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After an introduction to the notions of cybersecurity and cybersecurity-related risks, this preface introduces four collected contributions on challenges and perspectives of EU cybersecurity policies in cyber-physical ecosystem.
We establish two complementary results about the regularity of the solution of the periodic initial value problem for the linear Benjamin–Ono equation. We first give a new simple proof of the statement that, for a dense countable set of the time variable, the solution is a finite linear combination of copies of the initial condition and of its Hilbert transform. In particular, this implies that discontinuities in the initial condition are propagated in the solution as logarithmic cusps. We then show that, if the initial condition is of bounded variation (and even if it is not continuous), for almost every time the graph of the solution in space is continuous but fractal, with upper Minkowski dimension equal to $\frac32$. In order to illustrate this striking dichotomy, in the final section, we include accurate numerical evaluations of the solution profile, as well as estimates of its box-counting dimension for two canonical choices of irrational time.
As cities like Beijing expand rapidly, green and blue spaces (GBS)—essential for ecosystem services (ESs) such as clean air, flood control, and recreation—are increasingly threatened. This 20-year study examines how urban expansion and policy interventions have shaped Beijing’s GBS. While green initiatives have increased natural areas, unchecked urban sprawl has fragmented these spaces, reducing their environmental benefits. Satellite data and urban planning analyses underscore a key lesson: maintaining well-connected natural zones is critical for urban resilience. These findings are broadly applicable for rapidly growing cities globally, urging urban planners to integrate ecological conservation with development, and to safeguard healthy environments and vibrant communities.
Technical Summary
This study quantifies the spatiotemporal dynamics of urban GBS in Beijing, evaluating their essential role in delivering ESs and strengthening urban resilience. Although China has achieved substantial progress in urban greening, the ecological impacts of rapid urbanization on GBS configuration and connectivity have not been comprehensively quantified. Using an integrated analytical framework combining principal component analysis and multiple linear regression, we reveal how urban development strategies have shaped GBS dynamics over two decades. A spatially explicit analysis, utilizing geographically weighted regression, further elucidates the heterogeneous relationships among the normalized difference vegetation index, human footprint index, and ESs delivery capacity. Notably, socioeconomic incentives and green infrastructure governance—especially objective indicators such as forest, garden, and greenspace area—have effectively driven GBS expansion. However, urban expansion has led to pronounced fragmentation of peri-urban GBS, suggesting potential degradation of their ecosystem service support functions. These findings emphasize the need for adaptive GBS management strategies that balance ecological conservation with sustainable urban growth in rapidly developing cities.
Social Media Summary
Urban growth fragments green and blue spaces, reducing vital ecosystem services. Balancing conservation with development is essential for sustainable cities.
This chapter recapitulates the main findings of this study, relating them to the concepts of ‘oligarchy’, the boni and different forms of social power.
We examine the performance of microbial cell-free DNA (mcfDNA) next-generation sequencing (NGS) testing on patients admitted to a quaternary care hospital in Houston, Texas. The test was 75.0% sensitive and 97.8% specific for all mycobacterial infections. mcfDNA NGS results led to adjustments in antimicrobial therapy for seven of nine patients with positive results.
Not all persons sui iuris with the requisite wealth for municipal office were represented in the local municipal councils. This chapter assesses the prevalence of four different groups of such individuals in early-imperial Italy: the Augustales, male minors and women sui iuris, and persons lacking local citizenship (incolae and attributi).
Difficulties in executive functions (EFs) and internalizing and externalizing problems are prospectively related. However, it remains unclear whether the bidirectional relations between specific EF components and internalizing and externalizing problems at the within-person level vary across developmental stages in childhood and early adolescence.
Methods
This study utilized data from seven waves of the Early Childhood Longitudinal Study, Kindergarten Class of 2010–2011 (ECLS-K: 2011), following a nationally representative sample of 15,055 children (mean age at baseline = 5.63 years, SD = 0.37; age range = 4.02–7.83) from kindergarten through fifth grade. Internalizing and externalizing problems and inhibitory control were assessed using teacher-reported measures, while working memory and cognitive flexibility were evaluated using standardized cognitive tasks. Data were analyzed using a random intercept cross-lagged panel model, adjusting for the complex sampling design.
Results
Working memory negatively predicted internalizing problems from kindergarten to first grade, with no significant link to externalizing problems. Cognitive flexibility showed limited effects, with only spring kindergarten externalizing problems predicting lower cognitive flexibility in first grade. Inhibitory control negatively predicted internalizing problems in early childhood, while internalizing problems positively predicted inhibitory control during the kindergarten-to-first-grade transition. Externalizing problems consistently reduced inhibitory control over time. Notably, inhibitory control negatively predicted externalizing problems until third grade but positively predicted them from third to fourth grade.
Conclusions
The findings suggest that while certain EFs can protect against internalizing and externalizing problems in early childhood, these symptoms may also influence EF development, with these interactions evolving as children transition into adolescence.
Staphylococcus aureus bacteriuria (SABU) may represent bacteremia in a subset of patients. We describe the impact of a microbiology alert recommending follow-up blood cultures (FUBC) for patients with SABU in a large integrated health system.
Methods:
We conducted a quasi-experimental implementation study in adult ambulatory patients with documented SABU. We excluded patients with confirmed SAB up to 14 days prior to index SABU culture and with blood cultures obtained on the day of SABU. The primary outcome was rate of FUBC (collected between 1 and 5 days of SABU) among all cases of SABU. Secondary outcomes included percentage of patients with early SAB (collected between 1 and 5 days of SABU). We used interrupted time series analysis to compare rates of FUBC pre vs postintervention.
Results:
A total of 2 540 patients were identified; 1 213 (48%) were male. By the end of the postintervention period, the rate of FUBC (20.6%) had increased by 6.3 percentage points (P = .005) compared to the counterfactual (14.2%) had no intervention taken place (44.5% relative increase). Early SAB detection due to FUBC increased from .6% preintervention to 2.0% postintervention (P = .004).
Conclusion:
The microbiology alert initiative increased FUBC in patients with SABU by 44%, but the overall rate of FUBC remained low. The intervention increased early SAB detection. Risk-targeted strategies are needed to optimize FUBC collection in patients with SABU.
This article aims to explore the social representations of the Spanish Second Republic and the Transition epochs among university students of various national identities within the Spanish state. A free-association exercise elicited by the words ‘Second Republic’ and ‘Transition’ was completed by 477 university students of the Basque Country, Catalonia, Galicia, and Madrid, who were also asked about their national identity ideological orientation. Lexical analysis was used to analyse their responses. The results demonstrate how these two periods are strongly anchored in the ideological affiliations and social identity of the participants. Furthermore, we observed that the Spanish identity and right-wing ideology were related to a narrative crafted by the political elites during the inception of the current democratic period. Meanwhile, the peripheral national identities and left-wing ideology were associated with a contentious narrative that responds to the contested narrative. In addition, the results also reveal the current relevance of these two periods through their symbols and transmission, whose senses and meanings differ based on the ideological affiliation and national identity of the participants.
This article provides a comparative discussion of the theories of imperialism developed by three prominent scholars – Paul Samuel Reinsch, Ukita Kazutami, and Liang Qichao – in the 1900s. Such a discussion offers a fresh understanding of imperialism in the East Asian context from three perspectives. First, by revealing inter-textual connections between the three figures’ writings, it sheds light on Japan’s mediating role in the formation of Chinese knowledge of imperialism in a transpacific exchange of ideas. Second, it examines how the theories of imperialism travelled in the unequal international spaces created by practices of imperialism. Last, it draws attention to the consequences of embracing the Western ideal of national empire in East Asia, highlighting the fact that some Japanese and Chinese elites resisted Western imperialism on the one hand, but, on the other, drew inspiration from the ideal of imperialism to formulate their own expansionist agendas.
Healthcare-associated infections (HAIs) result in substantial patient harm and avoidable costs. Pay-for-performance programs (PFP) through the Centers for Medicare and Medicaid Services (CMS) have resulted in reductions of HAIs like central line-associated bloodstream infections (CLABSI) and methicillin-resistant Staphylococcus aureus bacteremia, through robust infection prevention programs and practices. Hospital Onset Bacteremia and Fungemia (HOB) is proposed as an alternative quality measure for public reporting and PFP, and was endorsed by the National Quality Forum in 2022. This broad measure is designed as an electronic quality measure that avoids manual abstraction and excludes risk adjustment. HOB would substantially expand the scope of focus of existing bloodstream infection measurement, and is currently being considered for voluntary reporting in 2025. In this article, we provide arguments for and against adopting HOB as a PFP measure linked to CMS payments.
This is a proof-of-concept study to compare the effects of a 2-week program of “Remind-to-move” (RTM) treatment using closed-loop and open-loop wearables for hemiparetic upper extremity in patients with chronic stroke in the community. The RTM open-loop wearable device has been proven in our previous studies to be useful to address the learned nonuse phenomenon of the hemiparetic upper extremity. A closed-loop RTM wearable device, which emits reminding cues according to actual arm use, was developed in this study. A convenience sample of 16 participants with chronic unilateral stroke recruited in the community was engaged in repetitive upper extremity task-specific practice for 2 weeks while wearing either a closed-loop or an open-loop ambulatory RTM wearable device on their affected hand for 3 hrs a day. Evaluations were conducted at pre-/post-intervention and follow-up after 4 weeks using upper extremity motor performance behavioral measures, actual arm use questionnaire, and the kinematic data obtained from the device. Results showed that both open-loop and closed-loop training groups achieved significant gains in all measures at posttest and follow-up evaluations. The closed-loop group showed a more significant improvement in movement frequency, hand functions, and actual arm use than did the open-loop group. Our findings supported the use of closed-loop wearables, which showed greater effects in terms of promoting the hand use of the hemiparetic upper extremity than open-loop wearables among patients with chronic stroke.
This chapter examines the formal relationship between medical professionalism and compassion, looking at codes of ethics and practice guidelines, chiefly for medical professionals but also with reference to other healthcare workers. The chapter starts by exploring the importance accorded to compassion in ethical guidance for doctors in the United Kingdom (UK), Ireland, the United States, Australia, and New Zealand. It then examines guidance specifically aimed at psychiatrists, including documents published by the Royal College of Psychiatrists in the UK, the College of Psychiatrists of Ireland, and the American Psychiatric Association. Many of these guides emphasise the importance of compassion and related values, with the Royal College of Psychiatrists providing particularly detailed suggestions about building and sustaining compassion in mental healthcare. Compassion and related values also feature commonly in codes of practice and ethical guidance for other clinical professionals, such as nurses, midwives, social workers, occupational therapists, and others. This chapter concludes that, taken together, these statements of practice values and ethical principles reflect a welcome and growing emphasis on compassion in guidance for healthcare professionals across many clinical domains.
Ocean submesoscales, flows with characteristic size $10\,\text{m}{-}10\,\text{km}$, are transitional between the larger, rotationally constrained mesoscale and three-dimensional turbulence. In this paper, we present simulations of a submesoscale ocean filament. In our case, the filament is strongly sheared in both vertical and cross-filament directions, and is unstable. Instability indeed dominates the early behaviour with a fast extraction of kinetic energy from the vertically sheared thermal wind. However, the instability that emerges does not exhibit characteristics that match the perhaps expected symmetric or Kelvin–Helmholtz instabilities, and appears to be non-normal in nature. The prominence of the transient response depends on the initial noise, and for large initial noise amplitudes, saturates before symmetric instability normal modes are able to develop. The action of the instability is sufficiently rapid – with energy extraction from the mean flow emerging and peaking within the first inertial period ($\sim\! 18\ \text{h}$) – that the filament does not respond in a geostrophically balanced sense. Instead, at all initial noise levels, it later exhibits vertically sheared near-inertial oscillations with higher amplitude as the initial minimum Richardson number decreases. Horizontal gradients strengthen only briefly as the fronts restratify. These unstable filaments can be generated by strong mixing events at pre-existing stable structures; we also caution against inadvertently triggering this response in idealised studies that start in a very unstable state.
Bubbles entrained by breaking waves rise to the ocean surface, where they cluster before bursting and release droplets into the atmosphere. The ejected drops and dry aerosol particles, left behind after the liquid drop evaporates, affect the radiative balance of the atmosphere and can act as cloud condensation nuclei. The remaining uncertainties surrounding the sea spray emissions function motivate controlled laboratory experiments that directly measure and link collective bursting bubbles and the associated drops and sea salt aerosols. We perform experiments in artificial seawater for a wide range of bubble size distributions, measuring both bulk and surface bubble distributions (measured radii from $30\,\unicode{x03BC} \mathrm{m}$ to $5\,\mathrm{mm}$), together with the associated drop size distribution (salt aerosols and drops of measured radii from $50\,\mathrm{nm}$ to $500\,\unicode{x03BC} \mathrm{m}$) to quantify the link between emitted drops and bursting surface bubbles. We evaluate how well the individual bubble bursting scaling laws describe our data across all scales and demonstrate that the measured drop production by collective bubble bursting can be represented by a single framework integrating individual bursting scaling laws over the various bubble sizes present in our experiments. We show that film drop production by bubbles between $100\,\unicode{x03BC} \mathrm{m}$ and $1\,\mathrm{mm}$ describes the submicron drop production, while jet drop production by bubbles from $30\,\unicode{x03BC} \mathrm{m}$ to $2\,\mathrm{mm}$ describes the production of drops larger than $1\,\unicode{x03BC} \mathrm{m}$. Our work confirms that sea spray emission functions based on individual bursting processes are reasonably accurate as long as the surface bursting bubble size distribution is known.
This chapter contends that Italy was exceptionally wealthy during the Early Empire, both in real and nominal terms. Italy’s prosperity stemmed from several sources: substantial booty, taxes, and rents were diverted from the provinces to the empire’s core; provincial elites engaged in imperial politics were expected to spend lavishly in Rome and its environs; and returns on Italian land were relatively high. Additionally, high prices in Italy for both real estate and commodities augmented Italy’s wealth in nominal terms.
This chapter argues that men with the requisite wealth for political office outside the political orders contributed to the stability of the Roman timocratic political system by serving as a reserve pool from which new magistrates and councillors were recruited. Correspondences between the surpluses of wealthy households at the senatorial, equestrian, and curial levels of the political system, and evidence of shortages of candidates at these levels, substantiate this argument.
We present the results of a theoretical investigation of orbital stability in pilot-wave hydrodynamics, wherein a droplet bounces and self-propels across the surface of a vertically vibrating liquid bath. A critical notion in pilot-wave hydrodynamics is that the bath plays the role of the system memory, recording the history of the droplet in its wave field. Quantised orbital motion may arise when the droplet is confined by either an axisymmetric potential or the Coriolis force induced by system rotation. We here elucidate the dependence of the stability of circular orbits on both the form of the confining force and the system memory. We first provide physical insight by distinguishing between potential- and wave-driven instabilities. We demonstrate that the former are a generic feature of classical orbital dynamics at constant speed, while the latter are peculiar to pilot-wave systems. The wave-driven instabilities are marked by radial perturbations that either grow monotonically or oscillate at an integer multiple of the orbital frequency, in which case they are said to be resonant. Conversely, for potential-driven wobbling, the instability frequency may be resonant or non-resonant according to the form of the applied potential. Asymptotic analysis rationalises the different stability characteristics for linear-spring and Coriolis forces, the two cases that have been explored experimentally. Our results are generalised to consider other potentials of interest in pilot-wave hydrodynamics, and elucidate the distinct roles of wave- and potential-driven instabilities. Our study highlights the limitations of prior heuristic arguments for predicting the onset of orbital instability.