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What factors make aligned relationships possible, and how can we account for transformation of alignments? Alignment patterns and the durability of some aligned relationships above others have often raised questions about factors that influence cooperative arrangements. This article makes a twofold contribution by proposing a tentative process-centred alignment typology as an analytical tool and by empirically applying this tool to examine Sino–Russian alignment (1991–2024). Our conceptual typology differentiates among six primary alignment types: thin strategic partnerships, coalitions, thick strategic partnerships, alliances, non-allied security communities, and allied security communities. We propose that these types become possible due to varying compatibility between prospective or existing alignment partners in their assessment of threats, interpretations of identities, and status expectations. Our empirical analysis focuses on specific upgrades in the Sino–Russian relationship as presented by both states in 1996, 2001, 2011, and 2021 while also discussing more recent developments after Russia’s full-scale invasion of Ukraine.
To examine how artificial intelligence (AI) has been applied to infection prevention and control in healthcare, identify barriers and risks affecting implementation, and develop a structured checklist to support safe adoption.
Design:
Scoping review conducted in line with Joanna Briggs Institute methodology and reported according to PRISMA-ScR.
Methods:
PubMed, Scopus, and Web of Science were searched for primary studies (2014–2024) describing real-world AI applications for IPC. Studies reporting implementation experiences, outcomes, or risks were included. Data on study design, AI type, IPC function, integration level, barriers, and outcomes were extracted and synthesized thematically to derive a 41-item decision-support checklist.
Results:
Of 2,143 records screened, 100 studies met inclusion. Most were published since 2022, with the United States and China leading output. Machine learning dominated (75%), mainly for predictive analytics (53%), HAI detection (13%), and hand hygiene monitoring (13%). Only 15% of tools were integrated into existing digital infrastructures. Barriers centred on data quality (45%), technical and data related (16%), and economic/technical constraints (16%). Reported risks clustered around operational failures (35%), technical errors (33%), and data security (12%). Evidence was heavily skewed toward high-income countries, with limited prospective validation or implementation science.
Conclusions:
AI offers clear promise for IPC, particularly in early detection and compliance monitoring, but its translation into practice remains constrained by data fragmentation, limited integration, and uneven readiness across settings. Our evidence-informed checklist provides IPC teams with a structured tool to assess feasibility, governance, and resource needs before adoption, supporting safer and sustainable innovation.
This article contributes to a growing body of literature on special jurisprudence through a case study of energy law as an emergent area of law that is perceived to lack a clear understanding of its definition, foundations and doctrine. The article has two functions that both seek to integrate the literature on special (as opposed to general) jurisprudence with that on energy law as a legal discipline and an independent area of law. The first is to explain why the lack of a doctrine is a problem for a field like energy law, thus motivating the creation of a special jurisprudence. The second is to outline how the foundations of the discipline could be deliberatively developed in a meaningful and methodologically justified way.
In this paper, I use examples from the Roman past and the Brexit present of the UK to discuss the links between practices, identities and the changing dimensions of imperial power. In both the traditional archaeological context of later Roman Britain and in excavating the roots of Brexit in post-War British politics, analysis of the practical semiotics of identity is the most fruitful way to understand the social processes under way. In each context, the meaning of different practices, articulated through the concepts of identities and boundaries, is crucial to the structuration of, respectively, a late imperial and a post-imperial society. The tensions between imperial and local identities are manifest across a wide suite of practices, the investigation of which provides a dynamic method for understanding how these tensions play out, with consequences for the fragmentation of the Roman Empire, on the one hand, and of the UK, on the other.
Microbial diversity and functions within the Earth’s deep subsurface remain pivotal in the Earth’s major biogeochemical activities. Microbial communities of groundwater systems hosted by ~65-million-year-old Deccan basalts are investigated to delineate their characteristics, biogeochemical functions and environmental control. Quantitative PCR-based bacterial cell counts suggest 4.3 × 102–3.9 × 103 cells/mL. 16S rRNA gene sequence analysis shows considerable bacterial diversity and the existence of a core microbiome (16 amplicon sequence variants [ASVs] out of a total of 2020 ASVs) across the groundwater samples. Members of Burkholderiaceae and Moraxellaceae are predominant taxa within the groundwater. In comparison, the spring water and surface water microbiomes are significantly distinct. Non-metric multidimensional scaling highlights that the basaltic groundwater communities are influenced by local environmental parameters. Analysis of whole metagenomes indicates that the Calvin–Benson–Bassham cycle is a primary mode of carbon fixation in the subsurface water system of the Deccan traps. Metagenome-assembled genomes are affiliated to the genera Limnohabitans and Methylotenera, among others. Together with the presence of sulfate and nitrate in the groundwater environment, the presence of genes involved in dissimilatory nitrate and sulfate reduction indicates the prevalence of anaerobic/facultative anaerobic lifestyles among the microorganisms in this system. Amplicon and whole metagenome sequence-based analyses suggest the presence of microbial populations involved in local biogeochemical cycling. This study on the geomicrobiology of the water systems of Deccan traps elucidates microbial community composition and biogeochemical function in the igneous rock-hosted deep biosphere.
Women in sub-Saharan Africa face complex, multifaceted challenges to their health, including a high burden of infectious diseases aggravated by socioeconomic factors. Parasitic and sexually transmitted infections both cause significant morbidity and mortality. Co-infections compound these effects, leading to high rates of chronic illness and making diagnosis and treatment challenging. There are no integrated approaches for the detection of female genital schistosomiasis (FGS), a gynaecological condition caused by Schistosoma haematobium, and high-risk human papillomavirus (HR-HPV), responsible for over 90% of all cervical cancer cases worldwide. FGS is a chronic condition with health outcomes such as infertility and abortion and remains severely under-reported. HR-HPV infection is the main aetiological agent of cervical cancer, the leading cause of cancer death in women in sub-Saharan Africa. Both can be disabling and stigmatizing to the sufferer. A key to disease management at patient and community levels is accurate and available diagnostics. Due to both FGS and HPV diagnostics utilising cervicovaginal samples, they are ideal candidates for a multiplex molecular diagnostic. The standard molecular diagnostics (namely PCR), through the detection of pathogen DNA, are constrained in low resource settings by requirement of a highly reliable source of energy, reliance on a cold-chain, and prohibitive costs. Isothermal molecular diagnostics are an alternative method to PCR that are more suited to basic settings. This review explores current isothermal diagnostics, with a focus on RPA/RAA, a very simple isothermal technology, for FGS and HPV and proposes the development of a multiplex isothermal diagnostic test to enable integrated screening.
When the nine-year-old Susan Knell wrote to Leonard Bernstein in March 1962 from her family home in Ossining, New York, she had very little — if any — concept of ‘the archive’. Nor were posterity or history-making remotely in her mind. The second child of highly educated Jewish parents, she had been studying the piano because ‘it was something that kids were expected to [do]’.2 Exactly how the letter came about she does not recall. Most likely, one of her parents encouraged her to write to him: ‘They were very impressed by […] famous people who were accomplished’, she reflected. ‘And we were Jewish. And so I think there was that connection with Bernstein.’ Armed with a sheet of lined paper, torn from the pad in such a way that one of the five pre-punched holes was left ripped, she penned her missive. The careful formatting reflected her awareness of ‘good etiquette’, but was also at odds with the childish scrawl, an incongruity suggestive of children’s tendency to do things ‘correctly’, up to a point. Once posted, the letter was sooner or later forgotten by Susan — and likewise was the photograph reportedly sent by return, which she has no memory of ever receiving.3
Developing Consumers: A History of Wants and Needs in Postwar South America offers a comparative social and economic history of South America’s developmental decades, from the 1950s to the mid-1970s. In the aftermath of World War II, Argentina, Brazil, and Chile implemented state-led strategies to secure economic sovereignty, raise living standards, and expand domestic markets. These policies made durable goods such as refrigerators, automobiles, and televisions increasingly available, yet access remained uneven across class, gender, and racial lines. By the 1960s, these commodities had become powerful symbols of modern well-being.
The dissertation examines how people experienced this transformation and how new forms of consumption reshaped ideas of welfare, citizenship, and inequality. By the decade’s end, it was clear that the developmental state could not deliver social mobility or universal access to modern comforts, leading to widespread frustration. Policy makers, marketing experts, and intellectuals debated how to “rationalize” consumption—deciding which needs should be guaranteed for all and which reflected elite privilege.
The global proliferation of Chinese investments has raised national security concerns among many host States. Western economies such as the United States and Australia have strengthened their foreign investment screening (FIS) regimes partially in response to these concerns. Korea and Japan, as representative East Asian economies, have also joined the trend of strengthening FIS regimes to manage security risks associated with foreign investments. This article investigates whether national security has also emerged as a focal point of confrontation between developed East Asian countries and China in international investment landscape. It investigates China’s legal concept of national security and its growing importance in the country’s foreign investment policy. It then examines the FIS regimes in Korea and Japan as well as their practical operations in relation to Chinese investments, with a focus on how national security concerns have shaped their approaches to Chinese investments. This article argues that a national security-focused confrontation has emerged between developed East Asian countries and China in the international investment landscape as a result of their shared national security concerns. Korea and Japan should avoid politicising their FIS regimes in order to prevent potential violations of international investment law and contribute to East Asian economic harmony.
Contingent responses in which caregiver and child build on each other’s positive behavior may attenuate the deleterious effects of early adversity on youth mental health and neuroendocrine functioning. 159 caregiver–child dyads (child age: 6–16 years; 50.9% male; 44.6% adversity-exposed in stable arrangements with adoptive caregivers) participated in a 6-min conflict resolution task, which was coded for second-by-second changes in caregivers’ and children’s behavior (κ’s >0.78). Caregivers reported on their child’s mental health problems; youth hair cortisol concentration was obtained. Caregiver contingent responses to their children (i.e., responding to their partner’s positive social communication with active efforts to facilitate emotion regulation and/or problem-solving) attenuated the effects of adversity on child anxiety and conduct disorder symptoms. Stronger positive child contingent responses to their caregivers attenuated the effects of adversity on child depressive, attention-deficit/hyperactivity disorder symptoms, and oppositional defiant symptoms. Positive contingent transactions are health-promotive interaction sequences that could be targeted in transdiagnostic intervention programs.
Previous research has mainly explored the relationship between bilingual language control and domain-general cognitive control through behavioral correlations, often revealing epiphenomenal links rather than causality. This study utilizes transcranial magnetic stimulation (TMS) to investigate the causal roles of the left inferior frontal gyrus (LIFG) and left middle temporal gyrus (LMTG) in 33 unbalanced Chinese-English bilinguals. Continuous theta burst stimulation was applied in separate sessions to decrease cortical excitability, with vertex stimulation as a control. LIFG stimulation significantly increased switching costs in nonverbal switching tasks, highlighting its role in domain-general cognitive control. LMTG stimulation did not affect switching or mixing costs in language or nonverbal switching tasks, suggesting no causal involvement, but it reduced reaction times (RTs) during language switching tasks, underscoring its specialization in language processing. These findings highlight distinctions between the neural mechanisms of bilingual language control and domain-general cognitive control, particularly in the LIFG.
Shared genetic risk has been shown across psychiatric disorders. In particular, anorexia nervosa (AN), obsessive-compulsive disorder (OCD), and schizophrenia (SCZ) show shared genetic risk that matches clinical evidence of shared illness and cognitive phenotypes. Given this evidence, we leveraged a large US-based population-based study to determine genetic associations of disorder-specific and shared psychiatric, cognitive, and brain markers and explore whether the latter might be state versus trait markers in eating disorders.
Methods
We used data from the population-based Philadelphia Neurodevelopmental Cohort (N = 4,729) and conducted sex-stratified analyses to test for associations between genetic risk for three disorders (AN, OCD, and SCZ) and mental health phenotypes, neurocognitive traits, and cortical features in a non-clinical population. Exploratory analyses on cortical features were run on a subset with neuroimaging data (N = 626).
Results
Genetic risk for AN was significantly associated with body image distortion (pFDR = 0.02), and body image distortion was significantly related to a reduction in grey matter volume (pFDR = 0.05).
Conclusion
Genetic risk for AN associates with AN trait in a non-clinical sample of youth, particularly in females. Whilst genetic risk was not associated with cognitive or cortical markers, the AN phenotype was associated with cortical markers.
Despite repeated calls for action from various sources, peatland archaeological sites continue to deteriorate; the passive strategy of preservation in situ is failing. Here, the authors consider four challenges to peatland preservation—physical degradation, mapping and monitoring of sites, communication, and policy frameworks—with climate change ultimately causing further problems. Drawing on positive policy developments in England, they argue that advocacy for peatland archaeology needs to be louder and clearer: archaeology must become an integral consideration in all climate-change mitigation and land-use planning, rather than an afterthought, if the fragile heritage of European peatlands is to be preserved.
Non-compete clauses (NCCs) are widely used and discussed, but often too narrowly. While conventional accounts focus on the benefits of NCCs to employers, Harrison Frye has proposed that they can also serve employees by acting as a clear, costly signal. I argue that both views rely on an overly narrow analysis. A wider view shows that NCCs cause market failures, undermining their utility as protective or signalling devices. Because of these negative effects, I extend Frye’s account to argue that NCCs should be used only as targeted interventions under exceptional conditions, if they are used at all.
Building on the premise that etiquette (adab-ı muaşeret) is a crucial component in understanding Turkish cultural modernization, this article examines how the Turkish military incorporated Western manners during the Republican era. While the military’s role in supporting Westernization is well documented, less scholarly attention has been paid to the internalization and practice of Western cultural norms, particularly etiquette, within military circles. Conceptualizing manners as a disciplined and refined mode of conduct, this study investigates how Western etiquette was transmitted to military officers and integrated into their personal and professional lives. The article argues that, although military texts on etiquette presented Western manners as essential to social status and modernization, their implementation was characterized by selective adoption, ambiguity, and even resistance. These texts, often compiled by officers themselves, reflect both a desire to assert cultural authority and the complex, negotiated process of Westernization. Drawing on two primary sources – etiquette manuals and officers’ self-narratives – the study illuminates the contested and dynamic nature of adopting Western norms. This dual approach highlights the formation of a cultural identity among officers marked by eclecticism and ambivalence, revealing broader tensions within the Turkish modernization project.
Perry Hendricks (2025) argues that theism is not only compatible with what he calls ‘pointless atheism’ (instances of non-resistant non-belief that do not serve a greater good) but also makes it expected. His case combines the Responsibility Objection (RO) – the view that God permits non-resistant non-belief because it’s required for theists to bear responsibility for bringing others into relationship with God – with a William Hasker-inspired argument concerning motivation and rationality. Hendricks’s core argument can be expressed in two distinct yet interrelated ways: a ‘motivation’ formulation and a ‘rationality’ formulation. I examine each in turn. I argue that, even granting (RO) and the rest of Hendricks’s assumptions, each formulation fails. (RO), together with a few further assumptions to which Hendricks also seems committed, leads to conclusions that undermine rather than support his argument. Thus, we have at least as much reason to reject as to accept his conclusion, and without further clarification and support, his case remains incomplete.
The process of admitting new members to the United Nations has historically been contentious and contradictory. This paper examines new membership through the lens of recognition, focusing on the historical case of Canada’s role in this debate between 1955 and 1962. Canada led the initiative to grant membership to 16 members in 1955 and supported new membership for 17 others (including former French colonies) in 1960. Simultaneously, it opposed resolutions in the UN General Assembly supporting Algerian independence from France . The concept of recognition helps explain this inconsistency, while this case also reveals much about recognition itself. I argue that recognition, both thick and thin, can be multidirectional, in that granting recognition to another state is part of that state’s own struggle for recognition. In 1955 and 1960, Canada granted thin recognition to new members, which had implications for its own struggle for thick recognition. With Algerian independence, this was a debate about thick recognition for Algeria and for France; Canada’s complex struggle for thick recognition also drove its resistance to recognizing Algeria.
Depression severity is a well-established risk factor for suicidal ideation, but the extent to which sociodemographic and employment-related factors contribute independently remains unclear.
Aims
Complete data from doctors (N = 4055) presenting to National Health Service Practitioner Health (NHS-PH) in 2022–2023 were used to test the hypothesis that depression severity is the largest determinant of suicide ideation risk (defined by Patient Health Questionnaire 9 (PHQ-9) question 9 score) among doctors.
Method
Using PHQ-8 score (PHQ-9, excluding the item on suicide ideation) as a proxy for depression severity, the case–control discriminatory capacity of receiver operating characteristic curves (AUCs) were evaluated for (a) a univariable model studying modified PHQ-9 alone as the predictor of severe suicide ideation; and (b) a multivariable model integrating modified PHQ-9 and multiple sociodemographic and employment factors as the predictor of severe suicide ideation. Models were compared both descriptively and through a likelihood ratio test.
Results
The univariable model using depression severity alone as the predictor of severe suicide ideation yielded an AUC of 0.921. The addition of sociodemographic and employment factors improved the fit significantly (likelihood ratio test with (χ2(14) = 50.26, P < 0.001), amended AUC 0.930). Having both a disability and a relationship status of ‘no partner’ was significantly independently associated with suicide ideation in the multivariable model.
Conclusions
In this national cohort of doctors, depression severity was strongly associated with suicidal ideation. However, disability and lack of a partner were also independently linked to increased risk, suggesting that suicidal ideation is not solely driven by symptom severity. Social and functional factors may help identify higher-risk individuals and inform targeted support.