Shift work-induced circadian disruption has been linked to various cardiometabolic diseases, including obesity, diabetes and CVD. Limited studies have explored the impact of different variables such as night work durations, intensities and chronotype on cardiometabolic risk. This study aimed to determine the impact of circadian disruption on cardiometabolic risk markers in shift workers. This case–control study was conducted with 104 male workers (shift workers; n 52, mean age; 43·3 (sd 10·2), and non-shift workers; n 52, mean age; 41·2 (sd 9·8)). Shift work details were determined via an interviewer-administered questionnaire. Cardiometabolic risk was evaluated through anthropometric (height, weight, waist circumference and body composition), biochemical (fasting glucose and lipid profile), clinical (blood pressure) and dietary assessment (24-h recalls from working and non-working days). The chronotype was determined via the Munich Chronotype Questionnaire (MCTQ). Shift workers had significantly higher mean body fat percentage (31·7, 22·7 % P = 0·031), systolic blood pressure (SBP) (138·6, 128·5 mmHg P = 0·009), pulse rate (78·7, 72·3 bpm P = 0·015), TAG (1·60, 1·30 mmol/l P = 0·021) and LDL-cholesterol (3·90, 3·40 mmol/l P = 0·012) than non-shift workers. Evening chronotype shift workers had significantly higher visceral fat levels (12·8, 8·90 P = 0·001), SBP (137·0, 127·6 mmHg P = 0·006), pulse rate (82·7, 73·3 bpm P = 0·005) and LDL-cholesterol (4·00, 3·40 mmol/l P = 0·039) than shift workers with a morning chronotype. In conclusion, shift workers exhibited higher metabolic risk markers than non-shift workers. Shift workers with evening chronotypes had higher cardiometabolic risk than morning chronotypes. Further research is warranted to elucidate the underlying mechanisms and inform targeted interventions for individuals engaged in shift work, considering chronotypes.

There is increased interest in self-selected exclusionary diet patterns, specifically vegetarian, vegan, and gluten-free (GF) diets, but there is a lack of research exploring the beliefs and behaviours surrounding these diets in Canadians capable of bearing children (CCBC). The goal of this study was to explore the beliefs and behaviours of CCBC who follow vegetarian, vegan, and/or GF diets using mixed methods. A self-administered online Qualtrics™ survey containing 102 questions was conducted using open text and closed format questions. Continuous variables were summarized using mean and standard deviation while percentages were used to summarize categorical variables. Qualitative data was analysed using thematic analysis. A total of 271 CCBC between 18–45 years of age were analysed, with 27%, 22%, and 3.7% indicating they followed a vegan, vegetarian, and/or GF diet, respectively. Three main themes emerged that influenced CCBC beliefs about their chosen diet. The belief that these diets are healthy or could impart health in some way, was the main reason for following their chosen diet, especially in those who identified as vegetarian. Ethical/moral concerns, primarily around animal welfare and the environment, was the second theme for following their chosen dietary pattern, especially amongst those who identified as vegan. Perception of social judgement in the forms of criticism, guilt, and isolation were noted by some CCBC, with family, friends, and colleagues interacting differently with them because of their dietary choices. These findings serve to enhance our understanding of the beliefs and behaviours of CCBC who choose to follow exclusionary diets.

While increasing seafood consumption may help address micronutrient deficiencies and metabolic disorders, evidence supporting this recommendation in the Indian context remains limited and inconclusive. Using the nationally representative cross-sectional 2019–2021 National Family Health Survey dataset, we investigated the association of fish consumption frequency with anaemia and metabolic disorders (overweight/obesity, hypertension and hyperglycaemia) among adult men (aged 15–54 years) and women (aged 15–49 years) in India. A control function (CF) method was employed to examine the association in individuals who consumed fish daily and those who reported consuming fish daily/weekly. The analysis was restricted to non-vegetarians (who reported ever consuming egg, fish or meat). Overall, 86·9 % of men and 74·7 % of women were non-vegetarians. CF analysis revealed that both daily and daily/weekly fish consumption were associated with a reduced risk of anaemia among both men and women. Daily fish consumers exhibited increased likelihood of overweight/obesity (men: β: 0·405, 95 % CI: 0·074, 0·735, P: 0·017; women: β: 0·248, 95 % CI 0·125, 0·370, P < 0·001). Conversely, daily/weekly fish intake was associated with a reduced risk of overweight/obesity in men (β: −0·041, 95 % CI: −0·069, −0·013; P: 0·004). Daily/weekly fish consumption was associated with a reduced risk of hypertension and increased odds of hyperglycaemia among men. Fish consumption demonstrated a potentially protective relationship against hypertension in women, regardless of how often they consumed fish, while also being associated with a higher prevalence of hyperglycaemia. Indian adults can improve their health by eating more fish, which can help fight anaemia and may also reduce overweight/obesity and high blood pressure.

Although studies had suggested that monosodium glutamate (MSG) may serve as a salt substitute in processed foods, its market impact remains unclear. This study was aimed to: (1) identify MSG in ingredient lists, (2) compare sodium levels in products with and without MSG, (3) examine the association between MSG and other umami enhancers, and (4) assess manufacturers’ adherence to the Food Regulation 1985 for MSG declaration. An observational cross-sectional market survey was conducted during the Movement Control Order (June to September 2021) on 1076 processed foods from selected Malaysian hypermarkets, that were located within 10 km of the researcher’s residence to ensure accessibility amid the COVID-19 pandemic movement restrictions. Additionally, online platforms were used to supplement any missing data. Nutritional and ingredient information were collected from packaging, and foods were classified by using the FAO/WHO Food Standards CODEX Alimentarius. Over half (50.8%) of the surveyed products contained MSG. Results found that MSG-containing products had a significantly higher sodium levels (2812.2 ± 5191.4 mg/100 g) than those without (1372.2 ± 1541.4 mg/100 g) (p < 0.001). Additionally, 14.4% of MSG-free products were labelled as ‘No Added MSG’, while products with MSG were more likely to contain other umami enhancers (p < 0.001). Compliance with MSG declaration regulations was 61%. In conclusion, MSG was present in half of the surveyed products. MSG-containing products were more likely to have higher sodium content and include other flavour enhancers. Future research should analyse the actual MSG as well as sodium content and explore alternative sodium reduction strategies.

Iron deficiency anemia is a major health problem worldwide. Iron is an essential micronutrient in the human body; its demand increases with fetal growth and gestation. Although it has been reported that glucose metabolism is also affected by iron deficiency, only few studies have investigated the influence of iron deficiency during gestation and in offspring. In this study, glucose metabolism in newborns was investigated in terms of maternal iron deficiency prior to pregnancy in a rat model. Briefly, rats were divided into control (CL) and iron deficiency (ID) groups. The levels of serum glucose and insulin and the protein expression of liver GLUT2 in neonates born to dams in the ID group increased. In contrast, the mRNA and protein expression levels of GLUT2 and GLUT4 in the skeletal muscle tended to decrease. In addition, the expression of p-Akt (Thr308), which is involved in GLUT4 membrane translocation, decreased, suggesting that GLUT4 translocation to the plasma membrane may not have been sufficiently promoted. These results suggest that maternal iron deficiency may influence glucose metabolism in neonates and potentially increase the risk of developing metabolic abnormalities and lifestyle-related diseases later in life.

This pilot cross-sectional study, conducted in two public hospitals in Malawi, assessed gestational diabetes mellitus (GDM) in pregnant women attending antenatal clinics and compared their dietary quality and food group consumption before and during pregnancy. The study targeted women aged 18 to 49 years within 24 to 28 weeks of gestation. GDM was diagnosed according to the International Association of Diabetes and Pregnancy Study Group criteria and assessed dietary quality before and during pregnancy using a 30-day qualitative food frequency questionnaire. We compared changes in dietary quality and specific food group mean scores using paired t-tests at p < 0.05. Of the 508 women enrolled, 22.7% were diagnosed with GDM. The overall diet quality significantly decreased during pregnancy compared to before; a similar trend was observed in women diagnosed with GDM compared to those without GDM (p < 0.0001). Among women with GDM, the mean score of the following food groups significantly (p < 0.05) decreased during pregnancy: cruciferous vegetables, deep orange vegetables and tubers, citrus fruits, deep orange fruits, other fruits, nuts and seeds, poultry, fish, low fat dairy, whole grains, and liquid oils and significantly (p < 0.05) increased in the following food groups; red meat, processed meat, sugar-sweetened beverages, sweets, sugary snacks and ice cream. In conclusion, GDM is prevalent in Malawian women enrolled in this study and is coupled with inadequate dietary quality, especially during pregnancy. Since dietary quality is pivotal to GDM management, more in-depth longitudinal dietary studies are needed to inform nutritional interventions to prevent and better manage GDM.

This qualitative descriptive study aimed to explore dietary habits among healthcare workers during night shifts and to identify individual and environmental factors that influence their dietary behaviour during night shifts. Individual semi-structured interviews were conducted with twenty-five healthcare night female workers, which were recruited via email invitations from managers and posters placed in central workplaces at a university medical centre in the Netherlands. The interview protocol was developed following an integrated behaviour change model focusing on individual (I-Change model, i.e., awareness, motivation, intention, and ability) and environmental (Environmental Research framework for weight Gain prevention at environmental level (EnRG), i.e., physical, policy-related, economic, and sociocultural) factors. Inductive analyses were conducted to explore dietary habits, while deductive thematic analysis was applied to identify potential factors influencing dietary behaviour. Female healthcare workers in night shifts generally made poorer dietary choices during night shifts than during other shifts. Seven key themes were coded for dietary behaviour. Based on the domains of the integrated behaviour change model, four individual and five environmental key themes were established, within which 41 sub-themes were coded. Key individual factors included awareness (i.e., lack of knowledge about timing and type of consumption) and motivation (i.e., attitude and efficacy to eat healthy). Critical environmental factors included physical and sociocultural work environment, organisation of work, and lack of organisational policies. To conclude, future dietary interventions for healthcare night workers should target both individual behaviours and the workplace environment, with an emphasis on raising awareness and enhancing organisational policies to promote healthy dietary habits.

The 58th Annual Scientific Conference of the Nutrition Society of New Zealand, held in Christchurch in 2024, brought together 187 delegates under the theme ‘Kotahitanga: Bridging Research, Industry and Practice’. This theme reflected the society’s commitment to uniting diverse sectors to address key nutrition challenges across the life course. Kotahitanga refers to unity and collective action. Topics included nutrition in ageing and chronic disease, infant and toddler nutrition, gut health, sustainable food systems and food safety. Presentations on sarcopenia and Parkinson’s disease emphasised the need for greater awareness and tailored nutrition strategies for older adults. The Muriel Bell Lecture celebrated the legacy of New Zealand’s first State Nutritionist and called for continued leadership in evidence-based nutrition and encouraged nutritionists to communicate research to the public. A panel on science communication offered practical strategies for engaging the public and countering misinformation. The conference reinforced the importance of collaboration, advocacy and practical application in advancing nutrition.

2,3-Diphosphoglycerate (2,3-DPG), found primarily in red blood cells, plays a key role in regulating hemoglobin’s (Hb) affinity for oxygen. Increased 2,3-DPG levels shift the oxygen dissociation curve to the right, reducing Hb’s oxygen affinity and enhancing oxygen delivery to tissues—particularly important in conditions like anemia and high-altitude adaptation. Despite its physiological significance, research on 2,3-DPG is outdated and limited. This review aims to summarize current knowledge and identify research gaps. Measuring 2,3-DPG is challenging due to its instability and the need for careful sample handling. Chromatography and enzymatic methods are commonly used. Several factors influence 2,3-DPG levels, including diet, physiological state, and disease. Dietary phosphorus, for example, can acutely affect 2,3-DPG levels, though the impact of different meal compositions remains unexplored. Age, pregnancy, and physical activity also modulate 2,3-DPG, yet little is known about its role in infants and children. While changes in 2,3-DPG levels under various pathological conditions have been described, the molecular mechanisms behind these alterations remain poorly understood and warrant further investigation.

Statins are effective drugs for lowering hypercholesterolemia and preventing cardiovascular diseases. They can cause various side effects, in particular statin-associated muscle symptoms (SAMS) associated with mitochondrial dysfunction and micronutrient depletion. The aim of this systematic review and meta-analysis was to investigate the efficacy of a supplementation with Coenzyme Q10 (CoQ10) against SAMS in statin-treated patients. A systematic literature search was performed in Medline and Cochrane Library in August 2024. Studies were selected for a meta-analysis according to the following criteria: randomised controlled trials (RCTs), adults taking statins (any type and dose), supplementation of CoQ10, a comparable control group, and muscle pain as outcome criterion. Cochrane Risk of Bias tool was used for bias assessment. Seven RCTs with 389 patients in total were included in this meta-analysis. The selected studies included 35 to 76 patients and had a duration ranging from 30 to 90 days with CoQ10 dosages ranging from 100 to 600 mg per day. Results show a significant reduction of SAMS in four trials and no significant change in three trials. Overall, a significant reduction in SAMS, measured as pain intensity, after CoQ10 supplementation was found: weighted mean difference (WMD) −0.96 (95% Confidence Interval −1.88; −0.03), p < 0.05. Supplementation of CoQ10 can reduce muscle pain in patients with SAMS, which is relevant for their well-being and treatment continuation. More research is needed for evidence-based recommendations.

Foodservice provision is a key contributor to both dietary intake and food waste production(1). The development of ‘root-to-tip’ recipes in foodservice that incorporate more of the plant (i.e. peels and stalks) is being explored to reduce the climate impact of food waste(1) and improve suboptimal population intakes of fruits and vegetables, which provide useful sources of dietary fibre associated with lower risk of all-cause mortality(2). However, given low peels and stalks consumption in the UK(3), the extent to which ‘root-to-tip’ dishes may just shift food waste along the supply chain by increasing plate waste is unknown. The aim of this study is to understand the acceptability of ‘root-to-tip’ dining by exploring consumer attitudes towards food waste and perceived barriers and enablers to eating peels and stalks.

In-person focus groups were conducted at a UK university with current students and employees. Convenience sampling was used to recruit between five to eight participants across six focus groups. A semi-structured topic guide with open-ended questions was developed to facilitate discussion. Discussions were audio recorded, transcribed verbatim and an inductive thematic analysis undertaken. The research protocol was approved by the King’s College London Research Ethics Committee (Ref: MRA-24/25-46016; LRS/DP- 24/25-46017)

Six focus group discussions were conducted with forty participants (November 2024 to January 2025), primarily aged 18-25 years (53%) and female (75%). Six preliminary themes were identified: 1) food waste as a structural issue; 2) personal food waste awareness and the intention-behaviour gap; 3) the role of social modelling in ‘root-to-tip’ behaviours; 4) safety and edibility concerns around peels and stalks; 5) knowledge as a facilitator for ‘root-to-tip’ adoption; and 6) the importance of sensory appeal. These themes illustrate consumers’ perception of food waste as primarily occurring up the supply chain prior to the preparation stage, with structural barriers to its reduction. Participants perceive a growing societal and personal consciousness of food waste and desire to reduce its associated negative consequences. However, results highlight social and personal barriers, such as cost and convenience, which may contribute to an intention-behaviour gap. These barriers were referenced regarding the use of peels and stalks specifically, with upbringing, social modelling and food habits described as factors influencing consumption. Improving awareness of the safety and edibility of peels and stalks and practical knowledge related to their use may facilitate adoption of ‘root-to-tip’ behaviours. Anticipation of an unappealing sensory experience was described as a deterrent for consuming ‘root-to-tip’ dishes. Therefore, ensuring ‘root-to-tip’ dishes have sensory appeal is important to increase acceptability and prevent plate waste.

Our findings contribute to the understanding of attitudes towards food waste reduction practices at the preparation stage, in particular the use of peels and stalks, and highlight a need for increased knowledge to facilitate behaviour adoption.

Low fruit and vegetable (FV) intake is a public health concern in Malta, where more than one in four adults are living with obesity and only approximately 12% meet the recommended five-a-day intake (1). Socioeconomic disparities can contribute to a poor diet, with international evidence pointing to disadvantaged groups consuming fewer FV (2). The main aims of this local study were to assess FV intakes, perceptions and drivers including barriers, among adults residing in Malta.

This cross-sectional study used an anonymised, convenience sampling design with an online survey (via Google Forms) disseminated on social networks in April-June 2024. The questionnaire (33 items) covered demographics, FV consumption frequency, barriers and suggested improvements. Ethical approval was obtained from the University’s Faculty Research Ethics Committee (FREC ID: FHS-2023-00664). Chi-square tests (or Fisher- Freeman-Halton Exact tests) and Spearman’s correlations were utilised for analysis, and with cross-tabulations used for suggestions for increased consumption.

315 respondents returned the survey (mean age 44.5 years, range 18–65 years; 72% female) and with a mean body mass index (BMI) of 26.4 kg/m2 (SD= 5.66). Mean daily consumption was 1.7 and 1.8 FV portions respectively. Age was positively correlated with fruit intake (p=0.001), with older adults consuming fruit more frequently, but vegetable intake showed no significant correlation with age (p=0.39). Participants in lower income brackets were significantly more likely to report cost as a barrier to FV consumption (p=0.001) than those in higher-incomes. Comparing two districts with contrasting high and low-at-risk-of-poverty (ARP) rates classified according to 2022 statistics (National Statistics Office, NSO, 2023)(3), higher proportions of Northern Harbour respondents had higher incomes despite living in a higher ARP district, and reported earning over €50.1k annually (30.7%) compared to 21.9% in the South Eastern (low-ARP) district, whereas participants earning between €15.1–€20k were more represented in the South Eastern district (21.9%) than in Northern Harbour (1.8%). These income differences were significant (p=0.005). Suggested community improvements for FV access based on income levels revealed that a majority of lower-income participants looked for lower prices (55.6% in <€10k income bracket). In contrast, lower proportions of higher-income participants were concerned with cost (40.7% in >€50.1k bracket) and a quarter reported no community improvements needed. Cost was more frequently reported as a barrier to FV consumption (p<0.001) among non-EU participants (44.4%) and Maltese participants (41.3%) compared to other EU nationals (14.3%).

In conclusion, Maltese adults’ FV intakes fall short of dietary recommendations, and affordability barriers affect those in less affluent groups, reflecting socioeconomic barriers exist for FV consumption. There is a need to focus on targeted approaches such as providing subsidies for low-income pockets and different age groups within communities and different nationalities, regardless of district, in an effort to improve FV consumption in Malta.