The Intergovernmental Negotiating Committee (INC) on plastic pollution are United Nations member states who will convene for the second part of the fifth session of the Intergovernmental Negotiating Committee in Geneva (INC5.2) 5-14 August, 2025 to negotiate a global plastics treaty. The Scientists’ Coalition for an Effective Plastics Treaty (‘The Scientists’ Coalition’) is an international network of independent scientific and technical experts who have been contributing robust science to treaty negotiators since INC1 in 2022. The Scientists’ Coalition established a series of working groups following INC5.1 in Busan, Korea 25 November – 1 December 2024. Each working group has produced science-based responses to the selected articles of ‘the Chair’s text’ (the latest version of the draft global plastics treaty text). This Letter to the Editor summarises those responses.

Previous studies on the association between fruit juice consumption and type 2 diabetes remain controversial, which might be due to heterogeneity in the polygenic risk score (PRS) for type 2 diabetes. We examined the association between fruit juice and type 2 diabetes by PRS for type 2 diabetes. We investigated whether fruit juice influences type 2 diabetes risk differently among individuals with varying genetic risks. Data from the Japan Multi-Institutional Collaborative Cohort (J-MICC) study, a cross-sectional study of 13 769 Japanese individuals was used for our analysis. The primary exposure was the frequency of fruit juice, categorised as do not drink, less than 1 cup per day or more than 1 cup per day. We selected PGS002379, a PRS for type 2 diabetes developed using East Asian populations. The primary outcome was physician-diagnosed type 2 diabetes, reported by participants. The consumption of fruit juice was significantly inversely associated with type 2 diabetes in the group with a high PRS for type 2 diabetes (OR: 0·78, 95 % CI: 0·65, 0·93 for < 1 cup/d and OR: 0·54, 95 % CI: 0·30, 0·96 for > 1/d), but this association was not observed in the low PRS group. Fruit juice consumption was inversely associated with type 2 diabetes, especially in genetically high-risk populations for type 2 diabetes.

The frequency responses of circulation control and separation control using mini-spoilers for loads attenuation on plunging swept and unswept wings were compared in a water tunnel study. At the pre-stall angle-of-attack, the effectiveness of the spoilers significantly diminishes with increasing reduced frequency of the plunging motion. For the leading-edge spoiler, this happens because the roll-up of the vorticity promotes flow reattachment and reduces the effectiveness of loads attenuation. For the trailing-edge spoiler, the effectiveness of lift attenuation also decreases with increasing reduced frequency, due to the shedding of leading-edge vortices and immersion of the trailing-edge spoiler in the separated flow. The decay of the frequency response for both types of spoilers is similar, implying that it is dictated by the flow separation near the leading edge of the wing in both cases. With increasing sweep angle of the wings, the spoilers’ effectiveness decreases significantly in comparison to the unswept wing. Strong spanwise flow develops for the leading-edge spoiler, which sheds a streamwise vortex, with the same direction of rotation as the wing-tip trailing vortex. This causes partial reattachment of the flow and reduction of the separation area behind the spoiler. With increasing reduced frequency, strong leading-edge vortices dominate the flow over the wing. The leading-edge vortices generate additional vortex lift and also cause the trailing-edge spoiler to be immersed in the massively separated flows. Both factors reduce the effectiveness of the spoilers.

Preserving or improving biodiversity outcomes requires a coordinated approach across policy levels and land managers. Agri-environmental collectives in the Netherlands adapt environmental policies to local conditions and coordinate the conservation efforts of their members. This paper describes the functions performed by the Dutch collectives through a meso-institutional lens and assesses whether the effectiveness of agri-environmental schemes has improved since the introduction of the collective approach. To this end, we use a case study of one of the Dutch collectives, and a mixed-methods approach including interviews and quantitative assessments of changes in the spatial coordination of the agri-environmental scheme for meadow bird conservation since the introduction of the collective scheme. The analysis shows an increase in contracted farmland area and spatial coordination of the contracted measures on these farmlands. The results highlight the potential value of the collective approach for the implementation of environmental policies for biodiversity.

This article is an introduction and guide to investigating past relationships between climate and human behavior. Improving understanding of these relationships is essential as humanity confronts the challenges of our warming world. However, how to investigate potential climatic influences on human behavior in the past is rarely presented or discussed as a distinct mode of inquiry. This article aims to fill this gap by providing a practical tool kit for students, archaeologists, anthropologists, and other historically focused social scientists. It is structured as a series of seven key steps to creating a research design for a climate and human behavior study, from identifying research questions to presenting results. Most of the conceptual models, methods, data, and examples provided have worldwide relevance and are informed by the long history of climate and human behavior studies in the North American Southwest. By expanding competence in this domain, we can enrich documentation and interpretations of the past and insights will emerge that will contribute to preparing for and responding to our warming world.

Medicinal cannabis has been trialled for Tourette syndrome in adults, but it has not been studied in adolescents. This open-label, single-arm trial study evaluated the feasibility, acceptability and signal of efficacy of medicinal cannabis in adolescents (12–18 years), using a Δ9-tetrahydrocannabinol:cannabidiol ratio of 10:15, with dose varying from 5 to 20 mg/day based on body weight and response. The study demonstrated feasibility of recruitment, acceptability of study procedures, potential benefits and a favourable safety profile, with no serious adverse events. Commonly reported adverse events were tiredness and drowsiness, followed by dry mouth. Statistically significant improvement was observed in parent and clinician reports on tics (paired t-test P = 0.003), and behavioural and emotional issues (paired t-test P = 0.048) and quality of life as reported by the parent and young person (paired t-test P = 0.027 and 0.032, respectively). A larger-scale, randomised controlled trial is needed to validate these findings.

The family of relevant logics can be faceted by a hierarchy of increasingly fine-grained variable sharing properties—requiring that in valid entailments $A\to B$, some atom must appear in both A and B with some additional condition (e.g., with the same sign or nested within the same number of conditionals). In this paper, we consider an incredibly strong variable sharing property of lericone relevance that takes into account the path of negations and conditionals in which an atom appears in the parse trees of the antecedent and consequent. We show that this property of lericone relevance holds of the relevant logic $\mathbf {BM}$ (and that a related property of faithful lericone relevance holds of $\mathbf {B}$) and characterize the largest fragments of classical logic with these properties. Along the way, we consider the consequences for lericone relevance for the theory of subject-matter, for Logan’s notion of hyperformalism, and for the very definition of a relevant logic itself.

In previous publications, it was shown that finite non-deterministic matrices are quite powerful in providing semantics for a large class of normal and non-normal modal logics. However, some modal logics, such as those whose axiom systems contained the Löb axiom or the McKinsey formula, were not analyzed via non-deterministic semantics. Furthermore, other modal rules than the rule of necessitation were not yet characterized in the framework.

In this paper, we will overcome this shortcoming and present a novel approach for constructing semantics for normal and non-normal modal logics that is based on restricted non-deterministic matrices. This approach not only offers a uniform semantical framework for modal logics, while keeping the interpretation of the involved modal operators the same, and thus making different systems of modal logic comparable. It might also lead to a new understanding of the concept of modality.

Antarctica, which has always been of great interest to researchers worldwide, is currently attracting considerable attention owing to climate change and other topics. In this context, bibliometric analysis allows the identification of hot topics, scientific productivity, cooperation, research gaps and strategic areas of potential interest. We conducted a bibliometric study to evaluate the global production of Antarctic research between 1980 and 2023 and analysed Spanish National Antarctic Programme (NAP) production as a case study. Scientific publications were reviewed and classified based on their main themes, key word co-occurrence and international collaborations. We found that scientific production worldwide and in the Spanish NAP has progressively increased since 1980. Globally, the main areas of research are the geosciences, oceanography and atmospheric sciences. However, the Spanish NAP, which reported 2287 publications, has focused more on the geosciences and ecology. Spanish Antarctic researchers have mainly collaborated with researchers from the USA, the UK, Germany and Italy. Our research highlights the importance of strengthening research plans to diversify and facilitate international collaboration, promoting a more interdisciplinary approach to address the current and future challenges identified by the scientific community. In this context, specific opportunities for developing a Spanish NAP strategic plan are discussed.

In the post-World War II period, as they faced a spate of prison riots and rising concerns about juvenile delinquency, many states set up penal forestry camps. Portrayed as a progressive step that would make incarcerated people fit for freedom through healthy work in natural settings, forestry camps also promised to contribute to the public good by fulfilling the forests’ manpower needs. At a moment when outdoor leisure was increasingly popular, the work of incarcerated workers helped create infrastructures that would make forests accessible to visitors. Using primarily the case of Washington state, this article shows how and why incarcerated people became a material and ideological resource for the state. It also shows how official discourse about forestry camps clashed with material and human realities on the ground.

How should epistemologists respond to skepticism about knowledge of the external world? Michael Bergmann advocates noninferential antiskepticism. The thought is that, to reply to a skeptical argument, we should start with premises that do not require inference. I argue that Bergmann’s reasoning runs into the problem of easy knowledge and propose an alternative inferential antiskepticism. This view faces the problem of vicious circularity. I agree that, if we go down the inferential path, a certain type of circularity is unavoidable. I deny, however, that this type of circularity is vicious.