The 2007 adoption of the United Nations Declaration on the Rights of Indigenous Peoples (UNDRIP) marked a critical juncture in the area of Indigenous rights. As a nonbinding agreement, its adoption is at the discretion of each state, resulting in significant state-level variation. Importantly, within-state variations remain underexplored. These differences are potentially significant in federal, decentralized countries such as Canada. This article examines why some provinces and territories lead in implementing the key principles embedded in UNDRIP, whereas others have dragged their feet. We collected 230 Canadian regulations introduced at the subnational level between 2007 and 2023, and assessed the impact of three key variables (i.e. political ideology, resource politics and issue voting). We found that none of these variables explained within-state variations on their own. To further explore the role of these variables, we subsequently compared two provinces at different stages of the UNDRIP implementation spectrum (Québec and British Columbia).

Plusieurs personnes atteintes d’un cancer incurable sont des hommes, âgés de plus de 65 ans. Même si, à notre connaissance, aucune recherche ne porte sur les souffrances de ces hommes, des écrits dévoilent que ces dernières pourraient être considérables. Les réalités du vieillissement au masculin couplées à celles d’être atteint d’une maladie incurable peuvent effectivement engendrer des souffrances particulières. Cette recherche qualitative vise à mieux comprendre les souffrances vécues par les hommes âgés atteints d’un cancer incurable (HACI). Nous explorerons si et comment leurs souffrances se rapportent à des enjeux identitaires de genre et/ou aux transformations de leurs rôles. Dix-sept hommes âgés de 65 ans et plus atteints d’un cancer incurable furent rencontrés en milieu urbain (Montréal) dans le cadre d’entretiens semi-dirigés. L’analyse thématique des résultats a permis de relever des enjeux identitaires et de rôles, la nature des changements affectant l’identité et ses rôles et les enjeux de genre vécus par les HACI.

Daytime sleepiness and fatigue are prominent symptoms of myotonic dystrophy type 1 (DM1) that can be amenable to treatment in the context of randomized controlled trials. No study has yet documented whether self-reported measures of daytime sleepiness and fatigue can detect change over time and the meaning of this change. The aim was to explore indicators of responsiveness to change and interpretability for the Daytime Sleepiness Scale and the Fatigue Severity Scale in 115 DM1 prospectively followed patients. Results suggest that these two self-reported questionnaires are sufficiently sensitive to detect changes beyond expected measurement error over time in this population.

Labelling resettlement programs as voluntary suggests that they cause little contention and are devoid of coercion. But is this representation accurate? Drawing on unpublished government documents and media reports, we provide a detailed case study of the Community Relocation Policy (CRP) of Newfoundland and Labrador (NL) from 2009 to the present. We show that CRP has been fraught with contention due to the nature of the voting process and the slow and uncertain nature of the community-oriented consultative process. This article highlights the ways in which coercion has emerged from within the very communities considering resettlement, in addition to any coercion that might come from government officials.

Challenging conventional wisdom, this article argues that Indonesia — long home to both large-scale transmigration programmes and a range of conflicts — has not witnessed transmigrant conflicts. The vast majority of Indonesian transmigrants were resettled in parts of Sumatra which have remained peaceful. In some conflicts, the role of transmigration has been exaggerated. In others, interethnic violence has involved spontaneous migrants rather than state-led transmigrants. We conclude with a discussion of two potential outliers, where violence has been directed towards transmigrants, but only those from disaster-affected regions who arrived en masse. This article argues for a more nuanced understanding of the distinctions between different forms of internal migration, some of which have the potential to spark future violence in recipient areas and communities.

The aim of the present study was to identify molecular mechanisms involved in liver fat and cholesterol accumulation in ovariectomised (Ovx) rats fed with high-cholesterol diets. VLDL assembly and bile acid metabolism were specifically targeted. After being either Ovx or sham-operated, the rats were fed a standard diet or a high-fat diet containing 0, 0·25 or 0·5 % cholesterol for 6 weeks. Although Ovx rats exposed to dietary cholesterol intake accumulated the greatest amount of hepatic fat and cholesterol, plasma cholesterol levels were lower (P< 0·05) in these animals than in the corresponding control rats. Accompanying this observation, ovariectomy and dietary cholesterol intake resulted in a down-regulation (P< 0·05) of the expression of genes associated with VLDL assembly, including microsomal TAG transfer protein, diacylglycerol acyltransferase 2, acyl-CoA:cholesterol acyltransferase 2 and apoB-100 as well as genes associated with bile acid metabolism including farnesoid X receptor and bile salt export pump (P< 0·01). These results indicate that high-fat/high-cholesterol diets and ovariectomy concomitantly disrupt hepatic lipid output through defects in VLDL assembly and, most probably, secretion. The results also point to a defect in hepatic bile acid secretion. The present study offers novel insights into intrahepatic lipid metabolism, which may be relevant to metabolic complications found in postmenopausal women.

Social networking sites have recently garnered academic attention for their role in fostering democracy and openness in both developed and developing regions. Unfortunately, in political science, this newfound interest has not yet translated into a greater interest in social media as a methodological tool for researchers conducting fieldwork. How has the era of social media influenced the way political scientists conduct their fieldwork? How can researchers make the most of the opportunities offered by social networking sites while abiding by the strict standards of their ethics board? This article highlights the potential in social networking sites for recruiting participants and gathering data and looks at the impact sites such as Facebook have had on building and maintaining trust with research participants. In contrast, it explores how social media may compromise one's ability to uphold the “do no harm” principle guiding all academic research by jeopardizing participants' confidentiality and anonymity, a risk deemed especially high for vulnerable populations or sensitive regions. Insight gleaned from the researcher's own fieldwork in two minority provinces of Indonesia in 2010–2011 is used as a case in point.

Herbivory is one of the most important biological processes influencing coral reefs. In the highly diverse Indo-Pacific reef fish communities, different herbivores can have strikingly different functions. We investigated the extent of functional diversity among herbivorous parrotfish of the more species-depauperate Caribbean Sea. We carried out observations of seven species of parrotfish (Scarus taeniopterus, Sc. vetula, Sc. iserti, Sparisoma viride, Sp. aurofrenatum, Sp. rubripinne and Sp. chrysopterum) on four Barbadian coral reefs to collect information on foraging techniques, rates, and targets, and found marked interspecific variation. Species of the genus Scarus had higher foraging rates than those of the genus Sparisoma. Different species took varying amounts of live coral, turf algae and macroalgae. A functional categorization based first on foraging technique (contact or no contact with the substratum) and secondarily on the more conventional criterion of foraging target (macroalgae, turf algae and live coral) allowed us to classify Sc. taeniopterus and Sc. iserti as ‘scrapers’, Sp. aurofrenatum, Sp. rubripinne and Sp. chrysopterum as ‘grazers’, Sp. viride as a ‘bioeroder’ and Sc. vetula as a ‘bioeroder/scraper’. This functional group affiliation, together with species-specific foraging rates, allows us to predict the role of Caribbean parrotfish on major coral reef processes and their impact on coral reef benthic communities.