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This chapter focuses on resilience and compassion, starting by examining the relevance of resilience in healthcare, especially during the Covid-19 pandemic. The chapter notes that while a certain amount of resilience is helpful and even essential, resilience depends on not only the personal characteristics of each healthcare worker, but also the conditions in which they work. Relevant factors include the structure and function of teams, models of organisation, quality of leadership, and resources. These matters have an enormous influence on individual experiences, attitudes, and behaviour, and on the levels of resilience that are required and accessible in the workplace, as well as compassion. This chapter considers the concepts of ‘compassion fatigue’ and ‘burnout’, and outlines barriers to, and facilitators of, compassionate care. Systemic challenges include competing system demands, time constraints, inadequate resources, communication issues, poor emotional connections with the broader healthcare system, and the perception and/or reality of staff not being valued for the care they provide. These are themes that resonate with many people who work in large healthcare systems where organisational challenges loom large, often distracting focus from day-to-day patient care. This chapter also examines the roles of mindfulness and meditation in navigating these challenges.
Certain skills support compassion and help us to develop and sustain compassion even in circumstances that are far from ideal. Against this background, recent decades have seen a remarkable growth of research in this field. There is, in particular, a welcome flourishing in the area of compassion studies and compassion-based therapies, which form the focus of this chapter. Paul Gilbert, in particular, has developed compassion-focused therapy (CFT) which is outlined further by the Compassionate Mind Foundation and available in many countries around the world, as well as online. The Compassionate Mind Foundation advances an evolutionary and bio-psycho-social informed approach to compassion, and this forms the basis of CFT and ‘Compassionate Mind Training’. This chapter starts by exploring the origins of CFT and key attributes for the cultivation of compassion, before considering compassion and shame in clinical contexts. Shame can be an especially powerful emotion with a profound effect on health-related behaviour. Compassion can be a valuable way to address this issue. This chapter examines CFT in practice and notes the growing evidence base to support its use. The chapter concludes with further reflections on compassion and self-compassion as key skills and vital resources in healthcare.
In theory, compassion lies at the heart of all healthcare. There are, however, many reasons for the erosion of compassion in day-to-day clinical practice: increased demand on services, limited resources, large caseloads, insufficient time to spend with each patient, and a consequent transactional rather than relational approach to each person. Systemic focus on efficiency and throughput can also impede the cultivation of compassion, empathy, understanding, and addressing the individual needs and concerns of each patient and their family. Growing reliance on technology and electronic health records can further depersonalise patient interactions and reduce compassion, despite the many benefits of such technologies. This chapter outlines these and other factors which tend to diminish compassion, reflects on the relevance of overarching values in medical education, focuses especially on the meaning of ‘equanimity’ in this context, and overviews the place accorded to compassion in guides to professional ethics and codes of practice. The role of health systems in limiting compassion and empathy is balanced by evidence supporting the importance and possibilities of compassionate care, especially during times of emergency such as the Covid-19 pandemic in the early 2020s.
While evidence-based clinical practice guidelines promote high-quality care, their absence may create unwarranted variation in disease management, leading to suboptimal outcomes. This study aimed to identify existing clinical practice guidelines for tardive dyskinesia (TD) in France, Germany, Italy, Spain, and the United Kingdom (EU4+UK), assessing the evidence for recommended TD treatments.
Methods
MEDLINE, PubMed, and other sources (e.g., government/public agencies, associations, patient/research organizations) were searched to identify clinical practice guidelines for TD published between January 2000 and February 2025 in EU4+UK. Mentions of TD treatments in identified documents were classified as “recommendations” or “descriptions.” Recommendations were ranked according to the Scottish Intercollegiate Guidelines Network grading system or received a “no-rank” label. Subanalyses on tetrabenazine and tiapride, were performed.
Results
Of the 31 documents identified, only two were TD-specific, with the remainder primarily developed for schizophrenia, major depressive disorder, and bipolar disorder. Data extraction led to 112 mentions of TD treatments (40 recommendations, 72 descriptions). Most recommendations focused on antipsychotic regimen modification (75%) and had no rank (88%). Only five recommendations (no rank) proposed a pharmaceutical (add-on) treatment: three for tetrabenazine and one each for amantadine and buspirone. Neither of the TD-specific guidelines contained TD treatment recommendations.
Conclusions
No specific clinical practice guidelines for TD in EU4 + UK were found, although TD management was mentioned in guidelines for other disorders. Most recommendations were not supported by high-quality evidence. To improve quality of care for patients with TD in Europe, updated treatment recommendations are needed based on high-quality studies.
Despite its expanding presence in codes of practice and ethical guidance for healthcare professionals, there is limited research into the precise components of compassion in clinical settings. This chapter continues the exploration of compassion in healthcare by noting occasional confusion surrounding the term ‘compassion’, and the distress that an absence of compassion can cause for patients, families, and staff. The chapter examines research that seeks to define compassionate healthcare and delineate its constituent elements. Patients experience compassionate care when healthcare providers are emotionally present, communicate effectively, enter into their experience, and display understanding and kindness. Listening and paying close attention are the most dominant features of compassionate care, along with following‐up and running tests, continuity, holistic care, and respecting preferences. Other factors include honesty and kindness, as well as specific behaviours such as smiling. These are simple ways to demonstrate the compassion that healthcare workers routinely feel but sometimes do not convey clearly, owing to challenging circumstances. The chapter concludes with considerations of cultural and ethnic factors, as well as the importance of engagement, mindful awareness, and emotional intelligence in generating and deepening compassionate practice.
Shifts in food acquisition during the COVID-19 pandemic may have affected diet. Assessing changes in diet is needed to inform food assistance programs aimed at mitigating diet disparities during future crises. This longitudinal study assessed changes in diet among a low-income, racially diverse population from March-November 2020.
Methods
Survey data were collected from 291 adults living in Austin, TX. Multivariable ordinal logistic regression models assessed the relationship between changes in consumption of fresh, frozen, and canned fruits and vegetables (FV), and sugar-sweetened beverages (SSBs) and the following food acquisition factors: food security, difficulty finding food, food bank usage, and food shopping method.
Results
Adjusted models indicated individuals with consistent food insecurity had increased odds of reporting a higher category of consumption for frozen (aOR = 2.13, P < 0.05, CI:1.18-3.85) and canned (aOR = 4.04, P < 0.01, CI:2.27-7.20) FV and SSB (aOR = 3.01, P < 0.01, CI:1.65-5.51). Individuals who reported using a food bank were more likely to report increased consumption of frozen (aOR = 2.14, P < 0.05, CI:1.22-3.76) and canned FV (aOR = 2.91, P < 0.01, CI:1.69-4.99).
Conclusions
Shifts in food acquisition factors were associated with changes in diet. Findings demonstrate the need for more robust food assistance programs that specifically focus on all dimensions of food security.
Psychotic disorders, including schizophrenia (SZ), schizoaffective disorder (SZA), bipolar disorder (BD), psychotic depression (PD), and other nonaffective psychoses (ONAP), are associated with increased risk of suicidal acts. Few studies have compared suicidal act prevalence across psychotic disorders using both self-report and register data. The impact of hospitalization duration on subsequent suicidal acts is unclear.
Methods
We used data from the SUPER-Finland study, involving 7067 participants with register-based ICD-10 diagnoses of psychotic disorders (SZ, SZA, BD, PD, ONAP). Lifetime suicidal acts were identified through self-report and register-based records of intentional self-harm events requiring medical treatment. Associations between diagnostic categories and suicidal acts were assessed using logistic regression, adjusted for sex, duration of illness, socioeconomic status, childhood abuse, and substance use. Survival analysis was used to examine the impact of hospital stay length on postdischarge self-harm.
Results
Lifetime suicide attempts (39.1%) and register self-harm (19.3%) were prevalent. of those with self-reported suicide attempts, 40.5% also had register-based self-harm. Self-harm and suicide attempts were significantly more prevalent in SZA, BD, and PD compared to schizophrenia, with large differences between groups (24.1–46.4% for suicide attempts, 11.1–23.9% for self-harm). Adjusted odds of self-harm were higher for disorders with a mood component. Shorter hospitalizations were associated with an elevated hazard ratio for subsequent self-harm.
Conclusions
Prevalence of register-based self-harm and self-reported suicide attempts differ markedly. Suicidal acts are common in psychotic disorders, particularly in those with a mood component. Very short inpatient stays may not be adequate in these disorders.
This paper aims at reexamining external sustainability in a dynamic framework for nine European Monetary Union (EMU) countries during the period 1970–2021. We extend the approach of Bohn (1998) to a time-varying external reaction function. The main advantage of our empirical strategy is that it captures the dynamics of the external reaction function, by accounting for the main sources of heterogeneity among EMU countries and by including common factors like financial globalization and global risk aversion. To estimate the model, we employ a fully fledged state-space framework, which extends the simple model generally used in this literature to a panel-data time-varying parameter framework, combining fixed (common and country-specific) and varying components. Our results show an evident interplay between real and financial variables, the latter progressively increasing their importance. Although heterogeneous, the adjustment to external imbalances in most EU countries is jointly driven by the level reached in the stock of net foreign assets together with the degree of risk aversion and financial openness.
Awareness is the quality of knowing and understanding that something is happening or exists. It means bringing conscious attention to whatever is arising, with as little judgement as possible. On a subconscious level, we respond to what is happening in the moment by applying existing information in our brains to the external event. This response is often habitual or unaware, as we tread well-worn grooves in our brains and follow heuristics which help us to manage the vast amount of information that comes our way every moment. These cognitive shortcuts can be helpful, but they can limit our understanding, undermine our confidence in new situations, and diminish the attention we pay to what our bodies and minds tell us. Deepening awareness involves developing mindfulness, which means paying careful attention to the present moment, simply and directly, rather than being distracted by thoughts, judgements, or interpretations. Traditionally, there are four components or foundations of mindfulness. This framework allows us to develop awareness of all aspects of our experience. These are: (a) mindfulness of the body; (b) mindfulness of feelings or feeling-tone; (c) mindfulness of states of mind or emotions, and (d) mindfulness of thoughts. This chapter offers exercises and guidance for developing deeper awareness and mindfulness in day-to-day life.
A growing literature examines the relationship between compassion and various aspects of nervous system function, especially the brain. The chapter starts by outlining neuroimaging studies of compassion and then examines the topic of empathy and the brain, noting evidence that observing another person’s emotional state activates parts of the neuronal network that are also involved in processing that same state in oneself. Research suggests that multiple areas within the brain are involved in compassion and compassion training, with some regions more strongly implicated than others. Finally, relevant conclusions are presented and potential directions for future work outlined. Overall, research into the neuroscience of compassion supports the idea that compassion can be cultivated deliberately through training. There is evidence that activities such as compassion training and meditation can increase positive affect, boost resilience, facilitate altruistic behaviour, and possibly even assist with equanimity. These ideas are underpinned by growing neuroscientific evidence of impact on the brain. These valuable findings underscore the importance of developing compassion as a skill and fundamental attribute for healthcare workers across all settings.
Subglacial drainage models, often motivated by the relationship between hydrology and ice flow, sensitively depend on numerous unconstrained parameters. We explore using borehole water-pressure time series to calibrate the uncertain parameters of a popular subglacial drainage model, taking a Bayesian perspective to quantify the uncertainty in parameter estimates and in the calibrated model predictions. To reduce the computation time associated with Markov Chain Monte Carlo sampling, we construct a fast Gaussian process emulator to stand in for the subglacial drainage model. We first carry out a calibration experiment using synthetic observations consisting of model simulations with hidden parameter values as a demonstration of the method. Using real borehole water pressures measured in western Greenland, we find meaningful constraints on four of the eight model parameters and a factor-of-three reduction in uncertainty of the calibrated model predictions. These experiments illustrate Gaussian process-based Bayesian inference as a useful tool for calibration and uncertainty quantification of complex glaciological models using field data. However, significant differences between the calibrated model and the borehole data suggest that structural limitations of the model, rather than poorly constrained parameters or computational cost, remain the most important constraint on subglacial drainage modelling.
Storm Daniel struck northeastern Libya on September 10, 2023, causing severe infrastructure damage and significant human loss. Derna was the most affected city, with the University of Derna suffering extensive damage and the tragic loss of 37 medical students. Medical students face unique psychological and academic stressors, and tend to have higher rates of psychiatric disorders compared to their peers of the same age. This is the first study to investigate the storm’s psychological impact on medical students at the University of Derna. The study has a cross-sectional design and lasted from February 1 to March 1, 2024. We used the Generalized Anxiety Disorder-7 (GAD-7) to assess anxiety and the Patient Health Questionnaire-9 (PHQ-9) to assess depression, along with sociodemographic questions in our questionnaire. We included only active students enrolled in the 7-year undergraduate program at the University of Derna. Statistical tests such as the chi-square test and binary logistic regression were used in the analysis. About 225 students completed the survey. The means and standard deviations for GAD-7 and PHQ-9 scores were 9.2 (3.9) and 10.8 (5.0), respectively. The prevalence of anxiety was 42.2% for cases classified as moderate and severe (cut-off ≥10). Depression had a prevalence of 51.1% for cases classified as moderate, moderately severe and severe (cut-off ≥ 10). Suicidal ideation was reported at a rate of 48.9% for “several days” or more and at 16.5% for “more than half of the days” and “nearly every day.” Internal displacement following the storm was significantly associated with both anxiety (p = 0.033) and depression (p = 0.003). However, age, gender, year of study, monthly allowance and residence status (living with family or alone) did not show a statistically significant association with either anxiety or depression (p > 0.05 for all variables). Logistic regression analysis identified gender as the only significant predictor of anxiety (p = 0.041) and internal displacement as the sole significant predictor of depression (p = 0.023). Medical students at the University of Derna reported high rates of anxiety, depression and suicidal ideation following Storm Daniel. Internal displacement was significantly associated with both anxiety and depression. These results highlight the need for targeted interventions to address medical students’ mental health challenges and improve their overall well-being.
During the 2016 and 2017 fieldwork seasons at the site of Qijiaping in Guanghe County, Gansu Province, China, the team of the Tao River Archaeology Project excavated a large intact kiln. The kiln is well preserved, and the first of its kind reported in an archaeological excavation in this region. Several lines of evidence demonstrate that this was a roof tile kiln used during the Song period (ad 960–1279), possibly associated with the construction and maintenance of defensive facilities during the time of Northern Song (ad 1079–1127) occupation of the region— an era of conflict with the Western Xia (ad 982–1227). Inside the flues of the kiln were many objects disposed of when the kiln was put out of commission. Among these objects is a stone phallus, an object that reflects a gendered aspect of technology and manufacturing associated with this kiln or its decommissioning and more broadly the gendered social landscape of the Tao River valley during the Northern Song occupation of the region.
In April 2023, eighteen scholars from nine different subjects representing the humanities, natural and social sciences came together for a one-day workshop at St John’s College, Durham. Despite our differences, all had one aim: the study of past environmental change and its effects on human societies. Talking across disciplinary divides, we discussed what environmental history is, how it may or may not contribute to tackling the climate crisis, and the problems of sources, scale and temporality. This article collects select conversations into a roundtable format split into four areas: scale, time and space, interdisciplinarity, and the future of environmental history. We argue that environmental history is more usefully understood not as a distinct sub-field of history, but as an interdisciplinary meeting place for innovative collaboration. This also presents a model for future research aimed at tackling the climate crisis at higher education institutions.
This chapter explores why we decided to write this book about compassion in healthcare. Despite choosing our professions in order to help others, many healthcare professionals feel chronically tired, emotionally drained, deeply heart-sore, and ultimately burnt-out. Too often, moments of connection with patients and their families, although magical at the time, also highlight the uncertainties and even the darkness that surrounds them. Commonly, staff struggle to make sense of healthcare systems that seem to value neither ‘health’ nor ‘care’. The message of this book is that we can do better. Perhaps the first step in resolving these matters lies in recognising that while we do not have full control over the shape of the healthcare systems within which we work, or indeed the societies in which we live, we can control how we navigate these contexts, how we respond to them, and how we seek to be in the world. In parallel, we can also seek to change health systems in the direction of more compassionate care. Compassion is always essential in these processes, especially in the settings of health and social care. That is why we wrote this book: to try to make compassionate care a day-to-day clinical reality for everyone: patients, families, and healthcare professionals who constantly seek to do more and better.
To estimate the within-households association between change in income over time and food purchases in a national panel of households. The need to shift towards healthy and sustainable diets is widely recognised, thus the importance of identifying the factors that influence food purchase decisions.
Design:
Longitudinal observational study; for each of the thirty-three food items queried, we ran a conditional logistic fixed-effect regression model to evaluate the association between change in income per-capita and food purchases (yes/no) during the past week, adjusted by covariates.
Setting:
Mexican Family Life Survey.
Participants:
6008 households that participated in the survey for at least two of the three available waves of study (2002, 2005 and 2009).
Results:
Within-households, the OR (95 % CI) of purchasing the food in the past week for an increase in 1 sd of income was 1·09 (1·02, 1·16) for rarer fruits (other than bananas, apples and oranges); 1·11 (1·04, 1·18) for beef; 1·06 (1·00, 1·13) for canned tuna/sardines; 1·09 (1·02, 1·18) for fish/shellfish; 1·08 (1·02, 1·16) for discretionary packaged products and 1·15 (1·08, 1·23) for soft drinks. There were some differences by urban/rural area or socio-economic status (SES); mainly, those with lower SES had increased odds of purchasing the food item in more cases (ten out of thirty-three food items).
Conclusions:
Households’ income growth can have mixed effects on the healthiness and sustainability of food purchases. Public policies to improve the food environment and nutrition education are necessary to enhance the positive and counteract the negative effect of income.