We use cookies to distinguish you from other users and to provide you with a better experience on our websites. Close this message to accept cookies or find out how to manage your cookie settings.
To save content items to your account,
please confirm that you agree to abide by our usage policies.
If this is the first time you use this feature, you will be asked to authorise Cambridge Core to connect with your account.
Find out more about saving content to .
To save content items to your Kindle, first ensure no-reply@cambridge.org
is added to your Approved Personal Document E-mail List under your Personal Document Settings
on the Manage Your Content and Devices page of your Amazon account. Then enter the ‘name’ part
of your Kindle email address below.
Find out more about saving to your Kindle.
Note you can select to save to either the @free.kindle.com or @kindle.com variations.
‘@free.kindle.com’ emails are free but can only be saved to your device when it is connected to wi-fi.
‘@kindle.com’ emails can be delivered even when you are not connected to wi-fi, but note that service fees apply.
The objective of our paper is to provide an explanation for the lack of joint adoption by farmers of cleaner technologies in banana production, specifically fallow period (FP) and disease-free seedlings (DFS). Our hypothesis is that while these technologies are synergistic from an agronomic and environmental perspective, and thus efficient from a social interest perspective, they are substitutable rather than complementary from a farmer’s private interest perspective. In other words, farmers receive lower returns from adopting both technologies together than from adopting them in isolation. To test this hypothesis, we present a unified empirical framework for assessing complementarity. We estimate a structural model of complementarity that overcomes the unobservable heterogeneity bias found in previous models using a database of 607 banana farmers in the French West Indies. Our results support our hypothesis, showing a substitution effect between FP and DFS rather than a complementarity effect. Moreover, we observe a contrasting profile of adopting farmers: smallholders who are reluctant to change adopt FP, while more specialized farmers who anticipate a pesticide ban adopt DFS. A public policy that promotes joint adoption should compensate smallholders for the cost of the DFS technology, while compensating more productive farmers for leaving their land fallow.
Les élections municipales de 2021 à la Ville de Québec ont été marquées par une forte compétition entre cinq candidats et une saillance des enjeux concernant la construction d'un tramway et d'un troisième lien autoroutier entre Québec et sa Rive-Sud. Ainsi, cette élection représente un contexte idéal pour étudier le comportement électoral au niveau local et plus spécifiquement le vote sur enjeu qui a été très peu étudié dans le contexte municipal. Nous soutenons que ces deux enjeux ont acquis une valeur symbolique et ont été exploités comme enjeu de brèche par le candidat à la mairie Jean-François Gosselin. À l'aide d'une analyse multivariée, nous testons la relation entre l'appui aux deux projets de transport et l'intention de vote. Nos résultats montrent que les attitudes des électeurs envers ces deux enjeux sont fortement corrélées avec leur choix de vote et suggèrent une continuité entre le comportement électoral municipal, provincial et fédéral, du moins lorsqu'il est question de vote sur les enjeux.
Environment has long been known to have an impact on the evolution of galaxies, but disentangling its impact from mass evolution requires the careful analysis of statistically significant samples. By implementing cutting-edge visualisation methods to test and validate group-finding algorithms, we utilise a mass-complete sample of galaxies to $z \lt 0.1$ comprised of spectroscopic redshifts from prominent surveys such as the 2-degree Field Galaxy Redshift Survey and the Galaxy and Mass Assembly Survey. Utilising our group finding methods, we find 1 413 galaxy groups made up of 8 990 galaxies corresponding to 36% of galaxies associated with group environments. We also search for close pairs, with separations of $r_\mathrm{sep} \lt 50$$\text{h}^{-1}\text{kpc}$ and $v_\mathrm{sep} \lt 500 \: \text{km s}^{-1}$ within our sample and further classified them into major ($M_{sec}/M_{prim} \leq$ 0.25) and minor ($M_{sec}/M_{prim} \gt $ 0.25) pairs. To examine the impact of environmental factors, we employ bespoke WISE photometry, which facilitates accurate measurements of stellar mass and star formation rates and hence the best possible description of the variation of galaxy properties as a function of the local environment. Our analysis, employing a derived star-forming main sequence relation, reveals that star-formation (SF) within galaxies are pre-processed as a function of group membership. This is evident from the evolution of the star-forming and quenched population of galaxies. We see an increase in the fraction of quiescent galaxies relative to the field as group membership increases, and this excess of quenched galaxies relative to the field is later quantified through the use of the environmental quenching efficiency ($\varepsilon_{env}$) metric. Within the star-forming population, we observe SF pre-processing with the relative difference in specific star formation rates ($\Delta sSFR$), where we see a net decrease in SF as group membership increases, particularly at larger stellar masses. We again quantify this change within the SF population with our star formation deficiency ($\varepsilon_{SFD}$) metric. Our sample of close pairs at low stellar masses exhibit enhanced star formation efficiencies compared to the field, and at larger stellar mass ranges show large deficiencies. Separating the close pairs into major/minors and primary/secondaries reveals SF enhancements projected separation decreases within the minor pairs, this effect is even more pronounced within minor primaries. This research emphasises the importance of carefully studying the properties of galaxies within group environments to better understand the pre-processing of SF within galaxies. Our results show that the small-scale environments of galaxies influence star-forming properties even when stellar masses are kept constant. This demonstrates that galaxies do not evolve in isolation over cosmic time but are shaped by a complex interaction between their internal dynamics and external influences.
The sea urchin Arbacia spatuligera is an echinoid distributed in the Southeastern Pacific Ocean from Peru to Chile. This species was previously reported from the subtidal zone with a bathymetric distribution up to 30 m depth. In this work, 128 individuals were found in four mesophotic reefs along the central coast off Chile using closed-circuit rebreathers in technical diving at higher depths than previously, ranging from 36 to 63 m in depth. A population exhibits unexpected morphological characters, requiring an emended diagnosis and description of a new morphotype for A. spatuligera. These morphological traits are further discussed as potential ecophenotypic adaptations.
In situ elemental imaging of planetary surface regolith at a spatial resolution of 100s to 1000s of microns can provide evidence of the provenance of rocks or sediments and their habitability, and can identify post-depositional diagenetic alteration affecting preservation. We use high-resolution elemental maps and XRF spectra from MapX, a flight prototype in situ X-ray imaging instrument, to demonstrate this technology in rock types relevant to astrobiology. Examples are given for various petrologies and depositional/diagenetic environments, including ultramafic/mafic rocks, serpentinites, hydrothermal carbonates, evaporites, stromatolitic cherts and diagenetic concretions.
Psychotic experiences (PEs) and social isolation (SI) seem related during early stages of psychosis, but the temporal dynamics between the two are not clear. Literature so far suggests a self-perpetuating cycle wherein momentary increases in PEs lead to social withdrawal, which, subsequently, triggers PEs at a next point in time, especially when SI is associated with increased distress. The current study investigated the daily-life temporal associations between SI and PEs, as well as the role of SI-related and general affective distress in individuals at clinical high risk (CHR) for psychosis.
Methods
We used experience sampling methodology in a sample of 137 CHR participants. We analyzed the association between SI, PEs, and distress using time-lagged linear mixed-effects models.
Results
SI did not predict next-moment fluctuations in PEs, or vice versa. Furthermore, although SI-related distress was not predictive of subsequent PEs, general affective distress during SI was a robust predictor of next-moment PEs.
Conclusions
Our results suggest that SI and PEs are not directly related on a moment-to-moment level, but a negative emotional state when alone does contribute to the risk of PEs. These findings highlight the role of affective wellbeing during early-stage psychosis development.
Understanding the dynamics of snow avalanches is crucial for predicting their destructive potential and mobility. To gain insight into avalanche dynamics at a particle level, the AvaNode in-flow sensor system was developed. These synthetic particles, equipped with advanced and affordable sensors such as an inertial measurement unit (IMU) and global navigation satellite system (GNSS), travel with the avalanche flow. This study focuses on assessing the feasibility of the in-flow measurement systems. The experiments were conducted during the winter seasons of 2021–2023, both in static snow cover and dynamic avalanche conditions of medium-sized events. Radar measurements were used in conjunction with the particle trajectories and velocities to understand the behaviour of the entire avalanche flow. The dynamic avalanche experiments allowed to identify three distinct particle flow states: (I) initial rapid acceleration, (II) a steady state flow with the highest velocities (9–17 ms−1), and (III) a longer deceleration state accompanied by the largest measured rotation rates. The particles tend to travel towards the tail of the avalanche and reach lower velocities compared to the frontal approach velocities deduced from radar measurements (ranging between 23–28 ms−1). The presented data give a first insight in avalanche particle measurements.
Understanding the distribution and extent of suitable habitats is critical for the conservation of endangered and endemic taxa. Such knowledge is limited for many Central African species, including the rare and globally threatened Grey-necked Picathartes Picathartes oreas, one of only two species in the family Picathartidae endemic to the forests of Central Africa. Despite growing concerns about land-use change resulting in fragmentation and loss of forest cover in the region, neither the extent of suitable habitat nor the potential species’ distribution is well known. We combine 339 (new and historical) occurrence records of Grey-necked Picathartes with environmental variables to model the potential global distribution. We used a Maximum Entropy modelling approach that accounted for sampling bias. Our model suggests that Grey-necked Picathartes distribution is strongly associated with steeper slopes and high levels of forest cover, while bioclimatic, vegetation health, and habitat condition variables were all excluded from the final model. We predicted 17,327 km2 of suitable habitat for the species, of which only 2,490 km2 (14.4%) are within protected areas where conservation designations are strictly enforced. These findings show a smaller global distribution of predicted suitable habitat forthe Grey-necked Picathartes than previously thought. This work provides evidence to inform a revision of the International Union for Conservation of Nature (IUCN) Red List status, and may warrant upgrading the status of the species from “Near Threatened” to “Vulnerable”.
Personality has been identified as a possible antecedent to emotions experienced in the foreign language (FL) classroom. However, contrasting results and differing personality models have resulted in ambiguous findings. This study set out to delve deeper into the role of personality as a predictor of FL emotions through a series of increasingly restrictive statistical models on a sample of n = 246 FL learners. The relationships between personality—operationalized as global and lower order factors in the five factor model—and the FL emotions of Foreign Language Enjoyment, Anxiety, and Boredom were examined. The global factors of Neuroticism, Extraversion, and Conscientiousness, and the lower order factors of Trust, Dutifulness, and Cheerfulness were significant predictors of FL emotions. However, the complexity of personality as a predictor variable is demonstrated in the intricacy of the results and as such the inclusion of personality in explanatory models of FL emotions ought to be approached with caution.
There is limited information on the volume of antibiotic prescribing that is influenza-associated, resulting from influenza infections and their complications (such as streptococcal pharyngitis). We estimated that for the Kaiser Permanente Northern California population during 2010–2018, 3.4% (2.8%–4%) of all macrolide prescriptions (fills), 2.7% (2.3%–3.2%) of all aminopenicillin prescriptions, 3.1% (2.4%–3.9%) of all 3rd generation cephalosporins prescriptions, 2.2% (1.8%–2.6%) of all protected aminopenicillin prescriptions and 1.3% (1%–1.6%) of all quinolone prescriptions were influenza-associated. The corresponding proportions were higher for select age groups, e.g. 4.3% of macrolide prescribing in ages over 50 years, 5.1% (3.3%–6.8%) of aminopenicillin prescribing in ages 5–17 years and 3.3% (1.9%–4.6%) in ages <5 years was influenza-associated. The relative contribution of influenza to antibiotic prescribing for respiratory diagnoses without a bacterial indication in ages over 5 years was higher than the corresponding relative contribution to prescribing for all diagnoses. Our results suggest a modest benefit of increasing influenza vaccination coverage for reducing prescribing for the five studied antibiotic classes, particularly for macrolides in ages over 50 years and aminopenicillins in ages <18 years, and the potential benefit of other measures to reduce unnecessary antibiotic prescribing for respiratory diagnoses with no bacterial indication, both of which may contribute to the mitigation of antimicrobial resistance.
Cassava flour is the main source of carbohydrates for family farmers in the Amazon region of Brazil. Cassava is mainly grown under shifting cultivation, in recurrent cultivation periods initiated through slash-and-burn. Its sustainability is, however, questioned due to the associated deforestation and often rapidly decreasing crop productivity. There is an urgent need to make these cassava systems more sustainable and more profitable, but we currently lack a deep understanding of the key factors governing their productivity. We conducted an on-farm study on 37 cassava fields of smallholder farmers at three locations that spanned a range of crop-fallow frequencies, some of which were initiated through slash-and-burn while others through fire-free land clearance. First, we analysed how cassava plant density at harvest was related with pedoclimatic and management factors in slash-and-burn systems. Second, we assessed the relationship between plant density and cassava root yield at harvest and conducted a yield gap analysis to better understand which factors govern cassava productivity beyond plant density in slash-and-burn systems. Finally, we compared cassava productivity between slash-and-burn and the fire-free land clearing techniques that some farmers started to adopt in the study region. Cassava yields averaged 7.2 ± 5.4 Mg ha–1 (50% of the average yield of 14.2 Mg ha–1 in the Pará State), and ranged from 0 (in case of root rot diseases) to 24 Mg ha–1. Cassava yield was associated with plant density at harvest (ranging from 0 to 10 000 plants ha–1), suggesting that managing plant density is a key determinant of the attainable yield levels. In addition, differences in cassava root yields could be largely explained by differences in labour inputs for weeding and fallow clearing, the effect of the latter depending on soil texture. Therefore, our results suggest that labour is a key production factor for cassava in the shifting cultivation systems of the Eastern Amazon in which the use of external inputs, such as chemical fertilizers and herbicides, is limited. Further, root yields were influenced by the method of field preparation, whereby yields were about 50% lower (and more variable) when fields were prepared by slash-and-burn than by mechanical ploughing or herbicide application. Despite the significantly higher yields, these alternatives to burning the vegetation are, however, still hardly adopted in Paragominas. Hence, there is a need for supporting more sustainable production systems through local and national public policies. These new systems should not only focus on soil fertility management but also on weed control and, more generally, on labour productivity.
This article is a clinical guide which discusses the “state-of-the-art” usage of the classic monoamine oxidase inhibitor (MAOI) antidepressants (phenelzine, tranylcypromine, and isocarboxazid) in modern psychiatric practice. The guide is for all clinicians, including those who may not be experienced MAOI prescribers. It discusses indications, drug-drug interactions, side-effect management, and the safety of various augmentation strategies. There is a clear and broad consensus (more than 70 international expert endorsers), based on 6 decades of experience, for the recommendations herein exposited. They are based on empirical evidence and expert opinion—this guide is presented as a new specialist-consensus standard. The guide provides practical clinical advice, and is the basis for the rational use of these drugs, particularly because it improves and updates knowledge, and corrects the various misconceptions that have hitherto been prominent in the literature, partly due to insufficient knowledge of pharmacology. The guide suggests that MAOIs should always be considered in cases of treatment-resistant depression (including those melancholic in nature), and prior to electroconvulsive therapy—while taking into account of patient preference. In selected cases, they may be considered earlier in the treatment algorithm than has previously been customary, and should not be regarded as drugs of last resort; they may prove decisively effective when many other treatments have failed. The guide clarifies key points on the concomitant use of incorrectly proscribed drugs such as methylphenidate and some tricyclic antidepressants. It also illustrates the straightforward “bridging” methods that may be used to transition simply and safely from other antidepressants to MAOIs.
South Africa has embarked on major health policy reform to deliver universal health coverage through the establishment of National Health Insurance (NHI). The aim is to improve access, remove financial barriers to care, and enhance care quality. Health technology assessment (HTA) is explicitly identified in the proposed NHI legislation and will have a prominent role in informing decisions about adoption and access to health interventions and technologies. The specific arrangements and approach to HTA in support of this legislation are yet to be determined. Although there is currently no formal national HTA institution in South Africa, there are several processes in both the public and private healthcare sectors that use elements of HTA to varying extents to inform access and resource allocation decisions. Institutions performing HTAs or related activities in South Africa include the National and Provincial Departments of Health, National Treasury, National Health Laboratory Service, Council for Medical Schemes, medical scheme administrators, managed care organizations, academic or research institutions, clinical societies and associations, pharmaceutical and devices companies, private consultancies, and private sector hospital groups. Existing fragmented HTA processes should coordinate and conform to a standardized, fit-for-purpose process and structure that can usefully inform priority setting under NHI and for other decision makers. This transformation will require comprehensive and inclusive planning with dedicated funding and regulation, and provision of strong oversight mechanisms and leadership.
The sub-kilometre scale distribution of snow depth on Arctic sea ice impacts atmosphere-ice fluxes of energy and mass, and is of importance for satellite estimates of sea-ice thickness from both radar and lidar altimeters. While information about the mean of this distribution is increasingly available from modelling and remote sensing, the full distribution cannot yet be resolved. We analyse 33 539 snow depth measurements from 499 transects taken at Soviet drifting stations between 1955 and 1991 and derive a simple statistical distribution for snow depth over multi-year ice as a function of only the mean snow depth. We then evaluate this snow depth distribution against snow depth transects that span first-year ice to multiyear ice from the MOSAiC, SHEBA and AMSR-Ice field campaigns. Because the distribution can be generated using only the mean snow depth, it can be used in the downscaling of several existing snow depth products for use in flux modelling and altimetry studies.
There is limited information on the volume of antibiotic prescribing that is influenza-associated, resulting from influenza infections and their complications (such as streptococcal pharyngitis and otitis media). Here, we estimated age/diagnosis-specific proportions of antibiotic prescriptions (fills) for the Kaiser Permanente Northern California population during 2010–2018 that were influenza-associated. The proportion of influenza-associated antibiotic prescribing among all antibiotic prescribing was higher in children aged 5–17 years compared to children aged under 5 years, ranging from 1.4% [95% CI (0.7–2.1)] in aged <1 year to 2.7% (1.9–3.4) in aged 15–17 years. For adults aged over 20 years, the proportion of influenza-associated antibiotic prescribing among all antibiotic prescribing was lower, ranging from 0.7% (0.5–1) for aged 25–29 years to 1.6% (1.2–1.9) for aged 60–64 years. Most of the influenza-associated antibiotic prescribing in children aged under 10 years was for ear infections, while for age groups over 25 years, 45–84% of influenza-associated antibiotic prescribing was for respiratory diagnoses without a bacterial indication. This suggests a modest benefit of increasing influenza vaccination coverage for reducing antibiotic prescribing, as well as the potential benefit of other measures to reduce unnecessary antibiotic prescribing for respiratory diagnoses with no bacterial indication in persons aged over 25 years, both of which may further contribute to the mitigation of antimicrobial resistance.
The electoral district is the fundamental unit of representation in single- and multi-member electoral systems, yet most research shows little interest in district effects on election outcomes, focusing instead on national and individual factors. This is problematic as parties and candidates often put a great deal of effort into district-based campaigns. How, then, can we best capture district effects on party support? We propose a new method using official election returns and geospatial techniques. The result is a measure of how much of a party's vote share is explained by district effects. Using data from the 2006–2019 Canadian federal elections, we find that, on average, 6 to 10 per cent of the variation in a party's vote in Canada is explained by district effects. While district effects on party support are trivial for some districts, in others they account for more than 80 per cent of the variance in party vote shares. The effect of districts on party support is composed, in part, of electoral context, province, socio-economic factors and district campaign intensity. Importantly, the size and sources of district effects on party support vary across parties, suggesting heterogeneity. The benefits of our approach are threefold: (1) it is cost-effective, (2) it can be easily replicated in any setting—past or present—where districts are relevant electoral units and where districting is nonpartisan, and (3) it is responsive to differences in district composition and parties’ campaign effort.
Along with an increase in opioid deaths, there has been a desire to increase the accessibility of naloxone. However, in the absence of respiratory depression, naloxone is unlikely to be beneficial and may be deleterious if it precipitates withdrawal in individuals with central nervous system (CNS) depression due to non-opioid etiologies.
Objective:
The aim of this study was to evaluate how effective prehospital providers were in administering naloxone.
Methods:
This is a retrospective study of naloxone administration in two large urban Emergency Medical Service (EMS) systems. The proportion of patients who had a respiratory rate of at least 12 breaths per minute at the time of naloxone administration by prehospital providers was determined.
Results:
During the two-year study period, 2,580 patients who received naloxone by prehospital providers were identified. The median (interquartile range) respiratory rate prior to naloxone administration was 12 (6-16) breaths per minute. Using an a priori respiratory rate of under 12 breaths per minute to define respiratory depression, only 1,232 (47.8%; 95% CI, 50.3%-54.2%) subjects who received naloxone by prehospital providers had respiratory depression.
Conclusion:
This study showed that EMS providers in Los Angeles County, California (USA) frequently administered naloxone to individuals without respiratory depression.
Despite its global importance and the recognition of dementia as an international public health priority, interventions to reduce stigma of dementia are a relatively new and emerging field. The purpose of this review was to synthesize the existing literature and identify key components of interventions to reduce stigma of dementia. We followed Arksey and O’Malley’s scoping review process to examine peer-reviewed literature of interventions to reduce dementia-related stigma. A stigma-reduction framework was used for classifying the interventions: education (dispel myths with facts), contact (interact with people with dementia), mixed (education and contact), and protest (challenge negative attitudes). From the initial 732 references, 21 studies were identified for inclusion. We found a variety of education, contact, and mixed interventions ranging from culturally tailored films to intergenerational choirs. Findings from our review can inform the development of interventions to support policies, programs, and practices to reduce stigma and improve the quality of life for people with dementia.