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Although some organizations encourage employees to generate radical ideas by implementing stretch goals, the relationship between stretch goals and radical creativity is complicated. Unfortunately, existing research has not adequately addressed this issue. Therefore, we integrate signaling theory with creativity-related research and propose that the interaction between stretch goals and cognitive flexibility predicts employees' willingness to take risks, thereby influencing their engagement in radical creative activities and ultimately affecting their radical creativity. To test our hypotheses, we conduct two empirical studies. The results suggest that, for employees with high cognitive flexibility, stretch goals increase their willingness to assume risks, thus leading to improved engagement in radical creative activities and enhancing their radical creativity. Conversely, for employees with low cognitive flexibility, stretch goals decrease their willingness to take risks, which hampers their engagement in radical creative activities and their radical creativity. The theoretical contributions and practical implications of this study are also discussed.
COVID-19 carriers experience psychological stresses and mental health issues such as varying degrees of stigma. The Social Impact Scale (SIS) can be used to measure the stigmatisation of COVID-19 carriers who experience such problems.
Aims
To evaluate the reliability and validity of the Chinese version of the SIS, and the association between stigma and depression among asymptomatic COVID-19 carriers in Shanghai, China.
Method
A total of 1283 asymptomatic COVID-19 carriers from Shanghai Ruijin Jiahe Fangcang Shelter Hospital were recruited, with a mean age of 39.64 ± 11.14 years (59.6% male). Participants completed questionnaires, including baseline information and psychological measurements, the SIS and Self-Rating Depression Scale. The psychometrics of the SIS and its association with depression were examined through exploratory factor analysis, confirmatory factor analysis and receiver operating characteristic analysis.
Results
The average participant SIS score was 42.66 ± 14.61 (range: 24–96) years. Analyses suggested the model had four factors: social rejection, financial insecurity, internalised shame and social isolation. The model fit statistics of the four-factor SIS were 0.913 for the comparative fit index, 0.902 for the Tucker–Lewis index and 0.088 for root-mean-square error of approximation. Standard estimated factor loadings ranged from 0.509 to 0.836. After controlling for demographic characteristics, the total score of the 23-item SIS predicted depression (odds ratio: 1.087, 95% CI 1.061–1.115; area under the curve: 0.84, 95% CI 0.788–0.892).
Conclusions
The Chinese version of the SIS showed good psychometric properties and can be used to assess the level of perceived stigma experienced by asymptomatic COVID-19 carriers.
Typical ophiolitic rock assemblages such as siliciclastic rocks, basalts and gabbros, together with the subduction-related intermediate-acidic intrusive rocks, are newly discovered in the Tongjiang-Fuyuan area of the Heilongjiang Provence, NE China. To determine the formation age and genesis of the mafic rocks (basalts and gabbros) and intermediate-acidic intrusive rocks (granodiorites) in the area, as well as their geodynamic settings, the whole-rock geochemical analysis and zircon LA-ICP-MS U-Pb dating were carried out. Zircon U-Pb results suggest that the granodiorites are 93–95 Ma and gabbro is 95 Ma, respectively. Geochemical results show that the gabbros and basalts exhibit characteristics of ocean island basalt (OIB) affinity and are typically related to having originated from mantle plumes. While the granodiorites show the nature of the island-arc magmatic rocks and may originate from the lower crust. Based on the coeval igneous rock associations and regional tectonic evolution, we conclude that the late Cretaceous magmatic rocks in the Tongjiang-Fuyuan area are the product of continuous subduction of the Palaeo-Pacific plate and reflect the subduction rollback process of the Palaeo-Pacific plate.
Burn patients are at high risk of central line–associated bloodstream infection (CLABSI). However, the diagnosis of such infections is complex, resource-intensive, and often delayed. This study aimed to investigate the epidemiology of CLABSI and develop a prediction model for the infection in burn patients. The study analysed the infection profiles, clinical epidemiology, and central venous catheter (CVC) management of patients in a large burn centre in China from January 2018 to December 2021. In total, 222 burn patients with a cumulative 630 CVCs and 5,431 line-days were included. The CLABSI rate was 23.02 CVCs per 1000 line-days. The three most common bacterial species were Acinetobacter baumannii, Staphylococcus aureus, and Pseudomonas aeruginosa; 76.09% of isolates were multidrug resistant. Compared with a non-CLABSI cohort, CLABSI patients were significantly older, with more severe burns, more CVC insertion times, and longer total line-days, as well as higher mortality. Regression analysis found longer line-days, more catheterisation times, and higher burn wounds index to be independent risk factors for CLABSI. A novel nomogram based on three risk factors was constructed with an area under the receiver operating characteristic curve (AUROC) value of 0.84 (95% CI: 0.782–0.898) with a mean absolute error of calibration curve of 0.023. The nomogram showed excellent predictive ability and clinical applicability, and provided a simple, practical, and quantitative strategy to predict CLABSI in burn patients.
Coastal eutrophication and hypoxia remain a persistent environmental crisis despite the great efforts to reduce nutrient loading and mitigate associated environmental damages. Symptoms of this crisis have appeared to spread rapidly, reaching developing countries in Asia with emergences in Southern America and Africa. The pace of changes and the underlying drivers remain not so clear. To address the gap, we review the up-to-date status and mechanisms of eutrophication and hypoxia in global coastal oceans, upon which we examine the trajectories of changes over the 40 years or longer in six model coastal systems with varying socio-economic development statuses and different levels and histories of eutrophication. Although these coastal systems share common features of eutrophication, site-specific characteristics are also substantial, depending on the regional environmental setting and level of social-economic development along with policy implementation and management. Nevertheless, ecosystem recovery generally needs greater reduction in pressures compared to that initiated degradation and becomes less feasible to achieve past norms with a longer time anthropogenic pressures on the ecosystems. While the qualitative causality between drivers and consequences is well established, quantitative attribution of these drivers to eutrophication and hypoxia remains difficult especially when we consider the social economic drivers because the changes in coastal ecosystems are subject to multiple influences and the cause–effect relationship is often non-linear. Such relationships are further complicated by climate changes that have been accelerating over the past few decades. The knowledge gaps that limit our quantitative and mechanistic understanding of the human-coastal ocean nexus are identified, which is essential for science-based policy making. Recognizing lessons from past management practices, we advocate for a better, more efficient indexing system of coastal eutrophication and an advanced regional earth system modeling framework with optimal modules of human dimensions to facilitate the development and evaluation of effective policy and restoration actions.
This paper presents a new method to reveal the relation between the surface deformation and near-field amplitude of a reflector antenna based on complex geometrical optics, which could be used as an efficient way to estimate the antenna surface verified by simulation results. The measurement process based on this method is envisaged to be realized by a single scanning of the near-field amplitude which would overcome many limitations of radio holography and phase retrieval methods such as the frequency and elevation. The largest source of error in the original deformation-amplitude equation (DAE) has been corrected by considering the Gaussian feed as a complex point source. To track the ray trajectory so that the improved DAE could be solved, an iteration method including a golden section search algorithm is designed to make the solution converge. By solving the modified DAE, simulation result shows that a more accurate solution could be obtained, and the antenna surface could be recovered to a root mean square error of under 30 microns.
This work reports experimental observation and theoretical explanation of the dynamics and morphology of a droplet passing through a soap film. During the process, the film undergoes four sequential responses: (1) film deformation upon droplet impact; (2) drop–film detachment; (3) coalescence of the film shell with the drop; (4) peel-off of the film shell. Physical models and the corresponding analytical expressions are developed to reveal the underlying physics for the observed four responses. It is identified that the film is an elongated catenoid under continuous stretch by the droplet, and that they separate at the fixed height of 5.8 times of the droplet radius while the detach point is located at the centre of the height. After separation, the droplet is wrapped with a film shell, which is then punctured by the ring tip of the converging surface wave at the impacting Weber number range of [45, 225]. The film shell then coalesces with the droplet, falls off with a fixed velocity and is eventually ejected as a bubble leaving the droplet with a transplanted surface of the soap solution.
The single initial Global Positioning System (GPS) has been expanded into multiple global and regional navigation satellite systems (multi-GNSS/RNSS) as the Global Navigation Satellite System (GLONASS) is restored and the BeiDou Navigation Satellite System (BDS), Galileo Satellite Navigation System (Galileo) and Quasi-Zenith Satellite System (QZSS) evolve. Using the differences among these five systems, the paper constructs a consolidated multi-GNSS/RNSS precise point positioning (PPP) observation model. A large number of datasets from Multi-GNSS Experiment (MGEX) stations are employed to evaluate the PPP performance of multi-GNSS/RNSS. The paper draws three main conclusions based on the experimental results. (1) The combined GPS/GLONASS/Galileo/BDS/QZSS presents the PPP with the shortest mean convergence time of 11·5 min, followed by that of GPS/GLONASS/Galileo/BDS (12·4 min). (2) The combined GPS/GLONASS/BDS/Galileo/QZSS shows the optimal PPP performance when the cut-off elevation angle is basically the same because of the rich observation data due to a large number of satellites. To be specific, for combined GPS/GLONASS/BDS/Galileo/QZSS, the PPP convergence percentage is 80·9% higher relative to other combined systems under 35° cut-off elevation angle, and the percentages of the root mean square values of PPP within 0–5 cm are enhanced by 80·5%, 81·5% and 87·3% in the North, East and Up directions relative to GPS alone at 35° cut-off elevation angle. (3) GPS alone fails to conduct continuous positioning due to the insufficiency of visible satellites at 40° cut-off elevation angle, while the kinematic PPP of multi-GNSS/RNSS remains capable of obtaining positioning solutions with relatively high accuracy, especially in the horizontal direction.
Sn–Sb alloy is an ideal candidate for lead-free solder; however, its performance has been inferior to that of Sn–Pb alloy. Here, the authors used ab initio molecular dynamics simulation to investigate the interatomic interaction in Sn–Sb-based lead-free solders. By calculating the electron density distribution, bond population, and partial density of states, the authors found that the Sn–Sb bonds are a mixture of nonlocalized metal and localized covalent bonds. The covalent bond between Sn and Sb is easy to break at higher temperatures, so Sn–Sb (6.4 wt%) had better fluidity than other studied Sn–Sb alloys. Furthermore, adding Cu or Ag into Sn–Sb alloys can decrease the strength of covalent bonds and stabilize the metal bonds, which improves the metallicity and wettability of the Sn–Sb–Cu and Sn–Sb–Cu–Ag systems when the temperature increases. These results are all in good agreement with experimental findings and have significant value for the development of new solder alloys.
To assess helical tomotherapy (TOMO) current clinical application and practice in mainland China.
Materials and methods:
Data were collected for all TOMO units clinically operational in mainland China by 30 April 2016, including (a) the distribution of installation and staffing levels; (b) types of cancers treated; (c) utilisation efficiency; (d) quality assurance; (e) maintenance; (f) optional features; and (g) satisfaction levels. The data were collected as a census and analysed qualitatively and quantitatively.
Results:
As of 30 April 2016, 23 TOMO units were used clinically by 22 hospitals in mainland China. In the same period, 22,558 cancer patients were treated. For TOMO units with more than a year of clinical utilisation, a median of 378 cases were treated annually per machine. The median daily operation was 10·5 hours, and treatment headcount was 38·3 patients. The median service outage rate was 2·6%, and the most common cause was malfunction of the multi-leaf collimator. In terms of overall satisfaction levels, 3 hospitals were very satisfied, 16 were satisfied and 3 considered their satisfaction level as average.
Findings:
The overall operation of TOMO is good, but there are some problems due to running at full capacity, lack of clinical efficacy research and insufficient quality assurance regulations.
We investigated the ecology and paleoecology of testate amoebae in peatlands of the Colombian páramo to assess the use of testate amoebae as paleoenvironmental indicators. Objectives were to (1) identify environmental controls on testate amoebae, (2) develop transfer functions for paleoenvironmental inference, and (3) examine testate amoebae in a Holocene peat core and compare our findings with other proxy records. Results from 96 modern samples indicate that testate amoebae are sensitive to pH and surface moisture, and cross-validation of transfer functions indicates potential for paleoenvironmental applications. Testate amoebae from the Triunfo Peatland in the Central Cordillera provided a proxy record of pH and water-table depth for the late Holocene, and inferred changes were correlated with peat C/N measurements during most of the record. Comparison with a lake-level reconstruction suggests that at least the major testate amoeba–inferred changes were driven by climate. Our work indicates that testate amoebae are useful paleoenvironmental indicators in high-elevation tropical peatlands.
Here we report a new find of abundant woody debris and cones in stratum of two sections located to the east of the Qinghai Lake basin in China. Analysis of the anatomical structure of the wood and cones confirmed that they are Picea crassifolia Kom. The results of accelerator mass spectrometry 14C dating indicate that the buried Qinghai spruce grew during 9.7–4.2 ka, and the ages of the large trunks or branches are mainly concentrated within the interval 7.5–6.5 ka. This finding gives direct evidence at the species level about the presence of coniferous forest in the early–middle Holocene in Qinghai lake basin. In addition, the buried cones suggest that the early-middle Holocene environment was suitable for the propagation of Picea crassifolia Kom. The variations in the occurrence of Qinghai spruce forest in the Holocene probably reflect changes in humidity/moisture. The humid early-middle Holocene was suitable for the growth and reproduction of Qinghai spruce forest, while a shift toward an increasingly arid climate during the late Holocene resulted in the disappearance of Picea crassifolia Kom. from the Qinghai Lake basin, although human activities may also have contributed to the environmental change.
Haemorrhagic fever with renal syndrome (HFRS) is transmitted to humans mainly by rodents and this transmission could be easily influenced by meteorological factors. Given the long-term changes in climate associated with global climate change, it is important to better identify the effects of meteorological factors of HFRS in epidemic areas. Shandong province is one of the most seriously suffered provinces of HFRS in China. Daily HFRS data and meteorological data from 2007 to 2012 in Shandong province were applied. Quasi-Poisson regression with the distributed lag non-linear model was used to estimate the influences of mean temperature and Diurnal temperature range (DTR) on HFRS by sex, adjusting for the effects of relative humidity, precipitation, day-of-the-week, long-term trends and seasonality. A total of 6707 HFRS cases were reported in our study. The two peaks of HFRS were from March to June and from October to December, particularly, the latter peak in 2012. The estimated effects of mean temperature and DTR on HFRS were non-linear. The immediate and strong effect of low temperature and high DTR on HFRS was found. The lowest temperature −8.86°C at lag 0 days indicated the largest related relative risk (RRs) with the reference (14.85 °C), respectively, 1.46 (95% CI 1.11–1.90) for total cases, 1.33 (95% CI 1.00–1.78) for the males and 1.76 (95% CI 1.12–2.79) for the females. Highest DTR was associated with a higher risk on HFRS, the largest RRs (95% CI) were obtained when DTR = 15.97 °C with a reference at 8.62 °C, with 1.26 (0.96–1.64) for total cases and 1.52 (0.97–2.38) for the female at lag 0 days, 1.22 (1.05–1.41) for the male at lag 5 days. Non-linear lag effects of mean temperature and DTR on HFRS were identified and there were slight differences for different sexes.
The aim of this study was to explore perinatal and early postnatal outcomes in fetuses with prenatally diagnosed d-transposition of the great arteries and impacts of standardised prenatal consultation.
Methods
All fetuses with prenatally diagnosed d-transposition of the great arteries prospectively enrolled at South China cardiac centre from 2011 to 2015. Standardised prenatal consultation was introduced in 2013 and comprehensive measures were implemented, such as establishing fetal CHD Outpatient Consultation Service, performing standard prenatal consultation according to specifications, and establishing a multidisciplinary team with senior specialists performing in-person consultations. Continuous follow-up investigation was conducted. Perinatal and postnatal outcomes were compared before and after consultation including live birth, elective termination of pregnancy, spontaneous fetal death, stillbirths, referral for surgery, and survival.
Results
In all, 146 fetuses were enrolled with 41 (28%) lost to follow-up. Among 105 remaining fetuses, 29 (28%) were live births and 76 (72%) were terminated. After consultation, live birth rate was higher (50 versus 33%) and termination rate was lower (50 versus 76%), although there was no statistical significance. Excluding three live births without postnatal d-transposition of the great arteries, 65% (17/26) underwent arterial switch operation within 30 days. A total of three in-hospital deaths occurred and during the 10-month follow-up period, one death was observed. In one case, the switch procedure was performed at 13 months and the infant survived. Out of eight infants without arterial switch operation, two died.
Conclusions
Live birth rate increased after consultation; however, termination remained high. Combining termination, patients without arterial switch operation, and operative mortality, outcomes of d-transposition of the great arteries infants can be improved. Standard consultation, multidisciplinary collaboration, and improved perinatal care are important to improve outcomes.
Sign truncated matching pursuit (STrMP) algorithm is presented in this paper. STrMP is a new greedy algorithm for the recovery of sparse signals from the sign measurement, which combines the principle of consistent reconstruction with orthogonal matching pursuit (OMP). The main part of STrMP is as concise as OMP and hence STrMP is simple to implement. In contrast to previous greedy algorithms for one-bit compressed sensing, STrMP only need to solve a convex and unconstrained subproblem at each iteration. Numerical experiments show that STrMP is fast and accurate for one-bit compressed sensing compared with other algorithms.
A large schizophrenia genome-wide association study (GWAS) and a subsequent extensive replication study of individuals of European ancestry identified eight new loci with genome-wide significance and suggested that the MIR137-mediated pathway plays a role in the predisposition for schizophrenia.
Aims
To validate the above findings in a Han Chinese population.
Method
We analysed the single nucleotide polymorphisms (SNPs) in the newly identified schizophrenia candidate loci and predictedMIR137 target genes based on our published Han Chinese populations (BIOX) GWAS data. We then analysed 18 SNPs from the candidate regions in an independent cohort that consisted of 3585 patients with schizophrenia and 5496 controls of Han Chinese ancestry.
Results
We replicated the associations of five markers (P<0.05), including three that were located in the predicted MIR137 target genes. Two loci(ITIH3/4: rs2239547, P=1.17×10–10 and CALN1: rs2944829,P=9.97×10–9) exhibited genome-wide significance in the Han Chinese population.
Conclusions
The ITIH3/4 locus has been reported to be of genome-wide significance in the European population. The successful replication of this finding in a different ethnic group provides stronger evidence for the association between schizophrenia and ITIH3/4. We detected the first genome-wide significant association of schizophrenia with CALN1, which is a predicted target ofMIR137, and thus provide new evidence for the associations between MIR137 targets and schizophrenia.
In this work, we investigated the influence of N-polar wet etching on the properties of nitride-based hexagonal pyramids array (HPA) vertical-injection light emitting diodes (V-LEDs). The cathodeluminescence images showed the randomly distribution of hexagonal pyramids with isolated active regions. The transmission electron microscopy images demonstrated the reduced density of threading dislocations. The IQE was estimated by temperature dependence of photoluminescence, which showed 30% increase for HPA V-LEDs compared with broad area (BA) V-LEDs. The improved extraction efficiency was verified by finite difference time domain simulation, which was 20% higher than that of roughened BA V-LEDs. The electrical properties of HPA V-LEDs were measured by conductive atomic force microscopy (CAFM) measurements. HPA V-LEDs exhibited much lower leakage current due to the improved crystal quality.
The mechanism leading to RT ferromagnetism in Gd-doped GaN is not agreed upon, despite many experimental and theoretical reports. Oxygen impurities have been proposed as a possible contributor to ferromagnetic behavior in GaN:Gd films. In this report, GaN:Gd thin films grown by MOCVD using two different metalorganic Gd precursors are examined. The two precursors are (TMHD)3Gd, which contains oxygen, and Cp3Gd, which does not. The films have been characterized by XRD, VSM, and EDS. EDS measurements indicate that the TMHD3Gd samples contain oxygen, while the Cp3Gd samples do not, and VSM scans show that the TMHD3Gd samples exhibit much higher magnetic moments than the Cp3Gd samples, supporting the theory that oxygen enhances the ferromagnetic behavior of GaN:Gd.