Basal crevasses threaten the stability of ice shelves through the potential to form rifts and calve icebergs. Furthermore, it is important to determine the dependence of crevasse stability on temperature due to large vertical temperature variations on ice shelves. In this work, considering the vertical temperature profile through ice viscosity, we compare (1) the theoretical crack depths and (2) the threshold stress causing the transition from basal crevasses to full thickness fractures in several fracture theories. In the Zero Stress approximation, the depth-integrated force at the crevassed and non-crevassed location are unbalanced, violating the volume-integrated Stokes equation. By incorporating a Horizontal Force Balance (HFB) argument, recent work showed analytically that the threshold stress for rift initiation is only half of that predicted by the Zero Stress approximation. We generalize the HFB theory to show that while the temperature profile influences crack depths, the threshold rifting stress is insensitive to temperature. We compare with observations and find that HFB best matches observed rifts. Using HFB instead of Zero Stress for cracks in an ice-sheet model would substantially enlarge the predicted fracture depth, reduce the threshold rifting stress and potentially increase the projected rate of ice shelf mass loss.

In 2018, an Ionplus 200 kV MIni-CArbon DAting System (MICADAS) accelerator mass spectrometer (AMS) was installed at the Laboratory of AMS Dating and the Environment, Nanjing University (NJU-AMS Laboratory), China. The NJU-AMS Laboratory is largely devoted to research on radiocarbon dating and 14C analysis in fields of earth, environmental and archaeological sciences. The laboratory has successfully employed various pretreatment methods, including routine pretreatment of tree rings, buried wood and subfossil wood, seeds, charcoal, pollen concentrates, organic matter, and shells. In this study, operational status of the NJU-AMS is presented, and results of radiocarbon measurements made on different sample types are reported. Measurements on international standards, references of known age, and blank samples demonstrate that the NJU-AMS runs stably and has good reproducibility on measurement of single samples. The facility is capable of measuring 14C in samples with the precision and accuracy that meet the requirements for investigating annual 14C changes, history-prehistory age dating, and Late Quaternary stratigraphic chronology research.

The target backsheath field acceleration mechanism is one of the main mechanisms of laser-driven proton acceleration (LDPA) and strongly depends on the comprehensive performance of the ultrashort ultra-intense lasers used as the driving sources. The successful use of the SG-II Peta-watt (SG-II PW) laser facility for LDPA and its applications in radiographic diagnoses have been manifested by the good performance of the SG-II PW facility. Recently, the SG-II PW laser facility has undergone extensive maintenance and a comprehensive technical upgrade in terms of the seed source, laser contrast and terminal focus. LDPA experiments were performed using the maintained SG-II PW laser beam, and the highest cutoff energy of the proton beam was obviously increased. Accordingly, a double-film target structure was used, and the maximum cutoff energy of the proton beam was up to 70 MeV. These results demonstrate that the comprehensive performance of the SG-II PW laser facility was improved significantly.

Colliding collisionless shocks appear in a great variety of astrophysical phenomena and are thought to be possible sources of particle acceleration in the Universe. We have previously investigated particle acceleration induced by single super-critical shocks (whose magnetosonic Mach number is higher than the critical value of 2.7) (Yao et al., Nat. Phys., vol. 17, issue 10, 2021, pp. 1177–1182; Yao et al., Matter Radiat. Extrem., vol. 7, issue 1, 2022, 014402), as well as the collision of two sub-critical shocks (Fazzini et al., Astron. Astrophys., vol. 665, 2022, A87). Here, we propose to make measurements of accelerated particles from interpenetrating super-critical shocks to observe the ‘phase-locking effect’ (Fazzini et al., Astron. Astrophys., vol. 665, 2022, A87) from such an event. This effect is predicted to significantly boost the energy spectrum of the energized ions compared with a single super-critical collisionless shock. We thus anticipate that the results obtained in the proposed experiment could have a significant impact on our understanding of one type of primary source (acceleration of thermal ions as opposed to secondary acceleration mechanisms of already energetic ions) of ion energization of particles in the Universe.

Planting patterns have significant effects on rice growth. Nonetheless, little is known about differences in annual crop yield and resource utilization among mechanized rice planting patterns in a rice–wheat cropping system. Field experiments were conducted from 2014 to 2017 using three treatments: pot seedling transplanting for rice and row sowing for wheat (PST-RS), carpet seedling transplanting for rice and row sowing for wheat (CST-RS) and row sowing for both crops (RS-RS). The results showed that, compared with RS-RS, PST-RS and CST-RS prolonged annual crop growth duration by 25–26 and 13–15 days, increased effective accumulated temperature by 399 and 212°C days and increased cumulative solar radiation by 454 and 228 MJ/m2 because of the earlier sowing of rice by 28 and 16 days in PST-RS and CST-RS, respectively. Compared with RS-RS, the annual crop yield of PST-RS and CST-RS increased by 3.1–3.8 and 2.0–2.6 t/ha, respectively, because of the increase in the number of spikelets/kernels per hectare, aboveground biomass, mean leaf area index and grain–leaf ratio. In addition, temperature production efficiency, solar radiation production efficiency and solar radiation use efficiency were higher in PST-RS, followed by CST-RS and RS-RS. These results suggest that mechanized rice planting patterns such as PST-RS increase annual crop production in rice–wheat cropping systems by increasing yield and solar energy utilization.

We report the experimental results of the commissioning phase in the 10 PW laser beamline of the Shanghai Superintense Ultrafast Laser Facility (SULF). The peak power reaches 2.4 PW on target without the last amplifying during the experiment. The laser energy of 72 ± 9 J is directed to a focal spot of approximately 6 μm diameter (full width at half maximum) in 30 fs pulse duration, yielding a focused peak intensity around 2.0 × 1021 W/cm2. The first laser-proton acceleration experiment is performed using plain copper and plastic targets. High-energy proton beams with maximum cut-off energy up to 62.5 MeV are achieved using copper foils at the optimum target thickness of 4 μm via target normal sheath acceleration. For plastic targets of tens of nanometers thick, the proton cut-off energy is approximately 20 MeV, showing ring-like or filamented density distributions. These experimental results reflect the capabilities of the SULF-10 PW beamline, for example, both ultrahigh intensity and relatively good beam contrast. Further optimization for these key parameters is underway, where peak laser intensities of 1022–1023 W/cm2 are anticipated to support various experiments on extreme field physics.

Dry wind-tunnel (DWT) flutter test systems model the unsteady distributed aerodynamic force using various electromagnetic exciters. They can be used to test the aeroelastic and aeroservoelastic stability of smart aircraft or high-speed flight vehicles. A new parameterised modelling method at the full system level based on the generalised force equivalence for DWT flutter systems is proposed herein. The full system model includes the structural dynamic model, electromechanical coupling model and fast aerodynamic computation model. An optimisation search method is applied to determine the best locations for measurement and excitation by introducing Fisher’s information matrix. The feasibility and accuracy of the proposed system-level numerical DWT modelling method have been validated for a plate aeroelastic model with four exciters/transducers. The effects of key parameters including the number of exciters, the control time delay, the noise interference and the electrical parameters of the electromagnetic exciter model have also been investigated. The numerical and experimental results indicate that the proposed modelling method achieves good accuracy (with deviations of less than 1.5% from simulations and 4.5% from experimental test results for the flutter speed) and robust performance even in uncertain environments with a 10% noise level.

The aim of this study was to explore the frequency and distribution of gene mutations that are related to isoniazid (INH) and rifampin (RIF)-resistance in the strains of the multidrug-resistant tuberculosis (MDR-TB) Mycobacterium tuberculosis (M.tb) in Beijing, China. In this retrospective study, the genotypes of 173 MDR-TB strains were analysed by spoligotyping. The katG, inhA genes and the promoter region of inhA, in which genetic mutations confer INH resistance; and the rpoB gene, in which genetic mutations confer RIF resistance, were sequenced. The percentage of resistance-associated nucleotide alterations among the strains of different genotypes was also analysed. In total, 90.8% (157/173) of the MDR strains belonged to the Beijing genotype. Population characteristics were not significantly different among the strains of different genotypes. In total, 50.3% (87/173) strains had mutations at codon S315T of katG; 16.8% (29/173) of strains had mutations in the inhA promoter region; of them, 5.5% (15/173) had point mutations at −15 base (C→T) of the inhA promoter region. In total, 86.7% (150/173) strains had mutations at rpoB gene; of them, 40% (69/173) strains had mutations at codon S531L of rpoB. The frequency of mutations was not significantly higher in Beijing genotypic MDR strains than in non-Beijing genotypes. Beijing genotypic MDR-TB strains were spreading in Beijing and present a major challenge to TB control in this region. A high prevalence of katG Ser315Thr, inhA promoter region (−15C→T) and rpoB (S531L) mutations was observed. Molecular diagnostics based on gene mutations was a useful method for rapid detection of MDR-TB in Beijing, China.

Two new species of egg parasitoids, Oobius saimaensis Yao and Mottern new species and Oobius fleischeri Yao and Duan new species (Hymenoptera: Encyrtidae), are described from eggs of Agrilus fleischeri Obenberger, 1925 (Coleoptera: Buprestidae). Agrilus fleischeri is a phloem-feeding woodborer of poplar (Populus Linnaeus; Salicaceae) in northeastern China. These two species can be distinguished morphologically as O. fleischeri has five tarsomeres and O. saimaensis has four tarsomeres. Although O. saimaensis is morphologically similar to its sympatric congener O. agrili Zhang and Hang, 2005, an important natural enemy of the invasive emerald ash borer, Agrilus planipennis Fairmaire, 1888, molecular phylogenetics and morphological data indicate that they are distinct species. Phylogenetic relationships among the new species and other closely related species are also inferred by using DNA sequence data from several ribosomal and mitochondrial genes. In addition, we expand the known distribution of Oobius primorskyensis Yao and Duan, 2016 to include South Korea.

We present an effective reduced-order model (ROM) technique to couple an incompressible flow with a transversely vibrating bluff body in a state-space format. The ROM of the unsteady wake flow is based on the Navier–Stokes equations and is constructed by means of an eigensystem realization algorithm (ERA). We investigate the underlying mechanism of vortex-induced vibration (VIV) of a circular cylinder at low Reynolds number via linear stability analysis. To understand the frequency lock-in mechanism and self-sustained VIV phenomenon, a systematic analysis is performed by examining the eigenvalue trajectories of the ERA-based ROM for a range of reduced oscillation frequency $(F_{s})$ , while maintaining fixed values of the Reynolds number ( $Re$ ) and mass ratio ( $m^{\ast }$ ). The effects of the Reynolds number $Re$ , the mass ratio $m^{\ast }$ and the rounding of a square cylinder are examined to generalize the proposed ERA-based ROM for the VIV lock-in analysis. The considered cylinder configurations are a basic square with sharp corners, a circle and three intermediate rounded squares, which are created by varying a single rounding parameter. The results show that the two frequency lock-in regimes, the so-called resonance and flutter, only exist when certain conditions are satisfied, and the regimes have a strong dependence on the shape of the bluff body, the Reynolds number and the mass ratio. In addition, the frequency lock-in during VIV of a square cylinder is found to be dominated by the resonance regime, without any coupled-mode flutter at low Reynolds number. To further discern the influence of geometry on the VIV lock-in mechanism, we consider the smooth curve geometry of an ellipse and two sharp corner geometries of forward triangle and diamond-shaped bluff bodies. While the ellipse and diamond geometries exhibit the flutter and mixed resonance–flutter regimes, the forward triangle undergoes only the flutter-induced lock-in for $30\leqslant Re\leqslant 100$ at $m^{\ast }=10$ . In the case of the forward triangle configuration, the ERA-based ROM accurately predicts the low-frequency galloping instability. We observe a kink in the amplitude response associated with 1:3 synchronization, whereby the forward triangular body oscillates at a single dominant frequency but the lift force has a frequency component at three times the body oscillation frequency. Finally, we present a stability phase diagram to summarize the VIV lock-in regimes of the five smooth-curve- and sharp-corner-based bluff bodies. These findings attempt to generalize our understanding of the VIV lock-in mechanism for bluff bodies at low Reynolds number. The proposed ERA-based ROM is found to be accurate, efficient and easy to use for the linear stability analysis of VIV, and it can have a profound impact on the development of control strategies for nonlinear vortex shedding and VIV.

We present an active feedback blowing and suction (AFBS) procedure via model reduction for unsteady wake flow and the vortex-induced vibration (VIV) of circular cylinders. The reduced-order model (ROM) for the AFBS procedure is developed by the eigensystem realization algorithm (ERA), which provides a low-order representation of the unsteady flow dynamics in the neighbourhood of the equilibrium steady state. The actuation is considered via vertical suction and a blowing jet at the porous surface of a circular cylinder with a body-mounted force sensor. While the optimal gain is obtained using a linear quadratic regulator (LQR), Kalman filtering is employed to estimate the approximate state vector. The feedback control system shifts the unstable eigenvalues of the wake flow and the VIV system to the left half-complex-plane, and subsequently results in suppression of the vortex street and the VIV in elastically mounted structures. The resulting controller designed by a linear low-order approximation is able to suppress the nonlinear saturated state of wake vortex shedding from the circular cylinder. A systematic linear ROM-based stability analysis is performed to understand the eigenvalue distribution for the flow past stationary and elastically mounted circular cylinders. The results from the ROM analysis are consistent with those obtained from full nonlinear fluid–structure interaction simulations, thereby confirming the validity of the proposed ROM-based AFBS procedure. A sensitivity study on the number of suction/blowing actuators, the angular arrangement of actuators and the combined versus independent control architectures has been performed for the flow past a stationary circular cylinder. Overall, the proposed control concept based on the ERA-based ROM and the LQR algorithm is found to be effective in suppressing the vortex street and the VIV for a range of reduced velocities and mass ratios.

This cross-sectional study aimed to examine and compare prevalence and correlates of whole blood Epstein–Barr virus (EBV) DNA between HIV-positive and HIV-negative men who have sex with men (MSM). Five hundred and four HIV-positive MSM and 504 age-matched HIV-negative MSM were recruited from an HIV counseling and testing clinic in Shanghai, China from November 2014 to November 2015 and were administered with a face-to-face questionnaire interview. Whole blood EBV DNA was tested by nested polymerase chain reaction assays on EBNA-1, EBNA-2, and LMP-1 genes. The prevalence of whole blood EBV DNA was 56·0% (95% CI 51·7–60·3%) among HIV-positive MSM and 26·0% (95% CI 22·4–30·0%) among HIV-negative MSM. Whole blood EBV DNA positivity was significantly associated with HIV infection (adjusted odds ratio (aOR) 3·43, 95% CI 2·58–4·57) and frequent intake of pickled, smoked, or salty food (aOR 1·71, 95% CI 1·02–2·86) in the whole sample, and with <200 cells/μl CD4 cell counts (aOR 1·79, 95% CI 1·05–3·05) and pickled, smoked, or salty food intake (aOR 3·14, 95% CI 1·39–7·08) in HIV-positive group. HIV-infected MSM are at higher risk of active EBV replication than HIV-uninfected MSM, underscoring needs of surveillance and research on EBV-related carcinogenesis in this population.

Knowledge about vegetation dynamics during the last glacial and deglacial periods in southeastern North America is under-constrained owing to low site density and problematic chronologies. New pollen records from two classic sites, Anderson Pond, TN, and Jackson Pond, KY, supported by AMS 14C age models, span 25.2–13.7 ka and 31.0–15.4 ka, respectively. A transition from Pinus dominance to Picea dominance is recorded at Jackson Pond ca. 26.2 ka, ~ coincident with Heinrich Event H2. Anderson and Jackson Ponds record a transition from conifer to deciduous-tree dominance ~ 15.9 and 15.4 ka, respectively, marking the development of no-analog vegetation characterized by moderate to high abundances of Picea, Quercus, Carya, Ulmus, Fraxinus, Ostrya/Carpinus, Cyperaceae, and Poaceae, and preceding by ~ 2000 yr the advent of similar no-analog vegetation in glaciated terrain to the north. No-analog vegetation developed as a time-transgressive, south-to-north pattern, mediated by climatic warming. Sporormiella abundances are consistently low throughout the Jackson and Anderson Pond records, suggesting that megafaunal abundances and effects on vegetation varied regionally or possibly that the Sporormiella signal was not well-expressed at these sites. Additional records with well-constrained chronologies are necessary to assess patterns and mechanisms of vegetation dynamics during the last glacial and deglacial periods.

Functionally graded material (FGM) has some particular characteristics due to the gradual variation of physical properties. The study on mechanical behavior of FGM is of great research value. In this work, a large scale FGM which filled with small glass spheres has been prepared by gravity assisted casting technique. The elastic material constants in static condition are measured. One optical experimental method, coherent gradient sensing (CGS), is introduced to study the mechanical behavior of FGM which has variation of material property in power-law. The governing equations of CGS which is used to represent the optics-mechanics relation of the singular field near the point of the outside force are derived based on the power-law asymptotic expansion. The experimental result shows this CGS method as a nondestructive methodology can be used to detect the damage in FGM with high accuracy.

Studies of schizophrenia at drug-naive state and on antipsychotic medication have reported a number of regions of gray-matter (GM) abnormalities but the reports have been inconsistent. The aim of this study was to conduct multimodal meta-analysis to compare the cross-sectional voxel-based morphometry studies of brain GM in antipsychotic-naive first-episode schizophrenia (AN-FES) and those with antipsychotic treatment within 1 year (AT-FES) to determine the similarities and differences in these groups. We conducted two separate meta-analyses containing 24 studies with a sample size of 801 patients and 957 healthy controls. A multimodal meta-analysis method was used to compare the findings between AN-FES and AT-FES. Meta-regression analyses were done to determine the influence of different variables including age, duration of illness, and positive and negative symptom scores. Finally, jack-knife analyses were done to test the robustness of the results. AN-FES and AT-FES showed common patterns of GM abnormalities in frontal (gyrus rectus), superior temporal, left hippocampal and insular cortex. GM in the left supramarginal gyrus and left middle temporal gyrus were found to be increased in AN-FES but decreased in AT-FES, whereas left median cingulate/paracingulate gyri and right hippocampus GM was decreased in AN-FES but increased in AT-FES. Findings suggest that both AN-FES and AT-FES share frontal, temporal and insular regions as common anatomical regions to be affected indicating these to be the primary regions of GM abnormalities in both groups.