-up.
Results:
The single-item measure showed modest stability over time and construct validity in its correlation with a standardised measure of appraisals in bipolar disorder. As predicted, the single-item measure correlated with manic symptoms at follow-up when controlling for manic symptoms at baseline.
Conclusions:
The belief that being ‘high’ is a natural part of one’s personality is a potential predictor of manic symptoms. Further research needs to study the potential mediating mechanisms such as activating behaviours, and control for indicators of the bipolar endophenotype.
This article focuses on an alphabetically ordered collection titled The Lügat of İstanbul Fifty Years Ago, published in 1942 by the prolific Turkish historian and writer Reşad Ekrem Koçu. Despite its rich and lesser-known descriptions and stories of İstanbul’s historical spaces, people, and events in each entry with anecdotes, quotes, and comments, the Lügat has remained relatively unknown. Koçu drew on the memoirs and journalistic essays of Turkish journalist Ahmed Rasim, who vividly captured the essence of the city in his writings during the 1890s. This article examines Koçu’s endeavor to establish a methodology for urban historiography by rearranging and re-animating the depictions of the mundane urban past in a new encyclopedic genre, Lügat, while placing it within the wider framework of urban history literature in İstanbul. Through a critical analysis of the narratives portraying the perils and pleasures of İstanbul in the Lügat, this article illustrates how Koçu’s classifications are intertwined with subjective interpretations rather than rational objectifications.
We investigate the dynamics of a columnar Taylor–Green vortex array under strong stratification, focusing on Froude numbers $0.125\leq Fr \leq 1.0$, with the aim of identifying and understanding the primary instabilities that lead to the vortices’ breakdown. Linear stability analysis reveals that the fastest-growing vertical wavenumber scales with $Fr^{-1}$, while the dimensionless growth rate remains approximately constant. The most unstable eigenmode, identified as the mixed hyperbolic mode by Hattori et al. (J. Fluid Mech., vol. 909, 2021, A4), bears significant similarities to the zigzag instability, first discovered by Billant & Chomaz (J. Fluid Mech., vol. 418, 2000, pp. 167–188). Direct numerical simulations further confirm that the zigzag instability is crucial in amplifying initial random perturbations to finite amplitude, with the flow structure and modal growth rate consistent with the linear stability analysis. In particular, the characteristic vertical length scale of turbulence matches that of the fastest-growing linear mode. These findings underscore the broader relevance of the zigzag instability mechanism beyond its initial discovery in vortex pairs, demonstrating its role in facilitating direct energy transfer from vertically uniform vortical motions to a characteristic vertical length scale proportional to $Fr$ in strongly stratified flows.
The ideological and issue positions of parties are known to shape citizens’ political attitudes and voting behaviour. One important way to obtain estimates of parties’ positions is to ask experts to place parties on salient ideological dimensions. The Chapel Hill Expert Survey (CHES) has been collecting such estimates for democracies in Europe and elsewhere. CHES Canada adds to this project by providing estimates of party positions and characteristics of Canadian federal parties and provincial parties in Ontario and Quebec. This note introduces this new data source, clarifies how the data were collected and illustrates how the data can be used to (comparatively) study party politics in Canada.
As the population of Aotearoa New Zealand ages, informal family carers will play an increasingly important role in caring for older adults at home. Multi-generational living arrangements are a growing trend, particularly among Māori communities, where caring for older relatives within the family home is widespread. This article uses in-depth, semi-structured interviews with Māori whānau (extended family members) caring for kaumātua (older family members) at home to explore how carers experienced care coordination in the broader care collective. The findings centred on three interconnected factors that described the collective organisation of care: (1) whānau care as normal; (2) whānau care as collective coordination; and (3) whānau carer knowledge and needs as unseen. The findings show that although whānau care of kaumātua is highly valued, ‘structural holes’ within care systems contribute to challenges in care coordination. Despite extensive whānau support for kaumātua, primary carers often felt that their knowledge, preferences and self-care needs remained unseen and not translatable to those outside the everyday care situation. Rather than assuming an artificial binary difference between ‘collective’ and ‘individually oriented’ care contexts and cultures, analysing the cultural norms surrounding whānau care-giving confirms that collective care system members face similar and different challenges to carers with smaller caring capacities.
Gilles Deleuze est, parmi les penseurs français contemporains, celui ayant démontré la plus grande sensibilité à l’égard de la culture québécoise en intégrant quelques-unes de ses forces révolutionnaires dans son œuvre. C'est ce qu'illustre la première partie de l'article en faisant référence à des figures culturelles marquantes discutées par Deleuze : Jack Kérouac, Pierre Perrault, Michèle Lalonde, Norman McLaren et Alexis le Trotteur. L'article explore ensuite la réception de Deleuze au Québec dans et à l'extérieur des milieux universitaires en montrant que la pensée deleuzienne a pris part à la contre-culture avant d'acquérir une visibilité au sein des départements de philosophie.
Seven decades after Brown v. Board, Black students continue to lag White students. This article analyzes six experiments conducted over three decades to study whether, consistent with social identity theory, White Americans are more supportive of funding increases for nonracially targeted educational programs that benefit their racial ingroup compared to race-targeted programs. We also ask whether racial prejudice is a factor, if implicit or explicit racial priming accounts for any observed differences, and if the effects have changed over time. Our results show that consistent with social identity theory, White Americans are more likely to favor funding increases for public schools or programs for poor children, categories that are majority White, than programs targeted to Black children. Furthermore, we find no evidence of implicit or explicit racial priming. Across all experiments and all years, interactions between racial priors and the treatments are null. We conclude that ingroup favoritism, not prejudice nor racial priming, explains racially discriminatory support for increases in education funding.
Let $r$ be any positive integer. We prove that for every sufficiently large $k$ there exists a $k$-chromatic vertex-critical graph $G$ such that $\chi (G-R)=k$ for every set $R \subseteq E(G)$ with $|R|\le r$. This partially solves a problem posed by Erdős in 1985, who asked whether the above statement holds for $k \ge 4$.
In this paper, we study a connection between disintegration of measures and geometric properties of probability spaces. We prove a disintegration theorem, addressing disintegration from the perspective of an optimal transport problem. We look at the disintegration of transport plans, which are used to define and study disintegration maps. Using these objects, we study the regularity and absolute continuity of disintegration of measures. In particular, we exhibit conditions for which the disintegration map is weakly continuous and one can obtain a path of measures given by this map. We show a rigidity condition for the disintegration of measures to be given into absolutely continuous measures.
Systemic changes in multiple diseases may influence the onset of dementia. However, the specific temporality between exposure diseases and dementia remains uncertain.
Aims
By characterising the full spectrum of temporal disease trajectories before dementia, this study aims to yield a global picture of precursor diseases to dementia and to provide detailed instructions for risk management and primary prevention of dementia.
Method
Using the multicentre, community-based prospective UK Biobank, we constructed disease trajectories before dementia utilising the phenome-wide association analysis, paired directional test and association quantification. Stratified disease trajectories were constructed by dementia subtypes, gender, age of diagnosis and Apolipoprotein E (ApoE) status, respectively.
Results
Our study population comprised 434 266 participants without baseline dementia and 4638 individuals with all-cause dementia. In total, 1253 diseases were extracted as potential components of the disease trajectory before dementia. We identified three clusters of disease trajectories preceding all-cause dementia, initiated by circulatory, metabolic and respiratory diseases occurring approximately 5–15 years before dementia. Cerebral infarction or chronic renal failure following chronic ischaemic heart disease was the specific trajectory before vascular dementia. Apolipoprotein E (ApoE) ε4 non-carriers exhibited more complex trajectories compared with carriers. Lipid metabolism disorders remained in the trajectories regardless of dementia subtypes, gender, age of diagnosis and ApoE status.
Conclusions
This study provides a comprehensive view of the longitudinal disease trajectories before dementia and highlights the potential targets of midlife cardiometabolic dysfunction for dementia screening and prevention.
Several models of maternal undernutrition reveal impairment of testicular development and compromise spermatogenesis in male offspring. The expansion of the litter size model, valuable for studying the impact of undernutrition on early development, has not yet been used to evaluate the consequences of early undernutrition in the adult male reproductive system. For this purpose, pups were raised in either normal litter (ten pups/dam) or large litter (LL; sixteen pups/dam). On postnatal day 90, sexual behaviour was evaluated or blood, adipose and reproductive tissues were collected for biochemical, histological and morphological analysis. Adult LL animals were lighter and thinner than controls. They showed increased food intake, but decrease of retroperitoneal white adipose tissue weight, glycaemia after oral glucose overload and plasma concentration of cholesterol. Reproductive organ weights were not altered by undernutrition, but histopathological analysis revealed an increased number of abnormal seminiferous tubules and number of immature spermatids in the tubular lumen of LL animals. These animals also showed reduction in total spermatic reserve and daily sperm production in the testes. Undernutrition decreased the number of Sertoli cells, and testosterone production was increased in the LL group. Mitochondrial activity of spermatozoa remained unchanged between experimental groups, suggesting no significant impact on the energy-related processes associated with sperm function. All animals from both experimental groups were considered sexually competent, with no significant difference in the parameters of sexual behaviour. We conclude that neonatal undernutrition induces histological and physiological testicular changes, without altering sperm quality and sexual behaviour of animals.
For too long, questions of racism and colonialism have not been part of historical sociology’s understanding of modernity. Yet, a new generation of scholars has begun to address this, placing racism and empire at the center of their inquiries. This new generation looks to previously marginalized scholars for guidelines and inspiration. In line with this shift in historical sociology, this paper brings the work of W.E.B. Du Bois and other writers in the Black Radical Tradition to bear on longer-standing analytic and methodological debates: How do these authors allow us to think about theory-building and comparison? What is the goal of explanation? How should we approach archives and sources? Building on these insights, this paper explains how the work of Du Bois and the Black Radical Tradition provides a model for a new historical sociology, and a framework that allows us to see the connections between racism, colonialism, and modernity.