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Not all persons sui iuris with the requisite wealth for municipal office were represented in the local municipal councils. This chapter assesses the prevalence of four different groups of such individuals in early-imperial Italy: the Augustales, male minors and women sui iuris, and persons lacking local citizenship (incolae and attributi).
Difficulties in executive functions (EFs) and internalizing and externalizing problems are prospectively related. However, it remains unclear whether the bidirectional relations between specific EF components and internalizing and externalizing problems at the within-person level vary across developmental stages in childhood and early adolescence.
Methods
This study utilized data from seven waves of the Early Childhood Longitudinal Study, Kindergarten Class of 2010–2011 (ECLS-K: 2011), following a nationally representative sample of 15,055 children (mean age at baseline = 5.63 years, SD = 0.37; age range = 4.02–7.83) from kindergarten through fifth grade. Internalizing and externalizing problems and inhibitory control were assessed using teacher-reported measures, while working memory and cognitive flexibility were evaluated using standardized cognitive tasks. Data were analyzed using a random intercept cross-lagged panel model, adjusting for the complex sampling design.
Results
Working memory negatively predicted internalizing problems from kindergarten to first grade, with no significant link to externalizing problems. Cognitive flexibility showed limited effects, with only spring kindergarten externalizing problems predicting lower cognitive flexibility in first grade. Inhibitory control negatively predicted internalizing problems in early childhood, while internalizing problems positively predicted inhibitory control during the kindergarten-to-first-grade transition. Externalizing problems consistently reduced inhibitory control over time. Notably, inhibitory control negatively predicted externalizing problems until third grade but positively predicted them from third to fourth grade.
Conclusions
The findings suggest that while certain EFs can protect against internalizing and externalizing problems in early childhood, these symptoms may also influence EF development, with these interactions evolving as children transition into adolescence.
Staphylococcus aureus bacteriuria (SABU) may represent bacteremia in a subset of patients. We describe the impact of a microbiology alert recommending follow-up blood cultures (FUBC) for patients with SABU in a large integrated health system.
Methods:
We conducted a quasi-experimental implementation study in adult ambulatory patients with documented SABU. We excluded patients with confirmed SAB up to 14 days prior to index SABU culture and with blood cultures obtained on the day of SABU. The primary outcome was rate of FUBC (collected between 1 and 5 days of SABU) among all cases of SABU. Secondary outcomes included percentage of patients with early SAB (collected between 1 and 5 days of SABU). We used interrupted time series analysis to compare rates of FUBC pre vs postintervention.
Results:
A total of 2 540 patients were identified; 1 213 (48%) were male. By the end of the postintervention period, the rate of FUBC (20.6%) had increased by 6.3 percentage points (P = .005) compared to the counterfactual (14.2%) had no intervention taken place (44.5% relative increase). Early SAB detection due to FUBC increased from .6% preintervention to 2.0% postintervention (P = .004).
Conclusion:
The microbiology alert initiative increased FUBC in patients with SABU by 44%, but the overall rate of FUBC remained low. The intervention increased early SAB detection. Risk-targeted strategies are needed to optimize FUBC collection in patients with SABU.
This article aims to explore the social representations of the Spanish Second Republic and the Transition epochs among university students of various national identities within the Spanish state. A free-association exercise elicited by the words ‘Second Republic’ and ‘Transition’ was completed by 477 university students of the Basque Country, Catalonia, Galicia, and Madrid, who were also asked about their national identity ideological orientation. Lexical analysis was used to analyse their responses. The results demonstrate how these two periods are strongly anchored in the ideological affiliations and social identity of the participants. Furthermore, we observed that the Spanish identity and right-wing ideology were related to a narrative crafted by the political elites during the inception of the current democratic period. Meanwhile, the peripheral national identities and left-wing ideology were associated with a contentious narrative that responds to the contested narrative. In addition, the results also reveal the current relevance of these two periods through their symbols and transmission, whose senses and meanings differ based on the ideological affiliation and national identity of the participants.
This article provides a comparative discussion of the theories of imperialism developed by three prominent scholars – Paul Samuel Reinsch, Ukita Kazutami, and Liang Qichao – in the 1900s. Such a discussion offers a fresh understanding of imperialism in the East Asian context from three perspectives. First, by revealing inter-textual connections between the three figures’ writings, it sheds light on Japan’s mediating role in the formation of Chinese knowledge of imperialism in a transpacific exchange of ideas. Second, it examines how the theories of imperialism travelled in the unequal international spaces created by practices of imperialism. Last, it draws attention to the consequences of embracing the Western ideal of national empire in East Asia, highlighting the fact that some Japanese and Chinese elites resisted Western imperialism on the one hand, but, on the other, drew inspiration from the ideal of imperialism to formulate their own expansionist agendas.
Healthcare-associated infections (HAIs) result in substantial patient harm and avoidable costs. Pay-for-performance programs (PFP) through the Centers for Medicare and Medicaid Services (CMS) have resulted in reductions of HAIs like central line-associated bloodstream infections (CLABSI) and methicillin-resistant Staphylococcus aureus bacteremia, through robust infection prevention programs and practices. Hospital Onset Bacteremia and Fungemia (HOB) is proposed as an alternative quality measure for public reporting and PFP, and was endorsed by the National Quality Forum in 2022. This broad measure is designed as an electronic quality measure that avoids manual abstraction and excludes risk adjustment. HOB would substantially expand the scope of focus of existing bloodstream infection measurement, and is currently being considered for voluntary reporting in 2025. In this article, we provide arguments for and against adopting HOB as a PFP measure linked to CMS payments.
This is a proof-of-concept study to compare the effects of a 2-week program of “Remind-to-move” (RTM) treatment using closed-loop and open-loop wearables for hemiparetic upper extremity in patients with chronic stroke in the community. The RTM open-loop wearable device has been proven in our previous studies to be useful to address the learned nonuse phenomenon of the hemiparetic upper extremity. A closed-loop RTM wearable device, which emits reminding cues according to actual arm use, was developed in this study. A convenience sample of 16 participants with chronic unilateral stroke recruited in the community was engaged in repetitive upper extremity task-specific practice for 2 weeks while wearing either a closed-loop or an open-loop ambulatory RTM wearable device on their affected hand for 3 hrs a day. Evaluations were conducted at pre-/post-intervention and follow-up after 4 weeks using upper extremity motor performance behavioral measures, actual arm use questionnaire, and the kinematic data obtained from the device. Results showed that both open-loop and closed-loop training groups achieved significant gains in all measures at posttest and follow-up evaluations. The closed-loop group showed a more significant improvement in movement frequency, hand functions, and actual arm use than did the open-loop group. Our findings supported the use of closed-loop wearables, which showed greater effects in terms of promoting the hand use of the hemiparetic upper extremity than open-loop wearables among patients with chronic stroke.
This chapter examines the formal relationship between medical professionalism and compassion, looking at codes of ethics and practice guidelines, chiefly for medical professionals but also with reference to other healthcare workers. The chapter starts by exploring the importance accorded to compassion in ethical guidance for doctors in the United Kingdom (UK), Ireland, the United States, Australia, and New Zealand. It then examines guidance specifically aimed at psychiatrists, including documents published by the Royal College of Psychiatrists in the UK, the College of Psychiatrists of Ireland, and the American Psychiatric Association. Many of these guides emphasise the importance of compassion and related values, with the Royal College of Psychiatrists providing particularly detailed suggestions about building and sustaining compassion in mental healthcare. Compassion and related values also feature commonly in codes of practice and ethical guidance for other clinical professionals, such as nurses, midwives, social workers, occupational therapists, and others. This chapter concludes that, taken together, these statements of practice values and ethical principles reflect a welcome and growing emphasis on compassion in guidance for healthcare professionals across many clinical domains.
Ocean submesoscales, flows with characteristic size $10\,\text{m}{-}10\,\text{km}$, are transitional between the larger, rotationally constrained mesoscale and three-dimensional turbulence. In this paper, we present simulations of a submesoscale ocean filament. In our case, the filament is strongly sheared in both vertical and cross-filament directions, and is unstable. Instability indeed dominates the early behaviour with a fast extraction of kinetic energy from the vertically sheared thermal wind. However, the instability that emerges does not exhibit characteristics that match the perhaps expected symmetric or Kelvin–Helmholtz instabilities, and appears to be non-normal in nature. The prominence of the transient response depends on the initial noise, and for large initial noise amplitudes, saturates before symmetric instability normal modes are able to develop. The action of the instability is sufficiently rapid – with energy extraction from the mean flow emerging and peaking within the first inertial period ($\sim\! 18\ \text{h}$) – that the filament does not respond in a geostrophically balanced sense. Instead, at all initial noise levels, it later exhibits vertically sheared near-inertial oscillations with higher amplitude as the initial minimum Richardson number decreases. Horizontal gradients strengthen only briefly as the fronts restratify. These unstable filaments can be generated by strong mixing events at pre-existing stable structures; we also caution against inadvertently triggering this response in idealised studies that start in a very unstable state.
Bubbles entrained by breaking waves rise to the ocean surface, where they cluster before bursting and release droplets into the atmosphere. The ejected drops and dry aerosol particles, left behind after the liquid drop evaporates, affect the radiative balance of the atmosphere and can act as cloud condensation nuclei. The remaining uncertainties surrounding the sea spray emissions function motivate controlled laboratory experiments that directly measure and link collective bursting bubbles and the associated drops and sea salt aerosols. We perform experiments in artificial seawater for a wide range of bubble size distributions, measuring both bulk and surface bubble distributions (measured radii from $30\,\unicode{x03BC} \mathrm{m}$ to $5\,\mathrm{mm}$), together with the associated drop size distribution (salt aerosols and drops of measured radii from $50\,\mathrm{nm}$ to $500\,\unicode{x03BC} \mathrm{m}$) to quantify the link between emitted drops and bursting surface bubbles. We evaluate how well the individual bubble bursting scaling laws describe our data across all scales and demonstrate that the measured drop production by collective bubble bursting can be represented by a single framework integrating individual bursting scaling laws over the various bubble sizes present in our experiments. We show that film drop production by bubbles between $100\,\unicode{x03BC} \mathrm{m}$ and $1\,\mathrm{mm}$ describes the submicron drop production, while jet drop production by bubbles from $30\,\unicode{x03BC} \mathrm{m}$ to $2\,\mathrm{mm}$ describes the production of drops larger than $1\,\unicode{x03BC} \mathrm{m}$. Our work confirms that sea spray emission functions based on individual bursting processes are reasonably accurate as long as the surface bursting bubble size distribution is known.
This chapter contends that Italy was exceptionally wealthy during the Early Empire, both in real and nominal terms. Italy’s prosperity stemmed from several sources: substantial booty, taxes, and rents were diverted from the provinces to the empire’s core; provincial elites engaged in imperial politics were expected to spend lavishly in Rome and its environs; and returns on Italian land were relatively high. Additionally, high prices in Italy for both real estate and commodities augmented Italy’s wealth in nominal terms.
This chapter argues that men with the requisite wealth for political office outside the political orders contributed to the stability of the Roman timocratic political system by serving as a reserve pool from which new magistrates and councillors were recruited. Correspondences between the surpluses of wealthy households at the senatorial, equestrian, and curial levels of the political system, and evidence of shortages of candidates at these levels, substantiate this argument.
We present the results of a theoretical investigation of orbital stability in pilot-wave hydrodynamics, wherein a droplet bounces and self-propels across the surface of a vertically vibrating liquid bath. A critical notion in pilot-wave hydrodynamics is that the bath plays the role of the system memory, recording the history of the droplet in its wave field. Quantised orbital motion may arise when the droplet is confined by either an axisymmetric potential or the Coriolis force induced by system rotation. We here elucidate the dependence of the stability of circular orbits on both the form of the confining force and the system memory. We first provide physical insight by distinguishing between potential- and wave-driven instabilities. We demonstrate that the former are a generic feature of classical orbital dynamics at constant speed, while the latter are peculiar to pilot-wave systems. The wave-driven instabilities are marked by radial perturbations that either grow monotonically or oscillate at an integer multiple of the orbital frequency, in which case they are said to be resonant. Conversely, for potential-driven wobbling, the instability frequency may be resonant or non-resonant according to the form of the applied potential. Asymptotic analysis rationalises the different stability characteristics for linear-spring and Coriolis forces, the two cases that have been explored experimentally. Our results are generalised to consider other potentials of interest in pilot-wave hydrodynamics, and elucidate the distinct roles of wave- and potential-driven instabilities. Our study highlights the limitations of prior heuristic arguments for predicting the onset of orbital instability.
The present paper studies how to encourage longer careers by reducing labor income taxes for older workers. The analysis relies on numerical experiments within a general equilibrium overlapping generations (OLG) model that is calibrated to an average economy of the organisation for economic co-operation and development (OECD). I find that the policy can delay retirement and increase tax revenue and the capital stock if treatment occurs close to, and before, the preferred retirement age. A non-trivial share of the increased post-treatment labor supply can be explained by the substitution of hours worked from the pre-treatment career to the post-treatment career. Lowering the treatment age only leads to small changes in the aggregate labor supply, but is increasingly costly for the government in terms of forgone revenue. Tax shifting toward higher consumption taxes always increases welfare, while tax shifting toward higher capital or labor income taxes paid by younger workers only increases welfare if treatment occurs sufficiently late in the career.
We consider Shimura varieties associated to a unitary group of signature $(n-s,s)$ where n is even. For these varieties, we construct smooth p-adic integral models for $s=1$ and regular p-adic integral models for $s=2$ and $s=3$ over odd primes p which ramify in the imaginary quadratic field with level subgroup at p given by the stabilizer of a $\pi $-modular lattice in the hermitian space. Our construction, which has an explicit moduli-theoretic description, is given by an explicit resolution of a corresponding local model.
Mosquito-borne California serogroup orthobunyaviruses Inkoo (INKV) and Chatanga (CHATV) are known to be endemic in Finland with a high seroprevalence. We developed a novel multiplexed reverse transcription quantitative polymerase chain reaction method for discriminating between the INKV and CHATV. This assay was used along with traditional serological tests to study a set of summertime patients during the years 2021, 2023, and 2024 to assess the epidemiology and prevalence of acute INKV and CHATV infections in Finland. Altogether, 1470 samples were screened, and there were 16 patients who had an acute infection based on serological findings and/or nucleic acid test. The orthobunyavirus-IgG seroprevalences were 18% (2021), 20% (2023), and 30% (2024), being lower than that in studies from 20 years ago. Neutralization tests were carried out, and all but one acute case had more than four-fold higher titre to INVK vs. CHATV, indicating specificity to INKV infection. The results suggest that epidemiology has changed from previous studies, and INKV should be considered a causative agent of summertime infections in Finland. The symptom diversity in mild disease outcomes should be studied to guide orthobunyavirus recognition by clinicians. The use of molecular assay discriminating INKV and CHATV aids in understanding disease associations.
This chapter examines the development of the Italian economy over the first two centuries CE. It re-evaluates two prevalent narratives– declining economic performance and increasing inequality– using proxy data. The evidence indicates that both trends were relatively modest, began only towards the end of this period, and were marked by significant regional and local variation.
Negative symptoms in schizophrenia are critical to functional outcomes but remain difficult to assess reliably. The Brief Negative Symptom Scale (BNSS) was developed to address these challenges, though no validation exists in Romanian-speaking populations. To validate the BNSS in a Romanian clinical sample, explore its psychometric properties and compare BNSS-based and PANSS-based classifications of severe negative symptoms. Forty-seven inpatients with schizophrenia were assessed using Romanian versions of the BNSS, PANSS, CDSS and AIMS. Psychometric analyses included internal consistency, inter-rater reliability, factor analysis and correlation-based validity. Two classification schemes, moderate–severe negative symptoms, measured by BNSS (BNSS-MS), and predominant negative symptoms, measured by PANSS (PANSS-PNS), were compared. The BNSS showed excellent internal consistency (α = .94) and inter-rater reliability (ICC = .98). A five-factor structure was confirmed. BNSS total scores correlated strongly with PANSS negative (ρ = .90), but not with positive, depressive, or motor symptoms. Blunted affect emerged as the most prominent subscale. The BNSS-MS group captured more severe cases than PANSS-PNS and showed greater symptom burden and higher distress scores. The Romanian BNSS is valid and sensitive for detecting negative symptoms, outperforming PANSS in identifying clinically significant subgroups.