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How can philanthropy catalyse systemic change in an era of global crisis? As the world grapples with escalating climate risks, widening inequality, and shifting global power dynamics, traditional approaches to development finance are becoming insufficient. This book explores how philanthropy, as risk capital, can de-risk investments, unlock private capital, and drive transformative, multi-sector partnerships to tackle the most pressing global challenges. Bringing together real-world case studies and expert insights, it highlights blended finance models, climate adaptation strategies, and innovative approaches to sustainable development. The authors reveal how emerging markets are leading in catalytic finance, how philanthropy can scale green investments, and why collaboration is the only path to meaningful impact. A must-read for philanthropists, investors, policymakers, and development leaders, Catalytic Capital offers practical frameworks to harness the power of finance for a more resilient, inclusive, and sustainable global economy. This title is also available as Open Access on Cambridge Core.
Using ethnographic material of new parents’ encounters with welfare workers during the process of claiming and receipt of universal family entitlements in Denmark and Romania, this article proposes the concept of bureaucratic translation. Drawing on Latourian conceptual foundations, we show that the communication of bureaucratic information is not only symbolically loaded, but invariably in need of ‘translation’. We highlight five interrelated processes of meaning-making parents have to engage in. Despite the universalism of entitlements, parents experience information offered by welfare workers as specialised knowledge that they should not legitimately be expected to have good command of. Their contestation stems from the tension between the helping ethos of universalist programmes and the inadequacies and insufficiencies of bureaucratic information offered. Bureaucratic translation illuminates the complexities of ‘learning costs’ underpinning administrative burden from citizens’ perspective, flagging difficulties even for the bureaucratically least challenging social programmes.
The crystal structure of fluvoxamine hydrogen maleate has been solved and refined using synchrotron X-ray powder diffraction data and optimized using density functional theory techniques. Fluvoxamine maleate crystallizes in space group P21/c (#14) with a = 21.6310(15), b = 5.3180(4), c = 19.5555(15) Å, β = 99.979(5)°, V = 2,215.48(25) Å3, and Z = 4 at 298 K. The crystal structure consists of alternating double layers of cations and anions parallel to the bc-plane. Hydrogen bonds link the layers of anions and cations parallel to the bc-plane. The powder pattern has been submitted to the International Centre for Diffraction Data for inclusion in the Powder Diffraction File™ (PDF®).
We present a Late Pleistocene paleoecological record from King Island in western Bass Strait, Tasmania, and compare this to existing records from the eastern Bass Strait islands to improve our understanding of the region’s paleoecology and paleoclimatology. Vegetation change across the region followed similar trajectories during the late glacial–Middle Holocene, characterized by homogeneous warming and wetting trends. Spatial divergence occurred during the Middle Holocene when sea level rose, and different drivers began influencing western and eastern Bass Strait islands. In eastern Bass Strait, Middle Holocene sea-level rise caused replacement of woodland by coastal heathland, while in the west, a drier period accompanied by fires transformed forests to forest–scrub. The comparative analysis suggests that Westerly driven climatic anti-phasing was pronounced at higher latitudes of Tasmania during the late glacial–Early Holocene. A combination of weak Leeuwin Current, positive Indian Ocean Dipole (IOD), and El Niño–Southern Oscillation (ENSO) intensification contributed to Middle Holocene aridity across Bass Strait. Strong Westerlies and negative IOD phases led to greater regionalization of rainfall across western Bass Strait during the Late Holocene, while ENSO intensification drove rainfall declines in eastern Bass Strait. These findings provide new insights into the complexity of Late Pleistocene environmental dynamics across southeast Australia.
In Chapter 5 of Transparency and Reflection, Matthew Boyle examines an “anti-Egoist” challenge to my reflective knowledge that I am thinking, which says all I really know is that thinking is occurring. Boyle replies that I know something more, namely that a subject is thinking. Even so, he concedes that traditional Egoists like Descartes go too far in claiming reflective knowledge that an object is thinking. However, these comments argue that there is no stable middle ground between Cartesian Egoism and Anti-Egoism. If I know that I am thinking, then I know that an object is thinking.
En este trabajo estudio el arte rupestre creado por los zapotecos a su llegada a la parte sur del Istmo de Tehuantepec en el Postclásico tardío. Analizo varios aspectos de este arte desde una aproximación a la ontología zapoteca prehispánica para exponer la singularidad de este tipo de arte dentro de la cultura zapoteca, y para demostrar que constituía una acción y una experiencia diferente de lo que se considera arte en la tradición clásica de occidente, ya que se pintaba sobre un ente vivo. Propongo dos aspectos importantes de la estética de este arte: la vinculación íntima con la tierra como ente vivo y con los seres que habitan en su interior; y el poder de poner en acción esas imágenes que desataba su proceso de creación.
To explore the impact of an immersive virtual reality (VR) training module on infection prevention and control (IPC) knowledge and attitudes of healthcare personnel (HCP) and to demonstrate the use of VR for performance assessment in cleaning and disinfection of portable medical equipment (PME).
Design:
Quasi-experimental study.
Setting:
Two academic medical centers and three long-term care facilities.
Participants:
HCP in clinical roles were recruited.
Methods:
Pilot sites trained participants on an immersive VR training module on PME cleaning and disinfection. Participants completed the VR module and pre- and post-knowledge and attitude assessment surveys, including a post-survey on the user experience of the VR module. Performance data were collected from the head-mounted displays (HMD) on the duration of the VR session, and participant performance including in-module task completion, hand hygiene compliance, PME disinfection percentage, and in-module quiz performance. Statistical significance and effect size were calculated using paired sample t-tests and Cohen’s D for pre- and post-survey results. HMD data were analyzed using descriptive statistics.
Results:
A total of 60 participants were recruited; 54 were included for analysis, with improvements in knowledge and attitudes post-training. Participant user experience was rated 50.19/55. HMD data demonstrated: 22-minute mean module duration, mean of 2.15/28 tasks not completed, mean of 2.56 missed hand hygiene opportunities, and 54% PME mean disinfection percentage, and varied performance on in-module quizzes.
Conclusions:
Immersive VR training may be effective in improving HCP knowledge and attitudes in IPC concepts. Performance data collected through VR training can evaluate learner performance and be used to target training for improvement.
The rise of China as a global power has been a prominent feature in international politics. Simultaneously, the United States has been engaged in ongoing conflicts in the Middle East and South Asia for the past two decades, requiring a significant commitment of resources, focus, and determination. This paper investigates how third-party countries react to the United States’ preoccupation with these conflicts, particularly in terms of diplomatic co-operation and alignment. We introduce a measure of US distraction and utilize network-based indicators to assess diplomatic co-operation or alignment. Our study tests the hypothesis that when the US is distracted, other states are more likely to co-operate with its principal rival, China. Our findings support this hypothesis, revealing that increased co-operation with China is more probable during periods of US distraction. However, a closer examination of state responses shows that democracies distance themselves from China under these circumstances, while non-democracies move closer.
This study offers a review of the artistic dimension of the Chinchorro culture, a complex hunter-gatherer society along the coast of the Atacama Desert that, around 7000 years ago, created elaborate representations of the dead. It provides archaeological background and investigates the possible reasons for the development of artificial mummification. Drawing on the art therapy model and the concepts of art and grief, the analysis interprets Chinchorro mortuary rituals as expressions of emotional and social processes. This study argues that these anthropogenically prepared mummies represent artistic expressions that reflect the intentional decision-making and emotional awareness of these ancient communities, serving as a means to process grief. Furthermore, the paper highlights the multifaceted nature of Chinchorro society, including the mining and use of pigments such as manganese—materials that, while symbolically meaningful, posed serious health risks and may have contributed to the eventual decline of their elaborate funerary practices. Finally, the study underscores the enduring cultural significance of the Chinchorro, particularly in shaping contemporary identity of Arica region, where artistic portrayal of dead links ancient and modern narratives of cultural heritage.
In this paper, we show that if $\mathscr{C}$ is a category and if $F\colon \mathscr{C}^{\;\textrm {op}} \to \mathfrak{Cat}$ is a pseudofunctor such that for each object $X$ of $\mathscr{C}$ the category $F(X)$ is a tangent category and for each morphism $f$ of $\mathscr{C}$ the functor $F(\,f)$ is part of a strong tangent morphism $(F(\,f),\!\,_{f}{\alpha })$ and that furthermore the natural transformations $\!\,_{f}{\alpha }$ vary pseudonaturally in $\mathscr{C}^{\;\textrm {op}}$, then there is a tangent structure on the pseudolimit $\mathbf{PC}(F)$ which is induced by the tangent structures on the categories $F(X)$ together with how they vary through the functors $F(\,f)$. We use this observation to show that the forgetful $2$-functor $\operatorname {Forget}:\mathfrak{Tan} \to \mathfrak{Cat}$ creates and preserves pseudolimits indexed by $1$-categories. As an application, this allows us to describe how equivariant descent interacts with the tangent structures on the category of smooth (real) manifolds and on various categories of (algebraic) varieties over a field.
Implementation science plays a crucial role in effectively translating scientific knowledge into sustainable, evidence-based health practices. This perspective article focuses on some Latin American experiences, highlighting the limitations of applying methodologies developed in the Global North to settings marked by structural inequalities, economic constraints and cultural diversity. The included experiences examine a range of programs, such as the national Breastfeeding and Feeding Strategy, the evaluation of the Triple P-Positive Parenting Program in Chile and the community component of Mental Health Gap Action Programme in Colombia. Other contributions explore professional training initiatives and offer critical reflections on frameworks, such as the Consolidated Framework for Implementation Research and the Reach, Effectiveness, Adoption, Implementation and Maintenance. The reflections call for strengthening local capacities, fostering meaningful South–South and South–North collaborations, and advancing a context-sensitive, equity-oriented approach to implementation science that supports the development of more adaptive, effective and just health systems.
Youth who are lesbian, gay, bisexual, transgender, queer or questioning, and other diverse sexual and gender identities (LGBTQ+) experience disproportionately high rates of suicidal thoughts and behaviors compared to heterosexual and cisgender peers, yet many face barriers to care. Data came from a national online survey of 18,663 LGBTQ+ youth aged 13–24 years in the United States (September–December 2023). Analyses focused on participants who reported wanting mental health care in the past year and assessed access, barriers, service modalities and suicidal ideation/attempts. Half of LGBTQ+ youth who wanted mental health care did not receive it. The most common barrier was fear of talking about mental health concerns (42%). Among those who received care, one-on-one therapy was most common (69% in-person and 53% online). Suicidal ideation was lower among youth in therapy (46% in-person and 40% online) compared to those using crisis lines (75%). After adjusting for demographics, hotline use remained strongly associated with elevated risk: adjusted odds ratio (aOR) = 3.77 (95% confidence interval [CI]: 3.11–4.56) for suicidal ideation; aOR = 3.21 (95% CI: 2.62–3.94) for attempts. Despite strong willingness to seek care, structural and identity-related barriers leave many needs unmet. Expanding culturally competent services is essential to reducing suicide risk.
Most OECD member countries operate within political economies shaped by capitalist neoliberal policies, and economic viability appears essential for maintaining stable commercial operations, including farming enterprises. However, urban and peri-urban farming in these countries is often viewed through a lens of multifunctionality, emphasizing environmental and social sustainability, while giving less attention to economic sustainability. A scoping review was undertaken to identify factors affecting the economic sustainability and associated viability of soil-based commercial farms located in urban and peri-urban settings within OECD member countries. Following the PRISMA ScR methodology, four scientific databases were searched, resulting in 2,389 potential articles, of which 170 were eligible for inclusion. Narrative synthesis identified that many urban/peri-urban farms are small in scale and employ a range of strategies to minimize costs and maximize efficiencies due to limited land availability as well as high land and labor costs common in and around metropolitan locations within OECD member countries. These strategies include direct distribution, production refinements, circularization of resources, differentiation and diversification strategies, as well as building relationships of reciprocity with the local community. External factors such as the policy and governance context, availability of skilled labor and education, and mentoring opportunities also influence the likelihood of success of urban farming. Some urban farms are developing alternative economic and organizational models, where their viability depends on factors that may not be captured by conventional financial metrics. This review found that many soil-based urban farms in OECD countries struggle to achieve economic sustainability or organizational viability. Successful organizations are those that refine operational, technical, and human systems within the farm, while also responding to their broader social, political, and ecological context.
This article considers whether Members of the World Trade Organization (WTO) can develop a collective response to a globally welfare-damaging situation that impacts individual Members differentially. We conclude that collective action remains within the letter and spirit of the WTO Agreements. We set out the enabling procedures for collective action in a WTO dispute setting, in particular, the use of the rarely used situation complaint. We were motivated by the United States’ move to redraw its trade relations and break from its international trade commitments through bilateral negotiations in which it holds asymmetric leverage, buttressed by a pre-emptive announced escalation in response to any attempt by counterparties to join in forging a collective response. We conclude that, if undertaken, collective action can raise each Member’s voice into a countervailing choir and, more importantly, it can reinforce the mutual benefits derived from the multilateral trading system. Collective action thus serves a double purpose in engaging domestic concerns and the collective interests of those intending to preserve the multilateral system on which each Member depends.
This article examines the evolution of a political order built on its citizens’ ambitious self-government and achievement and how the fit body became key to this order. In the first part, the article traces the origins of our current understanding of fitness back to the writings of John Locke and the invention of human agency and an ambitious pursuit of achievement as political paradigms. The second part moves on to the nineteenth century and shows how the body moved to the center of ambitious attention and how working on one’s body indicated a desire and responsibility for achievement. In the United States in particular, improving one’s physical ability meant living up to the demands of good citizenship. The article argues that fitness is a liberal political practice, and at the same time it means voluntary submission to the normative ideal of achievement and successful subjecthood.
Learners’ confidence in using a second language (L2 self-efficacy) and their L2 grit are key psychological factors in developing intercultural competence (ICC). As English as a foreign language (EFL) students increasingly encounter diverse cultures though informal digital learning of English (IDLE), this study examines whether IDLE serves as a pathway connecting these psychological traits to ICC. Grounded in the broaden-and-build theory, this explanatory mixed-methods research investigates how L2 self-efficacy and grit contribute to ICC through IDLE among 416 Chinese EFL students. Structural equation modeling revealed that higher L2 self-efficacy fosters greater L2 grit, which in turn promotes more frequent engagement in both receptive IDLE activities (e.g. watching English media) and productive ones (e.g. participating in online conversations). This increased engagement was positively linked to higher levels of ICC. Qualitative findings further illuminated the mechanisms behind this process, illustrating how psychological strengths support meaningful digital encounters across cultures. The findings offer pedagogical insights: by cultivating students’ self-efficacy and grit, educators can encourage deeper engagement in IDLE, thereby equipping learners with effective and culturally sensitive communication in an increasingly interconnected digital world.
This study evaluated whether brief teaching sessions on transference-focused psychotherapy (TFP) could improve psychiatric trainees’ attitudes and clinical confidence in managing patients with personality disorders. A mixed-methods design was used, combining pre- and post-training validated questionnaires with a focus group discussion. Two 4-h workshops covered TFP theory and techniques, and case discussions.
Results
Twenty-six participants completed paired questionnaires. Statistically significant improvements were observed in overall attitudes (Attitudes to Personality Disorder Questionnaire total score, P = 0.022) and enthusiasm towards patients with personality disorders (P = 0.003). Clinical confidence (Clinical Confidence with Personality Disorder Questionnaire) improved markedly (P < 0.001). Qualitative analysis identified high acceptability, valuing TFP concepts and enhanced emotional awareness, although participants desired more practical components.
Clinical implications
Even brief TFP training can positively influence trainees’ attitudes and confidence in treating personality disorders. Incorporating TFP-informed training into psychiatric education may reduce clinician frustration and improve therapeutic engagement with this complex patient group.
The menopausal period in women is characterized by neuroendocrine alterations, which is in part mediated by the reduction in circulating estrogen. During this transition, many perimenopausal and menopausal women experience sleep disturbances and increased susceptibility to sleep-related disorders. Sleep disruptions are partially attributed to nighttime vasomotor symptoms (VMS), which exacerbates the insomnia risk in the menopausal woman. Converging data implicate the orexin system in the pathophysiology of insomnia and VMS, particularly through regulation of arousal, thermoregulation, and sympathetic outputs. Estrogen decline due to menopause is postulated to modulate orexin signaling, thereby heightening sympathetic drive and thermoregulatory instability. Given this potential mechanistic framework, orexin receptor antagonists, notably dual orexin receptor antagonists (DORAs), have been proposed as alternative menopausal therapeutics. Herein, we aim to examine preclinical, translation, and clinical literature assessing the therapeutic potentials of DORAs as a nonhormonal intervention for the mitigation of insomnia and VMS in midlife women.