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Let ${\mathscr {G}} $ be a special parahoric group scheme of twisted type over the ring of formal power series over $\mathbb {C}$, excluding the absolutely special case of $A^{(2)}_{2\ell }$. Using the methods and results of Zhu, we prove a duality theorem for general ${\mathscr {G}} $: there is a duality between the level one twisted affine Demazure modules and the function rings of certain torus fixed point subschemes in affine Schubert varieties for ${\mathscr {G}} $. Along the way, we also establish the duality theorem for $E_6$. As a consequence, we determine the smooth locus of any affine Schubert variety in the affine Grassmannian of ${\mathscr {G}} $. In particular, this confirms a conjecture of Haines and Richarz.
Refreezing is a critical component of the mass balance of glaciers in Svalbard, yet the processes and changes under a warming climate are not fully understood. Here, we investigate changes in firn properties of the Austfonna ice cap, Svalbard, using a combination of observations and model simulations. We analyze firn stratigraphy and density from five newly retrieved and 11 previously retrieved firn cores, collected at elevations ranging from 506 m a.s.l. to 791 m a.s.l. between 1958 and 2022. All cores exhibit frequent ice layers that indicate persistent refreezing of meltwater; however, no ice slabs (layers exceeding 1 m) were observed. A 13-year-long firn temperature time series from a site near the summit (773 m a.s.l.) shows that annual water percolation reaches depths of 7 m to over 13 m. A notable transition in the firn thermal regime occurred in 2013, transitioning from cold to temperate conditions above the firn-ice interface despite the seasonal cooling occurring in the upper firn layers. Simulations using the CryoGrid community model from 2009 to 2022 corroborate this thermal shift and suggest the development of a firn aquifer multiple times since 2013, with increasing duration and thickness over time.
Recruitment of participants for research is often difficult in primary care, especially children and adolescents. Poor recruitment often leads to extension or discontinuation of randomized controlled trials involving patients. This study describes the impact of media recruitment compared to recruitment via general practitioners (GPs) on characteristics of 152 children aged 7–17 years with functional abdominal pain (FAP) and irritable bowel syndrome. Demographics, clinical and psychosocial characteristics were compared. No clinically relevant differences were found, except for longer pain symptom duration and more diagnoses of FAP in children recruited via media compared to children recruited by their GP. Our results suggest that recruitment via media is effective to recruit children in primary care without inducing relevant baseline characteristic differences and this might decrease research recruitment load for GPs. Subgroup analyses on recruitment method are recommended because recruitment strategy might induce differences in unknown baseline characteristics between groups.
Periodic travelling waves at the free surface of an incompressible inviscid fluid in two dimensions under gravity are numerically computed for an arbitrary vorticity distribution. The fluid domain over one period is conformally mapped from a fixed rectangular one, where the governing equations along with the conformal mapping are solved using a finite-difference scheme. This approach accommodates internal stagnation points, critical layers and overhanging profiles, thereby overcoming limitations of previous studies. The numerical method is validated through comparisons with known solutions for zero and constant vorticity. Novel solutions are presented for affine vorticity functions and a two-layer constant-vorticity scenario.
Bayesian estimates from experimental data can be influenced by highly diffuse or “uninformative” priors. This paper gives examples of how diffuse priors can affect estimates, and discusses how practitioners can use their expertise to critique and select a prior.1
The Cold War is often depicted in binary terms: communists against anti-communists, the left against the right, or the free world versus the communist world. However, during the latter part of the Cold War, particularly following the 1979 war between China and Vietnam, earlier Cold War binaries no longer applied, and new alliances were established. These alliances often brought people with the same enemies together, despite having little in common ideologically. This article examines the historical circumstances and Cold War geographies of ethnic Khmu anti-Lao PDR and anti-Vietnamese insurgents, including their alliances with right-wing governments in Thailand and the communist People’s Republic of China (PRC). As neutralists, these Khmu occupied a political space rarely discussed in relation to the Cold War. Although the PRC provided training, weapons, and supplies to the neutralist Khmu between 1979 and 1983, later their political leader, General Kong Le, had a falling out with the Chinese, and the PRC stopped supporting his largely ethnic minority soldiers. However, up until 1989, the Thai government continued to allow the Khmu to maintain bases in Thailand for launching military operations inside Laos, until the Thai government adopted the “Battlefield to Marketplace” policy. Some Khmu continued resisting inside northwestern Laos during the early 1990s, but with declining numbers of soldiers and decreased outside support, armed resistance ended in 2003. It is critical that the geographies and alliances of the later Cold War be differentiated from those of the earlier years of the Cold War. This transnational insurgency deserves attention.
Children are known to derive more implicatures when the required alternative is made salient through contrast or when it is made contextually relevant through a story or a Question Under Discussion. We investigated the exclusivity implicature of three disjunctions (sau “or”, sau… sau, and fie…fie “either…or”) in child Romanian, an understudied language in the previous literature. Three experiments reveal that the mere presence of the stronger alternative, that is, simply hearing unrelated conjunctive statements in the course of the experiment, is not enough to boost implicatures. Rather, implicatures increase as a result of both access to alternatives and contextual relevance (expressed through conjunctive questions such as Did the hen push the train and the boat?). Interestingly, the boost in implicatures was observed only for sau-based disjunctions, not for fie…fie, which we conjecture may be due to children treating the latter as ambiguous between disjunction and conjunction.
Generation of steady streaming vortices is usually accomplished by mechanically vibrating bodies, as occurs in several microfluidic applications for mixing, as well as for transport and handling of microparticles. Here, we propose the generation of streaming from the harmonic electromagnetic forcing of a free-moving circular magnet held afloat on a shallow electrolytic layer, and show that the sense of rotation of steady vortices is the opposite to that of the classical streaming flow. Reverse streaming is attributed to the coupling between the fluid and the free-moving body. Analytical solutions offer a physical rationale for the observed flow dynamics, while numerical simulation reproduces the experimental observations satisfactorily.
To investigate the association of dietary patterns (DP) with prediabetes and type 2 diabetes (T2D) among Tibetan adults, first to identify DP associated with abdominal obesity and examine their relationships with prediabetes and T2D. Additionally, the study aims to investigate the mediating effects of body fat distribution and altitude on the associations between these DP and the prevalence of prediabetes and T2D.
Design:
An open cohort among Tibetans.
Setting:
Community-based.
Participants:
The survey recruited 1003 participants registered for health check-ups from November to December 2018 and 1611 participants from December 2021 to May 2022. During the baseline and follow-up data collection, 1818 individuals participated in at least one of the two surveys, with 515 of them participating in both.
Results:
Two DP were identified by reduced rank regression. DP1 had high consumption of beef and mutton, non-caloric drink and offal and low intake in tubers and roots, salty snacks, onion and spring onion, fresh fruits, desserts and nuts and seeds; DP2 had high intake of whole grains, Tibetan cheese, light-coloured vegetables and pork and low intake of sugar-sweetened beverages, whole-fat dairy products and poultry. Individuals in the highest tertile of DP1 showed higher risks of prediabetes (OR 95 % CI) 1·35 (1·05, 1·73) and T2D 1·36 (1·05, 1·76). The highest tertile of DP2 exhibited an elevated risk of T2D 1·63 (1·11, 2·40) in full adjustment.
Conclusion:
Abdominal adiposity-related DP are positively associated with T2D. Promoting healthy eating should be considered to prevent T2D among Tibetan adults.
Miocene lacustrine clay deposits formed in the Şile region of Türkiye rest unconformably on Cretaceous andesite, basaltic andesite, basalts and rare dacites. Factors controlling the genesis of this sequence include: (1) sediment provenance, (2) tectonic uplift and climatic regimes during syn- and post-depositional times, (3) burial diagenesis and (4) changes from surface weathering alterations (i.e. oxidation and hydrolysis reactions) in the critical zone. Clay minerals are dominated by kaolinite and illite, with their relative abundances varying in relation to the proximity of coal seams, stratigraphic sequence and in an overlying sand-rich fluvial deposit. Variations in the mineral abundances reveals cyclothem-like sequences with patterns of fining upwards (i.e. increasing clay mineral abundance) capped by thin coal seams. The Clay Mineral Alteration Index values for the Şile clay sequence indicate a slight trend of decreasing chemical weathering intensity up-section, which is consistent with regional geological data for terrain uplifting and a drying climate during the Miocene. Critical zone processes have modified the mineral and chemical assemblages, as evidenced by the appearance of iron oxides putatively formed from recent oxidation of the ferrous minerals siderite and pyrite, which are not found in the upper sections. Taken together, the evidence indicates that the clay minerals are derived from a combination of prior weathering of basement rocks, diagenesis after deposition and modern critical-zone weathering. The degree of each process is dependent on depositional history, stratigraphic position and depth below the land surface, all under the changing influences of tectonic uplift and regional climate. The Şile deposits provide an economical clay resource that could be important to the ceramics industry of Türkiye.
All orthodox believers accept that ‘God’s ways are not our ways’ and that ‘the peace of God passes all understanding’. The sceptical theist tries to apply these principles to the mystery of evil in the world, by arguing that we cannot tell what the divine purpose might be in the sufferings that we cannot explain. There is a danger that an undisciplined putting of evil into the fog of mystery might free our understanding too much from rational constraint. I argue that by combining sceptical theism with the way that Peter van Inwagen deploys the fact of our fallen nature to explain Divine withdrawal, we can give a rational account of the limitations there are on how we can judge God’s justice.
The present study investigated the associations among pre-loss grief, relational closeness, attachment insecurities, continuing bonds (CBs) with the deceased person, and the post-loss adjustment of the caregivers of patients with terminal cancer.
Methods
Data were collected in the hospice department of a cancer center in northern Taiwan; 66 bereaved caregivers completed both pre-loss and post-loss scales. The measures used for the pre-loss phase included the Hogan Grief Reaction Checklist (HGRC; pre-loss version), the Experiences in Close Relationship – Relationship Structures Questionnaire (ECR-RS), and the Inclusion of Other in the Self Scale. The measures used 6–12 months after the death of the patients were the HGRC (post-loss version) and the Continuing Bond Scale (CBS).
Results
Pre-loss grief and externalized CBs had a significant impact on the amount of post-loss grief, indicating that pre-loss grief and ongoing transformation of relationships after patients’ death may be predictors of caregivers’ post-loss grieving.
Significance of results
This longitudinal study provides preliminary evidence that pre-loss grief and the relationship with the patient are key to caregivers’ post-loss adjustment, suggesting that psychosocial intervention focuses on caregivers’ pre-loss grief and relationship quality with the patient during palliative care.
On October 3–4, 2023 and September 30–October 1, 2024, the Memorial Sloan Kettering Cancer Center Department of Psychiatry and Behavioral Sciences and Supportive Care Service hosted the 4th and 5th Annual U.S. Celebration of World Hospice and Palliative Care Day (WHPCD) conferences, respectively. This article describes both events and lessons learned in anticipation of the 6th annual conference to be held October 6–7, 2025.
Methods
The 4th and 5th annual events, conference planning team reflection, and attendee evaluation responses are summarized.
Results
Since 2020, the conference has attracted attendees from around the world. Two primary aims continue to guide the event: community building and wisdom sharing at the intersection of art and science. Both the 2023 and 2024 events consisted of 13 unique interactive sessions addressing diverse hospice and palliative care topics delivered by interprofessional experts in palliative care (43 faculty in 2023 and 54 in 2024). Multidisciplinary registrants more than doubled from 764 in 43 countries (2023) to 1678 in 87 countries (2024). Complimentary registration for colleagues in low- and middle-income countries (LMIC), students and trainees, and individuals experiencing financial hardship remains a cornerstone of inclusion and equitable access to the event.
Significance of results
The U.S. WHPCD Conference provides a virtual platform to disseminate high-quality science, honor both clinician and patient and caregiver experiences, and celebrate hospice and palliative care delivery during substantial local and global change across practice and policy domains. We remain committed to ensuring an internationally relevant, culturally diverse, and multidisciplinary and interprofessional agenda that will draw increased participation worldwide during future annual events.
Cross-gender behaviour gradually entered the spheres of aetiology and diagnosis during the eighteenth century with reference to scattered instances of male cross-dressing. But well into the nineteenth century, “gender identity” (a mid-twentieth-century term) remained a poorly theorised instance of medicalisation. Late eighteenth-century concepts of “dynamic hermaphroditism” accounted for gender-nonconforming behaviours and aspirations, but could not account for the observed heterogeneity in disparities between sexed body and mind. Increasingly substantive contributions to aetiology were seen during the late 1870s and 1880s, particularly in response to Carl Westphal’s convoluted, 1869 concept of “contrary sexual feeling” (conträre Sexualempfindung). Richard von Krafft-Ebing’s notion of metamorphosis sexualis paranoica provided one of the most authoritative approaches to the question of gender identification in “sexual inversion”. The notion, which took the first seven German editions of his Psychopathis sexualis to achieve a definitive formulation, needs to be seen in light of Krafft-Ebing’s earlier conceptions of sexual delusion, which straddled the realms of the experienced sexual body and sense of self. Moreover, Krafft-Ebing was not the first to outline a theory of non-cisgender identity, as demonstrated by the mid-1880s work of Théodule-Armand Ribot and Rudolph Arndt, as well as various significantly earlier approaches to what had been considered the “monomania of sexual transformation”.
The presence of multi-component protons with their distinct features is confirmed by various space missions in the Earth’s outer magnetosphere regions. Isotropic cold protons and anisotropic hot protons significantly influence/modify the dispersion behaviour of various modes and instabilities and regulate the magnetospheric dynamics effectively. Our present study pays attention to the left-hand-polarised proton cyclotron mode, which gets unstable in the large proton temperature anisotropy condition, i.e. $T_{\perp p}\gt T_{\parallel p}$. Such favourable thermal conditions for protons are extensively observed during the compression of the solar wind against the Earth’s magnetic field. To reveal the wave dynamics in more detail, i.e. time-scale variations in the cold and hot proton temperatures and resulting wave-energy density, we further allow the time evolution of our model bi-Maxwellian distribution function in response to the proton cyclotron instability. Based on velocity-moment techniques, we formulated a set of equations comprising an instantaneous dispersion relation, dynamical perpendicular and parallel temperature relations and a wave-energy density equation. For the graphical illustrations of our mathematical results, we choose initial conditions that are relevant to magnetospheric space environments and reported in various experimental studies. Our exact numerical analysis shows the notable impact of hot proton temperature anisotropy and relative density on the real frequency, growth rate, evolution of initial distributions and wave-energy density of the proton cyclotron instability. Such detailed outcomes will be quite helpful for global/local magnetospheric experimental and simulation studies.
To investigate associations between dietary intake and patterns of food preparation by age group.
Design:
This cross-sectional study analysed dietary intake data from the most recent Portuguese National Food, Nutrition and Physical Activity Survey. Cluster analysis categorised dietary intake based on the source of food preparation. Regression models were used to study the association between dietary daily intake, Healthy Eating Score (HES) and patterns of food preparation.
Setting:
Portugal, using data representative of the Portuguese population.
Participants:
A total of 5005 Portuguese residents aged 3–84 years were included in the analysis. Dietary intake and food preparation patterns were examined by age group.
Results:
The predominant pattern of food preparation was food prepared by restaurants, canteens and other away-from-home establishments (45·9 %, 95 % CI = 43·8, 48·1). Children and adolescents in this pattern had significantly higher intakes of energy and carbohydrates but lower protein intake compared with those consuming predominantly home-prepared foods. Among adults and the elderly, this pattern was associated with higher intakes of energy, saturated fats, trans fats and free sugars and lower fibre intake. Additionally, children and adolescents whose diets predominantly included food prepared away-from-home showed a decrease in HES (β = –0·7, 95 % CI = –1·3, –0·2), and adults experienced a greater reduction (β = –1·2, 95 % CI = –1·5, –0·9).
Conclusions:
In Portugal, consuming food prepared away from home is associated with poorer dietary quality, with higher energy and unhealthy nutrient intake and lower HES, suggesting a need for interventions focused on promoting healthier food preparation practices.
The shear Alfvén wave (SAW) continuum plays a critical role in the stability of energetic particle-driven Alfvén eigenmodes. We develop a theoretical framework to analyze the SAW continuum in three-dimensional (3-D) quasisymmetric magnetic fields, focusing on its implications for stellarator design. By employing a near-axis model and degenerate perturbation theory, the continuum equation is solved, highlighting unique features in 3-D configurations, such as the interactions between spectral gaps. Numerical examples validate the theory, demonstrating the impact of flux-surface shaping and quasisymmetric field properties on continuum structure. The results provide insights into optimizing stellarator configurations to minimize resonance-driven losses of energetic particles. This work establishes a basis for incorporating Alfvénic stability considerations into the stellarator design process, demonstrated through optimization of a quasihelical configuration to avoid high-frequency spectral gaps.
Despite consensus that quality of life (QoL) in later adulthood is multi-dimensional, scholars’ perceptions of the dimensions the construct comprises differ. Under the premise that models and measures of QoL should correspond with lay perspectives to have relevance to the targeted population, we investigated the constituents of QoL in later adulthood as perceived by middle-aged and older laypersons. We fielded a factorial design vignette experiment among 2,544 respondents aged 50+ participating in the Dutch Longitudinal Internet studies for the Social Sciences panel to assess how 11 dimensions identified from four established QoL instruments designed for older people (WHOQOL-OLD, CASP-19, OPQOL, ICECAP-O) influence QoL evaluations. The study extends prior work on lay perspectives on QoL by combining the internal validity of an experiment with the external validity of a true population sample. All dimensions considered significantly impacted the QoL ratings in the expected direction. Enjoyment and social participation had a significantly larger contribution than the other dimensions. Models stratified by age group showed a strong degree of similarity, suggesting a high level of consensus across age groups about the constituents of QoL in later adulthood. The study highlights the necessity of capturing a broad range of dimensions when conceptualizing QoL in later adulthood. Our finding that dimensions that were omitted in selected established instruments still contributed substantially to QoL evaluations arguably implies that these instruments may have suboptimal content validity. The insights gained from this study are important for developing and evaluating policies aimed at improving QoL for the ageing population.
Indaziflam (Rejuvra®), a preemergence herbicide first registered in vine and tree nut crops, was recently approved for applications to rangeland for winter annual grass control. Indaziflam controls cheatgrass (Bromus tectorum L.) for at least 3 yr, and control can extend into a fourth and fifth year; however, it is very difficult to find indaziflam residues in the soil 2 yr after application. Indaziflam could be absorbed by seeds still retained on the plant and on the soil surface in sufficient concentrations to stop establishment. To test this hypothesis, B. tectorum seeds and jointed goatgrass (Aegilops cylindrica Host) spikelets were treated with indaziflam and imazapic at rates from 5.4 to 175 g ai ha−1 using a greenhouse track sprayer delivering 187 L ha−1. Treated seeds were planted into field soil, and plants were allowed to grow for 21 d under greenhouse conditions. Growth was compared with growth of non-treated controls. In addition, a second set of treated seeds were exposed to rainfall 1 and 24 h after treatment and rainfall amounts ranging from 3 to 24 mm to determine whether rainfall impacted herbicide performance. Bromus tectorum was so sensitive to indaziflam that establishment was eliminated at all rates. Imazapic inhibited B. tectorum establishment with an ED90 of 67 g ai ha−1. Indaziflam effectively inhibits A. cylindrica establishment with an ED90 of 7.4 g ai ha−1 compared with imazapic with an ED50 of 175 g ai ha−1. Indaziflam’s impact on A. cylindrica establishment was not significantly impacted by rainfall, indicating that the herbicide was absorbed to the seed coat. These findings support the hypothesis that indaziflam’s long-term control could result from its ability to inhibit establishment of seeds retained in the canopy and those on the soil surface at the time of application.