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The mobility of a weed species is a strong determinant of the optimal management strategy, including whether area-wide management will be beneficial. In this paper, we examine the mobility and dispersal distances of flaxleaf fleabane [Conyza bonariensis (L.) Cronquist; syn.: Erigeron bonariensis L.], widely regarded as a highly mobile weed. We sampled individual weeds from two regions and sampled the same sites in the following season to conduct parentage analysis and assess intergenerational dispersal distances. We find high values of FIS across populations consistent with mostly self-fertilization, but also relatively high genotypic diversity, suggesting that outcrossing does occur at low rates. We find evidence for long-distance dispersal (more than 350 km) and detect dispersal distances of up to 71 km and 36 km within each of the two regions using parentage analysis. We also find high spatial genetic structure within the Riverina region, with sites in 2021 genetically very similar to sites in 2020, indicating that local dispersal may be a more important driver of population genetics than long-distance dispersal, perhaps due to the high rates of seed production and self-fertilization. Glyphosate resistance was not spatially structured in C. bonariensis in these regions, highlighting the role of movement, and significant proportions of susceptible plants were found in both regions. The high levels of mobility, including over potentially long distances, indicate that the value of control and preventing weed seed set is likely to extend beyond the farm and offer “area-wide” benefit.
Female genital schistosomiasis (FGS) is a chronic disease manifestation of the waterborne parasitic infection Schistosoma haematobium that affects up to 56 million women and girls, predominantly in sub-Saharan Africa. Starting from early childhood, this stigmatizing gynaecological condition is caused by the presence of Schistosoma eggs and associated toxins within the genital tract. Schistosoma haematobium typically causes debilitating urogenital symptoms, mostly as a consequence of inflammation, which includes bleeding, discharge and lower abdominal pelvic pain. Chronic complications of FGS include adverse sexual and reproductive health and rights outcomes such as infertility, ectopic pregnancy and miscarriage. FGS is associated with prevalent human immunodeficiency virus and may increase the susceptibility of women to high-risk human papillomavirus infection. Across SSA, and even in clinics outside endemic areas, the lack of awareness and available resources among both healthcare professionals and the public means FGS is underreported, misdiagnosed and inadequately treated. Several studies have highlighted research needs and priorities in FGS, including better training, accessible and accurate diagnostic tools, and treatment guidelines. On 6 September, 2024, LifeArc, the Global Schistosomiasis Alliance and partners from the BILGENSA Research Network (Genital Bilharzia in Southern Africa) convened a consultative, collaborative and translational workshop: ‘Female Genital Schistosomiasis: Translational Challenges and Opportunities’. Its ambition was to identify practical solutions that could address these research needs and drive appropriate actions towards progress in tackling FGS. Here, we present the outcomes of that workshop – a series of discrete translational actions to better galvanize the community and research funders.
In 2010, USAID catalyzed the formation of One Health University Networks as part of a holistic response designed to promote the One Health approach for addressing complex health challenges. This globally connected One Health University network now includes the African One Health University Network (AFROHUN) and the Southeast Asia University Network (SEAOHUN) and has representation from over 120 universities in 17 countries across Africa and Southeast Asia. Over more than 15 years of USAID investment, these networks have trained more than 85,000 students, in-service professionals and faculty around the world in One Health principles and collaborative problem solving, grounded in One Health core competencies. These One Health practitioners have gone on to contribute to improved global health security in their communities and countries. The evolution and maturation of these networks is a testament to a strong vision and dedication to the task by leadership and donors. As the global academic community continues to refine and adapt training methodologies for ‘future ready’ individuals, resources and examples from One Health University Networks stand as a legacy to build upon.
Global food security challenges, driven by the need to feed an estimated 10 billion people by 2050, require sustainable agricultural practices which strengthen nutritional adequacy while minimising environmental impacts. Yet, decision-making to foster food systems which consider both human and planetary health is growing in complexity. This paper, presented at an International Atomic Energy Agency-supported symposium at the 14th European Nutrition Conference of the Federation of European Nutrition Societies, highlights the potential of stable isotope techniques in generating valuable evidence to help support the development of sustainable food systems. It focuses on three methods: the dual tracer stable isotope technique for measuring protein digestibility, the Fe isotope dilution technique for assessing Fe absorption, loss and balance and the deuterium oxide dose-to-mother technique for estimating breast milk intake. The dual tracer isotope method provides a minimally invasive assessment of protein quality from a diverse variety of crops and novel sources, supporting the transition towards environmentally conscious, protein-rich diets. The Fe isotope dilution technique can be used to address Fe requirements across different population groups and calculate Fe absorption from whole diets or after consuming crops designed to be nutritionally sufficient, thus guiding dietary guidelines and agricultural strategies. Finally, the deuterium oxide dose-to-mother technique provides precise data on breast milk intake, underscoring the role of breastfeeding in sustaining optimal infant nutrition and the conservation of resources. These methods have the ability to generate critical evidence to support policy development and food system innovations that prioritise human health and environmental preservation.
Mobile health (mHealth) platforms have the potential to increase access to evidence-based interventions in low-resource settings. This study applied a user-centered design (UCD) approach to develop and evaluate an mHealth supervision tool for community health workers (CHWs) delivering an early childhood development intervention in rural Sierra Leone. We engaged CHWs (N=8) and supervisors (N=4) in focus group discussions, user testing sessions and exit interviews to gather feedback on the mHealth supervision tool’s usability and acceptability. Mixed methods findings indicated that the tool was generally well-received and perceived as easy to use, but there were also challenges related to connectivity, phone charging and the need for more comprehensive training and support. Overall, this study suggests that a UCD approach can promote the usability of mHealth tools to support CHWs in delivering evidence-based interventions in low-resource settings, highlighting the importance of addressing contextual challenges and providing adequate training and support to ensure the effectiveness and sustainability of such tools.
This article examines the ways in which the Sino-Canadian relationship has shaped Canadian legal structures and vice versa. The Canadian state’s anxieties about Chinese foreign policy have led to the “securitization” of various domains of domestic law, whereby the state has emphasized the national security implications of legal concepts, decisions, and regimes. This securitization may fuel discrimination towards Chinese Canadians, and the article suggests reforms that the Canadian state can adopt as it seeks to simultaneously implement a robust China strategy and avoid the mistreatment of Chinese Canadians.
Dignity is perceived as being valued and respected. Maintaining dignity throughout illness is a fundamental principle of palliative care. Dignity can be influenced through family caregiver’s communication, support, and acts of empathy or indifference among other factors. The perception of dignity and the practices adopted by family caregivers to preserve the dignity of their ill relative with serious illness in Lebanon are explored in this paper.
Methods
This is a part of a larger study that explored the understanding of dignity from patients’ and family caregivers’ perspectives in a palliative care context. Data collection involved in-depth interviews with 15 family caregivers. Interviews were analyzed using reflective thematic analysis.
Results
Four main themes, that explained how family caregivers understand, and uphold their relative’s dignity during illness, were developed:
(a) Familial duty expressed through presence and compassion;
(b) Holistic care and financial stability;
(c) Social connection and family roles;
(d) Compassionate services and communication.
Family caregivers maintained the dignity of their ill relatives through being there, compassionate communication, supporting the personal and medical needs of the patient, and helping them preserve their family role. Family caregiving was often underpinned by religious values and a sense of duty. Compassionate services and effective communication were essential to preserve dignity of the ill relative during hospitalizations.
Significance of results
Family caregivers assume multiple roles in fostering the dignity of relatives with serious illnesses. It is crucial that family caregivers are supported by policies, healthcare systems, and community initiatives as patients cannot thrive nor sustain dignity without their support.
In great depth, Volume II examines the escalation of the Vietnam War and its development into a violent stalemate, beginning with the overthrow of the Ngô Đình Diệm in 1963 to the aftermath of the 1968 Tết Offensive. This five-year period was, for the most part, the fulcrum of a three-decades-long struggle to determine the future of Vietnam and was marked by rival spirals of escalation generated by the Democratic Republic of Vietnam and the United States. The volume explores the war's military aspects on all sides, the politics of war in the two Vietnams and the United States, and the war's international and transnational dimensions in politics, protest, diplomacy, and economics, while also paying close attention to the agency of historical actors on both sides of the conflict in South Vietnam.
An analytic technique for the study of trait variability is presented. An expression for the average variance from test to test and an expression for the variance of these variances are derived in terms of the number of tests and the intercorrelations between them, and limiting cases are examined. The question of the true relationship between the nature of the distribution of test scores in a sample of N persons and the nature of the distribution of n traits in a single individual is discussed, and other problems are introduced.
This publication presents the results of the excavation in 1960 of a group of Minoan tombs on the lower slopes of Ailias, on the east side of the River Kairatos, in an area almost opposite the Temple Tomb at Knossos. One or two of these tombs were built in Middle Minoan times. Tomb I was used again for four burials in Late Minoan II–IIIA, the period when the other three tombs (II–IV) appear to have been exclusively used. The publication presents the excavation's ceramic and other small finds and offers a detailed study of the skeletal remains. Of special interest are the following aspects: (1) the excavation's careful documentation – particularly by the standards of the time – with considerable attention paid to stratigraphy and the production of section drawings; (2) the tombs’ architecture; (3) the use of wooden coffins; (4) the lack – to a large extent – of finds in association with the bodies buried in these tombs; and (5) the funerary sequence in one of the few locations in the Knossos valley where both Neopalatial as well as Final Palatial use is attested. The proximity to and (re)use of Neopalatial tombs during the Late Minoan II–IIIA period and the need of some members of the local society to associate themselves with pre-existing burial structures are discussed. This publication contributes to ongoing discussions on bone and object manipulation, plus the numbers of burials per tomb, while revisiting the ‘richness’ levels of the Knossian tombs. It also places emphasis on taphonomy, the transition from Late Minoan I to II, and the funeral experience. It is argued that burying the dead in a purposefully formed space (i.e., in a rock-cut tomb) may have constituted an action of particular social and/or religious importance even in burials lacking any significant quantities and/or a diverse range of objects. The most important ramifications stemming from this study are assessed at the end of the paper.
In great depth, Volume II examines the escalation of the Vietnam War and its development into a violent stalemate, beginning with the overthrow of Ngô Đình Diệm in 1963 to the aftermath of the 1968 Tet Offensive. This five-year period was, for the most part, the fulcrum of a three-decade struggle to determine the future of Vietnam and was marked by rival spirals of escalation generated by the Democratic Republic of Vietnam and the United States. The volume explores the war’s military aspects on all sides, the politics of war in the two Vietnams and the United States, and the war’s international and transnational dimensions in politics, protest, diplomacy, and economics, while also paying close attention to the agency of historical actors on both sides of the conflict in South Vietnam.